KEGG ORTHOLOGY: K11485

ORTHOLOGY: K11485

Entry

K11485                      KO

Symbol

MTF2, PCL2

Name

metal regulatory transcription factor 2

Pathway

map03083

Polycomb repressive complex

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09126 Chromosome
   03083 Polycomb repressive complex
    K11485  MTF2, PCL2; metal regulatory transcription factor 2
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K11485  MTF2, PCL2; metal regulatory transcription factor 2
   03036 Chromosome and associated proteins
    K11485  MTF2, PCL2; metal regulatory transcription factor 2
Transcription factors [BR:ko03000]
Eukaryotic type
  Zinc finger
   Other zinc fingers
    K11485  MTF2, PCL2; metal regulatory transcription factor 2
Chromosome and associated proteins [BR:ko03036]
Eukaryotic type
  Histone modification proteins
   Polycomb repressive complex (PRC) and associated proteins
    PRC2.1
     K11485  MTF2, PCL2; metal regulatory transcription factor 2

Genes

HSA:	22823(MTF2)

PTR:	457026(MTF2)

PPS:	100983133(MTF2)

GGO:	101154492(MTF2)

PON:	100173244(MTF2)

NLE:	100590826(MTF2)

HMH:	116469762(MTF2)

MCC:	707104(MTF2)

MCF:	101925643(MTF2)

MTHB:

126964185

MNI:	105485397(MTF2)

CSAB:

103224423(MTF2)

CATY:

105589456(MTF2)

PANU:

101010413(MTF2)

TGE:	112605420(MTF2)

MLEU:

105538520(MTF2)

RRO:	104679509(MTF2)

RBB:	108535550(MTF2)

TFN:	117074810(MTF2)

PTEH:

111555109(MTF2)

CANG:

105510297(MTF2)

CJC:	100402851(MTF2)

SBQ:	101036113(MTF2)

CIMI:

108315010(MTF2)

CSYR:

103277148(MTF2)

MMUR:

105885732(MTF2)

LCAT:

123635394(MTF2)

PCOQ:

105823881(MTF2)

OGA:	100943617(MTF2)

MMU:	17765(Mtf2)

MCAL:

110294918(Mtf2)

MPAH:

110330232(Mtf2)

RNO:	360905(Mtf2)

MCOC:

116068079(Mtf2)

ANU:	117713010(Mtf2)

MUN:	110561432(Mtf2)

CGE:	100764652(Mtf2)

MAUA:

101826723(Mtf2)

PROB:

127232068(Mtf2)

PLEU:

114691825(Mtf2)

MORG:

121433697(Mtf2)

MFOT:

126509670

AAMP:

119807637(Mtf2)

NGI:	103728855(Mtf2) 103731800

HGL:	101709688(Mtf2)

CPOC:

100723500(Mtf2)

CCAN:

109691683(Mtf2)

DORD:

105987078(Mtf2)

DSP:	122106303(Mtf2)

PLOP:

125355551(Mtf2)

NCAR:

124986615

MMMA:

107155052(Mtf2)

OCU:

100353693

OPI:	101522620(MTF2)

TUP:	102486223(MTF2)

GVR:	103604962(MTF2)

CFA:	479948(MTF2)

CLUD:

112640861(MTF2)

VVP:	112918431(MTF2)

VLG:	121487651(MTF2)

NPO:	129519643(MTF2)

AML:	100480331(MTF2)

UMR:	103669367(MTF2)

UAH:	113254401(MTF2)

UAR:	123795208(MTF2)

ELK:

111142966

LLV:

125097574

MPUF:

101684122(MTF2)

MNP:	132001132(MTF2)

MLK:	131808991(MTF2)

NVS:	122900203(MTF2)

ORO:	101374501(MTF2)

EJU:	114196847(MTF2)

ZCA:	113933540(MTF2)

MLX:	118019134(MTF2)

NSU:	110580644(MTF2)

LWW:	102743144(MTF2)

FCA:	101087854(MTF2)

PYU:	121027486(MTF2)

PCOO:

112868648(MTF2)

PBG:	122480782(MTF2)

PVIV:

125172433(MTF2)

LRUF:

124515595

PTG:	102954486(MTF2)

PPAD:

109259965(MTF2)

PUC:

125913365

AJU:

106968072

HHV:	120234547(MTF2)

BTA:	615211(MTF2)

BOM:	102286748(MTF2)

BIU:	109556051(MTF2)

BBUB:

102392540(MTF2)

BBIS:

105003336(MTF2)

CHX:	102188821(MTF2)

OAS:	101104870(MTF2)

