KEGG   PATHWAY: cti00230
Entry
cti00230                    Pathway                                
Name
Purine metabolism - Cupriavidus taiwanensis
Class
Metabolism; Nucleotide metabolism
Pathway map
cti00230  Purine metabolism
cti00230

Module
cti_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:cti00230]
cti_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:cti00230]
cti_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:cti00230]
cti_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:cti00230]
cti_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:cti00230]
cti_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:cti00230]
cti_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:cti00230]
Other DBs
GO: 0006163 0042278
Organism
Cupriavidus taiwanensis [GN:cti]
Gene
RALTA_A0317  prs; phosphoribosylpyrophosphate synthetase [KO:K00948] [EC:2.7.6.1]
RALTA_A0339  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
RALTA_A0457  purH; bifunctional: IMP cyclohydrolase (N-terminal); phosphoribosylaminoimidazolecarboxamide formyltransferase (C-terminal) [KO:K00602] [EC:2.1.2.3 3.5.4.10]
RALTA_A0525  purC; PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE [KO:K01923] [EC:6.3.2.6]
RALTA_A0526  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
RALTA_A0527  purK; phosphoribosylaminoimidazole carboxylase (AIR carboxylase), ATPase subunit [KO:K01589] [EC:6.3.4.18]
RALTA_A0559  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
RALTA_A0858  purD; phosphoribosylglycinamide synthetase (GAR synthetase) [KO:K01945] [EC:6.3.4.13]
RALTA_A0945  rdgB; Nucleoside-triphosphate diphosphatase [KO:K01519] [EC:3.6.1.66]
RALTA_A0950  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
RALTA_A0952  spoT; bifunctional: (p)ppGpp synthetase II; guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; putative precursor [KO:K01139] [EC:2.7.6.5 3.1.7.2]
RALTA_A0989  [KO:K13485] [EC:4.1.1.97]
RALTA_A0990  [KO:K16842] [EC:3.5.2.5]
RALTA_A0993  pucM; 5-hydroxyisourate hydrolase (HIUHase) [KO:K07127] [EC:3.5.2.17]
RALTA_A0997  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
RALTA_A0998  add; ADENOSINE DEAMINASE [KO:K21053] [EC:3.5.4.2]
RALTA_A1000  xdhB2; XANTHINE DEHYDROGENASE (SUBUNIT B) OXIDOREDUCTASE PROTEIN [KO:K13482] [EC:1.17.1.4]
RALTA_A1001  xdhA2; XANTHINE DEHYDROGENASE (SUBUNIT A) (Purine hydroxylase I) [KO:K13481] [EC:1.17.1.4]
RALTA_A1049  [KO:K01515] [EC:3.6.1.13 3.6.1.-]
RALTA_A1066  ureA; UREASE, GAMMA SUBUNIT [KO:K01430] [EC:3.5.1.5]
RALTA_A1068  ureB; UREASE, BETA SUBUNIT [KO:K01429] [EC:3.5.1.5]
RALTA_A1069  ureC; UREASE, ALPHA SUBUNIT [KO:K01428] [EC:3.5.1.5]
RALTA_A1204  [KO:K01768] [EC:4.6.1.1]
RALTA_A1259  relA; (p)ppGpp synthetase I (GTP pyrophosphokinase) [KO:K00951] [EC:2.7.6.5]
RALTA_A1348  [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
RALTA_A1379  [KO:K02083] [EC:3.5.3.9]
RALTA_A1430  [KO:K03651] [EC:3.1.4.53]
RALTA_A1453  purL; phosphoribosylformyl-glycineamide synthetase (FGAM synthetase) [KO:K01952] [EC:6.3.5.3]
RALTA_A1513  [KO:K22879] [EC:1.14.13.113]
RALTA_A1591  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
RALTA_A1607  [KO:K01951] [EC:6.3.5.2]
RALTA_A1664  guaA; GMP synthetase (glutamine aminotransferase) [KO:K01951] [EC:6.3.5.2]
RALTA_A1666  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
RALTA_A1898  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
RALTA_A1913  ndk; Nucleoside diphosphate kinase (NDK) (NDP kinase) [KO:K00940] [EC:2.7.4.6]
RALTA_A1921  surE; 5'-nucleotidase surE (Nucleoside 5'-monophosphate phosphohydrolase) [KO:K03787] [EC:3.1.3.5 3.1.3.6]
RALTA_A1936  [KO:K00525] [EC:1.17.4.1]
RALTA_A1967  ppx; EXOPOLYPHOSPHATASE PROTEIN [KO:K01524] [EC:3.6.1.11 3.6.1.40]
