[ Network menu | Network entry | Help ]

ENTRY	nt06543
Name	NRG-ERBB signaling
Category	Pathway view; Signal transduction
Pathway	hsa04012 ErbB signaling pathway
Disease	H00014 Non-small cell lung cancer H00019 Pancreatic cancer
Display	drug-target relation   disease type

D1  |   D1  |                         N01874    NRG − ERBB3 − ERBB2 → (SHC+GRB2) → SOS → RAS → RAF → MEK → ERK       D1  |   D1  |                 N01875    NRG − ERBB3 − ERBB2 → PI3K → PIP3 → AKT → MTOR       D1  | N01876    NSCLC/PDA NRG1*↗ − ERBB3 N01163    NRG → ERBB4 → PI3K → PIP3 → AKT N01877    ALS19 NRG ⌿ ERBB4*

		Disease name	Disease category
NSCLC/PDA	H00014	Non-small cell lung cancer	Cancer
	H00019	Pancreatic cancer	Cancer
ALS19	H00058	Amyotrophic lateral sclerosis (ALS)	Neurodegenerative disease

		Drug name
D1	D11991	Zenocutuzumab (USAN/INN)