BTAX:

128044357(MTF2)

ODA:	120856854(MTF2)

CCAD:

122426134 122436683(MTF2)

MBEZ:

129540573(MTF2)

SSC:	100156808(MTF2)

CFR:	102508729(MTF2)

CBAI:

105065315(MTF2)

CDK:	105085345(MTF2)

VPC:	102526838(MTF2)

BACU:

103019892(MTF2)

BMUS:

118899210(MTF2)

LVE:	103076513(MTF2)

OOR:	101270831(MTF2)

DLE:	111164021(MTF2)

PCAD:

102986076(MTF2)

PSIU:

116757068(MTF2)

NASI:

112398829(MTF2)

ECB:	100051293(MTF2)

EPZ:	103556969(MTF2)

EAI:	106846447(MTF2)

MYB:	102239342(MTF2)

MYD:	102767460(MTF2)

MMYO:

118662035 118675474(MTF2)

MLF:	102440914(MTF2)

PKL:	118724590(MTF2)

EFUS:

103297993(MTF2)

MNA:	107525102(MTF2)

DRO:	112309287(MTF2)

SHON:

118986534(MTF2)

AJM:	119061473(MTF2)

PDIC:

114495976(MTF2)

PHAS:

123824039(MTF2)

MMF:	118627219(MTF2)

PPAM:

129085710(MTF2)

HAI:	109396040(MTF2)

RFQ:	117027439(MTF2)

PALE:

102892033(MTF2)

PGIG:

120583343(MTF2)

PVP:	105289120(MTF2)

RAY:	107504770(MTF2)

MJV:	108390766(MTF2)

TOD:	119237283(MTF2)

SARA:

101555686(MTF2)

SETR:

125999071 126006711(MTF2)

LAV:	100664864(MTF2)

TMU:

101344546

ETF:	101663577(MTF2)

DNM:

101437992

MDO:	100032821(MTF2)

GAS:	123243856(MTF2)

SHR:	100922834(MTF2)

AFZ:

127559498

PCW:	110197948(MTF2)

OAA:	100077121(MTF2)

GGA:	395174(MTF2)

PCOC:

116243555(MTF2)

MGP:	100541519 104912362

CJO:	107317363(MTF2)

TPAI:

128072146(MTF2)

LMUT:

125693032(MTF2)

NMEL:

110402559(MTF2)

APLA:

101801544(MTF2)

ACYG:

106039430(MTF2)

CATA:

118243624(MTF2)

AFUL:

116491823(MTF2)

TGU:	100228056(MTF2)

LSR:	110468303(MTF2)

SCAN:

103814890(MTF2)

PMOA:

120510858(MTF2)

OTC:	121345032(MTF2)

PRUF:

121362060(MTF2)

GFR:	102031611(MTF2)

FAB:	101819632(MTF2)

OMA:	130256052(MTF2)

PHI:	102103970(MTF2)

PMAJ:

107208243(MTF2)

CCAE:

111932793(MTF2)

CCW:	104695343(MTF2)

CBRC:

103612592(MTF2)

ETL:	114055637(MTF2)

ZAB:	102074581(MTF2)

ACHL:

103810971(MTF2)

SVG:	106857877(MTF2)

MMEA:

130578105(MTF2)

HRT:	120756663(MTF2)

FPG:	101917747(MTF2)

FCH:	102057831(MTF2)

CLV:	102096113(MTF2)

EGZ:	104127901(MTF2)

NNI:	104015494(MTF2)

PCRI:

104034777(MTF2)

PLET:

104625344(MTF2)

EHS:	104510237(MTF2)

PCAO:

104052738(MTF2)

ACUN:

113482693(MTF2)

TALA:

104362546(MTF2)

PADL:

103925116(MTF2)

AFOR:

103908141(MTF2)

ACHC:

115349220(MTF2)

HALD:

104322616(MTF2)

HLE:	104841152(MTF2)

AGEN:

126042206

GCL:

127019287

CCRI:

104156652(MTF2)

CSTI:

104552210(MTF2)

CMAC:

104482903(MTF2)

MUI:	104544231(MTF2)

BREG:

104633347(MTF2)

FGA:	104076891(MTF2)

GSTE:

104255282(MTF2)

LDI:	104352180(MTF2)

MNB:	103769073(MTF2)

OHA:	104335427(MTF2)

NNT:	104410166(MTF2)

SHAB:

115612239(MTF2)

DPUB:

104308665(MTF2)

PGUU:

104460445(MTF2)

ACAR:

104521217(MTF2)

CPEA:

104396748(MTF2)

AVIT:

