KEGG ORTHOLOGY: K10655

ORTHOLOGY: K10655

Entry

K10655                      KO

Symbol

TRIM63, MURF1

Name

tripartite motif-containing protein 63 [EC:2.3.2.27]

Pathway

map04820

Cytoskeleton in muscle cells

Disease

H00292

Hypertrophic cardiomyopathy

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    K10655  TRIM63, MURF1; tripartite motif-containing protein 63
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K10655  TRIM63, MURF1; tripartite motif-containing protein 63
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     K10655  TRIM63, MURF1; tripartite motif-containing protein 63
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  Single Ring-finger type E3
   TRIM/RBCC proteins
    K10655  TRIM63, MURF1; tripartite motif-containing protein 63

Genes

HSA:	84676(TRIM63)

PTR:	469240(TRIM63)

PPS:	100978743(TRIM63)

GGO:	101150265(TRIM63)

PON:	100434716(TRIM63)

PPYG:

129011730(TRIM63)

NLE:	100581509(TRIM63)

HMH:	116812615(TRIM63)

SSYN:

129472273(TRIM63)

MCC:	713802(TRIM63)

MCF:	102120812(TRIM63)

MTHB:

126955449

MNI:	105494490(TRIM63)

CSAB:

103225319(TRIM63)

CATY:

105594947(TRIM63)

PANU:

101010407(TRIM63)

TGE:	112608387(TRIM63)

MLEU:

105540876(TRIM63)

RRO:	104656081(TRIM63)

RBB:	108518041(TRIM63)

TFN:	117093076(TRIM63)

PTEH:

111547546(TRIM63)

CANG:

105521397(TRIM63)

CJC:	100413206(TRIM63)

SBQ:	101052057(TRIM63)

CIMI:

108308710(TRIM63)

ANAN:

105708633(TRIM63)

CSYR:

103267600(TRIM63)

MMUR:

105863562(TRIM63)

LCAT:

123634377(TRIM63)

PCOQ:

105811669(TRIM63)

OGA:	100961587(TRIM63)

MMU:	433766(Trim63)

MCAL:

110293067(Trim63)

MPAH:

110323486(Trim63)

RNO:	140939(Trim63)

MCOC:

116095607(Trim63)

ANU:	117708819(Trim63)

ASYL:

127681438(Trim63)

MUN:	110552708(Trim63)

CGE:	100772288(Trim63)

MAUA:

101832210(Trim63)

PROB:

127213339(Trim63)

PLEU:

114705994(Trim63)

MORG:

121448282(Trim63)

MFOT:

126508172

AAMP:

119817186(Trim63)

NGI:	103737103(Trim63)

HGL:	101705659(Trim63)

CPOC:

100716828(Trim63)

CCAN:

109683078(Trim63)

DORD:

105998359(Trim63)

DSP:	122115261(Trim63)

DMER:

138838271(Trim63)

PLOP:

125354752(Trim63)

NCAR:

124961972

MMMA:

107142096(Trim63)

ITI:	101977049(Trim63)

OCU:

100347164

OPI:	101532553(TRIM63)

OCZ:	121156120(TRIM63)

TUP:	102477091(TRIM63)

GVR:	103585087(TRIM63)

CFA:	487362(TRIM63)

CLUD:

112659913(TRIM63)

VVP:	112931727(TRIM63)

VLG:	121497343(TRIM63)

NPO:	129513307(TRIM63)

AML:	100483233(TRIM63)

UMR:	103666522(TRIM63)

UAH:	113268472(TRIM63)

UAR:	123782318(TRIM63)

ELK:

111154792

LLV:

125098684

MPUF:

101682637(TRIM63)

MNP:	132001196(TRIM63)

MLK:	131809990(TRIM63)

NVS:	122898617(TRIM63)

ORO:	101378804(TRIM63)

EJU:	114217187(TRIM63)

ZCA:	113916414(TRIM63)

MLX:	118019849(TRIM63)

NSU:	110575394(TRIM63)

LWW:	102741436(TRIM63)

FCA:	101083951(TRIM63)

PYU:	121023652(TRIM63)

PCOO:

112862444(TRIM63)

PBG:	122480111(TRIM63)

PVIV:

125172377(TRIM63)

LRUF:

124515765

LGF:	123597397(TRIM63)

AJU:

106977617

PTG:	102962024(TRIM63)

PPAD:

109256777(TRIM63)

PUC:

125912920

PLEZ:

122227259(TRIM63)

HHV:	120232066(TRIM63)

BTA:	528912(TRIM63)

BOM:	102267864(TRIM63)

BIU:	109573566(TRIM63)

