KEGG ORTHOLOGY: K13140

ORTHOLOGY: K13140

Entry

K13140                      KO

Symbol

INTS3

Name

integrator complex subunit 3

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03041 Spliceosome
    K13140  INTS3; integrator complex subunit 3
Spliceosome [BR:ko03041]
Other splicing related proteins
  Proteins involved in snRNP biogenesis
   Integrator complex
    K13140  INTS3; integrator complex subunit 3

Genes

HSA:	65123(INTS3)

PTR:	457331(INTS3)

PPS:	100982754(INTS3)

GGO:	101147394(INTS3)

PON:	100171777(INTS3)

PPYG:

129009253(INTS3)

NLE:	100602032(INTS3)

HMH:	116469382(INTS3)

SSYN:

134734336(INTS3)

MCC:	715645(INTS3)

MCF:	101925499(INTS3)

MTHB:

126933081

MNI:	105497948(INTS3)

CSAB:

103223949(INTS3)

CATY:

105593470(INTS3)

PANU:

103876130(INTS3)

TGE:	112621360(INTS3)

MLEU:

105554048(INTS3)

RRO:	104663521(INTS3)

RBB:

108518849

PTEH:

111543700(INTS3)

CANG:

105501985(INTS3)

CJC:	100396734(INTS3)

SBQ:	101043937(INTS3)

CIMI:

108292431(INTS3)

ANAN:

105733640(INTS3)

CSYR:

103261741(INTS3)

MMUR:

105885914(INTS3)

LCAT:

123634001(INTS3)

PCOQ:

105821736(INTS3)

OGA:	100954890(INTS3)

MMU:	229543(Ints3)

MCAL:

110290692(Ints3)

MPAH:

110319945(Ints3)

RNO:	361988(Ints3)

MCOC:

116093215(Ints3)

ANU:	117706786(Ints3)

ASYL:

127683063(Ints3)

MUN:	110554234(Ints3)

CGE:	100768339(Ints3)

MAUA:

101826645(Ints3)

PROB:

127233039(Ints3)

PLEU:

114707879(Ints3)

MORG:

121450932(Ints3)

MFOT:

126486521

AAMP:

119801131(Ints3)

NGI:	103751757(Ints3)

HGL:	101711918(Ints3)

CPOC:

100726318(Ints3)

CCAN:

109688053(Ints3)

DORD:

105984900(Ints3)

DSP:	122109473(Ints3)

PLOP:

125359922(Ints3)

NCAR:

124992006

MMMA:

107156769(Ints3)

ITI:	101975794(Ints3)

OCU:

100342138

OPI:	101521325(INTS3)

TUP:	102497613(INTS3)

GVR:	103586355(INTS3)

CFA:	100855813(INTS3)

CLUD:

112647749(INTS3)

VVP:	112918865(INTS3)

VLG:	121489844(INTS3)

NPO:	129508694(INTS3)

AML:	100464086(INTS3)

UMR:	103668416(INTS3)

UAH:	113245331(INTS3)

UAR:	123783232(INTS3)

ELK:

111138848

LLV:

125085540

MPUF:

101688575(INTS3)

MNP:	132025954(INTS3)

MLK:	131815023(INTS3)

NVS:	122918215(INTS3)

ORO:	101383773(INTS3)

EJU:	114198611(INTS3)

ZCA:	113932793(INTS3)

MLX:	118013824(INTS3)

NSU:	110573581(INTS3)

FCA:	101101610(INTS3)

PYU:	121015693(INTS3)

PCOO:

112851727(INTS3)

PBG:	122476237(INTS3)

PVIV:

125155034(INTS3)

LRUF:

124521708

LGF:	123586673(INTS3)

AJU:

106987229

PTG:	102953714(INTS3)

PPAD:

109256313(INTS3)

PUC:

125925760

PLEZ:

122211454(INTS3)

HHV:	120221501(INTS3)

BTA:	511052(INTS3)

BOM:	102280089(INTS3)

BIU:	109554527(INTS3)

BBUB:

102397759(INTS3)

BBIS:

104987486(INTS3)

CHX:	102186171(INTS3)

OAS:	101106729(INTS3)

BTAX:

128044488(INTS3)

CSUM:

138072598(INTS3)

ODA:	120855777(INTS3)

CCAD:

122433356(INTS3)

MREE:

136145495(INTS3)

OVR:	110135663(INTS3)

MBEZ:

129540767(INTS3)

SSC:	100152330(INTS3)

CFR:	102515137(INTS3)