104269561(MTF2)

CVF:	104286178(MTF2)

RTD:	128913592(MTF2)

CUCA:

104055114(MTF2)

TEO:	104369745(MTF2)

BRHI:

104496343(MTF2)

AAM:	106499781(MTF2)

AROW:

112961857(MTF2)

NPD:	112946153(MTF2)

TGT:	104569182(MTF2)

DNE:	112993147(MTF2)

SCAM:

104149064(MTF2)

ASN:	102380734(MTF2)

AMJ:	102570633(MTF2)

CPOO:

109306974(MTF2)

GGN:	109286841(MTF2)

PSS:	102461926(MTF2)

CMY:	102938837(MTF2)

CCAY:

125641244(MTF2)

DCC:	119860076(MTF2)

CPIC:

101933300(MTF2)

TST:	117881327(MTF2)

CABI:

116820496(MTF2)

MRV:	120370161(MTF2)

ACS:	100559589(mtf2)

ASAO:

132774167(MTF2)

PVT:	110076496(MTF2)

PBI:	103054854(MTF2)

PMUR:

107291257(MTF2)

CTIG:

120310269(MTF2)

TSR:	106544134(MTF2)

PGUT:

117677248(MTF2)

APRI:

131194628(MTF2)

PTEX:

113436137(MTF2)

NSS:	113414775(MTF2)

VKO:	123024613(MTF2)

PMUA:

114598717(MTF2)

PRAF:

128415445(MTF2)

ZVI:	118088386(MTF2)

HCG:	128323284(MTF2)

GJA:	107112257(MTF2)

STOW:

125432644(MTF2)

EMC:	129330077(MTF2)

XLA:	399117(mtf2.S) 779028(mtf2.L)

XTR:	550093(mtf2)

NPR:	108789247(MTF2)

RTEM:

120945680(MTF2)

BBUF:

120979551(MTF2)

BGAR:

122944215(MTF2)

MUO:	115471720(MTF2)

GSH:	117346758(MTF2)

DRE:	692292(mtf2)

SRX:	107716938(mtf2) 107743365

SANH:

107658141 107700534(mtf2)

SGH:	107568093 107588889(mtf2)

CCAR:

109068535 109099686(mtf2)

CAUA:

113045646(mtf2)

CGIB:

127951568

PTET:

122328448(mtf2)

LROH:

127154771(mtf2)

OMC:	131532870(mtf2)

PPRM:

120483008(mtf2)

RKG:	130094488(mtf2)

MAMB:

125250079(mtf2)

CIDE:

127523456

MASI:

127441684 127442436

TROS:

130554794(mtf2)

TDW:	130418295(mtf2)

MANU:

129442502(mtf2)

IPU:

108280479

IFU:	128624070(mtf2)

PHYP:

113546356(mtf2)

SMEO:

124402710(mtf2)

TFD:	113650097(mtf2)

TVC:	132844133(mtf2)

AMEX:

103032496(mtf2)

CMAO:

118797405(mtf2)

EEE:	113591490(mtf2)

CHAR:

105893800(mtf2)

TRU:	101078648(mtf2)

TFS:	130539444(mtf2)

LCO:	104920941(mtf2)

TBEN:

117488766(mtf2)

CGOB:

115022945(mtf2)

PGEO:

117462424(mtf2)

GACU:

117545546(mtf2)

EMAC:

134866200(mtf2)

ELY:	117272290(mtf2)

EFO:	125902578(mtf2)

PLEP:

121951055(mtf2)

SLUC:

116048790(mtf2)

ECRA:

117954196(mtf2)

ESP:	116699339(mtf2)

PFLV:

114565573(mtf2)

GAT:	120816226(mtf2)

PPUG:

119209883(mtf2)

AFB:	129114518(mtf2)

CLUM:

117746490(mtf2)

PSWI:

130198314(mtf2)

MSAM:

119902269(mtf2)

SCHU:

122887271(mtf2)

CUD:	121519845(mtf2)

ALAT:

119010508(mtf2)

MZE:	101468650(mtf2)

ONL:	100697914(mtf2)

OAU:	116328068(mtf2)

OLA:	101161190(mtf2)

OML:	112144240(mtf2)

CSAI:

133452899(mtf2)

XMA:	102229753(mtf2)

XCO:	114146606(mtf2)

XHE:	116721761(mtf2)

PRET:

103479123(mtf2)

PFOR:

103149533(mtf2)

PLAI:

106958291(mtf2)

PMEI:

106904252(mtf2)

GAF:	122840547(mtf2)

PPRL:

129361862(mtf2)

