KEGG ORTHOLOGY: K08558

ORTHOLOGY: K08558

Entry

K08558                      KO

Symbol

NR4A2, NURR1

Name

nuclear receptor subfamily 4 group A member 2

Pathway

map04925

Aldosterone synthesis and secretion

map04928

Parathyroid hormone synthesis, secretion and action

Disease

H00057

Parkinson disease

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    K08558  NR4A2, NURR1; nuclear receptor subfamily 4 group A member 2
   04925 Aldosterone synthesis and secretion
    K08558  NR4A2, NURR1; nuclear receptor subfamily 4 group A member 2
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K08558  NR4A2, NURR1; nuclear receptor subfamily 4 group A member 2
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors
    K08558  NR4A2, NURR1; nuclear receptor subfamily 4 group A member 2
Transcription factors [BR:ko03000]
Eukaryotic type
  Zinc finger
   Cys4 nerve growth factor IB-like
    K08558  NR4A2, NURR1; nuclear receptor subfamily 4 group A member 2
Nuclear receptors [BR:ko03310]
4. Nerve growth factor IB like
  4A. Nerve growth factor IB like receptor
   K08558  NR4A2, NURR1; nuclear receptor subfamily 4 group A member 2

Genes

HSA:	4929(NR4A2)

PTR:	459669(NR4A2)

PPS:	100971338(NR4A2)

GGO:	101149681(NR4A2)

PON:	100452042(NR4A2)

PPYG:

129031682(NR4A2)

NLE:	100589731(NR4A2)

HMH:	116810786(NR4A2)

SSYN:

129489467(NR4A2)

MCC:	697077(NR4A2)

MCF:	102125859(NR4A2)

MTHB:

126933024

MNI:	105493223(NR4A2)

CSAB:

103217123(NR4A2)

CATY:

105576001(NR4A2)

PANU:

101000883(NR4A2)

TGE:	112617065 112617083

MLEU:

105548073(NR4A2)

RRO:	104654109(NR4A2)

RBB:	108538767(NR4A2)

TFN:	117094987(NR4A2)

PTEH:

111546104(NR4A2)

CANG:

105516853(NR4A2)

CJC:	100409975(NR4A2)

SBQ:	101028236(NR4A2)

CIMI:

108316964(NR4A2)

ANAN:

105719014(NR4A2)

CSYR:

103259312(NR4A2)

MMUR:

105859134(NR4A2)

LCAT:

123643312(NR4A2)

PCOQ:

105807397(NR4A2)

OGA:	100965317(NR4A2)

MMU:	18227(Nr4a2)

MCAL:

110286025(Nr4a2)

MPAH:

110318277(Nr4a2)

RNO:	54278(Nr4a2)

MCOC:

116090185(Nr4a2)

ANU:	117703936(Nr4a2)

MUN:	110557168(Nr4a2)

CGE:	100766422(Nr4a2)

MAUA:

101825048(Nr4a2)

PROB:

127222507(Nr4a2)

PLEU:

114696431(Nr4a2)

MORG:

121433250(Nr4a2)

MFOT:

126489399

AAMP:

119819118(Nr4a2)

NGI:	103741047(Nr4a2)

HGL:	101717009(Nr4a2)

CPOC:

100721755(Nr4a2)

CCAN:

109700729(Nr4a2)

DORD:

105994529(Nr4a2)

DSP:	122110805(Nr4a2)

PLOP:

125350657(Nr4a2)

NCAR:

124980303

MMMA:

107136865(Nr4a2)

OCU:

100352580

OPI:	101530970(NR4A2)

TUP:	102472863(NR4A2)

GVR:	103586330(NR4A2)

CFA:	478754(NR4A2)

CLUD:

112674734(NR4A2)

VVP:	112916496(NR4A2)

VLG:	121501333(NR4A2)

NPO:	129498956(NR4A2)

AML:	100482377(NR4A2)

UMR:	103659857(NR4A2)

UAH:	113250870(NR4A2)

UAR:	123781928(NR4A2)

ELK:

111161610

LLV:

125095472

MPUF:

101680736(NR4A2)

