KEGG   PATHWAY: sti00630
Entry
sti00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Sphaerobacter thermophilus
Class
Metabolism; Carbohydrate metabolism
Pathway map
sti00630  Glyoxylate and dicarboxylate metabolism
sti00630

Module
sti_M00621  Glycine cleavage system [PATH:sti00630]
Other DBs
GO: 0046487 0043648
Organism
Sphaerobacter thermophilus [GN:sti]
Gene
Sthe_1581  acetate/CoA ligase [KO:K01895] [EC:6.2.1.1]
Sthe_2381  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
Sthe_3523  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
Sthe_2025  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
Sthe_2906  malate synthase A [KO:K01638] [EC:2.3.3.9]
Sthe_1112  malate dehydrogenase, NAD-dependent [KO:K00024] [EC:1.1.1.37]
Sthe_3481  2-methylcitrate synthase/citrate synthase II [KO:K01647] [EC:2.3.3.1]
Sthe_0650  2-methylcitrate synthase/citrate synthase II [KO:K01647] [EC:2.3.3.1]
Sthe_2772  aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
Sthe_0112  Thiolase [KO:K00626] [EC:2.3.1.9]
Sthe_2009  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
Sthe_2064  Citryl-CoA lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
Sthe_2003  acetyl-CoA carboxylase, biotin carboxylase [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
Sthe_1206  cobalamin B12-binding domain protein [KO:K01849] [EC:5.4.99.2]
Sthe_2008  methylmalonyl-CoA mutase, large subunit [KO:K01848] [EC:5.4.99.2]
Sthe_1205  methylmalonyl-CoA mutase, large subunit [KO:K01848] [EC:5.4.99.2]
Sthe_0985  FAD linked oxidase domain protein [KO:K00104] [EC:1.1.99.14]
Sthe_0986  FAD linked oxidase domain protein [KO:K11472] [EC:1.1.99.14]
Sthe_0987  protein of unknown function DUF224 cysteine-rich region domain protein [KO:K11473] [EC:1.1.99.14]
Sthe_1212  Glyoxylate reductase [KO:K00015] [EC:1.1.1.26]
Sthe_2645  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein [KO:K00015] [EC:1.1.1.26]
Sthe_0626  Haloacid dehalogenase domain protein hydrolase [KO:K01091] [EC:3.1.3.18]
Sthe_2420  Haloacid dehalogenase domain protein hydrolase [KO:K01091] [EC:3.1.3.18]
Sthe_2871  Glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
Sthe_2416  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
Sthe_2624  glutamine synthetase catalytic region [KO:K01915] [EC:6.3.1.2]
Sthe_1283  Glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Sthe_1285  Glycine dehydrogenase (decarboxylating) [KO:K00282] [EC:1.4.4.2]
Sthe_0897  Glycine dehydrogenase (decarboxylating) [KO:K00283] [EC:1.4.4.2]
Sthe_1287  glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
Sthe_3478  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Sthe_1286  glycine cleavage system H protein [KO:K02437]
Sthe_3355  6-phosphogluconate dehydrogenase NAD-binding protein [KO:K00042] [EC:1.1.1.60]
Sthe_0502  Hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
Sthe_3519  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
Sthe_0952  2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
Sthe_0488  Dihydrodipicolinate synthase [KO:K18123] [EC:4.1.3.16]
Sthe_1651  molybdopterin oxidoreductase [KO:K00123] [EC:1.17.1.9]
Sthe_2474  molybdopterin oxidoreductase Fe4S4 region [KO:K00123] [EC:1.17.1.9]
Sthe_2475  Nitrate reductase [KO:K00123] [EC:1.17.1.9]
Sthe_3388  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
Sthe_2476  4Fe-4S ferredoxin iron-sulfur binding domain protein [KO:K00124]
Sthe_3389  4Fe-4S ferredoxin iron-sulfur binding domain protein [KO:K00124]
Sthe_2468  Formamidase [KO:K01455] [EC:3.5.1.49]
Sthe_2487  Formamidase [KO:K01455] [EC:3.5.1.49]
Sthe_1570  Acetamidase/Formamidase [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
sti00010  Glycolysis / Gluconeogenesis
sti00020  Citrate cycle (TCA cycle)
sti00030  Pentose phosphate pathway
sti00053  Ascorbate and aldarate metabolism
sti00071  Fatty acid degradation
sti00230  Purine metabolism
sti00250  Alanine, aspartate and glutamate metabolism
sti00260  Glycine, serine and threonine metabolism
sti00620  Pyruvate metabolism
sti00710  Carbon fixation by Calvin cycle
sti00750  Vitamin B6 metabolism
sti00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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