KEGG   PATHWAY: sco02024
Entry
sco02024                    Pathway                                
Name
Quorum sensing - Streptomyces coelicolor
Description
Quorum sensing (QS) is a regulatory system that allows bacteria to share information about cell density and adjust gene expression accordingly. All QS bacteria produce and release chemical signal molecules called autoinducers (AIs) that increase in concentration as a function of cell density. The most commonly studied AIs belong to one of the following three categories: acylated homoserine lactones, also referred to as AI-1, used by Gram-negative bacteria; peptide signals, used by Gram-positive bacteria; and AI-2, used by both Gram-negative and Gram-positive bacteria. QS can be divided into at least 4 steps: production of AIs by the bacterial cell; release of AIs, either actively or passively, into the surrounding environment; recognition of AIs by specific receptors; and leading to changes in gene regulation once they exceed a threshold concentration. The processes controlled by QS include virulence, competence, conjugation, antibiotic production, motility, sporulation, and biofilm formation.
Class
Cellular Processes; Cellular community - prokaryotes
Pathway map
sco02024  Quorum sensing
sco02024

Other DBs
GO: 0009372
Organism
Streptomyces coelicolor [GN:sco]
Gene
SCO2043  SC4G6.12c; anthranilate synthase component I [KO:K01657] [EC:4.1.3.27]
SCO3214  SCE8.07c; anthranilate synthase component I [KO:K01657] [EC:4.1.3.27]
SCO3213  SCE8.06c; anthranilate synthase component II [KO:K01658] [EC:4.1.3.27]
SCO2115  aroH; 2-dehydro-3-deoxyphosphoheptonate aldolase [KO:K01626] [EC:2.5.1.54]
SCO3210  SCE8.03c; 3-deoxy-7-phosphoheptulonate synthase [KO:K01626] [EC:2.5.1.54]
SCO2117  SC6E10.11; anthranilate synthase [KO:K13063] [EC:2.6.1.86]
SCO5872  kdpE; turgor pressure regulator [KO:K07667]
SCO3416  gad; glutamate decarboxylase [KO:K01580] [EC:4.1.1.15]
SCO3456  SCE46.13c; ABC transporter substrate-binding protein [KO:K02055]
SCO3454  SCE46.11c; ABC-transporter membrane protein [KO:K02053]
SCO3455  SCE46.12c; ABC-transporter transport protein [KO:K02054]
SCO2008  SC7H2.22; branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
SCO7185  SC8A11.13; branched amino acid binding hypothetical protein [KO:K01999]
SCO4401  SCD10.33c; lipoprotein [KO:K01999]
SCO0708  SCF42.18c; branched-chain amino acid ABC transporter [KO:K01997]
SCO2009  SC7H2.23; branched-chain amino acid ABC transporter permease [KO:K01997]
SCO7183  SC8A11.11; branched amino acid transport system permease [KO:K01997]
SCO0707  SCF42.17c; branched-chain amino acid ABC transporter permease [KO:K01998]
SCO2010  SC7H2.24; branched-chain amino acid ABC transporter permease [KO:K01998]
SCO7184  SC8A11.12; branched amino acid transport system permease [KO:K01998]
SCO0709  SCF42.19c; ABC transporter ATP-binding protein [KO:K01995]
SCO2011  SC7H2.25; ABC transporter ATP-binding protein [KO:K01995]
SCO7181  SC8A11.09; ABC transporter ATP-binding protein [KO:K01995]
SCO0710  SCF42.20c; ABC transporter ATP-binding protein [KO:K01996]
SCO2012  SC7H2.26; ABC transporter ATP-binding protein [KO:K01996]
SCO7182  SC8A11.10; ABC transporter ATP-binding protein [KO:K01996]
SCO1880  SCI39.27c; pectate lyase [KO:K01728] [EC:4.2.2.2]
SCO2821  SCBAC17F8.12c; pectate lyase [KO:K01728] [EC:4.2.2.2]
