KEGG   PATHWAY: thk00630
Entry
thk00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Thauera sp. K11
Class
Metabolism; Carbohydrate metabolism
Pathway map
thk00630  Glyoxylate and dicarboxylate metabolism
thk00630

Module
thk_M00012  Glyoxylate cycle [PATH:thk00630]
thk_M00621  Glycine cleavage system [PATH:thk00630]
Other DBs
GO: 0046487 0043648
Organism
Thauera sp. K11 [GN:thk]
Gene
CCZ27_13075  isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
CCZ27_01710  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
CCZ27_11050  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
CCZ27_12935  malate synthase A [KO:K01638] [EC:2.3.3.9]
CCZ27_06420  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
CCZ27_06455  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
CCZ27_07415  2-methylcitrate synthase [KO:K01659] [EC:2.3.3.5]
CCZ27_09670  acnA; aconitate hydratase AcnA [KO:K27802] [EC:4.2.1.3 4.2.1.99]
CCZ27_06350  acnB; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
CCZ27_16615  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
CCZ27_16705  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
CCZ27_17830  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
CCZ27_11085  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
CCZ27_15620  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
CCZ27_04120  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
CCZ27_04125  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
CCZ27_03160  (R)-hydratase [KO:K17865] [EC:4.2.1.55]
CCZ27_14800  accC; acetyl-CoA carboxylase biotin carboxylase subunit [KO:K01965] [EC:6.4.1.3]
CCZ27_14805  methylmalonyl-CoA carboxyltransferase [KO:K01966] [EC:6.4.1.3 2.1.3.15]
CCZ27_14815  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
CCZ27_03385  FAD-binding oxidoreductase [KO:K00104] [EC:1.1.99.14]
CCZ27_03395  glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
CCZ27_03400  glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
CCZ27_02360  catalase [KO:K03781] [EC:1.11.1.6]
CCZ27_11835  haloacid dehalogenase [KO:K01091] [EC:3.1.3.18]
CCZ27_07175  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
CCZ27_00935  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
CCZ27_13875  rbcL; ribulose-bisphosphate carboxylase large subunit [KO:K01601] [EC:4.1.1.39]
CCZ27_13880  ribulose bisphosphate carboxylase small subunit [KO:K01602] [EC:4.1.1.39]
CCZ27_15765  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CCZ27_13670  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
CCZ27_12055  gcvP; glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
CCZ27_06230  gcvT; glycine cleavage system protein T [KO:K00605] [EC:2.1.2.10]
CCZ27_12020  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
CCZ27_18725  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
CCZ27_06470  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
CCZ27_12050  gcvH; glycine cleavage system protein H [KO:K02437]
CCZ27_20420  hypothetical protein [KO:K02437]
CCZ27_15370  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
CCZ27_15375  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
CCZ27_14310  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
CCZ27_15380  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
CCZ27_14315  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
CCZ27_15390  glycerate kinase [KO:K11529] [EC:2.7.1.165]
CCZ27_17510  formate dehydrogenase [KO:K00126] [EC:1.17.1.9]
CCZ27_20390  sulfate ABC transporter substrate-binding protein [KO:K00123] [EC:1.17.1.9]
CCZ27_20395  fdnG; formate dehydrogenase-N subunit alpha [KO:K00123] [EC:1.17.1.9]
CCZ27_17500  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
CCZ27_20400  fdxH; formate dehydrogenase subunit beta [KO:K00124]
CCZ27_17495  formate dehydrogenase [KO:K00124]
CCZ27_20405  formate dehydrogenase subunit gamma [KO:K00127]
CCZ27_17490  formate dehydrogenase [KO:K00127]
CCZ27_17455  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
thk00010  Glycolysis / Gluconeogenesis
thk00020  Citrate cycle (TCA cycle)
thk00030  Pentose phosphate pathway
thk00053  Ascorbate and aldarate metabolism
thk00071  Fatty acid degradation
thk00230  Purine metabolism
thk00250  Alanine, aspartate and glutamate metabolism
thk00260  Glycine, serine and threonine metabolism
thk00620  Pyruvate metabolism
thk00710  Carbon fixation by Calvin cycle
thk00750  Vitamin B6 metabolism
thk00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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