Entry Name ABC transporters - Shewanella oneidensis
Description The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class Environmental Information Processing; Membrane transportBRITE hierarchy
Pathway map Ortholog table Other DBs Organism Shewanella oneidensis [GN:
son ]
Gene SO_3599 cysP; ABC-type sulfate/thiosulfate uptake system substrate-binding component CysP [KO:K02048 ]
SO_4652 sbp; ABC-type sulfate/thiosulfate uptakesystem substrate-binding subunit Sbp [KO:K23163 ]
SO_4653 cysT; ABC-type sulfate/thiosulfate uptakesystem permease component 1 CysT [KO:K02046 ]
SO_3600 cysT; ABC-type sulfate/thiosulfate uptake system permease component 1 CysT [KO:K02046 ]
SO_4654 cysW; ABC-type sulfate/thiosulfate uptakesystem permease component 2 CysW [KO:K02047 ]
SO_3601 cysW; ABC-type sulfate/thiosulfate uptake system permease component 2 CysW [KO:K02047 ]
SO_4655 cysA; ABC-type sulfate/thiosulfate uptakesystem ATPase component CysA [KO:K02045 ] [EC:7.3.2.3 ]
SO_3602 cysA; ABC-type sulfate/thiosulfate uptake system ATPase component CysA [KO:K02045 ] [EC:7.3.2.3 ]
SO_4719 tupA; ABC-type tungstate uptake system substrate-binding component TupA [KO:K05772 ]
SO_4720 tupB; ABC-type tungstate uptake system permease component TupB [KO:K05773 ]
SO_4448 modA; ABC-type molybdate uptake system substrate-binding component ModA [KO:K02020 ]
SO_3863 modA; ABC-type molybdate uptake system substrate-binding component ModA [KO:K02020 ]
SO_3967 orphan ABC-type transport system substrate-binding component [KO:K02020 ]
SO_4447 modB; ABC-type molybdate uptake system permease component ModB [KO:K02018 ]
SO_3864 modB; ABC-type molybdate uptake system permease component ModB [KO:K02018 ]
SO_0726 phrA; photoreactivation-associated protein PhrA [KO:K05776 ]
SO_0744 fbpA; ABC-type Fe3+ uptake system substrate-binding component FbpA [KO:K02012 ]
SO_0743 fbpB; ABC-type Fe3+ uptake system permease component FbpB [KO:K02011 ]
SO_1270 potF; ABC-type putrescine uptake system substrate-binding component PotF [KO:K11073 ]
SO_1273 potI; ABC-type putrescine uptake system permease component 2 PotI [KO:K11074 ]
SO_1272 potH; ABC-type putrescine uptake system permease component 1 PotH [KO:K11075 ]
SO_3951 mlaC; ABC-type phospholipid uptake (salvage) system periplasmic chaperone MlaC [KO:K07323 ]
SO_3952 mlaD; ABC-type phospholipid uptake (salvage) system substrate-binding component MlaD [KO:K02067 ]
SO_3953 mlaE; ABC-type phospholipid uptake (salvage) system permease component MlaE [KO:K02066 ]
SO_3950 mlaB; ABC-type phospholipid uptake (salvage) system anti-anti-sigma factor MlaB [KO:K07122 ]
SO_3954 mlaF; ABC-type phospholipid uptake (salvage) system ATPase component MlaF [KO:K02065 ]
SO_3714 ABC-type monosaccharide transport system substrate binding component [KO:K10439 ]
SO_1560 pstS; ABC-type phosphate uptake system substrate-binding component PstS [KO:K02040 ]
SO_4292 pstS; ABC-type phosphate uptake system substrate-binding component PstS [KO:K02040 ]
SO_1723 pstC; ABC-type high affinity phosphate uptake system permease component PstC [KO:K02037 ]
SO_4291 pstC; ABC-type phosphate uptake system permease component PstC [KO:K02037 ]
SO_1724 pstA; ABC-type high affinity phosphate uptake system permease component PstA [KO:K02038 ]
SO_4290 pstA; ABC-type phosphate uptake system permease component PstA [KO:K02038 ]
SO_1725 pstB; ABC-type high affinity phosphate uptake system ATPase component PstB [KO:K02036 ] [EC:7.3.2.1 ]
SO_4289 pstB; ABC-type phosphate uptake system permease ATPase component PstB [KO:K02036 ] [EC:7.3.2.1 ]
SO_1044 artI; ABC-type arginine uptakesystem substrate-binding component ArtI [KO:K23059 ]
SO_1043 artQ; ABC-type arginine uptakesystem permease component ArtQ [KO:K17077 ]
SO_1805 sapA; ABC-type peptide uptake system substrate-binding component SapA [KO:K19226 ]
