KEGG   PATHWAY: ftc00230
Entry
ftc00230                    Pathway                                
Name
Purine metabolism - Francisella tularensis subsp. holarctica FTT_1
Class
Metabolism; Nucleotide metabolism
Pathway map
ftc00230  Purine metabolism
ftc00230

Module
ftc_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:ftc00230]
ftc_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:ftc00230]
ftc_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ftc00230]
ftc_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:ftc00230]
ftc_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:ftc00230]
Other DBs
GO: 0006163 0042278
Organism
Francisella tularensis subsp. holarctica FTT_1 [GN:ftc]
Gene
DA46_1078  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
DA46_211  phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III family protein [KO:K01835] [EC:5.4.2.2]
DA46_1857  prs; ribose-phosphate diphosphokinase family protein [KO:K00948] [EC:2.7.6.1]
DA46_863  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
DA46_310  purD; phosphoribosylamine--glycine ligase [KO:K13713] [EC:6.3.2.6 6.3.4.13]
DA46_309  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
DA46_644  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
DA46_864  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
DA46_311  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
DA46_306  purK; phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
DA46_308  purE; phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
DA46_874  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
DA46_790  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
DA46_943  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
DA46_1289  deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
DA46_1931  multi-copper polyphenol oxidoreductase laccase family protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
DA46_788  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
DA46_1274  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
DA46_1460  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
DA46_137  rdgB; non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
DA46_1727  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
DA46_1367  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
DA46_1817  ribonucleoside-diphosphate reductase, alpha subunit [KO:K00525] [EC:1.17.4.1]
DA46_1820  ribonucleotide reductase, small chain family protein [KO:K00526 K03676] [EC:1.17.4.1]
DA46_1249  dgt; dGTPase family protein [KO:K01129] [EC:3.1.5.1]
DA46_1342  RelA/SpoT family protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
DA46_69  ppx/GppA phosphatase family protein [KO:K01524] [EC:3.6.1.11 3.6.1.40]
DA46_426  RelA/SpoT family protein [KO:K00951] [EC:2.7.6.5]
DA46_789  purA; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
DA46_1372  adenosine/AMP deaminase family protein [KO:K01488] [EC:3.5.4.4]
DA46_1503  add; adenosine deaminase [KO:K21053] [EC:3.5.4.2]
DA46_2017  adenylate kinase family protein [KO:K00939] [EC:2.7.4.3]
DA46_1153  apaH; Diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
DA46_1761  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
DA46_1763  cysN; sulfate adenylyltransferase, large subunit [KO:K00956] [EC:2.7.7.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
ftc00030  Pentose phosphate pathway
ftc00220  Arginine biosynthesis
ftc00250  Alanine, aspartate and glutamate metabolism
ftc00260  Glycine, serine and threonine metabolism
ftc00630  Glyoxylate and dicarboxylate metabolism
ftc00730  Thiamine metabolism
ftc00740  Riboflavin metabolism
ftc00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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