SCO2474  SC7A8.13; metalloproteinase [KO:K20273]
SCO2131  SC6G10.04; long chain fatty acid CoA ligase [KO:K01897] [EC:6.2.1.3]
SCO6968  SC6F7.21; long-chain-fatty-acid-CoA ligase [KO:K01897] [EC:6.2.1.3]
SCO2720  SCC46.05c; long-chain fatty acid ligase [KO:K01897] [EC:6.2.1.3]
SCO6552  SC4B5.02c; long-chain-fatty-acid-CoA ligase [KO:K01897] [EC:6.2.1.3]
SCO2561  SCC77.28c; long-chain fatty-acid CoA ligase [KO:K01897] [EC:6.2.1.3]
SCO4503  SCD35.10; long-chain-fatty acid CoA ligase [KO:K01897] [EC:6.2.1.3]
SCO1330  2SCG61.12c; fatty acid CoA ligase [KO:K01897] [EC:6.2.1.3]
SCO7329  SC4G10.08c; long-chain-fatty-acid-CoA ligase [KO:K01897] [EC:6.2.1.3]
SCO3571  SCH17.05; transcriptional regulator [KO:K10914]
SCO6234  manA; beta-mannosidase [KO:K01218] [EC:3.2.1.78]
SCO0554  manA; beta-mannosidase [KO:K01218] [EC:3.2.1.78]
SCO6655  ribA2; GTP cyclohydrolase II [KO:K01497] [EC:3.5.4.25]
SCO2687  ribA; GTP cyclohydrolase II [KO:K01497] [EC:3.5.4.25]
SCO2695  SCC61A.16; hypothetical protein [KO:K20333]
SCO2688  ribD; riboflavin-specific deaminase [KO:K11752] [EC:3.5.4.26 1.1.1.193]
SCO5117  SC9E12.02; peptide transport system peptide-binding protein [KO:K15580]
SCO5118  SC9E12.03; peptide transport system integral membrane protein [KO:K15581]
SCO5119  SC9E12.04; peptide transport system integral membrane protein [KO:K15582]
SCO5120  SC9E12.05; peptide transport system ATP-binding protein [KO:K15583]
SCO5121  SC9E12.06; peptide transport system ATP-binding protein [KO:K10823]
SCO1344  2SCG61.26c; solute binding transport lipoprotein [KO:K02035]
SCO1655  SCI41.38c; lipoprotein oligopeptide binding protein [KO:K02035]
SCO5716  SC3C3.02c; peptide transport system peptide binding protein [KO:K02035]
SCO7677  SC4C2.12; solute-binding protein [KO:K02035]
SCO7563  SC5F1.17; ABC transporter solute binding lipoprotein [KO:K02035]
SCO5113  bldKB; ABC transporter lipoprotein BldKB [KO:K02035]
SCO6644  SC4G2.18; solute-binding lipoprotein [KO:K02035]
SCO5477  SC2A11.11; oligopeptide-binding lipoprotein [KO:K02035]
SCO6451  SC9B5.18; substrate binding protein [KO:K02035]
SCO5110  SCBAC31E11.06; lipoprotein [KO:K02035]
SCO6114  SC9B2.01c; peptide-binding transport protein [KO:K02035]
SCO6452  SC9B5.19; transport permease [KO:K02033]
SCO7678  SC4C2.13; metal transport integral membrane protein [KO:K02033]
SCO5114  bldKC; ABC transporter integral membrane protein BldKC [KO:K02033]
SCO6645  SC4G2.19; transport system permease [KO:K02033 K02034]
SCO5478  SC2A11.12; oligopeptide transport system integral membrane protein [KO:K02033]
SCO5715  SC3C3.01c; peptide transport system permease [KO:K02033]
SCO6113  SCBAC1A6.37c; peptide ABC transporter integral membrane protein [KO:K02033]
SCO7564  SC5F1.18; oligopeptide ABC transporter integral membrane protein [KO:K02033]
SCO5476  SC2A11.10; oligopeptide transport integral membrane protein [KO:K02034]
SCO6112  SCBAC1A6.36c; oligopeptide ABC transporter integral membrane protein [KO:K02034]
SCO5714  SC9F2.02; peptide transport permease [KO:K02034]
SCO6453  SC9B5.20; transport permease [KO:K02034]
SCO7679  SC4C2.14; transport system integral membrane protein [KO:K02034]
SCO7565  SC5F1.19; oligopeptide ABC transporter integral membrane protein [KO:K02034]
SCO5112  bldKA; ABC transporter integral membrane protein BldKA [KO:K02034]