CBAI:

105068203(INTS3)

CDK:	105089414(INTS3)

VPC:	102537016(INTS3)

BACU:

103006203(INTS3)

BMUS:

118892806(INTS3)

LVE:	103087921(INTS3)

OOR:	101288364(INTS3)

LALB:

132513666(INTS3)

DLE:	111166968(INTS3)

PCAD:

102982338(INTS3)

PSIU:

116754106(INTS3)

NASI:

112401710(INTS3)

ECB:	100056524(INTS3)

EPZ:	103567907(INTS3)

EAI:	106846255(INTS3)

MYB:	102254782(INTS3)

MYD:	102769470(INTS3)

MMYO:

118672949(INTS3)

MLF:	102418897(INTS3)

MDT:	132221002(INTS3)

MYUM:

138995372(INTS3)

PKL:	118721105(INTS3)

EFUS:

103299026(INTS3)

MNA:	107543840(INTS3)

DRO:	112316315(INTS3)

SHON:

118990209(INTS3)

AJM:	119061776(INTS3)

PDIC:

114488742(INTS3)

PHAS:

123804474(INTS3)

MMF:	118637218(INTS3)

PPAM:

129062364(INTS3)

HAI:	109373517(INTS3)

RFQ:	117014806(INTS3)

PALE:

102879878(INTS3)

PGIG:

120592262(INTS3)

PVP:	105306155(INTS3)

RAY:	107509097(INTS3)

MJV:	108397229(INTS3)

TOD:	119237258(INTS3)

SARA:

101548077(INTS3)

SFUM:

130032149(INTS3)

SETR:

126020692(INTS3)

LAV:	100672252(INTS3)

TMU:

101345759

ETF:	101652460(INTS3)

DNM:	101429597(INTS3)

MDO:	100014872(INTS3)

GAS:	123244161(INTS3)

SHR:	100921790(INTS3)

AFZ:

127559881

PCW:	110211997(INTS3)

TVP:	118846645(INTS3)

PBRV:

138153695(INTS3)

OAA:	114808015(INTS3)

TACU:

119947359(INTS3)

GGA:	771890(INTS3)

PCOC:

116239590(INTS3)

MGP:	100542915 104913639

CJO:	107324376(INTS3)

TPAI:

128078797(INTS3)

LMUT:

125685923(INTS3)

NMEL:

110387911(INTS3)

APLA:

119713818(INTS3)

ACYG:

106049111(INTS3)

CATA:

118258597(INTS3)

AFUL:

116499806(INTS3)

TGU:	100219671(INTS3)

LSR:	110476851(INTS3)

SCAN:

115485044(INTS3)

PMOA:

120502622(INTS3)

OTC:	121335664(INTS3)

PRUF:

121353524(INTS3)

ATRC:

139585068(INTS3)

GFR:	102035369(INTS3)

OMA:	130263480(INTS3)

PHI:	102111670(INTS3)

PMAJ:

107214645(INTS3)

CCAE:

111939527(INTS3)

CBRC:

103619616(INTS3)

ACOE:

138098700(INTS3)

ZAB:	102071270(INTS3)

ZLE:	135457939(INTS3)

SVG:	106862315(INTS3)

MMEA:

130587041(INTS3)

HRT:	120764266(INTS3)

SATI:

136372877(INTS3)

CCIC:

134055172(INTS3)

FPG:	101924271(INTS3)

FCH:	102050782(INTS3)

CCRI:

104161947(INTS3)

NNT:	104406546(INTS3)

SHAB:

115602752(INTS3)

ACUN:

113488639(INTS3)

TALA:

116960564(INTS3)

ACHC:

115345296(INTS3)

HALD:

104318052(INTS3)

HLE:	104830558(INTS3)

AGEN:

126041368

HHAR:

128145915(INTS3)

GCL:

127026810

CSTI:

104560112(INTS3)

MNB:	103767923(INTS3)

DPUB:

104304313(INTS3)

PPUS:

135192782(INTS3)

AVIT:

104273209(INTS3)

EGZ:	104122992(INTS3)

NNI:	104018279(INTS3)

PCRI:

104032230(INTS3)

PADL:

103915414(INTS3)

AFOR:

103893466(INTS3)

FGA:	104076270(INTS3)

GSTE:

104258154(INTS3)

CBOY:

140644195(INTS3)

CLV:	102097178(INTS3)

PLET:

104621786(INTS3)

EHS:	104507259(INTS3)

CUCA:

