KEGG   DRUG: FenfluramineHelp
Entry
D07945                      Drug                                   

Name
Fenfluramine (INN);
Ponderax (TN)
Formula
C12H16F3N
Exact mass
231.1235
Mol weight
231.2574
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Other
 DG01706  Antiobesity
  DG01705  Anoretic
   DG01704  Phenethylamine anorexic
Remark
Same as: C06996
ATC code: A08AA02
Chemical structure group: DG00103
Efficacy
Appetite suppressant
Target
SLC6A4 (HTT) [HSA:6532] [KO:K05037]
HTR2 [HSA:3356 3357 3358] [KO:K04157]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04726  Serotonergic synapse
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A08 ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
   A08A ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
    A08AA Centrally acting antiobesity products
     A08AA02 Fenfluramine
      D07945  Fenfluramine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Serotonin
    HTR2
     D07945  Fenfluramine (INN)
 Transporters
  Solute carrier family
   SLC6
    SLC6A4 (HTT)
     D07945  Fenfluramine (INN)
BRITE hierarchy
Other DBs
CAS: 458-24-2
PubChem: 96024640
ChEBI: 5000
ChEMBL: CHEMBL87493
DrugBank: DB00547
LigandBox: D07945
NIKKAJI: J5.760F
LinkDB All DBs
KCF data Show

ATOM        16
            1   C8y C    18.1300  -16.0300
            2   C8x C    16.8700  -15.3300
            3   C8x C    18.1300  -17.4300
            4   C1b C    19.3200  -15.3300
            5   C8y C    15.6100  -16.0300
            6   C8x C    16.8700  -18.1300
            7   C1c C    20.5800  -16.0300
            8   C8x C    15.6100  -17.4300
            9   C1d C    14.4200  -15.3300
            10  N1b N    21.7700  -15.3300
            11  C1a C    20.5800  -17.4300
            12  X   F    13.0900  -14.5600
            13  X   F    13.7900  -16.3800
            14  X   F    15.1900  -14.2100
            15  C1b C    23.0300  -16.0300
            16  C1a C    24.2200  -15.3300
BOND        16
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     3   6 2
            6     4   7 1
            7     5   8 2
            8     5   9 1
            9     7  10 1
            10    7  11 1
            11    9  12 1
            12    9  13 1
            13    9  14 1
            14   10  15 1
            15   15  16 1
            16    6   8 1

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