KEGG   PATHWAY: scin00630
Entry
scin00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces cinereoruber
Class
Metabolism; Carbohydrate metabolism
Pathway map
scin00630  Glyoxylate and dicarboxylate metabolism
scin00630

Module
scin_M00621  Glycine cleavage system [PATH:scin00630]
scin_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:scin00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces cinereoruber [GN:scin]
Gene
CP977_27520  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
CP977_30935  acyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
CP977_16135  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
CP977_27640  malate synthase A [KO:K01638] [EC:2.3.3.9]
CP977_21165  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
CP977_12180  citrate synthase [KO:K01647] [EC:2.3.3.1]
CP977_19870  citrate synthase [KO:K01647] [EC:2.3.3.1]
CP977_26495  acnA; aconitate hydratase AcnA [KO:K27802] [EC:4.2.1.3 4.2.1.99]
CP977_23820  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
CP977_28735  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
CP977_31090  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
CP977_13750  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
CP977_23815  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
CP977_28230  protein meaA [KO:K14447] [EC:5.4.99.63]
CP977_21610  biotin/lipoyl-binding protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
CP977_21630  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
CP977_21625  acyl-CoA carboxylase subunit epsilon [KO:K27095]
CP977_29580  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
CP977_29585  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
CP977_30270  methylaspartate mutase [KO:K19268] [EC:5.4.99.1]
CP977_30265  methylaspartate mutase [KO:K01846] [EC:5.4.99.1]
CP977_13030  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
CP977_23010  catalase [KO:K03781] [EC:1.11.1.6]
CP977_27560  catalase [KO:K03781] [EC:1.11.1.6]
CP977_32180  catalase [KO:K03781] [EC:1.11.1.6]
CP977_12725  phosphonatase-like hydrolase [KO:K01091] [EC:3.1.3.18]
CP977_19525  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
CP977_30425  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CP977_07015  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CP977_09920  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
CP977_09965  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CP977_10125  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CP977_21240  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
CP977_23665  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
CP977_24125  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
CP977_05860  gcvP; glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
CP977_24135  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
CP977_09830  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
CP977_17875  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
CP977_24130  gcvH; glycine cleavage system protein GcvH [KO:K02437]
CP977_27545  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
CP977_27570  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
CP977_27565  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
CP977_28160  glycerate kinase [KO:K00865] [EC:2.7.1.165]
CP977_10365  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
CP977_23420  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
CP977_20015  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
scin00010  Glycolysis / Gluconeogenesis
scin00020  Citrate cycle (TCA cycle)
scin00030  Pentose phosphate pathway
scin00053  Ascorbate and aldarate metabolism
scin00071  Fatty acid degradation
scin00230  Purine metabolism
scin00250  Alanine, aspartate and glutamate metabolism
scin00260  Glycine, serine and threonine metabolism
scin00620  Pyruvate metabolism
scin00710  Carbon fixation by Calvin cycle
scin00750  Vitamin B6 metabolism
scin00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

DBGET integrated database retrieval system