SCO6111  SCBAC1A6.35c; oligopeptide ABC transporter ATP-binding protein [KO:K02031 K02032]
SCO5713  SC9F2.03; ABC transporter ATP-binding protein [KO:K02031]
SCO7680  SC4C2.15; ABC transporter ATP-binding protein [KO:K02031 K02032]
SCO6454  SC9B5.21; ABC transporter ATP-binding protein [KO:K02031]
SCO7566  SC5F1.20; oligopeptide ABC transporter ATP-binding protein [KO:K02031]
SCO5479  SC2A11.13; oligopeptide ABC transporter ATP-binding protein [KO:K02031]
SCO5115  bldKD; ABC transporter intracellular ATPase subunit BldKD [KO:K02031]
SCO6455  SC9B5.22; ABC transporter ATP-binding protein [KO:K02032]
SCO7567  SC5F1.21; oligopeptide ABC transporter ATP-binding protein [KO:K02032]
SCO5480  SC2A11.14; oligopeptide ABC transporter ATP-binding protein [KO:K02032]
SCO5116  bldKE; peptide transport system ATP-binding subunit [KO:K02032]
SCO3883  StH24.05; inner membrane protein translocase component YidC [KO:K03217]
SCO2851  SCE20.25c; hypothetical protein [KO:K03217]
SCO6160  SC1A9.24c; bifunctional preprotein translocase subunit SecD/SecF [KO:K12257]
SCO4646  secE; preprotein translocase subunit SecE [KO:K03073]
SCO1944  secG; preprotein translocase subunit SecG [KO:K03075]
SCO4722  secY; preprotein translocase subunit SecY [KO:K03076]
SCO1517  SCL2.07c; hypothetical protein [KO:K03210]
SCO3005  azi; preprotein translocase subunit SecA [KO:K03070] [EC:7.4.2.8]
SCO5580  SC7A1.24; docking protein [KO:K03110]
SCO5586  ffh; signal recognition particle protein [KO:K03106] [EC:3.6.5.4]
SCO6691  SC4C6.01; phospholipase C [KO:K01114] [EC:3.1.4.3]
SCO0269  SCF1.11; hypothetical protein [KO:K20483]
SCO6930  SC1G8.02c; hypothetical protein [KO:K20483]
SCO0270  SCF1.12; hypothetical protein [KO:K20484]
SCO6929  SC1B2.35c; hypothetical protein [KO:K20484]
Compound
C00007  Oxygen
C00009  Orthophosphate
C00059  Sulfate
C00232  Succinate semialdehyde
C00334  4-Aminobutanoate
C00547  L-Noradrenaline
C00788  L-Adrenaline
C01019  L-Fucose
C11837  N-Butyryl-L-homoserine lactone
C11841  N-(3-Oxooctanoyl)homoserine lactone
C11844  N-Heptanoylhomoserine lactone
C11845  N-(3-Hydroxy-7-cis-tetradecenoyl)homoserine lactone
C11848  2-Heptyl-3-hydroxy-quinolone
C16421  AI-2
C16463  3',5'-Cyclic diGMP
C16640  CAI-1
C18049  N-Acyl-L-homoserine lactone
C18206  cis-11-Methyl-2-dodecenoic acid
C20643  2-Heptyl-4(1H)-quinolone
C20677  N-(4-Coumaroyl)-L-homoserine lactone
C20959  (4S)-4-Hydroxy-5-phosphooxypentane-2,3-dione
C21195  N-(3-Hydroxybutanoyl)-L-homoserine lactone
C21197  N-Hexanoyl-L-homoserine lactone
C21198  N-(3-Oxohexanoyl)-L-homoserine lactone
C21199  N-Octanoyl-L-homoserine lactone
C21200  N-3-Hydroxyoctanoyl-L-homoserine lactone
C21201  N-3-Oxo-dodecanoyl-L-homoserine lactone
C21202  cis-2-Dodecenoic acid
C21220  AIP-1
C21221  CSP
C21222  CSP
C21223  Blp
C21224  SHP2
C21225  SHP3
C21226  cCF10
C21227  iCF10
C21228  cAD1
C21229  iAD1
C21230  ComX pheromone
C21231  PhrA pentapeptide
C21232  PhrC pentapeptide
C21233  PhrE pentapeptide
C21234  PhrF pentapeptide
C21235  PhrG pentapeptide
C21236  PhrH pentapeptide
C21237  PhrK pentapeptide
C21238  NprX peptide
C21239  PapR peptide
C21241  AIP-2
C21242  AIP-3
C21243  AIP-4
C21244  AgrD peptide
C21245  AgrD1 peptide
C21246  GBAP
C21382  R-THMF
Reference
PMID:22712853
  Authors
Pereira CS, Thompson JA, Xavier KB
  Title
AI-2-mediated signalling in bacteria.
