KEGG   PATHWAY: shy00630
Entry
shy00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces hygroscopicus subsp. jinggangensis 5008
Class
Metabolism; Carbohydrate metabolism
Pathway map
shy00630  Glyoxylate and dicarboxylate metabolism
shy00630

Module
shy_M00621  Glycine cleavage system [PATH:shy00630]
shy_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:shy00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces hygroscopicus subsp. jinggangensis 5008 [GN:shy]
Gene
SHJG_8767  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
SHJG_5448  putative acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
SHJG_2438  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
SHJG_7257  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
SHJG_7291  malate synthase [KO:K01638] [EC:2.3.3.9]
SHJG_5950  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
SHJG_4755  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
SHJG_4239  type II citrate synthase [KO:K01647] [EC:2.3.3.1]
SHJG_6937  citrate synthase [KO:K01647] [EC:2.3.3.1]
SHJG_6938  citrate synthase [KO:K01647] [EC:2.3.3.1]
SHJG_7070  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
SHJG_6479  thiolase FadA [KO:K00626] [EC:2.3.1.9]
SHJG_4552  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SHJG_7625  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SHJG_3829  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SHJG_3498  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SHJG_6478  hypothetical protein [KO:K05606] [EC:5.1.99.1]
SHJG_7433  coenzyme B12-dependent mutase [KO:K14447] [EC:5.4.99.63]
SHJG_6035  acyl-CoA carboxylase complex A subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
SHJG_6040  propionyl-CoA carboxylase complex B subunit [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
SHJG_6039  hypothetical protein [KO:K27095]
SHJG_7009  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
SHJG_7010  methylmalonyl-CoA mutase, beta subunit [KO:K01847] [EC:5.4.99.2]
SHJG_5992  methylmalonyll-CoA mutase [KO:K01848] [EC:5.4.99.2]
SHJG_1909  glutamate mutase E-chain [KO:K19268] [EC:5.4.99.1]
SHJG_1664  glutamate mutase E-chain [KO:K19268] [EC:5.4.99.1]
SHJG_1910  glutamate mutase S-chain [KO:K01846] [EC:5.4.99.1]
SHJG_1663  glutamate mutase S-chain [KO:K01846] [EC:5.4.99.1]
SHJG_4403  (S)-2-hydroxy-acid oxidase [KO:K00104] [EC:1.1.99.14]
SHJG_6316  bromoperoxidase-catalase [KO:K03781] [EC:1.11.1.6]
SHJG_0439  catalase [KO:K03781] [EC:1.11.1.6]
SHJG_7264  catalase [KO:K03781] [EC:1.11.1.6]
SHJG_7984  putative catalase [KO:K03781] [EC:1.11.1.6]
SHJG_8248  catalase [KO:K03781] [EC:1.11.1.6]
SHJG_4802  hydrolase [KO:K01091] [EC:3.1.3.18]
SHJG_0577  hydrolase [KO:K01091] [EC:3.1.3.18]
SHJG_7685  putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
SHJG_1789  L-glutamine synthetase [KO:K01915] [EC:6.3.1.2]
SHJG_3687  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
SHJG_3049  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
SHJG_3702  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
SHJG_3730  putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
SHJG_5966  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SHJG_6445  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SHJG_6559  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SHJG_1843  putative glycine/serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SHJG_2796  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
SHJG_6561  glycine cleavage system aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
SHJG_0780  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
SHJG_3659  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
SHJG_2462  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
SHJG_7157  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
SHJG_6560  glycine cleavage system H protein [KO:K02437]
SHJG_7260  glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
SHJG_7266  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
SHJG_8485  xylose isomerase domain protein TIM barrel [KO:K01816] [EC:5.3.1.22]
SHJG_7265  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
SHJG_7427  glycerate kinase [KO:K00865] [EC:2.7.1.165]
SHJG_0241  aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
SHJG_8431  aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
SHJG_3788  2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
SHJG_6389  alpha-ketoglutarate decarboxylase [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
SHJG_2014  molybdopterin oxidoreductase Fe4S4 region [KO:K00123] [EC:1.17.1.9]
SHJG_2015  formate dehydrogenase alpha subunit [KO:K00123] [EC:1.17.1.9]
SHJG_2010  4Fe-4S ferredoxin, iron-sulfur binding protein [KO:K00124]
SHJG_0355  putative formate dehydrogenase [KO:K00127]
SHJG_3127  hypothetical protein [KO:K00127]
SHJG_4742  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
SHJG_1723  formamidase [KO:K01455] [EC:3.5.1.49]
SHJG_1066  acyl-CoA synthetase [KO:K22133] [EC:6.2.1.8]
SHJG_1065  putative oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
shy00010  Glycolysis / Gluconeogenesis
shy00020  Citrate cycle (TCA cycle)
shy00030  Pentose phosphate pathway
shy00053  Ascorbate and aldarate metabolism
shy00071  Fatty acid degradation
shy00230  Purine metabolism
shy00250  Alanine, aspartate and glutamate metabolism
shy00260  Glycine, serine and threonine metabolism
shy00620  Pyruvate metabolism
shy00710  Carbon fixation by Calvin cycle
shy00750  Vitamin B6 metabolism
shy00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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