SO_1804 sapB; ABC-type peptide uptake system permease component 1 SapB [KO:K19227 ]
SO_1803 sapC; ABC-type peptide uptake system permease component 2 SapC [KO:K19228 ]
SO_1802 sapD; ABC-type peptide uptake system ATPase component 1 SapD [KO:K19229 ]
SO_1801 sapF; ABC-type peptide uptake system ATPase component 2 SapF [KO:K19230 ]
SO_3709 btuF; ABC-type cobalamin uptake system substrate-binding component BtuF [KO:K06858 ]
SO_0069 natB; ABC-type sodium efflux system permease component NatB [KO:K09696 ]
SO_2257 lolE; ABC-type lipoprotein release system permease component LolE [KO:K09808 ]
SO_2259 lolC; ABC-type lipoprotein release system permease component LolC [KO:K09808 ]
SO_2258 lolD; ABC-type lipoprotein release system ATPase component LolD [KO:K09810 ] [EC:7.6.2.-]
SO_0260 ccmD; ABC-type heme export system CcmE-interacting component CcmD [KO:K02196 ]
SO_0261 ccmC; ABC-type heme export system permease component 2 CcmC [KO:K02195 ]
SO_0262 ccmB; ABC-type heme export system permease component 1 CcmB [KO:K02194 ]
SO_1369 lptF; ABC-type lipopolysaccharide export system permease component 1 LptF [KO:K07091 ]
SO_1370 lptG; ABC-type lipopolysaccharide export system permease component 2 LptG [KO:K11720 ]
SO_3960 lptB; ABC-type lipopolysaccharide export system ATPase component LptB [KO:K06861 ] [EC:7.5.2.5 ]
SO_0488 nosY; ABC-type copper transport system permease component NosY [KO:K19341 ]
SO_0487 nosF; ABC-type copper transport system ATPase component NosF [KO:K19340 ]
SO_4584 ftsX; ABC-type cell division-associated export system permease component FtsX [KO:K09811 ]
SO_4585 ftsE; ABC-type cell division-associated export system ATPase component FtsE [KO:K09812 ]
SO_2802 msbA; ABC-type lipid A export system bifunctional ATPase and permease components MsbA [KO:K11085 ] [EC:7.5.2.6 ]
SO_A0049 ABC-type bacteriocin export system multifunctional permease/ATPase/protease component [KO:K13409 ]
SO_0754 atmA; ABC-type Ni2+/Co2+ export system bifunctional ATPase and permease components AtmA [KO:K24821 ]
SO_3128 ABC-type metal export system bifunctional ATPase and permease component [KO:K18893 ]
SO_4318 aggC; type I protein secretion system bifunctional ATPase and permease component AggC [KO:K12541 ]
SO_4147 type I secretion system ATPase and inner membrane subunit HlyB family [KO:K12541 ]
SO_4146 type I secretion system ATPase subunit HlyB family [KO:K12541 ]
SO_3779 cydC; ABC-type cysteine/glutathione export system bifunctional ATPase and permease component CydC [KO:K16012 ]
SO_3780 cydD; ABC-type cysteine/glutathione export system bifunctional ATPase and permease components CydD [KO:K16013 ]
SO_0821 macB; ABC-type macrolide export system bifunctional ATPase and permease component MacB [KO:K05685 ] [EC:7.6.2.-]
Compound C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference Authors Tomii K, Kanehisa M.
Title A comparative analysis of ABC transporters in complete microbial genomes.
Journal Reference Authors Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal Reference Authors Quintero MJ, Montesinos ML, Herrero A, Flores E
Title Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal Reference Authors Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal Reference Authors Valladares A, Montesinos ML, Herrero A, Flores E.
Title An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal Reference Authors Richard-Fogal CL, Frawley ER, Kranz RG
Title Topology and function of CcmD in cytochrome c maturation.
Journal Reference Authors Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal Reference Authors Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal Reference Authors Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal Reference Authors Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal KO pathway LinkDB All DBs
