KEGG   PATHWAY: ecc00620
Entry
ecc00620                    Pathway                                
Name
Pyruvate metabolism - Escherichia coli O6:K2:H1 CFT073 (UPEC)
Class
Metabolism; Carbohydrate metabolism
Pathway map
ecc00620  Pyruvate metabolism
ecc00620

Module
ecc_M00168  CAM (Crassulacean acid metabolism), dark [PATH:ecc00620]
ecc_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:ecc00620]
ecc_M00579  Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:ecc00620]
Other DBs
GO: 0006090
Organism
Escherichia coli O6:K2:H1 CFT073 (UPEC) [GN:ecc]
Gene
c0091  leuA; 2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
c0142  aceE; Pyruvate dehydrogenase E1 component [KO:K00163] [EC:1.2.4.1]
c0145  lpdA; Dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
c0223  accA; Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [KO:K01962] [EC:6.4.1.2 2.1.3.15]
c0249  gloB; Probable hydroxyacylglutathione hydrolase [KO:K01069] [EC:3.1.2.6]
c0447  yahK; Hypothetical zinc-type alcohol dehydrogenase-like protein yahK [KO:K13979] [EC:1.1.1.2]
c0465  adhC; Alcohol dehydrogenase class III [KO:K00121] [EC:1.1.1.284 1.1.1.1]
c1004  poxB; Pyruvate dehydrogenase (cytochrome) [KO:K00156] [EC:1.2.5.1]
c1069  ycbL; Hypothetical protein ycbL [KO:K01069] [EC:3.1.2.6]
c1106  [KO:K01512] [EC:3.6.1.7]
c1295  ycdW; Putative 2-hydroxyacid dehydrogenase ycdW [KO:K12972] [EC:1.1.1.79 1.1.1.81]
c1705  adhE; Aldehyde-alcohol dehydrogenase [KO:K04072] [EC:1.2.1.10 1.1.1.1]
c1823  ydbK; Probable pyruvate-flavodoxin oxidoreductase [KO:K03737] [EC:1.2.7.1 1.2.8.1]
c1827  ldhA; D-lactate dehydrogenase [KO:K03778] [EC:1.1.1.28]
c1842  aldA; Aldehyde dehydrogenase A [KO:K07248] [EC:1.2.1.22 1.2.1.21]
c1911  adhP; Alcohol dehydrogenase, propanol-preferring [KO:K13953] [EC:1.1.1.1]
c1912  sfcA; NAD-dependent malic enzyme [KO:K00027] [EC:1.1.1.38]
c2003  fumC; Fumarate hydratase class II [KO:K01679] [EC:4.2.1.2]
c2004  fumA; Fumarate hydratase class I, aerobic [KO:K01676] [EC:4.2.1.2]
c2044  gloA; Lactoylglutathione lyase [KO:K01759] [EC:4.4.1.5]
c2069  ydhZ; Hypothetical protein ydhZ [KO:K01675]
c2071  pykF; Pyruvate kinase I [KO:K00873] [EC:2.7.1.40]
c2098  ppsA; Phosphoenolpyruvate synthase [KO:K01007] [EC:2.7.9.2]
c2268  pykA; Pyruvate kinase II [KO:K00873] [EC:2.7.1.40]
c2385  yedU; Protein yedU [KO:K05523] [EC:4.2.1.130 3.5.1.124]
c2664  dld; D-lactate dehydrogenase [KO:K03777] [EC:1.1.5.12]
c2751  yojH; Malate:quinone oxidoreductase [KO:K00116] [EC:1.1.5.4]
c2767  atoB; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
c2838  ackA; Acetate kinase [KO:K00925] [EC:2.7.2.1]
c2840  pta; Phosphate acetyltransferase [KO:K13788] [EC:2.3.1.8]
c2861  accD; Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta [KO:K01963] [EC:6.4.1.2 2.1.3.15]
c2978  eutG; Ethanolamine utilization protein eutG [KO:K04022]
c2980  eutE; Ethanolamine utilization protein eutE [KO:K04021]
c2983  eutI; Ethanolamine utilization protein eutD [KO:K04020]
c2988  [KO:K00029] [EC:1.1.1.40]
