KEGG   PATHWAY: shau00630
Entry
shau00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces halobius
Class
Metabolism; Carbohydrate metabolism
Pathway map
shau00630  Glyoxylate and dicarboxylate metabolism
shau00630

Module
shau_M00012  Glyoxylate cycle [PATH:shau00630]
shau_M00621  Glycine cleavage system [PATH:shau00630]
shau_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:shau00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces halobius [GN:shau]
Gene
K9S39_37460  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
K9S39_21175  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
K9S39_02815  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
K9S39_37455  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
K9S39_11530  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
K9S39_18035  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
K9S39_28860  citrate synthase [KO:K01647] [EC:2.3.3.1]
K9S39_13185  citrate synthase/methylcitrate synthase [KO:K01647] [EC:2.3.3.1]
K9S39_13190  citrate synthase [KO:K01647] [EC:2.3.3.1]
K9S39_18400  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
K9S39_02255  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
K9S39_12720  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
K9S39_27175  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
K9S39_31380  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
K9S39_37340  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
K9S39_08125  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
K9S39_08230  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
K9S39_15480  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
K9S39_15485  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
K9S39_10770  protein meaA [KO:K14447] [EC:5.4.99.63]
K9S39_17520  ATP-grasp domain-containing protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
K9S39_17480  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
K9S39_17485  acyl-CoA carboxylase subunit epsilon [KO:K27095]
K9S39_08325  methylmalonyl-CoA mutase subunit beta [KO:K01847] [EC:5.4.99.2]
K9S39_08330  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
K9S39_17785  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
K9S39_28010  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
K9S39_00810  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
K9S39_11590  catalase [KO:K03781] [EC:1.11.1.6]
K9S39_16375  catalase [KO:K03781] [EC:1.11.1.6]
K9S39_17110  catalase [KO:K03781] [EC:1.11.1.6]
K9S39_12810  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
K9S39_18620  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
K9S39_31815  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
K9S39_31935  glutamine synthetase beta-grasp domain-containing protein [KO:K01915] [EC:6.3.1.2]
K9S39_32095  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
K9S39_35080  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
K9S39_07625  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
K9S39_09330  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
K9S39_15145  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
K9S39_15645  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
K9S39_17890  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
K9S39_37710  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
K9S39_15135  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
K9S39_32175  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
K9S39_12305  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
K9S39_15140  gcvH; glycine cleavage system protein GcvH [KO:K02437]
K9S39_02765  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
K9S39_02760  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
K9S39_11580  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
K9S39_02755  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
K9S39_11585  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
K9S39_18265  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
K9S39_10800  glycerate kinase [KO:K00865] [EC:2.7.1.165]
K9S39_31525  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
K9S39_11470  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
K9S39_16015  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
K9S39_18335  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
shau00010  Glycolysis / Gluconeogenesis
shau00020  Citrate cycle (TCA cycle)
shau00030  Pentose phosphate pathway
shau00053  Ascorbate and aldarate metabolism
shau00071  Fatty acid degradation
shau00230  Purine metabolism
shau00250  Alanine, aspartate and glutamate metabolism
shau00260  Glycine, serine and threonine metabolism
shau00620  Pyruvate metabolism
shau00710  Carbon fixation by Calvin cycle
shau00750  Vitamin B6 metabolism
shau00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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