KEGG   PATHWAY: pti04148
Entry
pti04148                    Pathway                                
Name
Efferocytosis - Phaeodactylum tricornutum
Class
Cellular Processes; Transport and catabolism
Pathway map
pti04148  Efferocytosis
pti04148

Organism
Phaeodactylum tricornutum [GN:pti]
Gene
PHATRDRAFT_12233  [KO:K00411] [EC:7.1.1.8]
PHATRDRAFT_12642  ODC2; ornithine decarboxylase 2 [KO:K01581] [EC:4.1.1.17]
PHATRDRAFT_14453  hCDK7; hypothetical protein [KO:K04371] [EC:2.7.11.24]
PHATRDRAFT_30620  [KO:K07299]
PHATRDRAFT_38509  [KO:K01476] [EC:3.5.3.1]
PHATRDRAFT_41172  [KO:K08057]
PHATRDRAFT_42975  [KO:K20182]
PHATRDRAFT_43038  [KO:K20179]
PHATRDRAFT_43103  [KO:K20178]
PHATRDRAFT_44806  [KO:K04718] [EC:2.7.1.91]
PHATRDRAFT_45223  [KO:K26935]
PHATRDRAFT_45316  [KO:K20184]
PHATRDRAFT_46588  [KO:K20183]
PHATRDRAFT_47275  [KO:K20180]
PHATRDRAFT_51199  Rab7; hypothetical protein [KO:K07897]
PHATRDRAFT_51511  Rab5a; hypothetical protein [KO:K07889]
PHATRDRAFT_52368  ATPase-P4; P4, P type ATPase [KO:K14802] [EC:7.6.2.1]
PHATR_44037  [KO:K20181]
Compound
C00002  ATP
C00003  NAD+
C00019  S-Adenosyl-L-methionine
C00031  D-Glucose
C00062  L-Arginine
C00073  L-Methionine
C00075  UTP
C00077  L-Ornithine
C00134  Putrescine
C00162  Fatty acid
C00186  (S)-Lactate
C00187  Cholesterol
C00584  Prostaglandin E2
C02530  Cholesterol ester
C02737  Phosphatidylserine
C04230  1-Acyl-sn-glycero-3-phosphocholine
C06124  Sphingosine 1-phosphate
C06314  Lipoxin A4
C15519  25-Hydroxycholesterol
C15610  Cholest-5-ene-3beta,26-diol
C18178  Resolvin D1
Reference
PMID:31822793
  Authors
Doran AC, Yurdagul A Jr, Tabas I
  Title
Efferocytosis in health and disease.
  Journal
Nat Rev Immunol 20:254-267 (2020)
DOI:10.1038/s41577-019-0240-6
Reference
PMID:36028471
  Authors
Zhang J, Ding W, Zhao M, Liu J, Xu Y, Wan J, Wang M
  Title
Mechanisms of efferocytosis in determining inflammation resolution: Therapeutic potential and the association with cardiovascular disease.
  Journal
Br J Pharmacol 179:5151-5171 (2022)
DOI:10.1111/bph.15939
Reference
PMID:30165442
  Authors
Kawano M, Nagata S
  Title
Efferocytosis and autoimmune disease.
  Journal
Int Immunol 30:551-558 (2018)
DOI:10.1093/intimm/dxy055
Reference
PMID:35650427
  Authors
Mehrotra P, Ravichandran KS
  Title
Drugging the efferocytosis process: concepts and opportunities.
  Journal
Nat Rev Drug Discov 21:601-620 (2022)
DOI:10.1038/s41573-022-00470-y
Reference
PMID:28496201
  Authors
Park SY, Kim IS
  Title
Engulfment signals and the phagocytic machinery for apoptotic cell clearance.
  Journal
Exp Mol Med 49:e331 (2017)
DOI:10.1038/emm.2017.52
Reference
PMID:28137963
  Authors
Kojima Y, Weissman IL, Leeper NJ
  Title
The Role of Efferocytosis in Atherosclerosis.
  Journal
Circulation 135:476-489 (2017)
DOI:10.1161/CIRCULATIONAHA.116.025684
Related
pathway
pti00010  Glycolysis / Gluconeogenesis
pti04145  Phagosome
KO pathway
ko04148   

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