104056855(INTS3)

TEO:	104373915(INTS3)

BREG:

104642282(INTS3)

OHA:	104327399(INTS3)

CPEA:

104395912(INTS3)

CVF:	104291254(INTS3)

RTD:	128900937(INTS3)

CRID:

134525820(INTS3)

AAM:	106484293(INTS3)

AROW:

112973234(INTS3)

NPD:	112954121(INTS3)

TGT:

104567386

DNE:	112994196(INTS3)

SCAM:

104141361(INTS3)

ASN:	102373162(INTS3)

AMJ:	102572086(INTS3)

CPOO:

109324686(INTS3)

GGN:	109300893(INTS3)

CMY:	102939005(INTS3)

CCAY:

125625708(INTS3)

DCC:	119847632(INTS3)

CPIC:

101949867(INTS3)

TST:	117888566(INTS3)

CABI:

116832718(INTS3)

MRV:	120390053(INTS3)

ACS:

103282698

ASAO:

132764131(INTS3)

PVT:	110088493(INTS3)

SUND:

121915245(INTS3)

PBI:

103049761

PMUR:

107285180(INTS3)

CTIG:

120317012(INTS3)

TSR:	106555828(INTS3)

PGUT:

117658096(INTS3)

APRI:

131186706(INTS3)

VKO:	123019733(INTS3)

PMUA:

114586215(INTS3)

PRAF:

128403686(INTS3)

ZVI:	118075731(INTS3)

HCG:	128337013(INTS3)

GJA:	107110906(INTS3)

STOW:

125436402(INTS3)

EMC:	129340335(INTS3)

XLA:	108700430(ints3.S) 495409(ints3.L)

XTR:	101733079(ints3)

NPR:	108800380(INTS3)

RTEM:

120920613(INTS3)

BBUF:

120982460(INTS3)

PWL:	138268485(INTS3)

MUO:	115457808(INTS3)

GSH:	117350588(INTS3)

DRE:	560575(ints3)

SRX:	107731564 107754816

SANH:

107677482 107694364

SGH:	107584314 107595584

CCAR:

109110835 109111121

CAUA:

113090775 113119505

CGIB:

127935615 127979134

PTET:

122323962(ints3)

LROH:

127181865(ints3)

OMC:	131526131(ints3)

PPRM:

120485227(ints3)

RKG:	130087945(ints3)

MAMB:

125274734(ints3)

CIDE:

127501239

CERY:

137037308(ints3)

MASI:

127420912 127425578

TROS:

130567200(ints3)

MANU:

129455435(ints3)

PDAB:

135783109(ints3)

IPU:

108273209

IFU:	128615880(ints3)

PHYP:

113543867(ints3)

SMEO:

124382136(ints3)

TFD:	113659009(ints3)

TVC:	132842735(ints3)

CGAR:

128515902(ints3)

NGRA:

132870775(ints3)

TRN:	134328566(ints3)

AMEX:

103032872(ints3)

CMAO:

118802168(ints3)

EEE:	113583422(ints3)

CHAR:

105893761(ints3)

SPIL:

134072606(ints3)

TRU:	101067561(ints3)

TFS:	130518416(ints3)

TNG:	GSTEN00008016G001

LCO:	104938058(ints3)

TBEN:

117474438(ints3) 117475951

EMAC:

134875247(ints3)

ELY:	117264004(ints3)

EFO:	125904852(ints3)

SLUC:

116034420(ints3) 118494551

PFLV:

114571231(ints3)

GAT:	120826753(ints3)

PPUG:

119219121(ints3)

AFB:	129096837(ints3)

CLUM:

117739300(ints3)

PSWI:

130198598(ints3)

CANA:

137779401(ints3)

CVE:	137889405(ints3)

MSAM:

119906943(ints3)

SCHU:

122864526(ints3)

CUD:	121524470(ints3)

SPUL:

138608761(ints3)

LMIX:

132990767(ints3)

ALAT:

119017260(ints3)

ASTR:

137607037(ints3)

MZE:	101481009(ints3)

ONL:	100708251(ints3)

OAU:	116320794(ints3)

OLA:	101171678(ints3)

OML:	112162625(ints3)

CSAI:

133461228(ints3)

XMA:	102231787(ints3)

XCO:	114155761(ints3)

XHE:	116731551(ints3)

PRET:

103472570(ints3)

PFOR:

103147917(ints3)

PLAI:

106951834(ints3)

PMEI:

106916121(ints3)

GAF:	122843846(ints3)