BBUB:

102416323(TRIM63)

BBIS:

104981141(TRIM63)

CHX:	102172216(TRIM63)

OAS:	101113132(TRIM63)

BTAX:

128061637(TRIM63)

CSUM:

138076376(TRIM63)

ODA:	120855059(TRIM63)

CCAD:

122426609(TRIM63)

MREE:

136164731(TRIM63)

OVR:	110147613(TRIM63)

SSC:	100431101(TRIM63)

CFR:	102521022(TRIM63)

CBAI:

105063478(TRIM63)

CDK:	105100674(TRIM63)

VPC:	102545149(TRIM63)

BACU:

103003953(TRIM63)

BMUS:

118904107(TRIM63)

LVE:	103091118(TRIM63)

OOR:	101280381(TRIM63)

LALB:

132515085(TRIM63)

GMF:	115866994(TRIM63)

DDP:	132428668(TRIM63)

DLE:	111163348(TRIM63)

PCAD:

102975358(TRIM63)

PSIU:

116760473(TRIM63)

PPHC:

136120647(TRIM63)

NASI:

112414356(TRIM63)

ECB:	100071234(TRIM63)

EPZ:	103556784(TRIM63)

EAI:	106839931(TRIM63)

MYB:	102246463(TRIM63)

MYD:	102760808(TRIM63)

MMYO:

118676747(TRIM63)

MLF:	102435887(TRIM63)

MDT:	132231500(TRIM63)

MYUM:

139003030(TRIM63)

PKL:	118722788(TRIM63)

EFUS:

103291924(TRIM63)

MNA:	107539849(TRIM63)

DRO:	112299486(TRIM63)

SHON:

118977775(TRIM63)

AJM:	119042168(TRIM63)

PDIC:

114497323(TRIM63)

PHAS:

123832318(TRIM63)

MMF:	118626613(TRIM63)

PPAM:

129069199(TRIM63)

HAI:	109386708(TRIM63)

RFQ:	117027803(TRIM63)

PALE:

102894106(TRIM63)

PGIG:

120596317(TRIM63)

PVP:	105290483(TRIM63)

RAY:	107502531(TRIM63)

MJV:	108398789(TRIM63)

TOD:	119236318(TRIM63)

SARA:

101556601(TRIM63)

SFUM:

130032024(TRIM63)

SETR:

126011747(TRIM63)

LAV:	100670633(TRIM63)

TMU:

101344379

ETF:	101653347(TRIM63)

DNM:	101430152(TRIM63)

MDO:	100015426(TRIM63)

GAS:	123240381(TRIM63)

SHR:	100919501(TRIM63)

AFZ:

127555662

PCW:	110206110(TRIM63)

TVP:	118835323(TRIM63)

PBRV:

138154632(TRIM63)

MLAO:

141508947(TRIM63)

OAA:	100086074(TRIM63)

TACU:

119938300(TRIM63)

GGA:	426754(TRIM63)

PCOC:

116229909(TRIM63)

MGP:	100551180(TRIM63)

CJO:	107324083(TRIM63)

TPAI:

128088249(TRIM63)

LMUT:

125703790(TRIM63)

NMEL:

110387266(TRIM63)

APLA:

119713599(TRIM63)

ACYG:

106037935(TRIM63)

CATA:

118255664(TRIM63)

AFUL:

116498214(TRIM63)

TGU:	100221817(TRIM63)

LSR:	110472892(TRIM63)

SCAN:

103823581(TRIM63)

PMOA:

120513891(TRIM63)

OTC:	121342766(TRIM63)

PRUF:

121351195(TRIM63)

ATRC:

139602820(TRIM63)

GFR:	102039371(TRIM63)

FAB:	101816477(TRIM63)

OMA:	130262322(TRIM63)

PHI:	102110991(TRIM63)

PMAJ:

107214019(TRIM63)

CCAE:

111939093(TRIM63)

CBRC:

103616908(TRIM63)

ACOE:

138122055(TRIM63)

ETL:	114070344(TRIM63)

ZAB:	102066630(TRIM63)

ZLE:	135457286(TRIM63)

ACHL:

103809639(TRIM63)

MMEA:

130583293(TRIM63)

HRT:	120763140(TRIM63)

SATI:

136371161(TRIM63)

CCIC:

134053843(TRIM63)

FPG:	101922009(TRIM63)

FCH:	102057211(TRIM63)

CCRI:

104167812

NNT:

104412506

SHAB:

115615980(TRIM63)

ACUN:

113488266(TRIM63)

TALA:

116964267(TRIM63)

ACHC:

