KEGG   PATHWAY: strp00630
Entry
strp00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces sp. PAMC 26508
Class
Metabolism; Carbohydrate metabolism
Pathway map
strp00630  Glyoxylate and dicarboxylate metabolism
strp00630

Module
strp_M00621  Glycine cleavage system [PATH:strp00630]
strp_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:strp00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces sp. PAMC 26508 [GN:strp]
Gene
F750_0078  acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
F750_5774  acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
F750_3321  acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
F750_5810  malate synthase [KO:K01638] [EC:2.3.3.9]
F750_4388  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
F750_2541  citrate synthase [KO:K01647] [EC:2.3.3.1]
F750_5343  citrate synthase [KO:K01647] [EC:2.3.3.1]
F750_5344  citrate synthase [KO:K01647] [EC:2.3.3.1]
F750_4128  citrate synthase [KO:K01647] [EC:2.3.3.1]
F750_5581  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
F750_5711  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
F750_6188  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
F750_4896  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
F750_3102  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
F750_2910  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
F750_4895  methylmalonyl-CoA epimerase; Ethylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
F750_5948  ethylmalonyl-CoA mutase [KO:K14447] [EC:5.4.99.63]
F750_4468  biotin carboxylase of acetyl-CoA carboxylase / Biotin carboxyl carrier protein of acetyl-CoA carboxylase [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
F750_4473  acetyl-coenzyme A carboxyl transferase alpha chain / Acetyl-coenzyme A carboxyl transferase beta chain [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
F750_4472  hypothetical protein [KO:K27095]
F750_0592  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
F750_0593  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
F750_4417  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
F750_5852  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
F750_5863  putative glutamate mutase subumit E [KO:K19268] [EC:5.4.99.1]
F750_5862  glutamate mutase S-chain [KO:K01846] [EC:5.4.99.1]
F750_4781  glcD; glycolate dehydrogenase [KO:K00104] [EC:1.1.99.14]
F750_2751  lactate dehydrogenase [KO:K00104] [EC:1.1.99.14]
F750_0422  catalase [KO:K03781] [EC:1.11.1.6]
F750_5780  catalase [KO:K03781] [EC:1.11.1.6]
F750_5532  catalase [KO:K03781] [EC:1.11.1.6]
F750_4739  catalase [KO:K03781] [EC:1.11.1.6]
F750_4053  putative hydrolase [KO:K01091] [EC:3.1.3.18]
F750_1405  glutamine synthetase family protein in hypothetical Actinobacterial gene cluster [KO:K01915] [EC:6.3.1.2]
F750_2053  glutamine synthetase type I [KO:K01915] [EC:6.3.1.2]
F750_2063  glutamine synthetase type II [KO:K01915] [EC:6.3.1.2]
F750_2099  glutamine synthetase type I [KO:K01915] [EC:6.3.1.2]
F750_4864  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
F750_4961  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
F750_1121  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
F750_4963  aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
F750_2038  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
F750_4962  glycine cleavage system H protein [KO:K02437]
F750_5778  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
F750_5782  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
F750_5781  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
F750_5933  glycerate kinase [KO:K00865] [EC:2.7.1.165]
F750_2164  4-Hydroxy-2-oxoglutarate aldolase / 2-dehydro-3-deoxyphosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
F750_0915  4-Hydroxy-2-oxoglutarate aldolase / 2-dehydro-3-deoxyphosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
F750_4808  dihydrolipoamide succinyltransferase component (E2) [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
F750_0084  NAD-dependent formate dehydrogenase alpha subunit [KO:K00123] [EC:1.17.1.9]
F750_1488  formate dehydrogenase O gamma subunit [KO:K00127]
F750_4143  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
strp00010  Glycolysis / Gluconeogenesis
strp00020  Citrate cycle (TCA cycle)
strp00030  Pentose phosphate pathway
strp00053  Ascorbate and aldarate metabolism
strp00071  Fatty acid degradation
strp00230  Purine metabolism
strp00250  Alanine, aspartate and glutamate metabolism
strp00260  Glycine, serine and threonine metabolism
strp00620  Pyruvate metabolism
strp00710  Carbon fixation by Calvin cycle
strp00750  Vitamin B6 metabolism
strp00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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