| Entry |
|
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| Name |
Desvenlafaxine succinate anhydrous |
|---|
| Formula |
C16H25NO2. C4H6O4
|
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| Exact mass |
381.2151
|
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| Mol weight |
381.46
|
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| Structure |
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| Class |
Neuropsychiatric agent
DG01658 Serotonin and norepinephrine reuptake inhibitor (SNRI)
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG02924 UGT substrate
|
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| Remark |
| Product (DG00963): | D07793<US> D02570<US> |
|
|---|
| Efficacy |
Antidepressant, Serotonin-noradrenaline reuptake inhibitor (SNRI) |
|---|
| Disease |
Major depressive disorder [DS: H01646] |
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| Target |
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| Pathway |
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| Metabolism |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06A ANTIDEPRESSANTS
N06AX Other antidepressants
N06AX23 Desvenlafaxine
D11619 Desvenlafaxine succinate anhydrous
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01658 Serotonin and norepinephrine reuptake inhibitor (SNRI)
DG00963 Desvenlafaxine
D11619 Desvenlafaxine succinate anhydrous
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG00963 Desvenlafaxine
D11619 Desvenlafaxine succinate anhydrous
DG02924 UGT substrate
DG00963 Desvenlafaxine
D11619 Desvenlafaxine succinate anhydrous
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D11619 Desvenlafaxine succinate anhydrous
SLC6A4 (HTT)
D11619 Desvenlafaxine succinate anhydrous
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D11619
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01658 Serotonin and norepinephrine reuptake inhibitor (SNRI)
DG00963 Desvenlafaxine
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG00963 Desvenlafaxine
DG02924 UGT substrate
DG00963 Desvenlafaxine
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 27
1 O6a O 20.7242 -16.6806
2 C6a C 21.9752 -15.9856
3 C1b C 23.1567 -16.6806
4 C1b C 24.3382 -15.9856
5 C6a C 25.5197 -16.6806
6 O6a O 26.7707 -15.9856
7 O6a O 21.9752 -14.5956
8 O6a O 25.5197 -18.0707
9 C8x C 11.7586 -17.1671
10 C8y C 11.7586 -18.6267
11 C8x C 12.9401 -19.3217
12 C8x C 14.1216 -18.6267
13 C8y C 14.1216 -17.1671
14 C8x C 12.9401 -16.4721
15 C1x C 16.6236 -18.6267
16 C1z C 16.6236 -17.1671
17 C1c C 15.3031 -16.4721
18 C1x C 17.8051 -19.3217
19 C1x C 18.9866 -18.6267
20 C1x C 18.9866 -17.1671
21 C1x C 17.8051 -16.4721
22 O1a O 10.5771 -19.3217
23 O1a O 16.6236 -15.7771
24 C1b C 15.3031 -15.0821
25 N1c N 14.1216 -14.4566
26 C1a C 12.8706 -15.1516
27 C1a C 14.1216 -12.9971
BOND 27
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 2 7 2
7 5 8 2
8 9 10 2
9 10 11 1
10 11 12 2
11 12 13 1
12 13 14 2
13 9 14 1
14 15 16 1
15 16 17 1
16 13 17 1
17 15 18 1
18 18 19 1
19 19 20 1
20 20 21 1
21 16 21 1
22 10 22 1
23 16 23 1
24 17 24 1
25 24 25 1
26 25 26 1
27 25 27 1
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