KEGG   PATHWAY: bxe00630
Entry
bxe00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Paraburkholderia xenovorans LB400
Class
Metabolism; Carbohydrate metabolism
Pathway map
bxe00630  Glyoxylate and dicarboxylate metabolism
bxe00630

Module
bxe_M00012  Glyoxylate cycle [PATH:bxe00630]
bxe_M00621  Glycine cleavage system [PATH:bxe00630]
Other DBs
GO: 0046487 0043648
Organism
Paraburkholderia xenovorans LB400 [GN:bxe]
Gene
Bxe_A1651  isocitrate lyase [KO:K01637] [EC:4.1.3.1]
Bxe_B1085  AMP-binding enzyme [KO:K01895] [EC:6.2.1.1]
Bxe_A1862  acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
Bxe_A1395  Putative acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
Bxe_A3113  acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
Bxe_A2769  Putative acetyl-CoA synthetase and ligase [KO:K01895] [EC:6.2.1.1]
Bxe_A3573  Putative AMP-binding enzyme [KO:K01895] [EC:6.2.1.1]
Bxe_A1647  Malate synthase A [KO:K01638] [EC:2.3.3.9]
Bxe_A2223  Malate synthase G [KO:K01638] [EC:2.3.3.9]
Bxe_B2898  malate dehydrogenase (NAD) [KO:K00024] [EC:1.1.1.37]
Bxe_B2890  citrate synthase [KO:K01647] [EC:2.3.3.1]
Bxe_C0986  Putative citrate synthase [KO:K01647] [EC:2.3.3.1]
Bxe_B1134  citrate synthase [KO:K01647] [EC:2.3.3.1]
Bxe_A0781  Bifunctional --transcriptional regulator, MerR family / Citrate synthase [KO:K01647] [EC:2.3.3.1]
Bxe_A1721  Excisionase/Xis, DNA-binding protein [KO:K01647] [EC:2.3.3.1]
Bxe_A2716  Putative citrate synthase [KO:K01647] [EC:2.3.3.1]
Bxe_B2903  aconitase [KO:K01681] [EC:4.2.1.3]
Bxe_B1533  aconitase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
Bxe_B0377  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
Bxe_C0332  Thiolase [KO:K00626] [EC:2.3.1.9]
Bxe_C0915  Thiolase [KO:K00626] [EC:2.3.1.9]
Bxe_B0739  Thiolase [KO:K00626] [EC:2.3.1.9]
Bxe_C0574  Acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
Bxe_A2777  3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
Bxe_A2342  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Bxe_A2335  3-ketoacyl-CoA thiolase / acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Bxe_A2273  Thiolase [KO:K00626] [EC:2.3.1.9]
Bxe_A4255  Putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Bxe_C0281  Thiolase [KO:K00626] [EC:2.3.1.9]
Bxe_A2763  Putative SCP-x_thiolase/acetyl-CoA acetyltransferase, PaaJ-like protein [KO:K00626] [EC:2.3.1.9]
Bxe_B0354  3-oxoacyl-[acyl-carrier-protein] reductase [KO:K00023] [EC:1.1.1.36]
Bxe_A2341  3-oxoacyl-[acyl-carrier-protein] reductase [KO:K00023] [EC:1.1.1.36]
Bxe_A2219  Glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
Bxe_A3978  D-lactate dehydrogenase (cytochrome) [KO:K00104] [EC:1.1.99.14]
Bxe_A3979  Putative glycolate oxidase, subunit GlcE [KO:K11472] [EC:1.1.99.14]
Bxe_A2220  Putative glycolate oxidase, subunit GlcE [KO:K11472] [EC:1.1.99.14]
Bxe_A3980  Putative glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
Bxe_A2221  Putative glycolate oxidase iron-sulfur subunit, GlcF [KO:K11473] [EC:1.1.99.14]
Bxe_B1215  Catalase [KO:K03781] [EC:1.11.1.6]
Bxe_A3986  Catalase [KO:K03781] [EC:1.11.1.6]
Bxe_B1668  Putative catalase [KO:K03781] [EC:1.11.1.6]
Bxe_A3458  Putative catalase [KO:K03781] [EC:1.11.1.6]
Bxe_B1490  D-isomer specific 2-hydroxyacid dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
Bxe_A4269  Putative 2-hydroxyacid dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
Bxe_B1979  Putative dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
Bxe_C0770  Putative dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
Bxe_A1982  Putative 2-ketogluconate 6-phosphate reductase, TkrA [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
Bxe_A1055  Putative 2-ketogluconate reductase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
Bxe_B0983  putative 2-hydroxyacid dehydrogenase [KO:K00018] [EC:1.1.1.29]