MNP:	132013756(NR4A2)

MLK:	131827206(NR4A2)

NVS:	122902505(NR4A2)

ORO:	101384580(NR4A2)

EJU:	114216495(NR4A2)

ZCA:	113920787(NR4A2)

MLX:	118012432(NR4A2)

NSU:	110591939(NR4A2)

LWW:	102739363(NR4A2)

FCA:	101089537(NR4A2)

PYU:	121030579(NR4A2)

PCOO:

112871047(NR4A2)

PBG:	122481348(NR4A2)

PVIV:

125173396(NR4A2)

LRUF:

124516535

PTG:	102958805(NR4A2)

PPAD:

109271410(NR4A2)

PUC:

125911613

AJU:

106979049

HHV:	120245853(NR4A2)

BTA:	540245(NR4A2)

BOM:	102277637(NR4A2)

BIU:	109567528(NR4A2)

BBUB:

102403925(NR4A2)

BBIS:

104988650(NR4A2)

CHX:	102169808(NR4A2)

OAS:	101114494(NR4A2)

BTAX:

128064829(NR4A2)

ODA:	120854812(NR4A2)

CCAD:

122453846(NR4A2)

MBEZ:

129538031(NR4A2)

SSC:	100157120(NR4A2)

CFR:	102508486(NR4A2)

CBAI:

105081919(NR4A2)

CDK:	105093714(NR4A2)

VPC:	102533204(NR4A2)

BACU:

103018599(NR4A2)

BMUS:

118898390(NR4A2)

LVE:	103073180(NR4A2)

OOR:	101287666(NR4A2)

DLE:	111172767(NR4A2)

PCAD:

102977310(NR4A2)

PSIU:

116756865(NR4A2)

NASI:

112393645(NR4A2)

ECB:	100050666(NR4A2)

EPZ:	103563481(NR4A2)

EAI:	106841970(NR4A2)

MYB:	102239345(NR4A2)

MYD:	102764654(NR4A2)

MMYO:

118661612(NR4A2)

MLF:	102438825(NR4A2)

MDT:	132238624(NR4A2)

PKL:	118709570(NR4A2)

EFUS:

103283397(NR4A2)

MNA:	107545920(NR4A2)

DRO:	112322290(NR4A2)

SHON:

118974416(NR4A2)

AJM:	119053198(NR4A2)

PDIC:

114494289(NR4A2)

PHAS:

123832098(NR4A2)

MMF:	118625490(NR4A2)

PPAM:

129061637(NR4A2)

HAI:	109379831(NR4A2)

RFQ:	117026267(NR4A2)

PALE:

102878015(NR4A2)

PGIG:

120596819(NR4A2)

PVP:	105291427(NR4A2)

RAY:	107513423(NR4A2)

MJV:	108392572(NR4A2)

TOD:	119255845(NR4A2)

SARA:

101543296(NR4A2)

SETR:

126008842(NR4A2)

LAV:	100655238(NR4A2)

TMU:

101355181

ETF:	101657401(NR4A2)

DNM:	101431054(NR4A2)

MDO:	100014732(NR4A2)

GAS:	123242253(NR4A2)

SHR:	100927247(NR4A2)

AFZ:

127554646

PCW:	110220764(NR4A2)

TVP:	118839586(NR4A2)

OAA:	100081383(NR4A2)

GGA:	424320(NR4A2)

PCOC:

116227470(NR4A2)

CJO:	107317024(NR4A2)

TPAI:

128076877(NR4A2)

LMUT:

125697047(NR4A2)

NMEL:

110400306(NR4A2)

APLA:

101801493(NR4A2)

ACYG:

106043875(NR4A2)

CATA:

118257731(NR4A2)

AFUL:

116490951(NR4A2)

TGU:	100220944(NR4A2)

LSR:	110478811(NR4A2)

SCAN:

103814613(NR4A2)

PMOA:

120497334(NR4A2)

OTC:	121338394(NR4A2)

PRUF:

121352784

GFR:	102041933(NR4A2)

FAB:	101809133(NR4A2)

OMA:	130255758(NR4A2)

