KEGG   PATHWAY: bxe00230
Entry
bxe00230                    Pathway                                
Name
Purine metabolism - Paraburkholderia xenovorans LB400
Class
Metabolism; Nucleotide metabolism
Pathway map
bxe00230  Purine metabolism
bxe00230

Module
bxe_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bxe00230]
bxe_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bxe00230]
bxe_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bxe00230]
bxe_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bxe00230]
bxe_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bxe00230]
bxe_M00546  Purine degradation, xanthine => urea [PATH:bxe00230]
bxe_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:bxe00230]
bxe_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:bxe00230]
Other DBs
GO: 0006163 0042278
Organism
Paraburkholderia xenovorans LB400 [GN:bxe]
Gene
Bxe_A3199  Putative ADP-ribose pyrophosphatase, MutT/nudix family [KO:K01515] [EC:3.6.1.13 3.6.1.-]
Bxe_B1518  Phosphoglucomutase, alpha-D-glucosephosphate-specific [KO:K01835] [EC:5.4.2.2]
Bxe_C0545  Phosphoglucomutase, alpha-D-glucose phosphate-specific [KO:K01835] [EC:5.4.2.2]
Bxe_A3701  phosphomannomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
Bxe_A4133  Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
Bxe_B2874  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
Bxe_A3260  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
Bxe_A0809  formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
Bxe_A3301  formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
Bxe_A2283  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
Bxe_A3936  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
Bxe_A0694  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
Bxe_A0693  5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
Bxe_A0692  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
Bxe_A0593  Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
Bxe_A0619  IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
Bxe_A4115  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
Bxe_A4055  Hypothetical protein [KO:K01081] [EC:3.1.3.5]
Bxe_A2353  3'-nucleotidase [KO:K03787] [EC:3.1.3.5 3.1.3.6]
Bxe_C1372  Conserved hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
Bxe_A2345  Protein of unknown function DUF152 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
Bxe_A0515  Putative hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
Bxe_A1706  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
Bxe_A1591  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
Bxe_A0902  Ham1-like protein [KO:K01519] [EC:3.6.1.66]
Bxe_A0950  Xanthine dehydrogenase, subunit A [KO:K13481] [EC:1.17.1.4]
Bxe_A3886  Putative xanthine dehydrogenase [KO:K13481] [EC:1.17.1.4]
Bxe_A0949  Xanthine oxidase / xanthine dehydrogenase, molybdenum binding subunit apoprotein [KO:K13482] [EC:1.17.1.4]
Bxe_A3885  xanthine dehydrogenase, molybdenum binding subunit apoprotein / Xanthine oxidase [KO:K13482] [EC:1.17.1.4]
Bxe_B1320  xanthine dehydrogenase, molybdenum binding subunit apoprotein [KO:K11177] [EC:1.17.1.4]
Bxe_B2226  xanthine dehydrogenase, molybdenum binding subunit apoprotein [KO:K11177] [EC:1.17.1.4]
Bxe_C1225  xanthine dehydrogenase, molybdenum binding subunit apoprotein [KO:K11177] [EC:1.17.1.4]
Bxe_B2225  Oxidoreductase [KO:K11178] [EC:1.17.1.4]
Bxe_C1224  putative oxidoreductase, molybdopterin binding subunit [KO:K11178] [EC:1.17.1.4]
Bxe_B1319  Oxidoreductase [KO:K11178] [EC:1.17.1.4]
Bxe_B1943  Oxidoreductase, molybdopterin-binding subunit [KO:K11178] [EC:1.17.1.4]
