KEGG   PATHWAY: cfa00190
Entry
cfa00190                    Pathway                                
Name
Oxidative phosphorylation - Canis lupus familiaris (dog)
Class
Metabolism; Energy metabolism
Pathway map
cfa00190  Oxidative phosphorylation
cfa00190

Module
cfa_M00142  NADH:ubiquinone oxidoreductase, mitochondria [PATH:cfa00190]
cfa_M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH:cfa00190]
cfa_M00146  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex [PATH:cfa00190]
cfa_M00147  NADH dehydrogenase (ubiquinone) 1 beta subcomplex [PATH:cfa00190]
cfa_M00151  Cytochrome bc1 complex respiratory unit [PATH:cfa00190]
cfa_M00152  Cytochrome bc1 complex [PATH:cfa00190]
Organism
Canis lupus familiaris (dog) [GN:cfa]
Gene
100682717  [KO:K02128]
100682783  [KO:K02131]
100682956  [KO:K03948]
100683076  [KO:K02271]
100683222  [KO:K02129]
100683682  [KO:K03955]
100683828  [KO:K00417]
100683846  NDUFB2; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial [KO:K03958]
100683951  [KO:K03949]
100684768  [KO:K03948]
100684805  ATP5ME; ATP synthase subunit e, mitochondrial [KO:K02129]
100684842  [KO:K02271]
100684983  [KO:K02271]
100684996  [KO:K02138]
100685007  [KO:K02128]
100685227  [KO:K02128]
100685720  [KO:K02131]
100686500  [KO:K02270]
100686510  [KO:K02271]
100686580  [KO:K02267]
100686889  [KO:K03948]
100687033  NDUFB6; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 [KO:K03962]
100687434  COX7B2; cytochrome c oxidase subunit 7B2, mitochondrial [KO:K02271]
100687598  ATP5MG; ATP synthase subunit g, mitochondrial [KO:K02140]
100688724  [KO:K03948]
100688835  [KO:K03949]
100689004  [KO:K08738]
100855425  [KO:K02140]
100855914  [KO:K03947]
100855975  NDUFB3; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 isoform X2 [KO:K03959]
100856334  NDUFA4; cytochrome c oxidase subunit NDUFA4 [KO:K03948]
102151342  [KO:K02138]
102151506  [KO:K03947]
102151754  [KO:K02272]
102151856  [KO:K02130]
102152234  [KO:K02153]
102152785  [KO:K02271]
102153059  [KO:K02272]
102153397  ATP5F1E; ATP synthase subunit epsilon, mitochondrial [KO:K02135]
102154025  [KO:K03945]
102154035  NDUFA1; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 [KO:K03945]
102154372  [KO:K02128]
102154486  [KO:K02140]
102154590  [KO:K03961]
102155410  [KO:K02272]
102156642  [KO:K02267]
102156968  [KO:K02266]
106557778  [KO:K03945]
106558390  [KO:K02273]
111090910  [KO:K02152]
111092022  [KO:K02130]
111096466  [KO:K03957]
119863903  [KO:K02270]
119866697  [KO:K02130]
119866701  [KO:K02140]
119868043  [KO:K02130]
119870103  [KO:K03949]
119870484  [KO:K02138]
119870901  [KO:K02267]
119874008  [KO:K03948]
403669  ATP5F1B; ATP synthase subunit beta, mitochondrial [KO:K02133] [EC:7.1.2.2]
403729  ATP6V0E1; V-type proton ATPase subunit e 1 [KO:K02153]
403820  ATP12A; potassium-transporting ATPase alpha chain 2 [KO:K01544] [EC:7.2.2.19]
404020  ATP4B; potassium-transporting ATPase subunit beta [KO:K01543] [EC:7.2.2.19]
431686  ATP4A; potassium-transporting ATPase alpha chain 1 [KO:K01542] [EC:7.2.2.19]
474483  NDUFA6; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 [KO:K03950]
474567  COX5B; cytochrome c oxidase subunit 5B [KO:K02265]
474628  ATP6V1B1; V-type proton ATPase subunit B, kidney isoform isoform X1 [KO:K02147]
474840  ATP6V1G2; V-type proton ATPase subunit G 1 [KO:K02152]
475061  ATP6V1C1; V-type proton ATPase subunit C 1 isoform X1 [KO:K02148]
475094  NDUFB9; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 isoform X1 [KO:K03965]
475121  CYC1; cytochrome c1, heme protein, mitochondrial [KO:K00413]
475199  ATP6V1F; V-type proton ATPase subunit F [KO:K02151]
475214  NDUFA5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 [KO:K03949]
475258  CYCS; cytochrome c [KO:K08738]
475322  NDUFS5; NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 [KO:K03938]
475428  NDUFA12; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 [KO:K11352]
475667  ATP6V1C2; V-type proton ATPase subunit C 2 isoform X6 [KO:K02148]