PHI:	102109884(NR4A2)

PMAJ:

107207255(NR4A2)

CCW:	104694111(NR4A2)

CBRC:

103616780(NR4A2)

ETL:	114069164(NR4A2)

ZLE:	135450481(NR4A2)

SVG:	106861911(NR4A2)

MMEA:

130587698

HRT:	120755017(NR4A2)

SATI:

136363756(NR4A2)

FPG:	101913938(NR4A2)

FCH:	102054542(NR4A2)

NNT:

104403901

SHAB:

115608373(NR4A2)

TALA:

104356534

ACHC:

115342683(NR4A2)

HLE:	104829052(NR4A2)

AGEN:

126043098

GCL:

127018146

DPUB:

104296937(NR4A2) 104306037

EGZ:	104135264(NR4A2)

NNI:	104012366(NR4A2)

PADL:

103925336(NR4A2)

AFOR:

103893886(NR4A2)

CLV:	102090093(NR4A2)

CUCA:

104056188(NR4A2)

CPEA:

104391743(NR4A2)

CVF:	104286829(NR4A2)

RTD:	128913072(NR4A2)

AAM:	106486543(NR4A2)

AROW:

112962262(NR4A2)

NPD:	112946362(NR4A2)

TGT:	104572348(NR4A2)

DNE:	112984851(NR4A2)

SCAM:

104138769(NR4A2)

ASN:	102374486(NR4A2)

AMJ:	106736708(NR4A2)

CPOO:

109323163(NR4A2)

GGN:	109301304(NR4A2)

PSS:	102453599(NR4A2)

CMY:	102930700(NR4A2)

DCC:	119863771(NR4A2)

CPIC:

101940290(NR4A2)

TST:	117885077(NR4A2)

CABI:

116830011(NR4A2)

MRV:	120374774(NR4A2)

ACS:	100552871(nr4a2)

ASAO:

132776007(NR4A2)

PVT:	110083041(NR4A2)

SUND:

121932803(NR4A2)

PBI:	103059731(NR4A2)

PMUR:

107291504(NR4A2)

CTIG:

120304615(NR4A2)

TSR:	106538826(NR4A2)

PGUT:

117670275(NR4A2)

APRI:

131202920(NR4A2)

PTEX:

113434149(NR4A2)

NSS:	113416523 113416577

VKO:	123017242(NR4A2)

PMUA:

114605187(NR4A2)

PRAF:

128422781(NR4A2)

ZVI:	118093038(NR4A2)

HCG:	128339977(NR4A2)

GJA:	107110732(NR4A2)

STOW:

125426566(NR4A2)

EMC:	129325299(NR4A2)

XLA:	108701333(nr4a2.L) 108702961(nr4a2.S)

XTR:	100101682(nr4a2)

NPR:	108784367(NR4A2)

RTEM:

120944099(NR4A2)

BBUF:

121007761(NR4A2)

BGAR:

122944952(NR4A2)

MUO:	115474202(NR4A2)

GSH:	117361107(NR4A2)

DRE:	100008101(nr4a2a) 436679(nr4a2b)

SRX:	107705590 107709734 107734489 107745273

SANH:

107657406 107660073 107688872

SGH:	107555438(nr4a2) 107567064 107572156 107584763

CCAR:

109069610 109069614 109105968

CAUA:

113050808 113082924 113093216 113109155(nr4a2)

CGIB:

127959947 127964631 128015373 128020301

PTET:

122346371(nr4a2b) 122351275(nr4a2a)

LROH:

127166281(nr4a2b) 127170922(nr4a2a)

OMC:	131542198(nr4a2b) 131547418(nr4a2a)

PPRM:

120491281(nr4a2b) 120494962 120494963

RKG:	130086091(nr4a2a) 130101213(nr4a2b)

MAMB:

125269892(nr4a2a) 125274339(nr4a2b)

CIDE:

127514756 127518800

CERY:

137011754(nr4a2b) 137036002(nr4a2a)

MASI:

127445840 127446835 127448066 127449674

TROS:

130555662(nr4a2a) 130556759(nr4a2b)

