KEGG   PATHWAY: cuq00230
Entry
cuq00230                    Pathway                                
Name
Purine metabolism - Corynebacterium ulcerans 210931
Class
Metabolism; Nucleotide metabolism
Pathway map
cuq00230  Purine metabolism
cuq00230

Module
cuq_M00005  PRPP biosynthesis, ribose-5P => PRPP [PATH:cuq00230]
cuq_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:cuq00230]
cuq_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:cuq00230]
cuq_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:cuq00230]
cuq_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:cuq00230]
Other DBs
GO: 0006163 0042278
Organism
Corynebacterium ulcerans 210931 [GN:cuq]
Gene
Cul210931_0094  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
Cul210931_0217  deoD; Purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
Cul210931_0275  cya; Adenylate cyclase [KO:K01768] [EC:4.6.1.1]
Cul210931_0309  gppA1; Ppx/GppA phosphatase family [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Cul210931_0386  nrdD; Anaerobic ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
Cul210931_0438  adk; Adenylate kinase [KO:K00939] [EC:2.7.4.3]
Cul210931_0477  guaB; Inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
Cul210931_0478  guaB2; Inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
Cul210931_0480  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
Cul210931_0519  add; Adenosine deaminase [KO:K01488] [EC:3.5.4.4]
Cul210931_0547  purK; Phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
Cul210931_0548  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
Cul210931_0692  purN; Phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
Cul210931_0693  purH; Bifunctional purine biosynthesis protein [KO:K00602] [EC:2.1.2.3 3.5.4.10]
Cul210931_0749  prs; Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
Cul210931_0763  gppA2; Ppx/GppA phosphatase family [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Cul210931_1144  [KO:K01951] [EC:6.3.5.2]
Cul210931_1191  gmk; Guanylate kinase [KO:K00942] [EC:2.7.4.8]
Cul210931_1230  relA; GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
Cul210931_1231  apt; Adenine phosphoribosyltransferase (APRT) [KO:K00759] [EC:2.4.2.7]
Cul210931_1248  [KO:K19710] [EC:2.7.7.53]
Cul210931_1464  [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
Cul210931_1528  [KO:K26110]
Cul210931_1560  [KO:K02566] [EC:3.1.3.5]
Cul210931_1586  dgt; Deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
Cul210931_1664  ndk; Nucleoside diphosphate kinase (NDK) (NDP kinase) [KO:K00940] [EC:2.7.4.6]
Cul210931_1730  [KO:K01519] [EC:3.6.1.66]
Cul210931_1748  nrdF1; Ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
Cul210931_1750  nrdE; Ribonucleoside-diphosphate reductase [KO:K00525] [EC:1.17.4.1]
Cul210931_1766  pgm; Phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
Cul210931_1806  purM; Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
Cul210931_1807  purF; Amidophosphoribosyltransferase (ATase) [KO:K00764] [EC:2.4.2.14]
Cul210931_1810  nrdF2; Ribonucleoside-diphosphate reductase beta chain 2 [KO:K00526] [EC:1.17.4.1]
Cul210931_1812  purL; Phosphoribosylformylglycinamidine synthase 2 [KO:K23269]
Cul210931_1813  purQ; Phosphoribosylformylglycinamidine synthase 1 [KO:K23265]
Cul210931_1814  purS; Phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264]
Cul210931_1817  purC; Phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
Cul210931_1818  purB; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
Cul210931_1821  purD; Phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
Cul210931_1918  [KO:K25589]
Cul210931_1939  hpt; Hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
Cul210931_1988  purT; Phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
Cul210931_2002  purA; Adenylosuccinate synthetase (AMPSase) (AdSS) [KO:K01939] [EC:6.3.4.4]
Cul210931_2080  ureC; Urease subunit alpha [KO:K01428] [EC:3.5.1.5]
Cul210931_2081  ureB; Urease subunit beta [KO:K01429] [EC:3.5.1.5]
Cul210931_2082  ureA; Urease subunit gamma [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
cuq00030  Pentose phosphate pathway
cuq00220  Arginine biosynthesis
cuq00250  Alanine, aspartate and glutamate metabolism
cuq00260  Glycine, serine and threonine metabolism
cuq00340  Histidine metabolism
cuq00630  Glyoxylate and dicarboxylate metabolism
cuq00730  Thiamine metabolism
cuq00740  Riboflavin metabolism
cuq00790  Folate biosynthesis
KO pathway
ko00230   

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