115351766(TRIM63)

HLE:	104837310(TRIM63)

AGEN:

126046976

HHAR:

128152801(TRIM63)

GCL:

127025013

CSTI:

104561627(TRIM63)

LDI:	104354607(TRIM63)

MNB:	103775682(TRIM63)

DPUB:

104307498(TRIM63)

PPUS:

135190945(TRIM63)

BRHI:

104491321

EGZ:	104134952(TRIM63)

NNI:	104017845(TRIM63)

AFOR:

103896367(TRIM63)

CBOR:

142093035(TRIM63)

CBOY:

140662249(TRIM63)

MAME:

142419298(TRIM63)

CLV:	102083900(TRIM63)

CNIC:

135997703(TRIM63)

MUI:	104546362(TRIM63)

PGUU:

104468808(TRIM63)

EHS:

104513766

CMAC:

104485015

CUCA:

104061523(TRIM63)

TEO:	104381233(TRIM63)

BREG:

104641896

ACAR:

104522794(TRIM63)

CPEA:

104394134(TRIM63)

CVF:	104283972(TRIM63)

RTD:	128918880(TRIM63)

CRID:

134525335(TRIM63)

LMIC:

141732989(TRIM63)

AAM:	106488915(TRIM63)

AROW:

112964440(TRIM63)

NPD:	112950899(TRIM63)

TGT:	104569449(TRIM63)

DNE:	112982126(TRIM63)

SCAM:

104141969

ASN:	102376601(TRIM63) 112551795

AMJ:	102576413(TRIM63) 109285091

CPOO:

109318647(TRIM63)

GGN:	109294164(TRIM63)

PSS:	102453978(TRIM63)

CIZ:	142001249(TRIM63)

CMY:	102931195(TRIM63)

CCAY:

125624695(TRIM63)

DCC:	119845503(TRIM63)

CPIC:

101953342(TRIM63)

TST:	117868328(TRIM63)

CABI:

116837994(TRIM63)

MRV:	120389272(TRIM63)

ACS:	100568200(trim63)

ASAO:

132780722(TRIM63)

PVT:	110084148(TRIM63)

SUND:

121916013(TRIM63)

PBI:	103068155(TRIM63)

PMUR:

107295685(TRIM63)

CTIG:

120314312(TRIM63)

TSR:	106539674(TRIM63)

PGUT:

117663390(TRIM63)

PCAE:

139320896(TRIM63)

APRI:

131204191(TRIM63)

PTEX:

113437528(TRIM63)

NSS:	113417576(TRIM63)

VKO:	123025939(TRIM63)

PMUA:

114601544(TRIM63)

PRAF:

128418727(TRIM63)

ZVI:	118087215(TRIM63)

HCG:	128333254(TRIM63)

GJA:	107110807(TRIM63)

STOW:

125434968(TRIM63)

EMC:	129343198(TRIM63)

XLA:	100036938(trim63.L) 446518(trim63.S)

XTR:	780012(trim63)

NPR:	108795722(TRIM63)

RTEM:

120927316(TRIM63)

ACAT:

141128693(TRIM63)

BBUF:

120995194(TRIM63)

BGAR:

122923370 122932856

DTC:	141047462(TRIM63)

PWL:	138284814(TRIM63)

MUO:	115479854(TRIM63)

GSH:	117365879(TRIM63)

DRE:	394070(trim63b) 415223(trim63a)

SGH:

107586317

CCAR:

109062517 109074869 109084181(trim63a) 109096735

CAUA:

113098483

CGIB:

127959710 128015433 128019790

PTET:

122347616(trim63a)

LROH:

127166289(trim63a)

GRF:	141340828(trim63b) 141347121(trim63a)

OMC:	131543046(trim63a)

PPRM:

120486086(trim63a)

RKG:	130069609(trim63a)

MAMB:

125274267(trim63a)

CIDE:

127513910

CERY:

137011556(trim63a)

MASI:

127446227 127447083 127448374 127449235

TROS:

130556001(trim63b) 130556876(trim63a)

TDW:	130424752(trim63a) 130427904(trim63b)

MANU:

129451171(trim63a)

PDAB:

135717824(trim63a)

IPU:	108261132 108272965

IFU:	128608535(trim63b) 128615718(trim63a)

SMEO:

124382791(trim63b) 124383484(trim63a)

TFD:	113634443(trim63a) 113647324(trim63b)

TVC:	132844011(trim63a) 132849887(trim63b)

CGAR:

128524617(trim63b) 128526851(trim63a)

NGRA:

132884337(trim63a) 132891151(trim63b)

TRN:	134316440(trim63a) 134324204(trim63b)