c3441  yqeF; Probable acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
c3512  yggD; Hypothetical protein yggD [KO:K01774]
c3705  glcB; Malate synthase G [KO:K01638] [EC:2.3.3.9]
c3872  tdcE; Keto-acid formate acetyltransferase [KO:K00656] [EC:2.3.1.54]
c3991  mdh; Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
c4011  accB; Biotin carboxyl carrier protein of acetyl-CoA carboxylase [KO:K02160]
c4012  accC; Biotin carboxylase [KO:K01961] [EC:6.4.1.2 6.3.4.14]
c4176  pckA; Phosphoenolpyruvate carboxykinase (ATP) [KO:K01610] [EC:4.1.1.49]
c4372  yiaE; 2-ketogluconate reductase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
c4408  aldB; Aldehyde dehydrogenase B [KO:K00138] [EC:1.2.1.-]
c4410  yiaY; Probable alcohol dehydrogenase [KO:K13954] [EC:1.1.1.1]
c4427  lldD; L-lactate dehydrogenase [KO:K00101] [EC:1.1.2.3]
c4915  ppc; Phosphoenolpyruvate carboxylase [KO:K01595] [EC:4.1.1.31]
c4971  aceB; Malate synthase A [KO:K01638] [EC:2.3.3.9]
c5024  [KO:K01026] [EC:2.8.3.1]
c5035  [KO:K00382] [EC:1.8.1.4]
c5039  [KO:K00016] [EC:1.1.1.27]
c5064  acs; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
c5127  fumB; Fumarate hydratase class I, anaerobic [KO:K01676] [EC:4.2.1.2]
c5239  frdD; Fumarate reductase 13 kDa hydrophobic protein [KO:K00247]
c5240  frdC; Fumarate reductase 15 kDa hydrophobic protein [KO:K00246]
c5241  frdB; Fumarate reductase iron-sulfur protein [KO:K00245] [EC:1.3.5.1]
c5242  frdA; Fumarate reductase flavoprotein subunit [KO:K00244] [EC:1.3.5.1]
c5300  [KO:K01026] [EC:2.8.3.1]
c5370  yjgB; Hypothetical zinc-type alcohol dehydrogenase-like protein yjgB [KO:K12957] [EC:1.1.1.2 1.1.1.183]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00033  Acetate
C00036  Oxaloacetate
C00042  Succinate
C00058  Formate
C00068  Thiamin diphosphate
C00074  Phosphoenolpyruvate
C00083  Malonyl-CoA
C00084  Acetaldehyde
C00122  Fumarate
C00149  (S)-Malate
C00186  (S)-Lactate
C00227  Acetyl phosphate
C00256  (R)-Lactate
C00332  Acetoacetyl-CoA
C00424  (S)-Lactaldehyde
C00469  Ethanol
C00546  Methylglyoxal
C00937  (R)-Lactaldehyde
C01251  (R)-2-Hydroxybutane-1,2,4-tricarboxylate
C02488  (R)-2-Ethylmalate
C02504  alpha-Isopropylmalate
C03248  Acetylenedicarboxylate
C03451  (R)-S-Lactoylglutathione
C03981  2-Hydroxyethylenedicarboxylate
C05125  2-(alpha-Hydroxyethyl)thiamine diphosphate
C05993  Acetyl adenylate
C05994  2-Propylmalate
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16255  [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Related
pathway
ecc00010  Glycolysis / Gluconeogenesis
ecc00020  Citrate cycle (TCA cycle)
ecc00061  Fatty acid biosynthesis
ecc00250  Alanine, aspartate and glutamate metabolism
ecc00260  Glycine, serine and threonine metabolism
ecc00290  Valine, leucine and isoleucine biosynthesis
ecc00300  Lysine biosynthesis
ecc00630  Glyoxylate and dicarboxylate metabolism
ecc00640  Propanoate metabolism
ecc00650  Butanoate metabolism
ecc00760  Nicotinate and nicotinamide metabolism
KO pathway
ko00620   

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