KEGG   PATHWAY: smi00630
Entry
smi00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Sinorhizobium meliloti Rm41
Class
Metabolism; Carbohydrate metabolism
Pathway map
smi00630  Glyoxylate and dicarboxylate metabolism
smi00630

Module
smi_M00012  Glyoxylate cycle [PATH:smi00630]
smi_M00621  Glycine cleavage system [PATH:smi00630]
smi_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:smi00630]
Other DBs
GO: 0046487 0043648
Organism
Sinorhizobium meliloti Rm41 [GN:smi]
Gene
BN406_00337  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
BN406_03122  acsA2; Acetyl-coenzyme A synthetase 2 [KO:K01895] [EC:6.2.1.1]
BN406_02489  acsA3; probabable acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
BN406_03196  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
BN406_02912  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
BN406_01240  gltA; type II citrate synthase [KO:K01647] [EC:2.3.3.1]
BN406_03030  acnA; Aconitate hydratase [KO:K01681] [EC:4.2.1.3]
BN406_00541  vraB; Putative acetyl-CoA C-acetyltransferase vraB [KO:K00626] [EC:2.3.1.9]
BN406_03063  phbA; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BN406_00166  fadA; Putative acyltransferase Rv0859 [KO:K00626] [EC:2.3.1.9]
BN406_01442  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BN406_04528  thlA; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BN406_03062  phbB; Acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
BN406_01017  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
BN406_05250  Pcca; Propionyl-CoA carboxylase alpha chain, mitochondrial [KO:K01965] [EC:6.4.1.3]
BN406_05251  PCCB; Propionyl-CoA carboxylase beta chain, mitochondrial [KO:K01966] [EC:6.4.1.3 2.1.3.15]
BN406_06793  bccA; Acetyl-/propionyl-coenzyme A carboxylase alpha chain [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
BN406_05249  bhbA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
BN406_00434  glcD; Glycolate oxidase subunit glcD [KO:K00104] [EC:1.1.99.14]
BN406_06794  glcD; Glycolate oxidase subunit glcD [KO:K00104] [EC:1.1.99.14]
BN406_00435  glcE; glycolate oxidase subunit protein [KO:K11472] [EC:1.1.99.14]
BN406_06795  hypothetical protein [KO:K11472] [EC:1.1.99.14]
BN406_00436  hypothetical protein [KO:K11473] [EC:1.1.99.14]
BN406_06796  hypothetical protein [KO:K11473] [EC:1.1.99.14]
BN406_00421  katA; Catalase A [KO:K03781] [EC:1.11.1.6]
BN406_05126  katE; Catalase C [KO:K03781] [EC:1.11.1.6]
BN406_03304  gyaR3; Glyoxylate reductase [KO:K00015] [EC:1.1.1.26]
BN406_03285  hydroxyacid dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BN406_04755  hydroxypyruvate reductase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BN406_00467  hypothetical protein [KO:K01091] [EC:3.1.3.18]
BN406_01119  gph2; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
BN406_01591  gph; Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
BN406_06465  cbbL; Ribulose bisphosphate carboxylase large chain [KO:K01601] [EC:4.1.1.39]
BN406_06466  cbbS; ribulose-1,5-bisphosphate carboxylase small subunit protein [KO:K01602] [EC:4.1.1.39]
BN406_03708  aminotransferase, class V superfamily [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
BN406_04551  Agxt; Serine--pyruvate aminotransferase, mitochondrial [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
BN406_06798  sgaA; Serine--glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
BN406_00321  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
BN406_02037  hypothetical protein [KO:K01915] [EC:6.3.1.2]
BN406_02355  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
BN406_02429  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
BN406_01379  glnA; Glutamine synthetase 1 [KO:K01915] [EC:6.3.1.2]
BN406_05261  glnII; Glutamine synthetase 2 [KO:K01915] [EC:6.3.1.2]
BN406_00943  glyA1; Serine hydroxymethyltransferase 1 [KO:K00600] [EC:2.1.2.1]
BN406_01279  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
BN406_03233  aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
BN406_03238  aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
BN406_01281  gcvT; Aminomethyltransferase, mitochondrial [KO:K00605] [EC:2.1.2.10]
BN406_02792  lpdV; Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BN406_02904  LPD2; Dihydrolipoyl dehydrogenase 2, mitochondrial [KO:K00382] [EC:1.8.1.4]
BN406_01183  lpdA; Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BN406_06654  lpdA; Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BN406_01280  gcvH; glycine cleavage system protein H [KO:K02437]
BN406_05311  gcl; Glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
BN406_05312  hyi; Hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
BN406_05313  glxR; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
BN406_03905  hypothetical protein [KO:K00042] [EC:1.1.1.60]
BN406_04949  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
BN406_05314  ttuD; Putative hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
BN406_03090  ttuD; Putative hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
BN406_04503  ttuD; Putative hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
BN406_04758  ycsA; putative tartrate dehydrogenase/decarboxylase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
BN406_02740  eda; KHG/KDPG aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
BN406_02403  eda1; KHG/KDPG aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
BN406_03885  Formate dehydrogenase [KO:K00122] [EC:1.17.1.9]
BN406_03986  Formate dehydrogenase [KO:K00122] [EC:1.17.1.9]
BN406_02862  fdsD; NAD-dependent formate dehydrogenase delta subunit protein [KO:K00126] [EC:1.17.1.9]
BN406_02864  fdsA; NAD-dependent formate dehydrogenase alpha subunit protein [KO:K00123] [EC:1.17.1.9]
BN406_05086  fdoG1; Formate dehydrogenase-O major subunit [KO:K00123] [EC:1.17.1.9]
BN406_05087  fdoG3; Formate dehydrogenase-O major subunit [KO:K00123] [EC:1.17.1.9]
BN406_02866  fdsB; NAD-dependent formate dehydrogenase beta subunit protein [KO:K00124]
BN406_05085  fdoH; Formate dehydrogenase-O iron-sulfur subunit [KO:K00124]
BN406_02867  fdsG; formate dehydrogenase subunit gamma [KO:K00127]
BN406_05084  fdoI; formate dehydrogenase subunit gamma [KO:K00127]
BN406_04938  hypothetical protein [KO:K01432] [EC:3.5.1.9]
BN406_03232  purU3; Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BN406_02793  purU1; Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BN406_05827  N-formylglutamate amidohydrolase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
smi00010  Glycolysis / Gluconeogenesis
smi00020  Citrate cycle (TCA cycle)
smi00030  Pentose phosphate pathway
smi00053  Ascorbate and aldarate metabolism
smi00071  Fatty acid degradation
smi00230  Purine metabolism
smi00250  Alanine, aspartate and glutamate metabolism
smi00260  Glycine, serine and threonine metabolism
smi00620  Pyruvate metabolism
smi00710  Carbon fixation by Calvin cycle
smi00750  Vitamin B6 metabolism
smi00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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