KEGG   PATHWAY: ani00564
Entry
ani00564                    Pathway                                
Name
Glycerophospholipid metabolism - Aspergillus nidulans
Class
Metabolism; Lipid metabolism
Pathway map
ani00564  Glycerophospholipid metabolism
ani00564

Module
ani_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:ani00564]
ani_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:ani00564]
ani_M00093  Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:ani00564]
Other DBs
GO: 0006650
Organism
Aspergillus nidulans [GN:ani]
Gene
ANIA_00351  glycerol-3-phosphate dehydrogenase (NAD(+)) gfdA [KO:K00006] [EC:1.1.1.8]
ANIA_06792  glycerol-3-phosphate dehydrogenase (NAD(+)) gfdB [KO:K00006] [EC:1.1.1.8]
ANIA_01396  glycerol-3-phosphate dehydrogenase [KO:K00111] [EC:1.1.5.3]
ANIA_05599  hypothetical protein [KO:K13507] [EC:2.3.1.15 2.3.1.42]
ANIA_06139  1-acylglycerol-3-phosphate O-acyltransferase SLC1 [KO:K13509] [EC:2.3.1.51]
ANIA_06530  lysophospholipid acyltransferase [KO:K13519] [EC:2.3.1.51 2.3.1.23 2.3.1.-]
ANIA_01713  hypothetical protein [KO:K14674] [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
ANIA_06345  lysophosphatidic acid acyltransferase LOA1 [KO:K22831] [EC:2.3.1.51]
ANIA_05379  hypothetical protein [KO:K06123] [EC:1.1.1.101]
ANIA_10875  hypothetical protein [KO:K06123] [EC:1.1.1.101]
ANIA_00802  phosphatidate phosphatase PAH1 [KO:K15728] [EC:3.1.3.4]
ANIA_01671  hypothetical protein [KO:K18693] [EC:3.6.1.75 3.1.3.4]
ANIA_02124  hypothetical protein [KO:K18693] [EC:3.6.1.75 3.1.3.4]
ANIA_03177  diacylglycerol kinase [KO:K16368] [EC:2.7.1.174]
ANIA_07691  protein plcB [KO:K01114] [EC:3.1.4.3]
ANIA_08546  hypothetical protein [KO:K01114] [EC:3.1.4.3]
ANIA_02336  hypothetical protein [KO:K01114] [EC:3.1.4.3]
ANIA_07334  hypothetical protein [KO:K01115] [EC:3.1.4.4]
ANIA_06712  protein pldA [KO:K01115] [EC:3.1.4.4]
ANIA_10413  hypothetical protein [KO:K01115] [EC:3.1.4.4]
ANIA_06211  protein plaA [KO:K16342] [EC:3.1.1.4]
ANIA_07792  hypothetical protein [KO:K13333] [EC:3.1.1.5]
ANIA_01675  hypothetical protein [KO:K13333] [EC:3.1.1.5]
ANIA_02481  lysophospholipase [KO:K14676] [EC:3.1.1.5]
ANIA_00137  glycerophosphocholine phosphodiesterase [KO:K18696] [EC:3.1.4.46]
ANIA_00484  hypothetical protein [KO:K01126] [EC:3.1.4.46]
ANIA_00929  hypothetical protein [KO:K00866] [EC:2.7.1.32]
ANIA_01357  choline-phosphate cytidylyltransferase [KO:K00968] [EC:2.7.7.15]
ANIA_04778  hypothetical protein [KO:K00993] [EC:2.7.8.1]
ANIA_10156  hypothetical protein [KO:K00894] [EC:2.7.1.82]
ANIA_04303  ethanolamine-phosphate cytidylyltransferase [KO:K00967] [EC:2.7.7.14]
ANIA_01376  bifunctional phosphatidyl-N-methylethanolamine N-methyltransferase/phosphatidyl-N-dimethylethanolamine N-methyltransferase [KO:K00551] [EC:2.1.1.17 2.1.1.71]
ANIA_05166  phosphatidate cytidylyltransferase [KO:K00981] [EC:2.7.7.41]
ANIA_10701  hypothetical protein [KO:K17103] [EC:2.7.8.8]
ANIA_03188  hypothetical protein [KO:K01613] [EC:4.1.1.65]
ANIA_11161  hypothetical protein [KO:K01613] [EC:4.1.1.65]
ANIA_00910  phosphatidylserine decarboxylase 1 [KO:K01613] [EC:4.1.1.65]
ANIA_02261  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase [KO:K00995] [EC:2.7.8.5]
ANIA_02008  phosphatidylglycerophosphatase [KO:K01094] [EC:3.1.3.27]
ANIA_06580  cardiolipin synthase [KO:K08744] [EC:2.7.8.41]
ANIA_04046  hypothetical protein [KO:K13535] [EC:3.1.1.-]
ANIA_00913  CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
ANIA_05914  hypothetical protein [KO:K13621]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
ani00010  Glycolysis / Gluconeogenesis
ani00260  Glycine, serine and threonine metabolism
ani00561  Glycerolipid metabolism
ani00562  Inositol phosphate metabolism
ani00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
ani00565  Ether lipid metabolism
ani00620  Pyruvate metabolism
KO pathway
ko00564   
LinkDB

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