CVG:	107098413(mtf2)

CTUL:

119794771(mtf2)

GMU:	124870397(mtf2)

NFU:	107373124 107396371(mtf2)

KMR:	108244504(mtf2)

ALIM:

106529837(mtf2)

NWH:	119414545(mtf2)

AOCE:

111576268(mtf2)

MCEP:

125011196(mtf2)

CSEM:

103396091(mtf2)

POV:	109644497(mtf2)

SSEN:

122778108(mtf2)

HHIP:

117778246(mtf2)

HSP:	118117170(mtf2)

SMAU:

118311732(mtf2)

LCF:

108883706

SDU:	111229122(mtf2)

SLAL:

111661293(mtf2)

XGL:	120799295(mtf2)

HCQ:	109520552(mtf2)

SSCV:

125985333

SBIA:

133511215(mtf2)

PEE:	133412048(mtf2)

PTAO:

133489127(mtf2)

BPEC:

110153359(mtf2)

MALB:

109969302(mtf2)

BSPL:

114844302(mtf2)

SJO:	128368742(mtf2)

SASA:

106568979 106598921

STRU:

115156701(mtf2) 115169993

OTW:	112227094 112260278(mtf2)

OMY:	110508945 110530098(mtf2)

OGO:	124009686(mtf2)

ONE:	115103276 115114185

OKI:	109872198 109874904

OKE:	118394485 118402387(mtf2)

SALP:

111957100(mtf2) 111979073

SNH:	120020107 120055782(mtf2)

CCLU:

121535033(mtf2)

ELS:	105024029(mtf2)

SFM:	108921695(mtf2)

PKI:	111846463(mtf2)

AANG:

118229773(mtf2)

LOC:	102683256(mtf2)

PSPA:

121294170 121326883

ARUT:

117402282 117416683

LCM:	102351864(MTF2)

CMK:	103174659(mtf2)

RTP:	109931505(mtf2)

CPLA:

122554180(mtf2)

HOC:	132819170(mtf2)

LERI:

129700756(mtf2)

PMRN:

LRJ:

BFO:

BBEL:

CIN:

SCLV:

SPU:	105446473 590080

LPIC:

129277814

APLC:

110988578

AJC:

117100013

DME:	Dmel_CG5109(Pcl)

DER:

6546998

DSE:

6609736

DSI:	Dsimw501_GD11340(Dsim_GD11340)

DYA:	Dyak_GE11924

DSR:

110176348

DPO:

4804150

DPE:

6589902

DMN:	108158547 117191046

DWI:	6639815 6648738

DGR:

6559044

DMO:	Dmoj_GI18653

DAZ:

DNV:

DHE:

DVI:

BOD:

TDA:

MDE:

LCQ:

ECOE:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AAG:

AALB:

CQU:	CpipJ_CPIJ005572

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

AROA:

TCA:

DPA:

SOY:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_204497

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:

PGW:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:	111049761 120348945 120355225

HVI:

MQU:

FOC:

TPAL:

ZNE:

CSEC:

BROR:

FCD:

DPX:	DAPPUDRAFT_301671

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

LSM:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

CSCU:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

LGI:	LOTGIDRAFT_224538

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:	111123344 111125600

CANU:

OED:

MYI:

PMAX:

MMER:

DPOL:

OBI:

OSN:

LAK:	106156835 106174485

DGT:

114530343

TAD:	TRIADDRAFT_56605

» show all

Reference

PMID:11571280

Authors

O'Connell S, Wang L, Robert S, Jones CA, Saint R, Jones RS

Title

Polycomblike PHD fingers mediate conserved interaction with enhancer of zeste protein.

Journal

J Biol Chem 276:43065-73 (2001)
DOI:10.1074/jbc.M104294200

Sequence

[dme:Dmel_CG5109]

Reference

PMID:19738629

Authors

Simon JA, Kingston RE

Title

Mechanisms of polycomb gene silencing: knowns and unknowns.

Journal

Nat Rev Mol Cell Biol 10:697-708 (2009)
DOI:10.1038/nrm2763

Reference

PMID:21059868

Authors

Li X, Isono K, Yamada D, Endo TA, Endoh M, Shinga J, Mizutani-Koseki Y, Otte AP, Casanova M, Kitamura H, Kamijo T, Sharif J, Ohara O, Toyada T, Bernstein BE, Brockdorff N, Koseki H

Title

Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genes.

Journal

Mol Cell Biol 31:351-64 (2011)
DOI:10.1128/MCB.00259-10

Sequence

[mmu:17765]

LinkDB

DBGET integrated database retrieval system