  Journal
FEMS Microbiol Rev 37:156-81 (2013)
DOI:10.1111/j.1574-6976.2012.00345.x
Reference
PMID:23965960
  Authors
Verma SC, Miyashiro T
  Title
Quorum sensing in the squid-Vibrio symbiosis.
  Journal
Int J Mol Sci 14:16386-401 (2013)
DOI:10.3390/ijms140816386
Reference
PMID:24348467
  Authors
Norsworthy AN, Visick KL
  Title
Gimme shelter: how Vibrio fischeri successfully navigates an animal's multiple environments.
  Journal
Front Microbiol 4:356 (2013)
DOI:10.3389/fmicb.2013.00356
Reference
PMID:24065108
  Authors
Papaioannou E, Utari PD, Quax WJ
  Title
Choosing an appropriate infection model to study quorum sensing inhibition in Pseudomonas infections.
  Journal
Int J Mol Sci 14:19309-40 (2013)
DOI:10.3390/ijms140919309
Reference
PMID:20738404
  Authors
Heeb S, Fletcher MP, Chhabra SR, Diggle SP, Williams P, Camara M
  Title
Quinolones: from antibiotics to autoinducers.
  Journal
FEMS Microbiol Rev 35:247-74 (2011)
DOI:10.1111/j.1574-6976.2010.00247.x
Reference
PMID:25866808
  Authors
Rasamiravaka T, Labtani Q, Duez P, El Jaziri M
  Title
The formation of biofilms by Pseudomonas aeruginosa: a review of the natural and synthetic compounds interfering with control mechanisms.
  Journal
Biomed Res Int 2015:759348 (2015)
DOI:10.1155/2015/759348
Reference
PMID:11544214
  Authors
Whiteley M, Greenberg EP
  Title
Promoter specificity elements in Pseudomonas aeruginosa quorum-sensing-controlled genes.
  Journal
J Bacteriol 183:5529-34 (2001)
DOI:10.1128/JB.183.19.5529-5534.2001
Reference
PMID:11497469
  Authors
Chin-A-Woeng TF, van den Broek D, de Voer G, van der Drift KM, Tuinman S, Thomas-Oates JE, Lugtenberg BJ, Bloemberg GV
  Title
Phenazine-1-carboxamide production in the biocontrol strain Pseudomonas chlororaphis PCL1391 is regulated by multiple factors secreted into the growth medium.
  Journal
Mol Plant Microbe Interact 14:969-79 (2001)
DOI:10.1094/MPMI.2001.14.8.969
Reference
PMID:19696934
  Authors
Hughes DT, Clarke MB, Yamamoto K, Rasko DA, Sperandio V
  Title
The QseC adrenergic signaling cascade in Enterohemorrhagic E. coli (EHEC).
  Journal
PLoS Pathog 5:e1000553 (2009)
DOI:10.1371/journal.ppat.1000553
Reference
PMID:22144490
  Authors
Njoroge J, Sperandio V
  Title
Enterohemorrhagic Escherichia coli virulence regulation by two bacterial adrenergic kinases, QseC and QseE.
  Journal
Infect Immun 80:688-703 (2012)
DOI:10.1128/IAI.05921-11
Reference
PMID:23160491
  Authors
Pacheco AR, Curtis MM, Ritchie JM, Munera D, Waldor MK, Moreira CG, Sperandio V
  Title
Fucose sensing regulates bacterial intestinal colonization.
  Journal
Nature 492:113-7 (2012)
DOI:10.1038/nature11623
Reference
PMID:22778415
  Authors
Hirakawa H, Harwood CS, Pechter KB, Schaefer AL, Greenberg EP
  Title
Antisense RNA that affects Rhodopseudomonas palustris quorum-sensing signal receptor expression.
  Journal
Proc Natl Acad Sci U S A 109:12141-6 (2012)
DOI:10.1073/pnas.1200243109
Reference
PMID:14617175
  Authors
Danino VE, Wilkinson A, Edwards A, Downie JA
  Title
Recipient-induced transfer of the symbiotic plasmid pRL1JI in Rhizobium leguminosarum bv. viciae is regulated by a quorum-sensing relay.