475739  COX7A2L; cytochrome c oxidase subunit 7A-related protein, mitochondrial isoform X3 [KO:K02270]
475978  NDUFS3; NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial isoform X1 [KO:K03936] [EC:7.1.1.2]
476004  NDUFV1; NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial [KO:K03942] [EC:7.1.1.2]
476040  COX8A; cytochrome c oxidase subunit 8A, mitochondrial [KO:K02273]
476372  [KO:K02130]
476503  UQCRFS1; cytochrome b-c1 complex subunit Rieske, mitochondrial [KO:K00411] [EC:7.1.1.8]
476659  NDUFA13; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 [KO:K11353]
476686  NDUFB7; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 [KO:K03963]
476722  NDUFA7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 [KO:K03951]
476735  NDUFA11; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 [KO:K03956]
476754  NDUFS7; NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial isoform X3 [KO:K03940] [EC:7.1.1.2]
476756  ATP5F1D; ATP synthase subunit delta, mitochondrial [KO:K02134]
476794  NDUFC2; NADH dehydrogenase [ubiquinone] 1 subunit C2 [KO:K03968]
477508  [KO:K02266]
477595  ATP5MC2; ATP synthase F(0) complex subunit C2, mitochondrial isoform X1 [KO:K02128]
477718  NDUFA9; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial [KO:K03953]
477740  ATP6V1E1; V-type proton ATPase subunit E 1 [KO:K02150]
477792  COX15; cytochrome c oxidase assembly protein COX15 homolog isoform X2 [KO:K02259] [EC:1.17.99.9]
477798  NDUFB8; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial [KO:K03964]
477929  ATP6V0D2; V-type proton ATPase subunit d 2 [KO:K02146]
478009  ATP5F1C; ATP synthase subunit gamma, mitochondrial isoform X1 [KO:K02136]
478032  NDUFA2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 isoform X1 [KO:K03946]
478217  SDHB; succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial [KO:K00235] [EC:1.3.5.1]
478370  COX5A; cytochrome c oxidase subunit 5A, mitochondrial [KO:K02264]
478410  ATP5PO; ATP synthase subunit O, mitochondrial [KO:K02137]
478421  NDUFV3; NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial isoform X1 [KO:K03944]
478500  PPA2; inorganic pyrophosphatase 2, mitochondrial isoform X4 [KO:K01507] [EC:3.6.1.1]
478577  NDUFB4; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 [KO:K03960]
478629  NDUFS6; NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial [KO:K03939]
478634  SDHA; succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial isoform X1 [KO:K00234] [EC:1.3.5.1]
478639  NDUFB5; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial [KO:K03961]
478807  ATP5MC3; ATP synthase F(0) complex subunit C3, mitochondrial [KO:K02128]
478880  NDUFS1; NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial isoform X1 [KO:K03934] [EC:7.1.1.2]
478981  NDUFS2; NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial isoform X1 [KO:K03935] [EC:7.1.1.2]
478983  SDHC; succinate dehydrogenase cytochrome b560 subunit, mitochondrial [KO:K00236]
479238  PPA1; inorganic pyrophosphatase [KO:K01507] [EC:3.6.1.1]
479335  NDUFS4; NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial isoform X11 [KO:K03937]
479623  COX4I1; cytochrome c oxidase subunit 4 isoform 1, mitochondrial [KO:K02263]
479685  ATP6V0D1; V-type proton ATPase subunit d 1 [KO:K02146]
479780  COX6A2; cytochrome c oxidase subunit 6A2, mitochondrial [KO:K02266]
479805  NDUFAB1; acyl carrier protein, mitochondrial [KO:K03955]
479815  UQCRC2; cytochrome b-c1 complex subunit 2, mitochondrial [KO:K00415]
479877  ATP6V0C; V-type proton ATPase 16 kDa proteolipid subunit [KO:K02155]
479887  NDUFB10; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 [KO:K03966]
480149  ATP5F1A; ATP synthase subunit alpha, mitochondrial [KO:K02132]
480204  NDUFV2; NADH dehydrogenase [ubiquinone] flavoprotein 2 [KO:K03943] [EC:7.1.1.2]
480360  ATP6V1D; V-type proton ATPase subunit D [KO:K02149]
480741  NDUFA8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 [KO:K03952]
