REACTION: R03866
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Entry
R03866 Reaction
Name
(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (20-hydroxylating)
Definition
Leukotriene B4 + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 20-OH-Leukotriene B4 + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C02165
+
C03024
+
C00007
<=>
C04853
+
C03161
+
C00001
Comment
CYP4F2/3
Reaction class
RC00797
C02165_C04853
Enzyme
1.14.14.94
Pathway
rn00590
Arachidonic acid metabolism
Orthology
K17726
phylloquinone omega-hydroxylase / docosahexaenoic acid omega-hydroxylase / leukotriene-B4 20-monooxygenase [EC:
1.14.14.78
1.14.14.79
1.14.14.94
]
Other DBs
RHEA:
22179
LinkDB
All DBs
RCLASS: RC00797
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Entry
RC00797 RClass
Definition
C1a-C1b:*-O1a:C1b-C1b
Reactant pair
C00219_C14748
C00249_C18218
C00510_C21005
C00712_C19616
C00756_C01387
C01779_C21883
C02050_C21006
C02165_C04853
C03577_C05952
C06142_C21390
C06429_C20855
C07185_C16650
C08281_C19623
C08491_C21385
C19418_C19620
C19621_C19622
C21509_C21696
Related class
DB search
Reaction
R02879
R03866
R04256
R07041
R08326
R09451
R09452
R09453
R09454
R09461
R10795
R10999
R11000
R11446
R11448
R11806
R12070
Enzyme
1.14.13.34
1.14.13.228
1.14.13.230
1.14.14.48
1.14.14.74
1.14.14.79
1.14.14.80
1.14.14.94
1.14.14.129
1.14.14.-
1.14.15.3
1.14.-.-
Pathway
rn00073
Cutin, suberine and wax biosynthesis
rn00590
Arachidonic acid metabolism
rn00650
Butanoate metabolism
rn01100
Metabolic pathways
rn01120
Microbial metabolism in diverse environments
rn01220
Degradation of aromatic compounds
Orthology
K07422
long-chain fatty acid omega-monooxygenase [EC:
1.14.14.80
]
K07425
long-chain fatty acid omega-monooxygenase [EC:
1.14.14.80
]
K13407
fatty acid omega-hydroxylase [EC:1.14.-.-]
K15398
fatty acid omega-hydroxylase [EC:1.14.-.-]
K15401
long-chain fatty acid omega-monooxygenase [EC:
1.14.14.80
]
K15402
fatty acid omega-hydroxylase [EC:1.14.-.-]
K17683
cytochrome P450 family 2 subfamily A6 [EC:1.14.14.-]
K17709
cytochrome P450 family 2 subfamily B6 [EC:1.14.14.-]
K17719
cytochrome P450 family 2 subfamily C9 [EC:
1.14.14.51
1.14.14.52
1.14.14.53
1.14.14.-]
K17726
phylloquinone omega-hydroxylase / docosahexaenoic acid omega-hydroxylase / leukotriene-B4 20-monooxygenase [EC:
1.14.14.78
1.14.14.79
1.14.14.94
]
K20495
long-chain fatty acid omega-monooxygenase [EC:
1.14.14.80
]
K20769
fatty acid omega-hydroxylase [EC:1.14.-.-]
K21317
butane monooxygenase alpha subunit [EC:
1.14.13.230
]
K21318
butane monooxygenase beta subunit [EC:
1.14.13.230
]
K21319
butane monooxygenase gamma subunit [EC:
1.14.13.230
]
K21320
butane monooxygenase reductase
K21321
butane monooxygenase regulatory protein
K21322
butane monooxygenase hypothetical assembly protein
DBGET
integrated database retrieval system