AMEX:

103045516(trim63b) 103047531(trim63a)

CMAO:

118804094(trim63b) 118807739(trim63a)

CHAR:

105896535(trim63a) 105905954(trim63b)

SPIL:

134071091(trim63a) 134078638(trim63b)

ASAD:

121698339(trim63a) 121698482(trim63b)

TRU:

101067000

TFS:	130530766(trim63b)

TNG:	GSTEN00033121G001

NCC:	104947601 104957775(trim63)

TBEN:

117469106 117485726(trim63b)

CGOB:

115026168 115026282

PGEO:

117466651(trim63b)

GACU:

117536984(trim63b)

EMAC:

134861119 134867717(trim63b)

ELY:	117249979 117251401(trim63b)

EFO:	125885058 125899752(trim63b)

PLEP:

121949034(trim63b) 121962899

SLUC:

116044801 116053539(trim63b)

ECRA:

117940172 117952555(trim63b)

ESP:

116698430

GAT:	120834020(trim63b)

PPUG:

119220846 119229084(trim63b)

AFB:	129104309(trim63b) 129111994

CLUM:

117745190 117750910(trim63b)

PSWI:

130204517 130206027(trim63b)

CANA:

137782914(trim63b)

CVE:	137883618(trim63b)

MSAM:

119903452(trim63b) 119909919

SCHU:

122871968 122885771(trim63b)

CUD:	121523008(trim63b)

SPUL:

138592720(trim63b)

LMIX:

132987124(trim63b)

HTC:	141808913(trim63b)

ALAT:

119015016 119026299(trim63b)

ASTR:

137605150(trim63b)

MZE:

101465308

OAU:	116335015(trim63b)

OML:	112138016(trim63b)

CSAI:

133445688(trim63b)

XHE:

116723285

PLAI:

106962518

GAF:	122840294(trim63b)

PPRL:

129374501(trim63b)

CVG:

107099045

CTUL:

119798979(trim63b)

GMU:	124871472(trim63b)

KMR:	108243434(trim63b)

NWH:	119419497(trim63b)

AOCE:

111575550(trim63b)

EJA:	138201441(trim63b)

BFRE:

138621015(trim63b)

MCEP:

125017573(trim63b)

CSEM:

103392343

SSEN:

122765003(trim63b)

SSOE:

131450439(trim63b)

HHIP:

117773014(trim63a)

HSP:	118103318 124854609(trim63b)

PPLT:

128431025 128456373(trim63b)

SMAU:

118300240 124851001(trim63b)

SDU:

111218532

SLAL:

111663424

XGL:	120787431(trim63a)

SSCV:

125973521(trim63b)

SBIA:

133512461(trim63b)

PEE:	133410806(trim63b)

PTAO:

133486835(trim63b)

BPEC:

110158190

ENY:	140359955(trim63b)

BSPL:

114846795(trim63b) 114851211

SJO:	128367588(trim63b)

SSCO:

133992968(trim63b)

TTY:	137192311(trim63b)

SASA:

100194537 100194566 101448020 101448050(murf1)

OTW:	112225083 112234919 112266288(trim63a)

OMY:	100505417 100505419(trim63b) 110516772 110519976

OGO:	124025124 124025149 124041163 124043751

OKE:	118367195 118385865

OMM:	135519906 135542991(trim63a)

SNH:	120050510 120050512 120058187(trim63b) 120064488

SFON:

129816472 129821400(trim63b) 129840424 129840429

CCLU:

121536622 121550766 121576055

OEP:	134007734(trim63a) 134017100(trim63b)

SFM:	108931859(trim63)

PKI:

111854248

AANG:

118213913(trim63b) 118233123

AROT:

135240518 135261175

CCOG:

133116397(trim63b) 133136877

LOC:	102686817 102687014(trim63)

PSPA:

121303378 121322437 121323138

ARUT:

117412633 117413127 117413843 117427184

PSEX:

120517770 120530696

LCM:	102355372(TRIM63)

CMK:

RTP:

CPLA:

HOC:

LERI:

HAKA:

PFLL:

HRF:	124121360 124131661 124144183

HRJ:

124274219

PMAX:

117315831

ATEN:

116308213

PTM:	GSPATT00019138001

» show all

Reference

PMID:11927605

Authors

McElhinny AS, Kakinuma K, Sorimachi H, Labeit S, Gregorio CC

Title

Muscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-1.

Journal

J Cell Biol 157:125-36 (2002)
DOI:10.1083/jcb.200108089

Sequence

[hsa:84676]

LinkDB

DBGET integrated database retrieval system