480894  NDUFB11; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial [KO:K11351]
481033  [KO:K03945]
481359  ATP6V1E2; V-type proton ATPase subunit E 2 [KO:K02150]
481394  [KO:K01507] [EC:3.6.1.1]
481939  [KO:K02152]
482528  ATP6V0B; V-type proton ATPase 21 kDa proteolipid subunit isoform X2 [KO:K03661]
482600  [KO:K02138]
482779  ATP6V0A4; V-type proton ATPase 116 kDa subunit a [KO:K02154]
482789  ATP6V0E2; V-type proton ATPase subunit e 2 [KO:K02153]
483691  TCIRG1; V-type proton ATPase 116 kDa subunit a3 [KO:K02154]
485825  COX4I2; cytochrome c oxidase subunit 4 isoform 2, mitochondrial isoform X2 [KO:K02263]
486137  ATP6V1B2; V-type proton ATPase subunit B, brain isoform [KO:K02147]
486245  ATP6V0A2; V-type proton ATPase 116 kDa subunit a2 isoform X2 [KO:K02154]
486347  UQCR10; cytochrome b-c1 complex subunit 9 isoform X1 [KO:K00419]
486930  LHPP; phospholysine phosphohistidine inorganic pyrophosphate phosphatase isoform X3 [KO:K11725] [EC:3.6.1.1 3.1.3.-]
486953  ATP6V1H; V-type proton ATPase subunit H isoform X2 [KO:K02144]
487689  [KO:K02132]
487981  ATP6V1A; V-type proton ATPase catalytic subunit A [KO:K02145] [EC:7.1.2.2]
489515  COX10; protoheme IX farnesyltransferase, mitochondrial [KO:K02257] [EC:2.5.1.141]
490256  ATP6V1G3; V-type proton ATPase subunit G 3 [KO:K02152]
491061  ATP5MC1; ATP synthase F(0) complex subunit C1, mitochondrial [KO:K02128]
503668  COX17; cytochrome c oxidase copper chaperone [KO:K02260]
607407  NDUFA4L2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 isoform X2 [KO:K03948]
607705  ATP6V0A1; V-type proton ATPase 116 kDa subunit a1 isoform X1 [KO:K02154]
607943  NDUFC1; NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial [KO:K03967]
608048  [KO:K02130]
608244  NDUFA10; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10 isoform X1 [KO:K03954]
608455  UQCRC1; cytochrome b-c1 complex subunit 1, mitochondrial isoform X1 [KO:K00414]
608530  UQCRH; cytochrome b-c1 complex subunit 6, mitochondrial isoform X1 [KO:K00416]
609555  COX11; cytochrome c oxidase assembly protein COX11, mitochondrial [KO:K02258]
609744  UQCRQ; cytochrome b-c1 complex subunit 8 [KO:K00418]
609990  [KO:K02272]
610413  NDUFS8; NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial [KO:K03941] [EC:7.1.1.2]
610725  [KO:K02128]
611791  UQCR11; cytochrome b-c1 complex subunit 10 [KO:K00420]
612591  ATP6V1G1; V-type proton ATPase subunit G 1 [KO:K02152]
612614  COX7A1; cytochrome c oxidase subunit 7A1, mitochondrial isoform X1 [KO:K02270]
612644  [KO:K02267]
804476  ND1; NADH dehydrogenase subunit 1 [KO:K03878] [EC:7.1.1.2]
804477  ND2; NADH dehydrogenase subunit 2 [KO:K03879] [EC:7.1.1.2]
804478  COX1; cytochrome c oxidase subunit I [KO:K02256] [EC:7.1.1.9]
804479  COX2; cytochrome c oxidase subunit II [KO:K02261]
804480  COX3; cytochrome c oxidase subunit III [KO:K02262]
804481  ND3; NADH dehydrogenase subunit 3 [KO:K03880] [EC:7.1.1.2]
804482  ND4L; NADH dehydrogenase subunit 4L [KO:K03882] [EC:7.1.1.2]
804483  ND4; NADH dehydrogenase subunit 4 [KO:K03881] [EC:7.1.1.2]
804484  ND5; NADH dehydrogenase subunit 5 [KO:K03883] [EC:7.1.1.2]
804485  ND6; NADH dehydrogenase subunit 6 [KO:K03884] [EC:7.1.1.2]
804486  CYTB; cytochrome b [KO:K00412]
804487  ATP8; ATP synthase F0 subunit 8 [KO:K02125]
804488  ATP6; ATP synthase F0 subunit 6 [KO:K02126]
Compound
C00001  H2O
C00002  ATP
C00003  NAD+
C00004  NADH
C00007  Oxygen
C00008  ADP
C00009  Orthophosphate
C00013  Diphosphate
C00042  Succinate
C00080  H+
C00122  Fumarate
C00536  Triphosphate
Reference
PMID:16469879
  Authors
Sazanov LA, Hinchliffe P.
  Title
Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus.
  Journal
Science 311:1430-6 (2006)
DOI:10.1126/science.1123809
Reference
PMID:16584177
  Authors
Hinchliffe P, Carroll J, Sazanov LA.
  Title
Identification of a novel subunit of respiratory complex I from Thermus thermophilus.
  Journal
Biochemistry 45:4413-20 (2006)
DOI:10.1021/bi0600998
KO pathway
ko00190   

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