KEGG   PATHWAY: snz00630
Entry
snz00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces nigra
Class
Metabolism; Carbohydrate metabolism
Pathway map
snz00630  Glyoxylate and dicarboxylate metabolism
snz00630

Module
snz_M00621  Glycine cleavage system [PATH:snz00630]
snz_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:snz00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces nigra [GN:snz]
Gene
DC008_19100  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DC008_27860  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
DC008_28015  malate synthase A [KO:K01638] [EC:2.3.3.9]
DC008_21435  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
DC008_12070  citrate synthase [KO:K01647] [EC:2.3.3.1]
DC008_15125  citrate synthase [KO:K01647] [EC:2.3.3.1]
DC008_26320  citrate synthase [KO:K01647] [EC:2.3.3.1]
DC008_26325  citrate synthase/methylcitrate synthase [KO:K01647] [EC:2.3.3.1]
DC008_26905  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
DC008_20105  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
DC008_24135  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
DC008_09960  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
DC008_13925  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
DC008_08460  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
DC008_02715  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
DC008_29510  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
DC008_24130  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
DC008_28370  protein meaA [KO:K14447] [EC:5.4.99.63]
DC008_21960  acetyl-/propionyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
DC008_13190  acetyl-/propionyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
DC008_21980  methylmalonyl-CoA carboxyltransferase [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
DC008_21975  acyl-CoA carboxylase subunit epsilon [KO:K27095]
DC008_28270  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
DC008_28275  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
DC008_21735  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
DC008_12895  FAD-binding oxidoreductase [KO:K00104] [EC:1.1.99.14]
DC008_23125  catalase [KO:K03781] [EC:1.11.1.6]
DC008_33350  catalase HPII [KO:K03781] [EC:1.11.1.6]
DC008_15335  haloacid dehalogenase [KO:K01091] [EC:3.1.3.18]
DC008_09375  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
DC008_09425  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
DC008_09555  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
DC008_06090  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
DC008_29865  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
DC008_21515  glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
DC008_23965  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
DC008_24510  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
DC008_04910  glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
DC008_24520  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
DC008_09290  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DC008_03425  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
DC008_24515  gcvH; glycine cleavage system protein GcvH [KO:K02437]
DC008_27880  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
DC008_27895  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
DC008_27890  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
DC008_28340  glycerate kinase [KO:K00865] [EC:2.7.1.165]
DC008_02210  aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
DC008_09795  keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
DC008_23470  kgd; multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
DC008_06485  formate dehydrogenase [KO:K00127]
DC008_15055  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
DC008_28875  frc; formyl-CoA transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
snz00010  Glycolysis / Gluconeogenesis
snz00020  Citrate cycle (TCA cycle)
snz00030  Pentose phosphate pathway
snz00053  Ascorbate and aldarate metabolism
snz00071  Fatty acid degradation
snz00230  Purine metabolism
snz00250  Alanine, aspartate and glutamate metabolism
snz00260  Glycine, serine and threonine metabolism
snz00620  Pyruvate metabolism
snz00710  Carbon fixation by Calvin cycle
snz00750  Vitamin B6 metabolism
snz00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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