KEGG   PATHWAY: ftu00230
Entry
ftu00230                    Pathway                                
Name
Purine metabolism - Francisella tularensis subsp. tularensis SCHU S4
Class
Metabolism; Nucleotide metabolism
Pathway map
ftu00230  Purine metabolism
ftu00230

Module
ftu_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:ftu00230]
ftu_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:ftu00230]
ftu_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ftu00230]
ftu_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:ftu00230]
ftu_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:ftu00230]
Other DBs
GO: 0006163 0042278
Organism
Francisella tularensis subsp. tularensis SCHU S4 [GN:ftu]
Gene
FTT_0113  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
FTT_0414  pgm; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
FTT_0674  prsA; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
FTT_1721c  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
FTT_0894  purCD; fusion protein PurC/PurD [KO:K13713] [EC:6.3.2.6 6.3.4.13]
FTT_0895  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
FTT_1767c  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
FTT_1720c  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
FTT_0893  purM; phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
FTT_0897  purK; 5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
FTT_0896  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
FTT_0015  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
FTT_0203c  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
FTT_0078  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
FTT_0766  deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
FTT_0608  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
FTT_0205  hpt; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
FTT_1317c  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
FTT_0373c  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
FTT_1560  deoxyribonucleotide triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
FTT_1019c  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
FTT_0909  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
FTT_1470c  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
FTT_0534c  nrdA; ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
FTT_0532c  grxC; bifunctional gluaredoxin/ribonucleoside-diphosphate reductase subunit beta [KO:K00526 K03676] [EC:1.17.4.1]
FTT_0720c  dgt; deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
FTT_0808  spoT; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
FTT_1444c  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
FTT_1508c  relA; GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
FTT_0204  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
FTT_0939c  add1; adenosine deaminase [KO:K21053] [EC:3.5.4.2]
FTT_1161  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
FTT_0470  apaH; diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
FTT_1050c  cysN; sulfate adenylyltransferase [KO:K00956] [EC:2.7.7.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
ftu00030  Pentose phosphate pathway
ftu00220  Arginine biosynthesis
ftu00250  Alanine, aspartate and glutamate metabolism
ftu00260  Glycine, serine and threonine metabolism
ftu00630  Glyoxylate and dicarboxylate metabolism
ftu00730  Thiamine metabolism
ftu00740  Riboflavin metabolism
ftu00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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