KEGG   PATHWAY: app00630
Entry
app00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Candidatus Accumulibacter regalis
Class
Metabolism; Carbohydrate metabolism
Pathway map
app00630  Glyoxylate and dicarboxylate metabolism
app00630

Module
app_M00012  Glyoxylate cycle [PATH:app00630]
app_M00621  Glycine cleavage system [PATH:app00630]
Other DBs
GO: 0046487 0043648
Organism
Candidatus Accumulibacter regalis [GN:app]
Gene
CAP2UW1_3854  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
CAP2UW1_2035  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
CAP2UW1_3755  acetate/CoA ligase [KO:K01895] [EC:6.2.1.1]
CAP2UW1_2247  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
CAP2UW1_3850  malate synthase A [KO:K01638] [EC:2.3.3.9]
CAP2UW1_1299  malate dehydrogenase, NAD-dependent [KO:K00024] [EC:1.1.1.37]
CAP2UW1_2380  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
CAP2UW1_3105  citrate synthase I [KO:K01647] [EC:2.3.3.1]
CAP2UW1_2387  citrate synthase I [KO:K01647] [EC:2.3.3.1]
CAP2UW1_3882  citrate synthase I [KO:K01647] [EC:2.3.3.1]
CAP2UW1_3037  aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
CAP2UW1_2356  aconitate hydratase 2 [KO:K01682] [EC:4.2.1.3 4.2.1.99]
CAP2UW1_2144  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
CAP2UW1_3189  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
CAP2UW1_3463  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
CAP2UW1_3919  acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
CAP2UW1_2503  MaoC domain protein dehydratase [KO:K17865] [EC:4.2.1.55]
CAP2UW1_2501  crotonyl-CoA reductase [KO:K14446] [EC:1.3.1.85]
CAP2UW1_2499  methylmalonyl-CoA mutase, large subunit [KO:K14447] [EC:5.4.99.63]
CAP2UW1_2497  acyl-CoA dehydrogenase domain protein [KO:K14448] [EC:1.3.8.12]
CAP2UW1_2509  MaoC domain protein dehydratase [KO:K14449] [EC:4.2.1.148]
CAP2UW1_2498  MaoC domain protein dehydratase [KO:K14449] [EC:4.2.1.148]
CAP2UW1_2508  HpcH/HpaI aldolase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
CAP2UW1_1136  acetyl-CoA carboxylase, biotin carboxylase [KO:K01965] [EC:6.4.1.3]
CAP2UW1_1137  carboxyl transferase [KO:K01966] [EC:6.4.1.3 2.1.3.15]
CAP2UW1_1139  methylmalonyl-CoA mutase, large subunit [KO:K01847] [EC:5.4.99.2]
CAP2UW1_2032  FAD linked oxidase domain protein [KO:K00104] [EC:1.1.99.14]
CAP2UW1_2033  FAD linked oxidase domain protein [KO:K11472] [EC:1.1.99.14]
CAP2UW1_2034  protein of unknown function DUF224 cysteine-rich region domain protein [KO:K11473] [EC:1.1.99.14]
CAP2UW1_2325  Catalase domain protein [KO:K03781] [EC:1.11.1.6]
CAP2UW1_4209  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [KO:K00018] [EC:1.1.1.29]
CAP2UW1_1172  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
CAP2UW1_1528  HAD-superfamily hydrolase, subfamily IA, variant 1 [KO:K01091] [EC:3.1.3.18]
CAP2UW1_0825  Ribulose-bisphosphate carboxylase [KO:K01601] [EC:4.1.1.39]
CAP2UW1_0248  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
CAP2UW1_1498  Glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
CAP2UW1_1958  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
CAP2UW1_1960  glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
CAP2UW1_1840  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
CAP2UW1_2390  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
CAP2UW1_4249  pyridine nucleotide-disulphide oxidoreductase dimerisation region [KO:K00382] [EC:1.8.1.4]
CAP2UW1_1959  glycine cleavage system H protein [KO:K02437]
CAP2UW1_0666  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
CAP2UW1_2635  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
CAP2UW1_2636  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
CAP2UW1_2071  Hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
CAP2UW1_3896  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
app00010  Glycolysis / Gluconeogenesis
app00020  Citrate cycle (TCA cycle)
app00030  Pentose phosphate pathway
app00071  Fatty acid degradation
app00230  Purine metabolism
app00250  Alanine, aspartate and glutamate metabolism
app00260  Glycine, serine and threonine metabolism
app00620  Pyruvate metabolism
app00710  Carbon fixation by Calvin cycle
app00750  Vitamin B6 metabolism
app00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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