  Journal
Mol Microbiol 50:511-25 (2003)
DOI:10.1046/j.1365-2958.2003.03699.x
Reference
PMID:12448738
  Authors
Wisniewski-Dye F, Downie JA
  Title
Quorum-sensing in Rhizobium.
  Journal
Antonie Van Leeuwenhoek 81:397-407 (2002)
DOI:10.1023/A:1020501104051
Reference
PMID:10368158
  Authors
Rodelas B, Lithgow JK, Wisniewski-Dye F, Hardman A, Wilkinson A, Economou A, Williams P, Downie JA
  Title
Analysis of quorum-sensing-dependent control of rhizosphere-expressed (rhi) genes in Rhizobium leguminosarum bv. viciae.
  Journal
J Bacteriol 181:3816-23 (1999)
DOI:10.1128/JB.181.12.3816-3823.1999
Reference
PMID:24550924
  Authors
Lang J, Faure D
  Title
Functions and regulation of quorum-sensing in Agrobacterium tumefaciens.
  Journal
Front Plant Sci 5:14 (2014)
DOI:10.3389/fpls.2014.00014
Reference
PMID:23710277
  Authors
Planamente S, Morera S, Faure D
  Title
In planta fitness-cost of the Atu4232-regulon encoding for a selective GABA-binding sensor in Agrobacterium.
  Journal
Commun Integr Biol 6:e23692 (2013)
DOI:10.4161/cib.23692
Reference
PMID:16943991
  Authors
Barnard AM, Salmond GP
  Title
Quorum sensing in Erwinia species.
  Journal
Anal Bioanal Chem 387:415-23 (2007)
DOI:10.1007/s00216-006-0701-1
Reference
PMID:17360277
  Authors
Barnard AM, Bowden SD, Burr T, Coulthurst SJ, Monson RE, Salmond GP
  Title
Quorum sensing, virulence and secondary metabolite production in plant soft-rotting bacteria.
  Journal
Philos Trans R Soc Lond B Biol Sci 362:1165-83 (2007)
DOI:10.1098/rstb.2007.2042
Reference
PMID:19843225
  Authors
Carlier A, Burbank L, von Bodman SB
  Title
Identification and characterization of three novel EsaI/EsaR quorum-sensing controlled stewartan exopolysaccharide biosynthetic genes in Pantoea stewartii ssp. stewartii.
  Journal
Mol Microbiol 74:903-13 (2009)
DOI:10.1111/j.1365-2958.2009.06906.x
Reference
PMID:7665477
  Authors
Beck von Bodman S, Farrand SK
  Title
Capsular polysaccharide biosynthesis and pathogenicity in Erwinia stewartii require induction by an N-acylhomoserine lactone autoinducer.
  Journal
J Bacteriol 177:5000-8 (1995)
DOI:10.1128/JB.177.17.5000-5008.1995
Reference
PMID:19761612
  Authors
O'Grady EP, Viteri DF, Malott RJ, Sokol PA
  Title
Reciprocal regulation by the CepIR and CciIR quorum sensing systems in Burkholderia cenocepacia.
  Journal
BMC Genomics 10:441 (2009)
DOI:10.1186/1471-2164-10-441
Reference
PMID:16041013
  Authors
Malott RJ, Baldwin A, Mahenthiralingam E, Sokol PA
  Title
Characterization of the cciIR quorum-sensing system in Burkholderia cenocepacia.
  Journal
Infect Immun 73:4982-92 (2005)
DOI:10.1128/IAI.73.8.4982-4992.2005
Reference
PMID:22949660
  Authors
Deng Y, Schmid N, Wang C, Wang J, Pessi G, Wu D, Lee J, Aguilar C, Ahrens CH, Chang C, Song H, Eberl L, Zhang LH
  Title
Cis-2-dodecenoic acid receptor RpfR links quorum-sensing signal perception with regulation of virulence through cyclic dimeric guanosine monophosphate turnover.
  Journal
Proc Natl Acad Sci U S A 109:15479-84 (2012)
DOI:10.1073/pnas.1205037109
Reference
PMID:23799665
  Authors
Suppiger A, Schmid N, Aguilar C, Pessi G, Eberl L
  Title
Two quorum sensing systems control biofilm formation and virulence in members of the Burkholderia cepacia complex.