TDW:	130424450(nr4a2b) 130427652(nr4a2a)

MANU:

129450452(nr4a2b) 129452162(nr4a2a)

IPU:	108266113(nr4a2a) 108272367(nr4a2b)

IFU:	128609085(nr4a2a) 128616231(nr4a2b)

PHYP:

113523803(nr4a2) 113538236

SMEO:

124380395(nr4a2a) 124383113(nr4a2b)

TFD:	113642600(nr4a2a) 113657165(nr4a2b)

TVC:	132845000(nr4a2b) 132850716(nr4a2a)

TRN:	134316482(nr4a2b) 134324300(nr4a2a)

AMEX:

103029080(nr4a2b) 103031524(nr4a2a)

CMAO:

118807788(nr4a2b) 118810387(nr4a2a)

EEE:	113574662(nr4a2) 113582614

CHAR:

105902669(nr4a2a) 105912399

TRU:	101072378(nr4a2)

TFS:	130534340(nr4a2a)

TNG:	GSTEN00030552G001

LCO:	104920078(nr4a2) 104929095

NCC:	104954407 104964157

TBEN:

117477403 117485756(nr4a2a)

CGOB:

115019118 115026291(nr4a2)

PGEO:

117457861 117466874(nr4a2a)

GACU:

117539277 117556840(nr4a2a)

EMAC:

134860972 134867383(nr4a2a)

ELY:	117248123(nr4a2a) 117249849

EFO:	125884981 125900065(nr4a2a)

PLEP:

121949080(nr4a2a)

SLUC:

116044831 116049372(nr4a2a)

ECRA:

117939658 117953474(nr4a2a)

ESP:	116673803 116698187(nr4a2)

PFLV:

114550990 114564568(nr4a2)

GAT:	120821992 120834431(nr4a2a)

PPUG:

119220212 119229315(nr4a2a)

AFB:	129104612(nr4a2a) 129111690

CLUM:

117744061 117750561(nr4a2a)

PSWI:

130204536 130208503(nr4a2a)

MSAM:

119904204(nr4a2a)

SCHU:

122871801 122885855(nr4a2a)

CUD:	121506304 121522290(nr4a2a)

ALAT:

119015425 119025494(nr4a2a)

MZE:	101475755(nr4a2) 101487266

ONL:	100694602 100708353(nr4a2)

OAU:	116310266 116323016(nr4a2a)

OLA:	100049370(nr4a2) 101171058

OML:	112154745(nr4a2a) 112156609

CSAI:

133424935 133445990(nr4a2a)

XMA:	102231076(nr4a2) 102233241

XCO:	114140257 114147511(nr4a2)

XHE:	116715594 116722506(nr4a2)

PRET:

103461679(nr4a2) 103473768

PFOR:

103149402 103150587(nr4a2)

PLAI:

106946927(nr4a2) 106958012

PMEI:

106920550 106923817(nr4a2)

GAF:	122827374 122840039(nr4a2a)

PPRL:

129361536(nr4a2a) 129378705

CVG:	107086455 107087122(nr4a2)

CTUL:

119781573 119783895(nr4a2a)

GMU:	124861316 124870957(nr4a2a)

NFU:	107384697 107390093(nr4a2)

KMR:	108240718(nr4a2a) 108251072

ALIM:

106523315(nr4a2) 106524676

NWH:	119419109(nr4a2a) 119428897

AOCE:

111573311(nr4a2) 111581942

MCEP:

125017198(nr4a2a)

CSEM:

103389594 103392181(nr4a2)

POV:	109631045(nr4a2) 109645780

SSEN:

122765460(nr4a2a) 122784920

HHIP:

117755202(nr4a2a) 117774461

HSP:	118103235 118120580(nr4a2a)

PPLT:

128431249 128456136(nr4a2a)

SMAU:

118302139 118320344(nr4a2a)

LCF:	108873077 108901097(nr4a2a)

SDU:	111218523(nr4a2) 111233085

SLAL:

111651228(nr4a2) 111670296

XGL:	120798017 120802051(nr4a2a)

HCQ:	109511576 109528377

SSCV:

