KEGG   PATHWAY: cti00630
Entry
cti00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Cupriavidus taiwanensis
Class
Metabolism; Carbohydrate metabolism
Pathway map
cti00630  Glyoxylate and dicarboxylate metabolism
cti00630

Module
cti_M00012  Glyoxylate cycle [PATH:cti00630]
cti_M00621  Glycine cleavage system [PATH:cti00630]
Other DBs
GO: 0046487 0043648
Organism
Cupriavidus taiwanensis [GN:cti]
Gene
RALTA_A0113  [KO:K00626] [EC:2.3.1.9]
RALTA_A0128  [KO:K12972] [EC:1.1.1.79 1.1.1.81]
RALTA_A0415  [KO:K01647] [EC:2.3.3.1]
RALTA_A0433  ttuC3; tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
RALTA_A0434  ttuD3; HYDROXYPYRUVATE REDUCTASE OXIDOREDUCTASE PROTEIN [KO:K11529] [EC:2.7.1.165]
RALTA_A0597  fdsG; NAD-dependent formate dehydrogenase gamma subunit [KO:K00127]
RALTA_A0598  fdsB; NAD-dependent formate dehydrogenase beta subunit [KO:K00124]
RALTA_A0599  fdsA; NAD-dependent formate dehydrogenase alpha subunit [KO:K00123] [EC:1.17.1.9]
RALTA_A0601  fdsD; NAD-dependent formate dehydrogenase delta subunit [KO:K00126] [EC:1.17.1.9]
RALTA_A0668  [KO:K01647] [EC:2.3.3.1]
RALTA_A1174  [KO:K01895] [EC:6.2.1.1]
RALTA_A1209  [KO:K00626] [EC:2.3.1.9]
RALTA_A1297  pdhL; dihydrolipoamide dehydrogenase, FAD/NAD(P)-binding, component of the 2-oxoglutarate dehydrogenase and the pyruvate dehydrogenase complexes [KO:K00382] [EC:1.8.1.4]
RALTA_A1351  phaA; Acetyl-CoA acetyltransferase (beta-ketothiolase) [KO:K00626] [EC:2.3.1.9]
RALTA_A1352  phaB1; Acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
RALTA_A1359  bktB; acetyl-CoA acetyltransferase, thiolase [KO:K00626] [EC:2.3.1.9]
RALTA_A1600  prpC; methylcitrate synthase (citrate synthase 2) [KO:K01659] [EC:2.3.3.5]
RALTA_A1758  phaB2; Acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
RALTA_A1760  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
RALTA_A1766  aceA1; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
RALTA_A1868  lpdA2; DIHYDROLIPOAMIDE DEHYDROGENASE (COMPONENT OF PYRUVATE AND 2-OXOGLUTARATE DEHYDROGENASES COMPLEXES) OXIDOREDUCTASE PROTEIN [KO:K00382] [EC:1.8.1.4]
RALTA_A2008  purU; Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
RALTA_A2028  acsA; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
RALTA_A2081  [KO:K01091] [EC:3.1.3.18]
RALTA_A2089  [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
RALTA_A2126  gltA; citrate synthase [KO:K01647] [EC:2.3.3.1]
RALTA_A2133  mdh; MALATE DEHYDROGENASE [KO:K00024] [EC:1.1.1.37]
RALTA_A2135  prpC2; methylcitrate synthase (citrate synthase 2) [KO:K01659] [EC:2.3.3.5]
RALTA_A2137  acnA2; aconitate hydratase 1 [KO:K27802]
RALTA_A2153  [KO:K05825] [EC:2.6.1.-]
RALTA_A2303  [KO:K07130] [EC:3.5.1.9]
RALTA_A2322  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
RALTA_A2416  fdhC; formate dehydrogenase, cytochrome C subunit, gamma subunit [KO:K00127]
RALTA_A2418  fdhB; FORMATE DEHYDROGENASE, IRON-SULFUR SUBUNIT [KO:K00124]
RALTA_A2419  fdhA1; formate dehydrogenase, alpha subunit (Fe4S4 domain) [KO:K00123] [EC:1.17.1.9]
RALTA_A2478  garR; tartronate semialdehyde reductase (TSAR) [KO:K00042] [EC:1.1.1.60]
RALTA_A2487  hutG1; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
RALTA_A2569  glcD; Glycolate oxidase subunit glcD [KO:K00104] [EC:1.1.99.14]
RALTA_A2571  glcE; Glycolate oxidase subunit glcE [KO:K11472] [EC:1.1.99.14]
RALTA_A2572  glcF; Glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
RALTA_A2584  [KO:K03781] [EC:1.11.1.6]
RALTA_A2770  [KO:K01091] [EC:3.1.3.18]
RALTA_A2848  [KO:K01965] [EC:6.4.1.3]
RALTA_A3052  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
RALTA_A3053  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
RALTA_A3054  glxR; tartronic semialdehyde reductase [KO:K00042] [EC:1.1.1.60]
