KEGG   REACTION: R03866
Entry
R03866                      Reaction                               
Name
(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (20-hydroxylating)
Definition
Leukotriene B4 + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 20-OH-Leukotriene B4 + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C02165 + C03024 + C00007 <=> C04853 + C03161 + C00001
Comment
CYP4F2/3
Reaction class
RC00797  C02165_C04853
Enzyme
1.14.14.94
Pathway
rn00590  Arachidonic acid metabolism
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.94
     R03866  Leukotriene B4 + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 20-OH-Leukotriene B4 + [Oxidized NADPH---hemoprotein reductase] + H2O
Orthology
K17726  phylloquinone omega-hydroxylase / docosahexaenoic acid omega-hydroxylase / leukotriene-B4 20-monooxygenase [EC:1.14.14.78 1.14.14.79 1.14.14.94]
Other DBs
RHEA: 22179
LinkDB

KEGG   RCLASS: RC00797
Entry
RC00797                     RClass                                 
Definition
C1a-C1b:*-O1a:C1b-C1b
Reactant pair
C00219_C14748    C00249_C18218    C00510_C21005
C00712_C19616    C00756_C01387    C01779_C21883
C02050_C21006    C02165_C04853    C03577_C05952
C06142_C21390    C06429_C20855    C07185_C16650
C08281_C19623    C08491_C21385    C19418_C19620
C19621_C19622    C21509_C21696
Related class
Reaction
R02879 R03866 R04256 R07041 R08326 R09451 R09452 R09453
R09454 R09461 R10795 R10999 R11000 R11446 R11448 R11806
R12070
Enzyme
1.14.13.34      1.14.13.228     1.14.13.230     1.14.14.48      
1.14.14.74      1.14.14.79      1.14.14.80      1.14.14.94      
1.14.14.129     1.14.14.-       1.14.15.3       1.14.-.-
Pathway
rn00073  Cutin, suberine and wax biosynthesis
rn00590  Arachidonic acid metabolism
rn00650  Butanoate metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Orthology
K07422  long-chain fatty acid omega-monooxygenase [EC:1.14.14.80]
K07425  long-chain fatty acid omega-monooxygenase [EC:1.14.14.80]
K13407  fatty acid omega-hydroxylase [EC:1.14.-.-]
K15398  fatty acid omega-hydroxylase [EC:1.14.-.-]
K15401  long-chain fatty acid omega-monooxygenase [EC:1.14.14.80]
K15402  fatty acid omega-hydroxylase [EC:1.14.-.-]
K17683  cytochrome P450 family 2 subfamily A6 [EC:1.14.14.-]
K17709  cytochrome P450 family 2 subfamily B6 [EC:1.14.14.-]
K17719  cytochrome P450 family 2 subfamily C9 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.-]
K17726  phylloquinone omega-hydroxylase / docosahexaenoic acid omega-hydroxylase / leukotriene-B4 20-monooxygenase [EC:1.14.14.78 1.14.14.79 1.14.14.94]
K20495  long-chain fatty acid omega-monooxygenase [EC:1.14.14.80]
K20769  fatty acid omega-hydroxylase [EC:1.14.-.-]
K21317  butane monooxygenase alpha subunit [EC:1.14.13.230]
K21318  butane monooxygenase beta subunit [EC:1.14.13.230]
K21319  butane monooxygenase gamma subunit [EC:1.14.13.230]
K21320  butane monooxygenase reductase
K21321  butane monooxygenase regulatory protein
K21322  butane monooxygenase hypothetical assembly protein

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