RALTA_A2105  purF; amidophosphoribosyltransferase (PRPP amidotransferase) [KO:K00764] [EC:2.4.2.14]
RALTA_A2364  cpsG; phosphomannomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
RALTA_A2391  apaH; Diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
RALTA_A2469  cysN; ATP-sulfurylase, subunit 1 (ATP:sulfate adenylyltransferase) [KO:K00956] [EC:2.7.7.4]
RALTA_A2470  cysD2; ATP-sulfurylase, subunit 2 (ATP:sulfate adenylyltransferase) [KO:K00957] [EC:2.7.7.4]
RALTA_A2517  purN; phosphoribosylglycinamide formyltransferase 1 [KO:K11175] [EC:2.1.2.2]
RALTA_A2537  [KO:K09913] [EC:2.4.2.1 2.4.2.2]
RALTA_A2548  [KO:K16841] [EC:5.1.99.3]
RALTA_A2552  purM; phosphoribosylaminoimidazole synthetase (AIR synthetase) [KO:K01933] [EC:6.3.3.1]
RALTA_A2600  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
RALTA_A2651  [KO:K00856] [EC:2.7.1.20]
RALTA_A2685  nrdB; ribonucleoside diphosphate reductase 1, beta subunit, ferritin-like [KO:K00526] [EC:1.17.4.1]
RALTA_A2686  nrdA; Ribonucleoside-diphosphate reductase alpha subunit [KO:K00525] [EC:1.17.4.1]
RALTA_A2693  [KO:K00760] [EC:2.4.2.8]
RALTA_A2830  xdhA1; xanthine dehydrogenase, molybdenum binding subunit [KO:K00087] [EC:1.17.1.4]
RALTA_A2892  dgt; deoxyguanosine triphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
RALTA_A3043  [KO:K02083] [EC:3.5.3.9]
RALTA_B0070  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
RALTA_B0398  [KO:K03787] [EC:3.1.3.5 3.1.3.6]
RALTA_B0475  cysN-cysC; bifunctional enzyme: ATP-sulfurylase large subunit (Sulfate adenylate transferase)(SAT) and Adenylyl-sulfate kinase (APS kinase) (ATP adenosine-5'-phosphosulfate 3'-phosphotransferase). [KO:K00955] [EC:2.7.7.4 2.7.1.25]
RALTA_B0476  cysD1; ATP-sulfurylase, subunit 2 (ATP:sulfate adenylyltransferase) [KO:K00957] [EC:2.7.7.4]
RALTA_B0631  [KO:K01487] [EC:3.5.4.3]
RALTA_B0810  [KO:K07127] [EC:3.5.2.17]
RALTA_B0811  [KO:K07127] [EC:3.5.2.17]
RALTA_B0814  [KO:K13485] [EC:4.1.1.97]
RALTA_B0848  purAlike; Adenylosuccinate synthase; similar to purA [KO:K01939] [EC:6.3.4.4]
RALTA_B0866  yagT2; xanthine dehydrogenase yagT iron-sulfur binding subunit, putative oxidoreductase, 2Fe-2S subunit [KO:K13483]
RALTA_B0867  yagS2; yagS; molybdopterin dehydrogenase, FAD-binding, CO dehydrogenase flavoprotein, C-terminal [KO:K11178] [EC:1.17.1.4]
RALTA_B0868  yagR2; Xanthine dehydrogenase aldehyde oxidase, molybdenum binding subunit [KO:K11177] [EC:1.17.1.4]
RALTA_B0900  yagR1; Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding [KO:K11177] [EC:1.17.1.4]
RALTA_B0901  yagS1; xanthine dehydrogenase, with FAD-binding domain [KO:K11178] [EC:1.17.1.4]
RALTA_B0902  yagT1; xanthine dehydrogenase, iron-sulfur binding subunit; putative oxidoreductase, 2Fe-2S subunit [KO:K13483]
RALTA_B1000  [KO:K01081] [EC:3.1.3.5]
RALTA_B1275  [KO:K22602] [EC:3.5.1.126]
RALTA_B1825  [KO:K22601] [EC:2.1.3.5]
RALTA_B1920  [KO:K01768] [EC:4.6.1.1]
RALTA_B2202  [KO:K16841] [EC:5.1.99.3]
RALTA_B2203  [KO:K16842] [EC:3.5.2.5]
pRALTA_0265  [KO:K00860] [EC:2.7.1.25]
pRALTA_0354  nodQ-like; nodulation protein, Adenylyl-sulfate kinase (APS kinase) (ATP adenosine-5'-phosphosulfate 3'-phosphotransferase) [KO:K00860] [EC:2.7.1.25]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
cti00030  Pentose phosphate pathway
cti00220  Arginine biosynthesis
cti00250  Alanine, aspartate and glutamate metabolism
cti00260  Glycine, serine and threonine metabolism
cti00340  Histidine metabolism
cti00630  Glyoxylate and dicarboxylate metabolism
cti00730  Thiamine metabolism
cti00740  Riboflavin metabolism
cti00790  Folate biosynthesis
KO pathway
ko00230   

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