125973555 125988273

SBIA:

133506055 133512179(nr4a2a)

PEE:	133403864 133410498(nr4a2a)

PTAO:

133479472 133487135(nr4a2a)

BPEC:

110162212 110166562(nr4a2)

MALB:

109957067(nr4a2) 109960526

BSPL:

114847233(nr4a2a) 114851322

SJO:	128354244 128367857(nr4a2a)

SASA:

106574868 106575779 106575783 106581823(nr4a2) 106586168

STRU:

115156089(nr4a2) 115160695 115179672 115196404

OTW:	112225170 112235696 112239131

OMY:	110495532 110495534 110501524 110520047

OGO:	124016960 124019670 124042876

ONE:	115108319 115115978 115130778(nr4a2)

OKI:	109865936 109871056(nr4a2) 109878278

OKE:	118367131 118375309 118385980

SALP:

111959927(nr4a2) 111974472

SNH:	120033116 120033632 120057851 120063843

CCLU:

121536055 121536684 121551741

ELS:	105019719 105022426(nr4a2)

SFM:	108927908(nr4a2) 108928919

PKI:	111858363 111859903(nr4a2)

AANG:

118213819 118222780

LOC:	102691033(nr4a2)

PSPA:

121322288 121323156

ARUT:

117409121 117426484(nr4a2a)

PSEX:

120531745

LCM:	102360581(NR4A2)

CMK:	103173799(nr4a1) 103176410(nr4a2a)

RTP:

109928168

CPLA:

122551607

HOC:

132817452

LERI:

129698799(nr4a2a)

PMRN:

116949444

LRJ:	133345273 133345994

BFO:

118406140

BBEL:

109480398

CIN:	778703(nr41/42/43)

SCLV:

SPU:

LPIC:

APLC:

SKO:	100371439 100373323

DME:	Dmel_CG1864(Hr38)

DER:

6548883

DSE:

6618183

DSI:	Dsimw501_GD21688(Dsim_GD21688)

DYA:	Dyak_GE13549

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI19631

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

109417683 109622172 115255395

ASUA:

134213111

CQU:	CpipJ_CPIJ004609 CpipJ_CPIJ004610

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:	105676504(Hr38)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

AROA:

TCA:	100142491(Hr38)

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

DVV:

NVL:

DCOR:

135795846(Hr38)

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_211084

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CFEL:

CCRN:

API:

DNX:

AGS:	114130965 114131769

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

106689598(Hr38)

NLU:

111048087

HVI:

124364663

MQU:	129000719 129000932

PHU:	Phum_PHUM411130

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_220366

DMK:

116925196

DPZ:

124345339

PVM:	113806746 113821695

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:	111702548 111707555 111709236

LSM:

TCF:

PPOI:

ISC:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:	107363716 107363741

DPTE:

113795724

DFR:

124499377

CSCU:

111629592

CVS:	136969856(Hr38)

PTEP:

ABRU:

UDV:

SDM:

LPOL:

CEL:	CELE_C48D5.1(nhr-6)

CBR:	CBG_09761(Cbr-nhr-6)

CRQ:	GCK72_009709

LOA:	LOAG_17747

LGI:	LOTGIDRAFT_136520

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:	124264107 124270623

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

MMER:

RPHI:

MAEA:

OBI:

LJP:

LAK:

SMM:	Smp_139200

EGL:

EGR_02914

LLON:

135499304

» show all

Reference

PMID:25089663

Authors

Ranhotra HS

Title

The NR4A orphan nuclear receptors: mediators in metabolism and diseases.

Journal

J Recept Signal Transduct Res 35:184-8 (2015)
DOI:10.3109/10799893.2014.948555

Reference

PMID:7877627

Authors

Mages HW, Rilke O, Bravo R, Senger G, Kroczek RA

Title

NOT, a human immediate-early response gene closely related to the steroid/thyroid hormone receptor NAK1/TR3.

Journal

Mol Endocrinol 8:1583-91 (1994)
DOI:10.1210/mend.8.11.7877627

Sequence

[hsa:4929]

LinkDB

DBGET integrated database retrieval system