KEGG   PATHWAY: scx00630
Entry
scx00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces sp. CdTB01
Class
Metabolism; Carbohydrate metabolism
Pathway map
scx00630  Glyoxylate and dicarboxylate metabolism
scx00630

Module
scx_M00621  Glycine cleavage system [PATH:scx00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces sp. CdTB01 [GN:scx]
Gene
AS200_22180  acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
AS200_11415  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
AS200_38600  acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
AS200_39895  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
AS200_11270  malate synthase A [KO:K01638] [EC:2.3.3.9]
AS200_19665  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
AS200_28685  type II citrate synthase [KO:K01647] [EC:2.3.3.1]
AS200_12850  citrate synthase/methylcitrate synthase [KO:K01647] [EC:2.3.3.1]
AS200_12855  citrate synthase [KO:K01647] [EC:2.3.3.1]
AS200_25785  citrate synthase/methylcitrate synthase [KO:K01647] [EC:2.3.3.1]
AS200_12450  acnA; aconitate hydratase [KO:K01681] [EC:4.2.1.3]
AS200_32860  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AS200_30930  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AS200_40365  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AS200_09145  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AS200_26995  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AS200_16480  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AS200_43230  crotonyl-CoA reductase [KO:K14446] [EC:1.3.1.85]
AS200_16485  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
AS200_10825  protein meaA [KO:K14447] [EC:5.4.99.63]
AS200_39320  methylmalonyl-CoA carboxyltransferase [KO:K01966] [EC:6.4.1.3 2.1.3.15]
AS200_19135  acetyl-/propionyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
AS200_19115  methylmalonyl-CoA carboxyltransferase [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
AS200_19120  hypothetical protein [KO:K27095]
AS200_19350  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
AS200_00925  methylaspartate mutase [KO:K19268] [EC:5.4.99.1]
AS200_00930  hypothetical protein [KO:K01846] [EC:5.4.99.1]
AS200_02925  methylaspartate mutase [KO:K01846] [EC:5.4.99.1]
AS200_39045  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
AS200_27815  FAD-linked oxidase [KO:K00104] [EC:1.1.99.14]
AS200_04605  catalase [KO:K03781] [EC:1.11.1.6]
AS200_11390  catalase [KO:K03781] [EC:1.11.1.6]
AS200_25545  haloacid dehalogenase [KO:K01091] [EC:3.1.3.18]
AS200_16800  haloacid dehalogenase [KO:K01091] [EC:3.1.3.18]
AS200_00605  hypothetical protein [KO:K01915] [EC:6.3.1.2]
AS200_01365  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
AS200_31615  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
AS200_31780  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
AS200_31870  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
AS200_08715  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
AS200_35530  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
AS200_38870  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
AS200_16670  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
AS200_19560  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
AS200_16125  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
AS200_36820  glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
AS200_16115  glycine cleavage system protein T [KO:K00605] [EC:2.1.2.10]
AS200_31970  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
AS200_16120  glycine cleavage system protein H [KO:K02437]
AS200_11400  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
AS200_11380  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
AS200_11385  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
AS200_10855  glycerate kinase [KO:K00865] [EC:2.7.1.165]
AS200_02050  keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
AS200_31220  keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
AS200_17315  kgd; alpha-ketoglutarate decarboxylase [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
AS200_06610  formate dehydrogenase [KO:K00123] [EC:1.17.1.9]
AS200_06605  4Fe-4S ferredoxin [KO:K00124]
AS200_35010  formate dehydrogenase [KO:K00127]
AS200_06865  formate dehydrogenase [KO:K00127]
AS200_38835  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
AS200_25850  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
AS200_10295  formyl-coenzyme A transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
scx00010  Glycolysis / Gluconeogenesis
scx00020  Citrate cycle (TCA cycle)
scx00030  Pentose phosphate pathway
scx00053  Ascorbate and aldarate metabolism
scx00071  Fatty acid degradation
scx00230  Purine metabolism
scx00250  Alanine, aspartate and glutamate metabolism
scx00260  Glycine, serine and threonine metabolism
scx00620  Pyruvate metabolism
scx00710  Carbon fixation by Calvin cycle
scx00750  Vitamin B6 metabolism
scx00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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