KEGG   PATHWAY: sace00630
Entry
sace00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Allosaccharopolyspora coralli
Class
Metabolism; Carbohydrate metabolism
Pathway map
sace00630  Glyoxylate and dicarboxylate metabolism
sace00630

Module
sace_M00012  Glyoxylate cycle [PATH:sace00630]
sace_M00621  Glycine cleavage system [PATH:sace00630]
sace_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:sace00630]
Other DBs
GO: 0046487 0043648
Organism
Allosaccharopolyspora coralli [GN:sace]
Gene
GIY23_06585  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
GIY23_01425  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
GIY23_10120  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
GIY23_19940  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
GIY23_10815  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
GIY23_02620  citrate synthase [KO:K01647] [EC:2.3.3.1]
GIY23_02675  citrate synthase [KO:K01647] [EC:2.3.3.1]
GIY23_10665  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
GIY23_10405  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
GIY23_18365  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
GIY23_17075  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
GIY23_17935  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
GIY23_22200  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
GIY23_05290  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
GIY23_13295  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
GIY23_13315  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
GIY23_13445  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
GIY23_03780  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
GIY23_17945  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
GIY23_19075  ATP-grasp domain-containing protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
GIY23_19055  methylmalonyl-CoA carboxyltransferase [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
GIY23_07120  acyl-CoA carboxylase subunit beta [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
GIY23_15565  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
GIY23_15570  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
GIY23_18380  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
GIY23_10175  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
GIY23_18375  FAD-binding protein [KO:K11472] [EC:1.1.99.14]
GIY23_18370  4Fe-4S dicluster domain-containing protein [KO:K11473] [EC:1.1.99.14]
GIY23_01230  catalase [KO:K03781] [EC:1.11.1.6]
GIY23_06960  catalase [KO:K03781] [EC:1.11.1.6]
GIY23_09100  D-glycerate dehydrogenase [KO:K00015] [EC:1.1.1.26]
GIY23_02480  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
GIY23_12060  aminotransferase class V-fold PLP-dependent enzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
GIY23_07405  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
GIY23_07455  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
GIY23_11680  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
GIY23_13975  aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme [KO:K00600] [EC:2.1.2.1]
GIY23_15935  aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme [KO:K00600] [EC:2.1.2.1]
GIY23_10280  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
GIY23_15930  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
GIY23_15780  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
GIY23_07495  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
GIY23_18430  gcvH; glycine cleavage system protein GcvH [KO:K02437]
GIY23_10260  gcvH; glycine cleavage system protein GcvH [KO:K02437]
GIY23_11900  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
GIY23_11910  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
GIY23_11905  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
GIY23_15365  glycerate kinase [KO:K00865] [EC:2.7.1.165]
GIY23_00340  glycerate kinase [KO:K00865] [EC:2.7.1.165]
GIY23_19910  glycerate kinase [KO:K00865] [EC:2.7.1.165]
GIY23_11895  glycerate kinase [KO:K00865] [EC:2.7.1.165]
GIY23_15380  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
GIY23_07850  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
GIY23_18465  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
GIY23_05840  NAD-dependent formate dehydrogenase [KO:K00122] [EC:1.17.1.9]
GIY23_13905  molybdopterin-dependent oxidoreductase [KO:K00123] [EC:1.17.1.9]
GIY23_13900  4Fe-4S dicluster domain-containing protein [KO:K00124]
GIY23_14005  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
GIY23_12080  acetamidase/formamidase family protein [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
sace00010  Glycolysis / Gluconeogenesis
sace00020  Citrate cycle (TCA cycle)
sace00030  Pentose phosphate pathway
sace00053  Ascorbate and aldarate metabolism
sace00071  Fatty acid degradation
sace00230  Purine metabolism
sace00250  Alanine, aspartate and glutamate metabolism
sace00260  Glycine, serine and threonine metabolism
sace00620  Pyruvate metabolism
sace00710  Carbon fixation by Calvin cycle
sace00750  Vitamin B6 metabolism
sace00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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