KEGG   PATHWAY: sci00630
Entry
sci00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces collinus
Class
Metabolism; Carbohydrate metabolism
Pathway map
sci00630  Glyoxylate and dicarboxylate metabolism
sci00630

Module
sci_M00621  Glycine cleavage system [PATH:sci00630]
sci_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:sci00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces collinus [GN:sci]
Gene
B446_29110  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
B446_20425  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
B446_29270  malate synthase [KO:K01638] [EC:2.3.3.9]
B446_22630  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
B446_14505  gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
B446_17175  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
B446_27320  citrate synthase [KO:K01647] [EC:2.3.3.1]
B446_27325  citrate synthase [KO:K01647] [EC:2.3.3.1]
B446_28170  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
B446_12245  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
B446_30705  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
B446_10585  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
B446_04705  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
B446_16010  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
B446_25310  acyltransferase [KO:K00626] [EC:2.3.1.9]
B446_25305  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
B446_29765  methylmalonyl-CoA mutase large subunit [KO:K14447] [EC:5.4.99.63]
B446_23085  acyl-CoA carboxylase complex A subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
B446_23110  propionyl-CoA carboxylase complex B subunit [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
B446_23105  hypothetical protein [KO:K27095]
B446_27670  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
B446_27675  methylmalonyl-CoA mutase subunit beta [KO:K01847] [EC:5.4.99.2]
B446_22855  methylmalonyll-CoA mutase [KO:K01848] [EC:5.4.99.2]
B446_15285  (S)-2-hydroxy-acid oxidase [KO:K00104] [EC:1.1.99.14]
B446_24525  bromoperoxidase-catalase [KO:K03781] [EC:1.11.1.6]
B446_29140  catalase [KO:K03781] [EC:1.11.1.6]
B446_17365  hydrolase [KO:K01091] [EC:3.1.3.18]
B446_11515  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
B446_11600  glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
B446_11780  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
B446_08345  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
B446_31015  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
B446_25635  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
B446_25145  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
B446_22710  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
B446_07100  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
B446_25645  gcvT; glycine cleavage system aminomethyltransferase T [KO:K00605] [EC:2.1.2.10]
B446_11425  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
B446_25640  glycine cleavage system protein H [KO:K02437]
B446_29125  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
B446_29150  oxidoreductase [KO:K01816] [EC:5.3.1.22]
B446_29145  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
B446_29735  glycerate kinase [KO:K00865] [EC:2.7.1.165]
B446_12035  2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
B446_24845  kgd; alpha-ketoglutarate decarboxylase [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
B446_03810  molybdopterin oxidoreductase Fe4S4 region [KO:K00123] [EC:1.17.1.9]
B446_03815  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
B446_03790  4Fe-4S ferredoxin [KO:K00124]
B446_08690  hypothetical protein [KO:K00127]
B446_17105  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
sci00010  Glycolysis / Gluconeogenesis
sci00020  Citrate cycle (TCA cycle)
sci00030  Pentose phosphate pathway
sci00053  Ascorbate and aldarate metabolism
sci00071  Fatty acid degradation
sci00230  Purine metabolism
sci00250  Alanine, aspartate and glutamate metabolism
sci00260  Glycine, serine and threonine metabolism
sci00620  Pyruvate metabolism
sci00710  Carbon fixation by Calvin cycle
sci00750  Vitamin B6 metabolism
sci00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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