KEGG   REACTION: R06525
Entry
R06525                      Reaction                               
Name
sphinganine,ferrocytochrome b5:oxygen oxidoreductase (C4-hydroxylating)
Definition
Sphinganine + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Phytosphingosine + 2 Ferricytochrome b5 + H2O
Equation
C00836 + 2 C00999 + C00007 + 2 C00080 <=> C12144 + 2 C00996 + C00001
Reaction class
RC00773  C00836_C12144
Enzyme
1.14.18.5
Pathway
rn00600  Sphingolipid metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.18  With another compound as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.18.5
     R06525  Sphinganine + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Phytosphingosine + 2 Ferricytochrome b5 + H2O
Orthology
K04713  sphinganine C4-monooxygenase [EC:1.14.18.5]
Other DBs
RHEA: 33522
LinkDB

KEGG   RCLASS: RC00773
Entry
RC00773                     RClass                                 
Definition
C1b-C1c:*-O1a:C1b+C1c-C1b+C1c
Reactant pair
C00062_C18473    C00187_C05502    C00187_C13550
C00836_C12144    C01259_C03793    C01789_C15795
C02188_C22076    C06656_C06657    C07185_C16651
C12126_C12145    C15485_C15500    C15501_C15502
C15613_C15614    C15785_C15796    C15786_C15797
C15787_C15798    C15789_C15790    C16494_C16495
C16497_C16498    C20649_C20661
Related class
Reaction
R02723 R03451 R05466 R06525 R06526 R07185 R07207 R07374
R07430 R07445 R07452 R07453 R07454 R08134 R08138 R08327
R09363 R10522 R12315 R12826
Enzyme
1.14.11.8       1.14.11.21      1.14.11.24      1.14.11.41      
1.14.11.42      1.14.11.63      1.14.13.-       1.14.14.25      
1.14.14.178     1.14.14.-       1.14.15.6       1.14.15.44      
1.14.18.5       1.17.99.3
Pathway
rn00120  Primary bile acid biosynthesis
rn00140  Steroid hormone biosynthesis
rn00310  Lysine degradation
rn00331  Clavulanic acid biosynthesis
rn00600  Sphingolipid metabolism
rn00905  Brassinosteroid biosynthesis
rn00981  Insect hormone biosynthesis
rn00982  Drug metabolism - cytochrome P450
rn00999  Biosynthesis of various plant secondary metabolites
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K00474  trimethyllysine dioxygenase [EC:1.14.11.8]
K00498  cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
K04713  sphinganine C4-monooxygenase [EC:1.14.18.5]
K07440  cholesterol 24-hydroxylase [EC:1.14.14.25]
K09587  steroid 22S-hydroxylase [EC:1.14.14.178]
K10721  3-dehydro-2,22-dideoxyecdysone 22-hydroxylase [EC:1.14.15.44]
K12639  steroid 22S-hydroxylase [EC:1.14.14.178]
K12675  clavaminate synthase [EC:1.14.11.21]
K17683  cytochrome P450 family 2 subfamily A6 [EC:1.14.14.-]
K18054  2'-deoxymugineic-acid 2'-dioxygenase / mugineic-acid 3-dioxygenase [EC:1.14.11.24 1.14.11.25]

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