KEGG   DRUG: ゾルピデム酒石酸塩
エントリ  
D00706                      Drug                                   
一般名   
ゾルピデム酒石酸塩 (JP18);
Zolpidem tartrate (JP18/USP)
商品名   
  後発品
米国の商品 
  後発品
ZOLPIDEM (ACI Healthcare USA), ZOLPIDEM (Aphena Pharma Solutions - Tennessee), ZOLPIDEM (Bryant Ranch Prepack), ZOLPIDEM (Bryant Ranch Prepack), ZOLPIDEM (Bryant Ranch Prepack), ZOLPIDEM (Bryant Ranch Prepack), ZOLPIDEM (Bryant Ranch Prepack), ZOLPIDEM (Bryant Ranch Prepack), ZOLPIDEM (Bryant Ranch Prepack), ZOLPIDEM (Bryant Ranch Prepack), ZOLPIDEM (Bryant Ranch Prepack), ZOLPIDEM (Bryant Ranch Prepack), ZOLPIDEM (Golden State Medical Supply), ZOLPIDEM (NuCare Pharmaceuticals), ZOLPIDEM (NuCare Pharmaceuticals), ZOLPIDEM (NuCare Pharmaceuticals), ZOLPIDEM (Proficient Rx LP), ZOLPIDEM TARTRATE (A-S Medication Solutions), ZOLPIDEM TARTRATE (A-S Medication Solutions), ZOLPIDEM TARTRATE (A-S Medication Solutions), ZOLPIDEM TARTRATE (A-S Medication Solutions), ZOLPIDEM TARTRATE (A-S Medication Solutions), ZOLPIDEM TARTRATE (A-S Medication Solutions), ZOLPIDEM TARTRATE (A-S Medication Solutions), ZOLPIDEM TARTRATE (A-S Medication Solutions), ZOLPIDEM TARTRATE (Advanced Rx Pharmacy of Tennessee), ZOLPIDEM TARTRATE (Advanced Rx Pharmacy of Tennessee), ZOLPIDEM TARTRATE (Advanced Rx Pharmacy of Tennessee), ZOLPIDEM TARTRATE (Advanced Rx Pharmacy of Tennessee), ZOLPIDEM TARTRATE (Advanced Rx Pharmacy of Tennessee), ZOLPIDEM TARTRATE (Advanced Rx Pharmacy of Tennessee), ZOLPIDEM TARTRATE (Advanced Rx Pharmacy of Tennessee), ZOLPIDEM TARTRATE (Advanced Rx Pharmacy of Tennessee), ZOLPIDEM TARTRATE (American Health Packaging), ZOLPIDEM TARTRATE (Aphena Pharma Solutions - Tennessee), ZOLPIDEM TARTRATE (Aphena Pharma Solutions - Tennessee), ZOLPIDEM TARTRATE (Aphena Pharma Solutions - Tennessee), ZOLPIDEM TARTRATE (Aphena Pharma Solutions - Tennessee), ZOLPIDEM TARTRATE (Aphena Pharma Solutions - Tennessee), ZOLPIDEM TARTRATE (Aphena Pharma Solutions - Tennessee), ZOLPIDEM TARTRATE (Aphena Pharma Solutions - Tennessee), ZOLPIDEM TARTRATE (Aphena Pharma Solutions - Tennessee), ZOLPIDEM TARTRATE (Aphena Pharma Solutions - Tennessee), ZOLPIDEM TARTRATE (Aphena Pharma Solutions - Tennessee), ZOLPIDEM TARTRATE (Asclemed USA), ZOLPIDEM TARTRATE (Asclemed USA), ZOLPIDEM TARTRATE (Aurobindo Pharma Limited), ZOLPIDEM TARTRATE (AvKARE), ZOLPIDEM TARTRATE (Breckenridge Pharmaceutical), ZOLPIDEM TARTRATE (Bryant Ranch Prepack), ZOLPIDEM TARTRATE (Bryant Ranch Prepack), ZOLPIDEM TARTRATE (Bryant Ranch Prepack), ZOLPIDEM TARTRATE (Bryant Ranch Prepack), ZOLPIDEM TARTRATE (Bryant Ranch Prepack), ZOLPIDEM TARTRATE (Bryant Ranch Prepack), ZOLPIDEM TARTRATE (Bryant Ranch Prepack), ZOLPIDEM TARTRATE (Calvin Scott &), ZOLPIDEM TARTRATE (Cardinal Health 107), ZOLPIDEM TARTRATE (DIRECT RX), ZOLPIDEM TARTRATE (Denton Pharma), ZOLPIDEM TARTRATE (DirectRX), ZOLPIDEM TARTRATE (Direct_Rx), ZOLPIDEM TARTRATE (Lake Erie Medical DBA Quality Care Products LLC), ZOLPIDEM TARTRATE (Lake Erie Medical DBA Quality Care Products LLC), ZOLPIDEM TARTRATE (Lupin Pharmaceuticals), ZOLPIDEM TARTRATE (Lupin Pharmaceuticals), ZOLPIDEM TARTRATE (Major Pharmaceuticals), ZOLPIDEM TARTRATE (McKesson Corporation dba SKY Packaging), ZOLPIDEM TARTRATE (Medsource Pharmaceuticals), ZOLPIDEM TARTRATE (Medsource Pharmaceuticals), ZOLPIDEM TARTRATE (NorthStar Rx LLC), ZOLPIDEM TARTRATE (NuCare Pharmaceuticals), ZOLPIDEM TARTRATE (NuCare Pharmaceuticals), ZOLPIDEM TARTRATE (NuCare Pharmaceuticals), ZOLPIDEM TARTRATE (NuCare Pharmaceuticals), ZOLPIDEM TARTRATE (NuCare Pharmaceuticals), ZOLPIDEM TARTRATE (NuCare Pharmaceuticals), ZOLPIDEM TARTRATE (NuCare Pharmaceuticals), ZOLPIDEM TARTRATE (PD-Rx Pharmaceuticals), ZOLPIDEM TARTRATE (PD-Rx Pharmaceuticals), ZOLPIDEM TARTRATE (PD-Rx Pharmaceuticals), ZOLPIDEM TARTRATE (PD-Rx Pharmaceuticals), ZOLPIDEM TARTRATE (Par Pharmaceutical), ZOLPIDEM TARTRATE (Preferred Pharmaceuticals), ZOLPIDEM TARTRATE (Preferred Pharmaceuticals), ZOLPIDEM TARTRATE (Preferred Pharmaceuticals), ZOLPIDEM TARTRATE (Preferred Pharmaceuticals), ZOLPIDEM TARTRATE (Preferred Pharmaceuticals), ZOLPIDEM TARTRATE (Preferred Pharmaceuticals), ZOLPIDEM TARTRATE (Proficient Rx LP), ZOLPIDEM TARTRATE (Proficient Rx LP), ZOLPIDEM TARTRATE (Proficient Rx LP), ZOLPIDEM TARTRATE (Proficient Rx LP), ZOLPIDEM TARTRATE (Proficient Rx LP), ZOLPIDEM TARTRATE (Proficient Rx LP), ZOLPIDEM TARTRATE (Proficient Rx LP), ZOLPIDEM TARTRATE (Proficient Rx LP), ZOLPIDEM TARTRATE (Quality Care Products LLC), ZOLPIDEM TARTRATE (Quality Care Products), ZOLPIDEM TARTRATE (Quality Care Products), ZOLPIDEM TARTRATE (REMEDYREPACK), ZOLPIDEM TARTRATE (REMEDYREPACK), ZOLPIDEM TARTRATE (REMEDYREPACK), ZOLPIDEM TARTRATE (REMEDYREPACK), ZOLPIDEM TARTRATE (RPK Pharmaceuticals), ZOLPIDEM TARTRATE (Sandoz), ZOLPIDEM TARTRATE (Sandoz), ZOLPIDEM TARTRATE (St Marys Medical Park Pharmacy), ZOLPIDEM TARTRATE (St. Mary's Medical Park Pharmacy), ZOLPIDEM TARTRATE (Sun Pharmaceutical Industries), ZOLPIDEM TARTRATE (Teva Pharmaceuticals USA), ZOLPIDEM TARTRATE (Torrent Pharmaceuticals Limited), ZOLPIDEM TARTRATE (Winthrop U.S), ZOLPIDEM TARTRATE (medsource pharmaceuticals), ZOLPIDEM TARTRATE SUBLINGUAL (Par Pharmaceutical)