Bxe_B2479  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
Bxe_A0462  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
Bxe_A1064  Putative haloacid dehalogenase-like hydrolase [KO:K01091] [EC:3.1.3.18]
Bxe_B2453  ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit [KO:K01601] [EC:4.1.1.39]
Bxe_B2452  ribulose 1,5-bisphosphate carboxylase small subunit [KO:K01602] [EC:4.1.1.39]
Bxe_B3001  Serine--glyoxylate transaminase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
Bxe_B0942  L-glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Bxe_A1522  L-glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Bxe_B1585  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Bxe_A3914  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Bxe_A0054  Glycine cleavage system P-protein [KO:K00281] [EC:1.4.4.2]
Bxe_A0056  Glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
Bxe_C0853  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Bxe_B0582  putative dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Bxe_A1543  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Bxe_A2810  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Bxe_A0055  Glycine cleavage H-protein [KO:K02437]
Bxe_A2460  Glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
Bxe_C0958  Hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
Bxe_A2461  Hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
Bxe_C0957  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
Bxe_A2462  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
Bxe_B0704  putative 3-hydroxyisobutyrate dehydrogenase [KO:K00042] [EC:1.1.1.60]
Bxe_A2298  Glycerate kinase [KO:K00865] [EC:2.7.1.165]
Bxe_B1620  Tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
Bxe_B1486  Tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
Bxe_C1229  Tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
Bxe_C0769  Tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
Bxe_A0590  2-keto-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
Bxe_A0963  fdhD; formate dehydrogenase delta subunit [KO:K00126] [EC:1.17.1.9]
Bxe_B2554  formate dehydrogenase (quinone-dependent) catalytic subunit [KO:K00123] [EC:1.17.1.9]
Bxe_B2553  formate dehydrogenase (quinone-dependent) catalytic subunit [KO:K00123] [EC:1.17.1.9]
Bxe_A0964  fdhA; formate dehydrogenase alpha subunit [KO:K00123] [EC:1.17.1.9]
Bxe_A0965  fdhB; formate dehydrogenase beta subunit [KO:K00124]
Bxe_B2552  formate dehydrogenase (quinone-dependent) iron-sulfur subunit [KO:K00124]
Bxe_A0966  fdhC; formate dehydrogenase gamma subunit [KO:K00127]
Bxe_B2551  formate dehydrogenase (quinone-dependent) cytochrome b subunit [KO:K00127]
Bxe_C0624  Putative esterase [KO:K01432] [EC:3.5.1.9]
Bxe_A0735  Kynurenine formamidase [KO:K07130] [EC:3.5.1.9]
Bxe_B1575  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Bxe_A4112  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Bxe_B1706  Formamidase (FmdA) [KO:K01455] [EC:3.5.1.49]
Bxe_A2941  N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Bxe_B2759  Putative oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
Bxe_B2267  acyl-CoA transferase [KO:K07749] [EC:2.8.3.16]
Bxe_B2760  Putative formyl-coenzyme A transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
bxe00010  Glycolysis / Gluconeogenesis
bxe00020  Citrate cycle (TCA cycle)
bxe00030  Pentose phosphate pathway
bxe00053  Ascorbate and aldarate metabolism
bxe00071  Fatty acid degradation
bxe00230  Purine metabolism
bxe00250  Alanine, aspartate and glutamate metabolism
bxe00260  Glycine, serine and threonine metabolism
bxe00620  Pyruvate metabolism
bxe00710  Carbon fixation by Calvin cycle
bxe00750  Vitamin B6 metabolism
bxe00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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