KEGG   PATHWAY: tcu00630
Entry
tcu00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Thermomonospora curvata
Class
Metabolism; Carbohydrate metabolism
Pathway map
tcu00630  Glyoxylate and dicarboxylate metabolism
tcu00630

Module
tcu_M00012  Glyoxylate cycle [PATH:tcu00630]
tcu_M00621  Glycine cleavage system [PATH:tcu00630]
tcu_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:tcu00630]
Other DBs
GO: 0046487 0043648
Organism
Thermomonospora curvata [GN:tcu]
Gene
Tcur_2490  isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
Tcur_4841  acetate/CoA ligase [KO:K01895] [EC:6.2.1.1]
Tcur_0883  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
Tcur_3270  malate synthase A [KO:K01638] [EC:2.3.3.9]
Tcur_4209  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
Tcur_1964  citrate synthase I [KO:K01647] [EC:2.3.3.1]
Tcur_0834  Citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
Tcur_1749  aconitate hydratase 1 [KO:K27802] [EC:4.2.1.3 4.2.1.99]
Tcur_3474  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Tcur_3495  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Tcur_3981  Propanoyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
Tcur_1472  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Tcur_2713  Propanoyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
Tcur_1860  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Tcur_3654  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Tcur_3890  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Tcur_0842  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Tcur_1045  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Tcur_4616  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Tcur_3891  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
Tcur_4175  Carbamoyl-phosphate synthase L chain ATP-binding protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
Tcur_4130  carboxyl transferase [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
Tcur_4131  hypothetical protein [KO:K27095]
Tcur_1637  carboxyl transferase [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
Tcur_2505  methylmalonyl-CoA mutase, large subunit [KO:K01847] [EC:5.4.99.2]
Tcur_2506  Methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
Tcur_3271  D-lactate dehydrogenase (cytochrome) [KO:K00104] [EC:1.1.99.14]
Tcur_0108  FAD linked oxidase domain protein [KO:K00104] [EC:1.1.99.14]
Tcur_3272  FAD linked oxidase domain protein [KO:K11472] [EC:1.1.99.14]
Tcur_3273  protein of unknown function DUF224 cysteine-rich region domain protein [KO:K11473] [EC:1.1.99.14]
Tcur_2447  Catalase [KO:K03781] [EC:1.11.1.6]
Tcur_0817  Haloacid dehalogenase domain protein hydrolase [KO:K01091] [EC:3.1.3.18]
Tcur_0948  haloacid dehalogenase-like hydrolase [KO:K01091] [EC:3.1.3.18]
Tcur_4015  Haloacid dehalogenase domain protein hydrolase [KO:K01091] [EC:3.1.3.18]
Tcur_1655  Ribulose-bisphosphate carboxylase [KO:K01601] [EC:4.1.1.39]
Tcur_1656  Ribulose-bisphosphate carboxylase [KO:K01602] [EC:4.1.1.39]
Tcur_3102  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
Tcur_3106  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
Tcur_3351  Glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Tcur_3847  Glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Tcur_2429  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
Tcur_3845  glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
Tcur_3092  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Tcur_3815  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Tcur_3846  glycine cleavage system H protein [KO:K02437]
Tcur_3130  glycerate kinase [KO:K00865] [EC:2.7.1.165]
Tcur_1744  2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
Tcur_3675  2-oxoglutarate dehydrogenase, E1 subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
Tcur_3853  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Tcur_3454  formamidase [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
tcu00010  Glycolysis / Gluconeogenesis
tcu00020  Citrate cycle (TCA cycle)
tcu00030  Pentose phosphate pathway
tcu00053  Ascorbate and aldarate metabolism
tcu00071  Fatty acid degradation
tcu00230  Purine metabolism
tcu00250  Alanine, aspartate and glutamate metabolism
tcu00260  Glycine, serine and threonine metabolism
tcu00620  Pyruvate metabolism
tcu00710  Carbon fixation by Calvin cycle
tcu00750  Vitamin B6 metabolism
tcu00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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