  Journal
Virulence 4:400-9 (2013)
DOI:10.4161/viru.25338
Reference
PMID:21166386
  Authors
Deng Y, Wu J, Tao F, Zhang LH
  Title
Listening to a new language: DSF-based quorum sensing in Gram-negative bacteria.
  Journal
Chem Rev 111:160-73 (2011)
DOI:10.1021/cr100354f
Reference
PMID:21227698
  Authors
Ryan RP, Dow JM
  Title
Communication with a growing family: diffusible signal factor (DSF) signaling in bacteria.
  Journal
Trends Microbiol 19:145-52 (2011)
DOI:10.1016/j.tim.2010.12.003
Reference
PMID:15522077
  Authors
Kim J, Kim JG, Kang Y, Jang JY, Jog GJ, Lim JY, Kim S, Suga H, Nagamatsu T, Hwang I
  Title
Quorum sensing and the LysR-type transcriptional activator ToxR regulate toxoflavin biosynthesis and transport in Burkholderia glumae.
  Journal
Mol Microbiol 54:921-34 (2004)
DOI:10.1111/j.1365-2958.2004.04338.x
Reference
PMID:17376080
  Authors
Kim J, Kang Y, Choi O, Jeong Y, Jeong JE, Lim JY, Kim M, Moon JS, Suga H, Hwang I
  Title
Regulation of polar flagellum genes is mediated by quorum sensing and FlhDC in Burkholderia glumae.
  Journal
Mol Microbiol 64:165-79 (2007)
DOI:10.1111/j.1365-2958.2007.05646.x
Reference
PMID:21622734
  Authors
Stauff DL, Bassler BL
  Title
Quorum sensing in Chromobacterium violaceum: DNA recognition and gene regulation by the CviR receptor.
  Journal
J Bacteriol 193:3871-8 (2011)
DOI:10.1128/JB.05125-11
Reference
PMID:21504831
  Authors
Chen G, Swem LR, Swem DL, Stauff DL, O'Loughlin CT, Jeffrey PD, Bassler BL, Hughson FM
  Title
A strategy for antagonizing quorum sensing.
  Journal
Mol Cell 42:199-209 (2011)
DOI:10.1016/j.molcel.2011.04.003
Reference
PMID:16513747
  Authors
Hao G, Burr TJ
  Title
Regulation of long-chain N-acyl-homoserine lactones in Agrobacterium vitis.
  Journal
J Bacteriol 188:2173-83 (2006)
DOI:10.1128/JB.188.6.2173-2183.2006
Reference
PMID:20514483
  Authors
Savka MA, Le PT, Burr TJ
  Title
LasR receptor for detection of long-chain quorum-sensing signals: identification of N-acyl-homoserine lactones encoded by the avsI locus of Agrobacterium vitis.
  Journal
Curr Microbiol 62:101-10 (2011)
DOI:10.1007/s00284-010-9679-1
Reference
PMID:26579084
  Authors
Le KY, Otto M
  Title
Quorum-sensing regulation in staphylococci-an overview.
  Journal
Front Microbiol 6:1174 (2015)
DOI:10.3389/fmicb.2015.01174
Reference
PMID:18851841
  Authors
Queck SY, Jameson-Lee M, Villaruz AE, Bach TH, Khan BA, Sturdevant DE, Ricklefs SM, Li M, Otto M
  Title
RNAIII-independent target gene control by the agr quorum-sensing system: insight into the evolution of virulence regulation in Staphylococcus aureus.
  Journal
Mol Cell 32:150-8 (2008)
DOI:10.1016/j.molcel.2008.08.005
Reference
PMID:25714717
  Authors
Darkoh C, DuPont HL, Norris SJ, Kaplan HB
  Title
Toxin synthesis by Clostridium difficile is regulated through quorum signaling.
  Journal
MBio 6:e02569 (2015)
DOI:10.1128/mBio.02569-14
Reference
PMID:25824838
  Authors
Vidal JE, Shak JR, Canizalez-Roman A
  Title
The CpAL quorum sensing system regulates production of hemolysins CPA and PFO to build Clostridium perfringens biofilms.
  Journal
Infect Immun 83:2430-42 (2015)
DOI:10.1128/IAI.00240-15
Reference
PMID:19363118
  Authors
Ohtani K, Yuan Y, Hassan S, Wang R, Wang Y, Shimizu T
  Title
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Related
pathway
sco00405  Phenazine biosynthesis
sco02040  Flagellar assembly
KO pathway
ko02024   
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