Homo sapiens (human): 3767
Help
Entry
3767 CDS
T01001
Symbol
KCNJ11, BIR, HHF2, IKATP, KIR6.2, MODY13, PHHI, PNDM2, TNDM3
Name
(RefSeq) potassium inwardly rectifying channel subfamily J member 11
KO
K05004
potassium inwardly-rectifying channel subfamily J member 11
Organism
hsa
Homo sapiens (human)
Pathway
hsa04911
Insulin secretion
hsa04929
GnRH secretion
hsa04930
Type II diabetes mellitus
Disease
H00409
Type 2 diabetes mellitus
H00410
Maturity onset diabetes of the young (MODY)
H00512
Permanent neonatal diabetes mellitus
H00513
Transient neonatal diabetes mellitus
H01267
Familial hyperinsulinemic hypoglycemia
Drug target
Amiodarone (
DG00204
):
D00636
<JP/US>
D02910
Bepridil (
DG00333
):
D00631
<JP>
D07520
Chlorpropamide:
D00271
<JP>
Diazoxide:
D00294
<JP/US>
Dronedarone (
DG00207
):
D03914
<US>
Glibenclamide:
D00336
<JP/US>
Glymidine:
D01356
Levcromakalim:
D02385
D02385
Linogliride (
DG02893
):
D04739
D04740
Minoxidil:
D00418
<US>
Mitiglinide:
D01854
<JP>
Naminidil:
D05114
D05114
Nateglinide:
D01111
<JP/US>
Nicorandil:
D01810
<JP>
D01810
<JP>
Pinacidil:
D05482
D05482
Repaglinide:
D00594
<JP/US>
Tolazamide:
D00379
Tolbutamide (
DG00115
):
D00380
D06177
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
3767 (KCNJ11)
04929 GnRH secretion
3767 (KCNJ11)
09160 Human Diseases
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
3767 (KCNJ11)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hsa04040
]
3767 (KCNJ11)
Ion channels [BR:
hsa04040
]
Voltage-gated cation channels
Potassium channel, inwardly-rectifying (Kir)
3767 (KCNJ11)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
IRK_C
IRK
Ion_trans_2
Cupin_2
Motif
Other DBs
NCBI-GeneID:
3767
NCBI-ProteinID:
NP_001159762
OMIM:
600937
HGNC:
6257
Ensembl:
ENSG00000187486
Pharos:
Q14654
(Tclin)
UniProt:
Q14654
A0A804HHV7
Structure
PDB
LinkDB
All DBs
Position
11:complement(17385248..17389346)
Genome browser
AA seq
303 aa
AA seq
DB search
MAWWLIAFAHGDLAPSEGTAEPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAIL
ILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLRK
SMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSPL
YDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYS
VDYSKFGNTVKVPTPLCTARQLDEDHSLLEALTLASARGPLRKRSVPMAKAKPKFSISPD
SLS
NT seq
912 nt
NT seq
+upstream
nt +downstream
nt
atggcctggtggctcatcgccttcgcccacggtgacctggcccccagcgagggcactgct
gagccctgtgtcaccagcatccactccttctcgtctgccttccttttctccattgaggtc
caagtgactattggctttggggggcgcatggtgactgaggagtgcccactggccatcctg
atcctcatcgtgcagaacatcgtggggctcatgatcaacgccatcatgcttggctgcatc
ttcatgaagactgcccaagcccaccgcagggctgagaccctcatcttcagcaagcatgcg
gtgatcgccctgcgccacggccgcctctgcttcatgctacgtgtgggtgacctccgcaag
agcatgatcatcagcgccaccatccacatgcaggtggtacgcaagaccaccagccccgag
ggcgaggtggtgcccctccaccaggtggacatccccatggagaacggcgtgggtggcaac
agcatcttcctggtggccccgctgatcatctaccatgtcattgatgccaacagcccactc
tacgacctggcacccagcgacctgcaccaccaccaggacctcgagatcatcgtcatcctg
gaaggcgtggtggaaaccacgggcatcaccacccaggcccgcacctcctacctggccgat
gagatcctgtggggccagcgctttgtgcccattgtagctgaggaggacggacgttactct
gtggactactccaagtttggcaacaccgtcaaagtgcccacaccactctgcacggcccgc
cagcttgatgaggaccacagcctactggaagctctgaccctcgcctcagcccgcgggccc
ctgcgcaagcgcagcgtgcccatggccaaggccaagcccaagttcagcatctctccagat
tccctgtcctga
DBGET
integrated database retrieval system