RALTA_A3055  ttuD2; HYDROXYPYRUVATE REDUCTASE OXIDOREDUCTASE PROTEIN; tartrate degradation [KO:K11529] [EC:2.7.1.165]
RALTA_A3074  gcvT; glycine cleavage complex protein T, aminomethyltransferase, tetrahydrofolate-dependent [KO:K00605] [EC:2.1.2.10]
RALTA_A3075  gcvH; glycine cleavage complex protein H, carrier of aminomethyl moiety via covalently bound lipoyl cofactor [KO:K02437]
RALTA_A3076  gcvP; glycine cleavage complex protein P, glycine decarboxylase, PLP-dependent [KO:K00281] [EC:1.4.4.2]
RALTA_B0267  aceA2; Isocitrate lyase; Isocitrase; Isocitratase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
RALTA_B0345  katE; CATALASE HYDROPEROXIDASE HPII OXIDOREDUCTASE PROTEIN [KO:K03781] [EC:1.11.1.6]
RALTA_B0366  acnB; bifunctional aconitate hydratase 2 and 2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
RALTA_B0433  [KO:K01091] [EC:3.1.3.18]
RALTA_B0703  [KO:K12972] [EC:1.1.1.79 1.1.1.81]
RALTA_B0765  glxR; 2-hydroxy-3-oxopropionate reductase (Tartronate semialdehyde reductase) (TSAR) [KO:K00042] [EC:1.1.1.60]
RALTA_B0770  [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
RALTA_B0888  ttuD2; HYDROXYPYRUVATE REDUCTASE OXIDOREDUCTASE PROTEIN; tartrate degradation [KO:K11529] [EC:2.7.1.165]
RALTA_B0889  ttuC1; tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
RALTA_B0921  pdhD2; Dihydrolipoyl dehydrogenase, Dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
RALTA_B0925  [KO:K01895] [EC:6.2.1.1]
RALTA_B1073  [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
RALTA_B1124  eda; multifunctional: 2-keto-3-deoxygluconate 6-phosphate aldolase; 2-keto-4-hydroxyglutarate aldolase; oxaloacetate decarboxylase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
RALTA_B1319  [KO:K05825] [EC:2.6.1.-]
RALTA_B1495  fdwA; tugsten containing formate dehydrogenase alpha subunit; 2Fe-2S ferredoxin N-term domain [KO:K00123] [EC:1.17.1.9]
RALTA_B1496  fdwB; tungsten-containing formate dehydrogenase beta subunit [KO:K22515] [EC:1.17.1.9]
RALTA_B1509  frc; formyl-CoA transferase, NAD(P)-binding [KO:K07749] [EC:2.8.3.16]
RALTA_B1510  oxc; oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
RALTA_B1515  [KO:K07749] [EC:2.8.3.16]
RALTA_B1528  [KO:K00626] [EC:2.3.1.9]
RALTA_B1645  [KO:K05825] [EC:2.6.1.-]
RALTA_B1683  fdoH; Formate dehydrogenase, nitrate-inducible, iron-sulfur subunit(beta subunit) [KO:K00124]
RALTA_B1684  fdoI; formate dehydrogenase-N, cytochrome B556(Fdn) gamma subunit, nitrate-inducible [KO:K00127]
RALTA_B1693  cbbZ; phosphoglycolate phosphatase, Haloacid dehalogenase-like hydrolase domain (RUBISCO operon) [KO:K01091] [EC:3.1.3.18]
RALTA_B1701  cbbS; Ribulose bisphosphate carboxylase (RuBisCO), small subunit [KO:K01602] [EC:4.1.1.39]
RALTA_B1702  cbbL; Ribulose bisphosphate carboxylase (RuBisCO), large subunit [KO:K01601] [EC:4.1.1.39]
pRALTA_0081  [KO:K00626] [EC:2.3.1.9]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00049  L-Aspartate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C05840  Iminoaspartate
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C19838  D-erythro-3-Hydroxyaspartate
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
cti00010  Glycolysis / Gluconeogenesis
cti00020  Citrate cycle (TCA cycle)
cti00030  Pentose phosphate pathway
cti00053  Ascorbate and aldarate metabolism
cti00071  Fatty acid degradation
cti00230  Purine metabolism
cti00250  Alanine, aspartate and glutamate metabolism
cti00260  Glycine, serine and threonine metabolism
cti00270  Cysteine and methionine metabolism
cti00620  Pyruvate metabolism
cti00710  Carbon fixation by Calvin cycle
cti00750  Vitamin B6 metabolism
cti00910  Nitrogen metabolism
KO pathway
ko00630   

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