PPRL:

129353239(ints3)

CVG:	107084499(ints3)

CTUL:

119778085(ints3)

GMU:	124879307(ints3)

NFU:	107394484(ints3)

KMR:	108243875(ints3)

ALIM:

106527526(ints3)

NWH:	119425833(ints3)

AOCE:

111575230 129350729

EJA:	138209896(ints3)

BFRE:

138637157(ints3)

MCEP:

125020247(ints3)

CSEM:

103393747(ints3)

POV:	109643496(ints3)

SSEN:

122764878(ints3)

SSOE:

131447465(ints3)

HHIP:

117770789(ints3)

HSP:	118124460(ints3)

PPLT:

128461942(ints3)

SMAU:

118291777(ints3)

LCF:

108889904

SDU:	111223304(ints3)

SLAL:

111659064(ints3)

XGL:	120786601(ints3)

HCQ:	109515200(ints3)

SSCV:

125987389(ints3)

SBIA:

133503153(ints3)

PEE:	133395763(ints3)

PTAO:

133470955(ints3)

BPEC:

110172358(ints3)

ENY:	140362277(ints3)

MALB:

109972524(ints3)

BSPL:

114865547(ints3)

SJO:	128374540(ints3)

GMH:	115535399(ints3)

SASA:

106569880 106588323

STRU:

115173622 115175844

OTW:	112229738 112232178

OMY:	110488278 110496298

OGO:	124013124 124043473

ONE:	115128450 115131550

OKI:	109907463 116353403

OKE:	118398109 118399382

OMM:	135549904 135552153

OCLA:

139373501 139392294

SALP:

111955032 111955890

SNH:	120022589 120027122

CCLU:

121571779 121586903

ELS:	105012682(ints3)

OEP:	134041080(ints3)

SFM:	108941870(ints3)

PKI:	111838474(ints3)

AANG:

118225133 118233464

AROT:

135260400 135264300

CCOG:

133130622 133136784

LOC:	102686584(ints3)

PSPA:

121309919(ints3)

ARUT:

117395404 117395405

PSEX:

120538268(ints3)

LCM:	102361470(INTS3)

RTP:	109923325(ints3)

CPLA:

122544762(ints3)

PMRN:

116942042(INTS3)

LRJ:	133343710(INTS3)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

DME:	Dmel_CG17665(IntS3)

DER:

6543033

DSE:

6620745

DSI:	Dsimw501_GD27614(Dsim_GD27614)

DYA:	Dyak_GE11342

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI18256

DAZ:

108610089

DNV:

108649544

DHE:

111594727

DVI:	6629177(IntS3)

CCAT:

BOD:

BDR:

RZE:

AOQ:

ALUD:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

CVJ:	135950022(IntS3)

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

AALI:

ACOS:

AAG:

ASUA:

CQU:	CpipJ_CPIJ008133

CBRI:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:	114876225 114876511

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

COBS:

TLN:	139819563(Ints3)

HST:

DQU:

CFO:

FEX:

PMEC:

LHU:	105678294(IntS3)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:	100114165(Ints3) 100116508

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:	124221387(IntS3)

NFB:

NLO:

NVG:

AROA:

TCA:

TMOL:

138137259(IntS3)

DPA:

109542358

ESIM:

136414401(IntS3)

EFOR:

136346192(IntS3)

SOY:

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_204570

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

137923162(IntS3)

PRAP:

PBX:

PNAP:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CSTB:

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:	126908808 126908809

BTAB:

109038831

DCI:

103512074

CLEC:

106663903

HHAL:

106679601(IntS3)

NLU:	111046970 120352948

HVI:

124365845

MQU:

129003836

PHU:	Phum_PHUM244110

FOC:

TPAL:

ZNE:

CSEC:

PAME:

138710343(IntS3)

SGRE:

126281554

BROR:

134534943

IEL:

124167246

HAMR:

139695339(IntS3)

FCD:

110853887

DPX:	DAPPUDRAFT_306579

DMK:

116931037

DPZ:

124349226

AFRA:

136031258

PVM:	113826738(IntS3)

PJA:

122261395

PCHN:

125042978

HAME:

121874997

PCLA:

123765242(IntS3)

CQD:	128686193(IntS3)

PTRU:

123516314

ESN:

127003736

MNZ:	135215465 135215841

MRJ:	136843426(IntS3)

PORN:

139755405(IntS3)

HAZT:

108676217

EAF:

111695365

LSM:	121126121(IntS3)

TCF:

PPOI:

ISC:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

CVS:	136985575(IntS3)

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_Y92H12A.4(ints-3)

CBR:

CBG_22280

CRQ:	GCK72_001243

NAI:	NECAME_04284

BMY:	BM_BM7185(Bm7185)

LOA:	LOAG_18062

TSP:

Tsp_06451

LGI:	LOTGIDRAFT_140883

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

SMM:	Smp_169520

OVI:	T265_14119

EGL:

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:	130636533 130638489

RES:

135687318

TAD:	TRIADDRAFT_11602

AQU:

100639176

ATH:	AT4G14590(emb2739)

ALY:

110226674

CRB:

17880667

CSAT:

104718974 104723741 104732183

EUS:	EUTSA_v10017599mg EUTSA_v10027440mg

BRP:

103857544

BNA:	106402340 106437830

BOE:

106328581

RSZ:	108847051 108847062

THJ:

104800445

CPAP:

110820949

CIT:

102611444

CIC:	CICLE_v10018312mg

PVY:

MINC:

TCC:

GRA:

GHI:	107959286 121217626

GAB:

HSYR:

DZI:

EGR:

RARG:

GMX:

PVU:

VRA:

VAR:	108321966 108345145 128193566 128193651

VUN:

CCAJ:

APRC:

MTR:

TPRA:

CAM:

PSAT:

VVO:

LJA:

ADU:

AIP:

AHF:	112709731 112775752 112793706

LANG:

109335119

PCIN:

129303933

QSA:	O6P43_032462

FVE:

101297515

AANS:

126797003 126799298

RCN:	112172378 112190382

PPER:

PMUM:

PAVI:

PDUL:

MDM:	103402120 103454082

MSYL:

126589735 126601826

PXB:	103936836 103936838 103947943

PCOX:

137745688

ZJU:

107410736

MNT:	21383927 21385687

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

MEAN:

HBR:

MESC:

POP:

PEU:

PALZ:

PNZ:

JRE:

CILL:

CAVE:

AGLU:

QSU:	136061008 136066386

QLO:

TWL:

VVI:

VRI:

SLY:

SPEN:

SOT:

SSTN:

SDUL:

CANN:

LBB:

NTA:

NSY:

NTO:

NAU:

INI:

ITR:	116016815 116024029

SIND:

OEU:

EGT:

SSPL:

SMIL:

SHIS:

APAN:

HAN:

ECAD:

LSV:

CCAV:

DCR:

CSIN:

RVL:

AEW:

DLT:

BVG:

SOE:

CQI:

ATRI:

NNU:

MING:

TSS:	122648739 122648872

PSOM:

113274811 113309644 113321656

OSA:

OBR:

OGL:

BDI:

ATS:

TDC:	119283579 119292574

TAES:

123086571 123090019 123096382

TUA:

LPER:

SBI:

ZMA:

MFLO:

SITA:

SVS:

PVIR:

PHAI:

PAUA:

PDA:

EGU:

MUS:

ZOF:	121967203 122050636 122052406

DCT:

110104804

PEQ:

110025735

AOF:	109823467 109830354

ACAK:

137944684

NCOL:

116264456

ATR:

18431216

SMO:	SELMODRAFT_102541 SELMODRAFT_53489

PPP:

112293589

MBR:	MONBRDRAFT_31905

SRE:	PTSG_09149

DDI:	DDB_G0268706(ints3)

DPP:	DICPUDRAFT_157628

DFA:	DFA_08453(ints3)

ACAN:

ACA1_333360

TET:	TTHERM_00772000

PIF:	PITG_20205

PSOJ:

PHYSODRAFT_544993

SPAR:

SPRG_07979

NGR:	NAEGRDRAFT_77760

GTT:	GUITHDRAFT_66311

» show all

Reference

PMID:19605351

Authors

Li Y, Bolderson E, Kumar R, Muniandy PA, Xue Y, Richard DJ, Seidman M, Pandita TK, Khanna KK, Wang W

Title

HSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response.

Journal

J Biol Chem 284:23525-31 (2009)
DOI:10.1074/jbc.C109.039586

Sequence

[hsa:65123]

Reference

PMID:19683501

Authors

Huang J, Gong Z, Ghosal G, Chen J

Title

SOSS complexes participate in the maintenance of genomic stability.

Journal

Mol Cell 35:384-93 (2009)
DOI:10.1016/j.molcel.2009.06.011

Sequence

[hsa:65123]

LinkDB

DBGET integrated database retrieval system