Bxe_B1318  2Fe-2S iron-sulfur cluster binding protein [KO:K13483]
Bxe_B2224  2Fe-2S ferredoxin [KO:K13483]
Bxe_C1223  putative oxidoreductase [KO:K13483]
Bxe_A0004  putative glutamine amidotransferase class-I [KO:K01951] [EC:6.3.5.2]
Bxe_A1708  GMP synthase (glutamine-hydrolyzing) [KO:K01951] [EC:6.3.5.2]
Bxe_A0946  guanine deaminase [KO:K01487] [EC:3.5.4.3]
Bxe_A0905  guanylate kinase [KO:K00942] [EC:2.7.4.8]
Bxe_A0521  Ribonucleoside-diphosphate reductase [KO:K00525] [EC:1.17.4.1]
Bxe_B1704  putative ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
Bxe_A0523  Ribonucleoside-diphosphate reductase [KO:K00526] [EC:1.17.4.1]
Bxe_A0361  Deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
Bxe_A0907  (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA [KO:K01139] [EC:2.7.6.5 3.1.7.2]
Bxe_A1274  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Bxe_A1370  (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA [KO:K00951] [EC:2.7.6.5]
Bxe_B0811  hypothetical protein [KO:K01768] [EC:4.6.1.1]
Bxe_A1606  Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
Bxe_A0527  Putative sugar kinase transferase, PfkB [KO:K00856] [EC:2.7.1.20]
Bxe_B2838  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
Bxe_A0947  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
Bxe_A0763  Adenylate kinase [KO:K00939] [EC:2.7.4.3]
Bxe_A1464  Putative cAMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
Bxe_A3805  Bis(5'nucleosyl)-tetraphosphatase, ApaH [KO:K01525] [EC:3.6.1.41]
Bxe_A2481  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
Bxe_A3660  sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
Bxe_A3661  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
Bxe_C0093  Putative oxidoreductase [KO:K22879] [EC:1.14.13.113]
Bxe_A2162  Putative oxidoreductase protein, TrkA domain-containing (K+ transport) [KO:K22879] [EC:1.14.13.113]
Bxe_C0114  Putative monooxygenase [KO:K22879] [EC:1.14.13.113]
Bxe_A1934  Putative transthyretin-like protein [KO:K07127] [EC:3.5.2.17]
Bxe_A1927  Uncharacterized conserved protein [KO:K13485] [EC:4.1.1.97]
Bxe_A1925  Putative hydantoin racemase [KO:K16841] [EC:5.1.99.3]
Bxe_C0738  Putative hydantoin racemase [KO:K16841] [EC:5.1.99.3]
Bxe_A1926  Putative polysaccharide deacetylase [KO:K16842] [EC:3.5.2.5]
Bxe_C1323  Allantoicase [KO:K01477] [EC:3.5.3.4]
Bxe_B2651  Allantoicase [KO:K01477] [EC:3.5.3.4]
Bxe_A0569  Allantoicase [KO:K01477] [EC:3.5.3.4]
Bxe_A1928  Allantoicase [KO:K01477] [EC:3.5.3.4]
Bxe_A0570  Ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
Bxe_A1929  Ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
Bxe_B2956  Fumarylacetoacetate hydrolase family protein [KO:K16856] [EC:4.3.2.3]
Bxe_A3369  Putative fumarylacetoacetate hydrolase family protein [KO:K16856] [EC:4.3.2.3]
Bxe_A3694  urease, Metallo peptidase, MEROPS family M38 [KO:K01428] [EC:3.5.1.5]
Bxe_A3693  Urease, beta subunit [KO:K01429] [EC:3.5.1.5]
Bxe_A3692  Urease, gamma subunit [KO:K01430] [EC:3.5.1.5]
Bxe_B1050  gamma-glutamyltransferase 2, Threonine peptidase, MEROPS family T03 [KO:K22602] [EC:3.5.1.126]
Bxe_C0748  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Bxe_A1875  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bxe00030  Pentose phosphate pathway
bxe00220  Arginine biosynthesis
bxe00250  Alanine, aspartate and glutamate metabolism
bxe00260  Glycine, serine and threonine metabolism
bxe00340  Histidine metabolism
bxe00630  Glyoxylate and dicarboxylate metabolism
bxe00730  Thiamine metabolism
bxe00740  Riboflavin metabolism
bxe00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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