 Mitochondrial DNA transcription, translation, and replication factors
|
|
Mitochondrial protein import machinery
|
|
 Mitochondrial quality control factors
|
Regulator of mitochondrial biogenesis
|
Ubiquitas transcription factors
|
Nuclear respiratory factors
|
 K11831 NRF1; nuclear respiratory factor 1
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K14739 MT1_2; metallothionein 1/2
K14740 MT3; metallothionein 3
K14741 MT4; metallothionein 4
|
Coactivators
|
K07202 PPARGC1A, PGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K17962 PPARGC1B, PGC1B; peroxisome proliferator-activated receptor gamma coactivator 1-beta
K17963 PPRC1, PRC; peroxisome proliferator-activated receptor gamma coactivator-related protein 1
K15309 CRTC1, TORC1; CREB-regulated transcription coactivator 1
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
|
Proteins involved in Fe-S cluster biogenesis
|
Other regulator of mitochondrial biogenesis
|
K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K19524 CPT1C; carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
K15791 DHKTD1; 2-oxoadipate dehydrogenase E1 component [EC:1.2.4.-]
K10270 FBXL4; F-box and leucine-rich repeat protein 4
K14966 HCFC1; host cell factor 1
K27390 HCFC2; host cell factor 2
K04533 HD; huntingtin
K08552 NR3B1, ESRRA; estrogen-related receptor alpha
K08553 NR3B2, ESRRB; estrogen-related receptor beta
K08554 NR3B3, ESRRG; estrogen-related receptor gamma
K17965 NRIP1; nuclear receptor-interacting protein 1
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K08675 LONP1, PRSS15, PIM1; ATP-dependent Lon protease [EC:3.4.21.53]
K11411 SIRT1, SIR2L1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K23504 SERAC1; protein SERAC1
K26537 UXT; protein UXT
K26738 PERM1; PGC-1 and ERR-induced regulator in muscle protein 1
K27835 GATD3, ES1; glutamine amidotransferase-like class 1 domain-containing protein 3, mitochondrial
K28098 TANGO2; transport and Golgi organization protein 2
K28271 C2ORF69; mitochondrial protein C2orf69
K28528 ATOS, FAM214; protein Atossa
K14777 DDX47, RRP3; ATP-dependent RNA helicase DDX47/RRP3 [EC:5.6.2.7]
K28918 PRR16; protein Largen
K29035 MTLN; mitoregulin
K18158 NCA2; nuclear control of ATPase protein 2
|
Mitochondrial respiratory chain complex assembly factors
|
Mitochondrial dynamics
|
Fission and Fusion factors
|
K21356 MFN1; mitofusin 1 [EC:3.6.5.-]
K06030 MFN2, FZO1; mitofusin 2 [EC:3.6.5.-]
K22140 MGM1; dynamin-like GTPase MGM1, mitochondrial
K17967 UGO1; mitochondrial fusion and transport protein UGO1
K17079 OPA1; optic atrophy protein 1 [EC:3.6.5.5]
K23166 OPA3; optic atrophy 3 protein
K15070 MDM30; mitochondrial distribution and morphology protein 30
K17968 TRIAP1, MDM35; TRIAP1/MDM35 family protein
K09650 PARL, PSARL, PCP1; rhomboid-like protein [EC:3.4.21.105]
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K02159 BAX; apoptosis regulator BAX
K17065 DNM1L, DNM1; dynamin 1-like protein [EC:3.6.5.5]
K17969 FIS1, TTC11, MDV2; mitochondrial fission 1 protein
K17970 MDV1, FIS2; mitochondrial division protein 1
K12160 SUMO, SMT3; small ubiquitin-related modifier
K11248 SH3GLB1; endophilin-B1
K17885 MTCH; mitochondrial carrier
K22076 MFF; mitochondrial fission factor
K22077 GDAP1; ganglioside-induced differentiation-associated protein 1
K23167 VAT1; synaptic vesicle membrane protein VAT-1 [EC:1.6.5.5]
K23507 MIEF1_2; mitochondrial dynamics protein MID51/49
K16862 PLD6; mitochondrial cardiolipin hydrolase [EC:3.1.4.-]
K27289 MIGA, FAM73; mitoguardin
K27836 ELM1; mitochondrial fission protein ELM1
|
Actin cytoskeleton organization
|
K05692 ACTB_G1; actin beta/gamma 1
K11238 BNI1; cytokinesis protein
K17971 BNR1; BNI1-related protein 1
K17945 TPM1_2; tropomyosin, fungi type
K17972 NAA20, NAT3; N-terminal acetyltransferase B complex catalytic subunit [EC:2.3.1.254]
K17973 NAA25, MDM20; N-terminal acetyltransferase B complex non-catalytic subunit
|
Mitochondrial movement
|
Retention of mitochondria
|
K17976 MMR1; mitochondrial MYO2 receptor-related protein 1
K17065 DNM1L, DNM1; dynamin 1-like protein [EC:3.6.5.5]
K17977 YPT11; GTP-binding protein YPT11
K10357 MYO5; myosin V
K17978 NUM1; nuclear migration protein NUM1
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K10522 DIABLO, SMAC; diablo
K28104 MME1; mitochondrial magnesium exporter 1
K28103 MME1; mitochondrial magnesium exporter 1
|
Morphogenesis factors
|
Mitophagy factors
|
Autophagy-related proteins
|
K17906 ATG2; autophagy-related protein 2
K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
K08339 ATG5; autophagy-related protein 5
K08334 BECN, VPS30, ATG6; beclin
K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
K08341 GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
K17907 ATG9; autophagy-related protein 9
K08338 ATG10; ubiquitin-like-conjugating enzyme ATG10
K17888 ATG10L, ATG10; ubiquitin-like-conjugating enzyme ATG10
K08330 ATG11; autophagy-related protein 11
K08336 ATG12; ubiquitin-like protein ATG12
K08335 ATG14; autophagy-related protein 14
K17889 ATG14L, ATG14; beclin 1-associated autophagy-related key regulator
K17900 ATG15, AUT5; lipase ATG15 [EC:3.1.1.3]
K08340 ATG16; autophagy-related protein 16
K17890 ATG16L1; autophagy-related protein 16-1
K20868 ATG16L2; autophagy-related protein 16-2
K08329 ATG17; autophagy-related protein 17
K17908 WIPI1_2, ATG18; autophagy-related protein 18
K17984 ATG32; autophagy-related protein 32
K28529 ATG44; mitofissin
K08332 VAC8; vacuolar protein 8
|
Parkin-dependent mechanism factors
|
Parkin-independent mechanism factors
|
K08331 ATG13; autophagy-related protein 13
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
K08269 ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
K17589 RB1CC1; RB1-inducible coiled-coil protein 1
K04079 HSP90A, htpG; molecular chaperone HtpG
K09554 CDC37; cell division cycle protein 37
K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
K15465 BNIP3L; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
K17986 FUNDC1; FUN14 domain-containing protein 1
|
Other mitophagy factors
|
Mitochondrial Biogenesis