KEGG   PATHWAY: ear00330
Entry
ear00330                    Pathway                                
Name
Arginine and proline metabolism - Klebsiella aerogenes EA1509E
Class
Metabolism; Amino acid metabolism
Pathway map
ear00330  Arginine and proline metabolism
ear00330

Module
ear_M00015  Proline biosynthesis, glutamate => proline [PATH:ear00330]
ear_M00133  Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:ear00330]
ear_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:ear00330]
ear_M00136  GABA biosynthesis, prokaryotes, putrescine => GABA [PATH:ear00330]
ear_M00879  Arginine succinyltransferase pathway, arginine => glutamate [PATH:ear00330]
ear_M00970  Proline degradation, proline => glutamate [PATH:ear00330]
Other DBs
GO: 0006525 0006560
Organism
Klebsiella aerogenes EA1509E [GN:ear]
Gene
CCG32973  Cytosine deaminase (EC 3.5.4.1) [KO:K01485] [EC:3.5.4.1 3.5.4.21]
CCG33366  Biosynthetic arginine decarboxylase (EC 4.1.1.19) [KO:K01585] [EC:4.1.1.19]
CCG33368  Agmatinase (EC 3.5.3.11) [KO:K01480] [EC:3.5.3.11]
CCG33338  Ornithine decarboxylase (EC 4.1.1.17) [KO:K01581] [EC:4.1.1.17]
CCG33488  Ornithine decarboxylase (EC 4.1.1.17) [KO:K01581] [EC:4.1.1.17]
CCG31698  Spermidine synthase (EC 2.5.1.16) [KO:K00797] [EC:2.5.1.16]
CCG31699  S-adenosylmethionine decarboxylase proenzyme (EC 4.1.1.50), prokaryotic class 1A [KO:K01611] [EC:4.1.1.50]
CCG33216  Putrescine aminotransferase (EC 2.6.1.82) [KO:K09251] [EC:2.6.1.82]
CCG33301  Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) [KO:K12256] [EC:2.6.1.113]
CCG29854  4-aminobutyraldehyde dehydrogenase (EC 1.2.1.19) [KO:K00137] [EC:1.2.1.19]
CCG30211  Spermidine N1-acetyltransferase (EC 2.3.1.57) [KO:K00657] [EC:2.3.1.57]
CCG31957  Acetamidase (EC 3.5.1.4) [KO:K01426] [EC:3.5.1.4]
CCG33525  Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [KO:K01426] [EC:3.5.1.4]
CCG29618  Arginine N-succinyltransferase (EC 2.3.1.109) [KO:K00673] [EC:2.3.1.109]
CCG29800  Arginine N-succinyltransferase (EC 2.3.1.109) [KO:K00673] [EC:2.3.1.109]
CCG29802  Succinylarginine dihydrolase (EC 3.5.3.23) [KO:K01484] [EC:3.5.3.23]
CCG29617  Succinylornithine transaminase (EC 2.6.1.81) [KO:K00840] [EC:2.6.1.81]
CCG29799  Succinylornithine transaminase (EC 2.6.1.81) [KO:K00840] [EC:2.6.1.81]
CCG29619  Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) [KO:K06447] [EC:1.2.1.71]
CCG29801  Succinylglutamic semialdehyde dehydrogenase (EC 1.2.1.71) [KO:K06447] [EC:1.2.1.71]
CCG29620  Succinylglutamate desuccinylase (EC 3.5.1.96) [KO:K05526] [EC:3.5.1.96]
CCG29803  Succinylglutamate desuccinylase (EC 3.5.1.96) [KO:K05526] [EC:3.5.1.96]
CCG30720  Gamma-glutamyl-putrescine synthetase (EC 6.3.1.11) [KO:K09470] [EC:6.3.1.11]
CCG30724  Gamma-glutamyl-putrescine oxidase (EC1.4.3.-) [KO:K09471] [EC:1.4.3.-]
CCG31294  Putative oxidoreductase [KO:K09471] [EC:1.4.3.-]
CCG30723  Gamma-glutamyl-aminobutyraldehyde dehydrogenase (EC 1.2.1.-) [KO:K09472] [EC:1.2.1.99]
CCG33302  Aldehyde dehydrogenase (EC 1.2.1.3) [KO:K09472] [EC:1.2.1.99]
CCG30721  Gamma-glutamyl-GABA hydrolase (EC 3.5.1.94) [KO:K09473] [EC:3.5.1.94]
CCG29960  Arginase (EC 3.5.3.1) [KO:K01476] [EC:3.5.3.1]
CCG31501  Pyrroline-5-carboxylate reductase (EC 1.5.1.2) [KO:K00286] [EC:1.5.1.2]
CCG30697  Transcriptional repressor of PutA and PutP / Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase) / Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) [KO:K13821] [EC:1.5.5.2 1.2.1.88]
CCG31558  Glutamate 5-kinase (EC 2.7.2.11) [KO:K00931] [EC:2.7.2.11]
CCG31557  Gamma-glutamyl phosphate reductase (EC 1.2.1.41) [KO:K00147] [EC:1.2.1.41]
CCG30913  Aspartate aminotransferase (EC 2.6.1.1) [KO:K00813] [EC:2.6.1.1]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
ear00020  Citrate cycle (TCA cycle)
ear00220  Arginine biosynthesis
ear00250  Alanine, aspartate and glutamate metabolism
ear00260  Glycine, serine and threonine metabolism
ear00270  Cysteine and methionine metabolism
ear00310  Lysine degradation
ear00410  beta-Alanine metabolism
ear00470  D-Amino acid metabolism
ear00480  Glutathione metabolism
ear00630  Glyoxylate and dicarboxylate metabolism
ear00650  Butanoate metabolism
ear00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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