| Entry |
|
|---|
| Name |
Nicotine (USP);
Habitrol (TN) |
|---|
| Product |
|
|---|
| Formula |
C10H14N2
|
|---|
| Exact mass |
162.1157
|
|---|
| Mol weight |
162.2316
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Other
DG01718 Drugs for addictive disorder
DG01715 Drugs for nicotine dependence
Metabolizing enzyme substrate
DG01638 CYP2A6 substrate
Metabolizing enzyme inducer
DG01637 CYP1A2 inducer
|
|---|
| Remark |
| Therapeutic category: | 7990 |
| Product (DG00994): | D03365<JP/US> |
|
|---|
| Efficacy |
Smoking cessation adjunct |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Metabolism |
Enzyme: CYP2A6 [HSA: 1548]
|
|---|
| Interaction |
CYP induction: CYP1A2 [HSA: 1544]
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N07 OTHER NERVOUS SYSTEM DRUGS
N07B DRUGS USED IN ADDICTIVE DISORDERS
N07BA Drugs used in nicotine dependence
N07BA01 Nicotine
D03365 Nicotine (USP) <JP/US>
USP drug classification [BR:br08302]
Anti-Addiction/Substance Abuse Treatment Agents
Smoking Cessation Agents
Nicotine
D03365 Nicotine (USP)
Therapeutic category of drugs in Japan [BR:br08301]
7 Agents not mainly for therapeutic purpose
79 Other agents not mainly for therapeutic purpose
799 Miscellaneous
7990 Miscellaneous
D03365 Nicotine (USP)
Classification of Japanese OTC drugs [BR:br08313]
Stop smoking aid
77 Stop smoking aid
D03365 Nicotine (USP)
Risk category of Japanese OTC drugs [BR:br08312]
First-class OTC drugs
Inorganic and organic chemicals
Nicotine
D03365 Nicotine (USP)
Designated second-class OTC drugs
Inorganic and organic chemicals
Nicotine
D03365 Nicotine (USP)
Second-class OTC drugs
Inorganic and organic chemicals
Nicotine
D03365 Nicotine (USP)
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Acetylcholine (nicotinic)
CHRN
D03365 Nicotine (USP) <JP/US>
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D03365
Rx-to-OTC switch list in the USA [br08315.html]
D03365
Rx-to-OTC switch list in Japan [br08314.html]
D03365
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 12
1 C8x C 29.1341 -17.6496
2 C8x C 29.1341 -19.0503
3 N5x N 30.3471 -19.7507
4 C8x C 31.5602 -19.0503
5 C8y C 31.5602 -17.6496
6 C8x C 30.3471 -16.9493
7 C1y C 32.7920 -16.9383
8 C1x C 34.1270 -17.3204
9 C1x C 34.9074 -16.1695
10 C1x C 34.0540 -15.0718
11 N1y N 32.7463 -15.5441
12 C1a C 31.5702 -14.7465
BOND 13
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 7 5 1 #Up
8 7 8 1
9 8 9 1
10 9 10 1
11 10 11 1
12 7 11 1
13 11 12 1
|
|---|
