KEGG   PATHWAY: btj00230
Entry
btj00230                    Pathway                                
Name
Purine metabolism - Burkholderia thailandensis E444
Class
Metabolism; Nucleotide metabolism
Pathway map
btj00230  Purine metabolism
btj00230

Module
btj_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:btj00230]
btj_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:btj00230]
btj_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:btj00230]
btj_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:btj00230]
btj_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:btj00230]
Other DBs
GO: 0006163 0042278
Organism
Burkholderia thailandensis E444 [GN:btj]
Gene
BTJ_1026  [KO:K00951] [EC:2.7.6.5]
BTJ_1179  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
BTJ_1251  [KO:K03651] [EC:3.1.4.53]
BTJ_1332  [KO:K01515] [EC:3.6.1.13 3.6.1.-]
BTJ_1397  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
BTJ_1433  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
BTJ_1605  cysN; sulfate adenylyltransferase, large subunit [KO:K00956] [EC:2.7.7.4]
BTJ_1606  cysD; sulfate adenylyltransferase, small subunit [KO:K00957] [EC:2.7.7.4]
BTJ_1649  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
BTJ_1684  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
BTJ_1758  purK; phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
BTJ_1759  purE; phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
BTJ_1760  purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
BTJ_1850  [KO:K01768] [EC:4.6.1.1]
BTJ_1972  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
BTJ_1991  prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
BTJ_206  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
BTJ_2092  cpdB; 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
BTJ_214  cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
BTJ_2427  [KO:K01951] [EC:6.3.5.2]
BTJ_2741  dgt; dGTPase family protein [KO:K01129] [EC:3.1.5.1]
BTJ_2915  [KO:K00760] [EC:2.4.2.8]
BTJ_2920  [KO:K00525] [EC:1.17.4.1]
BTJ_2921  [KO:K00526] [EC:1.17.4.1]
BTJ_2924  [KO:K00856] [EC:2.7.1.20]
BTJ_2967  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
BTJ_2968  [KO:K01483] [EC:4.3.2.3]
BTJ_2984  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
BTJ_3012  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
BTJ_3078  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
BTJ_3170  xdhA; xanthine dehydrogenase, small subunit [KO:K13481] [EC:1.17.1.4]
BTJ_3171  xdhB; xanthine dehydrogenase, molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
BTJ_3211  apaH; diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
BTJ_3232  [KO:K15778] [EC:5.4.2.8 5.4.2.2]
BTJ_3239  ureC; urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
BTJ_3240  ureB; urease, beta subunit [KO:K01429] [EC:3.5.1.5]
BTJ_3241  ureA; urease, gamma subunit [KO:K01430] [EC:3.5.1.5]
BTJ_3347  rdgB; non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
BTJ_3350  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
BTJ_3352  [KO:K01139] [EC:2.7.6.5 3.1.7.2]
BTJ_3377  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
BTJ_3379  add; adenosine deaminase [KO:K21053] [EC:3.5.4.2]
BTJ_3850  [KO:K00525] [EC:1.17.4.1]
BTJ_3920  [KO:K01939] [EC:6.3.4.4]
BTJ_396  cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
BTJ_412  [KO:K00957] [EC:2.7.7.4]
BTJ_4142  [KO:K16856] [EC:4.3.2.3]
BTJ_4258  [KO:K00525] [EC:1.17.4.1]
BTJ_4775  cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
BTJ_4929  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
BTJ_501  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
BTJ_5010  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
BTJ_503  guaA; GMP synthase (glutamine-hydrolyzing), N-terminal domain protein [KO:K01951] [EC:6.3.5.2]
BTJ_510  [KO:K16841] [EC:5.1.99.3]
BTJ_511  [KO:K16842] [EC:3.5.2.5]
BTJ_512  uraD; OHCU decarboxylase [KO:K13485] [EC:4.1.1.97]
BTJ_513  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
BTJ_515  allA; ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
BTJ_517  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
BTJ_5239  prs; ribose-phosphate diphosphokinase family protein [KO:K00948] [EC:2.7.6.1]
BTJ_575  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
BTJ_667  [KO:K00940] [EC:2.7.4.6]
BTJ_681  purA; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
BTJ_690  [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
BTJ_822  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
btj00030  Pentose phosphate pathway
btj00220  Arginine biosynthesis
btj00250  Alanine, aspartate and glutamate metabolism
btj00260  Glycine, serine and threonine metabolism
btj00340  Histidine metabolism
btj00630  Glyoxylate and dicarboxylate metabolism
btj00730  Thiamine metabolism
btj00740  Riboflavin metabolism
btj00790  Folate biosynthesis
KO pathway
ko00230   

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