組成式   
(C19H21N3O)2. C4H6O6
質量    
764.3534
分子量   
764.86
構造式   
クラス   
精神神経系用薬
 DG01836  非ベンゾジアゼピン系催眠鎮静薬
 DG03202  睡眠薬
 DG01567  GABA-A受容体作動薬
代謝酵素基質薬
 DG01892  CYP1A2基質薬
 DG01642  CYP2C9基質薬
 DG01633  CYP3A/CYP3A4基質薬
  DG02913  CYP3A4基質薬
コード   
薬効分類: 1129
ATCコード: N05CF02
化学構造グループ: DG00922
商品 (DG00922): D00706<JP/US>
効能    
催眠鎮静薬
  疾患
不眠症 [DS:H01609]
コメント  
超短時間型非ベンゾジアゼピン系 (イミダゾピリジン誘導体)
ターゲット 
  パスウェイ
hsa04080  神経刺激性リガンドとレセプターの相互作用
hsa04727  GABA作動性シナプス
代謝    
Enzyme: CYP3A4 [HSA:1576]; CYP2C9 [HSA:1559], CYP1A2 [HSA:1544]
相互作用  

構造マップ 
map07032  催眠薬
map07230  GABA-A受容体の作動薬と拮抗薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 1  神経系及び感覚器官用医薬品
  11  中枢神経系用薬
   112  催眠鎮静剤、抗不安剤
    1129  その他の催眠鎮静剤、抗不安剤
     D00706  ゾルピデム酒石酸塩 (JP18)
医療用医薬品のATC分類 [BR:jp08303]
 N 神経系
  N05 精神抑制薬
   N05C 睡眠薬と鎮静薬
    N05CF ベンゾジアゼピン関連薬物
     N05CF02 ゾルピデム
      D00706  ゾルピデム酒石酸塩 (JP18) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 睡眠障害治療薬
  睡眠促進薬
   ゾルピデム
    D00706  ゾルピデム酒石酸塩 (JP18)
医薬品グループ [BR:jp08330]
 精神神経系用薬
  DG01836  非ベンゾジアゼピン系催眠鎮静薬
   DG00922  ゾルピデム
    D00706  ゾルピデム酒石酸塩
  DG03202  睡眠薬
   DG00922  ゾルピデム
    D00706  ゾルピデム酒石酸塩
  DG01567  GABA-A受容体作動薬
   DG00922  ゾルピデム
    D00706  ゾルピデム酒石酸塩
 代謝酵素基質薬
  DG01892  CYP1A2基質薬
   DG00922  ゾルピデム
    D00706  ゾルピデム酒石酸塩
  DG01642  CYP2C9基質薬
   DG00922  ゾルピデム
    D00706  ゾルピデム酒石酸塩
  DG01633  CYP3A/CYP3A4基質薬
   DG02913  CYP3A4基質薬
    DG00922  ゾルピデム
     D00706  ゾルピデム酒石酸塩
医薬品クラス [BR:jp08332]
 精神神経系用薬
  DG03202  睡眠薬 [商品一覧]
   D00706  ゾルピデム酒石酸塩
ターゲットに基づく医薬品分類 [BR:jp08310]
 イオンチャネル
  リガンド依存性イオンチャネル
   GABA (イオンチャネル型)
    GABR
     D00706  ゾルピデム酒石酸塩 (JP18) <JP/US>
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D00706  ゾルピデム酒石酸塩
  D00706  ゾルピデム酒石酸塩錠
日本の新薬 [jp08318.html]
 新有効成分含有医薬品
  D00706
薬物代謝酵素とトランスポーター [jp08309.html]
 薬物代謝酵素
  D00706
医薬品グループ [BR:jp08330]
 精神神経系用薬
  DG01836  非ベンゾジアゼピン系催眠鎮静薬
   DG00922  ゾルピデム
  DG03202  睡眠薬
   DG00922  ゾルピデム
  DG01567  GABA-A受容体作動薬
   DG00922  ゾルピデム
 代謝酵素基質薬
  DG01892  CYP1A2基質薬
   DG00922  ゾルピデム
  DG01642  CYP2C9基質薬
   DG00922  ゾルピデム
  DG01633  CYP3A/CYP3A4基質薬
   DG02913  CYP3A4基質薬
    DG00922  ゾルピデム
リンク   
CAS: 99294-93-6
PubChem: 7847771
LigandBox: D00706
日化辞: J375.045K
LinkDB    

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