KEGG   PATHWAY: ftz00230
Entry
ftz00230                    Pathway                                
Name
Purine metabolism - Francisella tularensis subsp. holarctica 425
Class
Metabolism; Nucleotide metabolism
Pathway map
ftz00230  Purine metabolism
ftz00230

Module
ftz_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:ftz00230]
ftz_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:ftz00230]
ftz_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ftz00230]
ftz_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:ftz00230]
ftz_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:ftz00230]
Other DBs
GO: 0006163 0042278
Organism
Francisella tularensis subsp. holarctica 425 [GN:ftz]
Gene
CH68_1018  prs; ribose-phosphate diphosphokinase family protein [KO:K00948] [EC:2.7.6.1]
CH68_1055  [KO:K00526 K03676] [EC:1.17.4.1]
CH68_1058  [KO:K00525] [EC:1.17.4.1]
CH68_1112  cysN; sulfate adenylyltransferase, large subunit [KO:K00956] [EC:2.7.7.4]
CH68_1114  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
CH68_1148  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
CH68_1375  add; adenosine deaminase [KO:K21053] [EC:3.5.4.2]
CH68_1418  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
CH68_1506  [KO:K01488] [EC:3.5.4.4]
CH68_1511  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
CH68_1536  [KO:K01139] [EC:2.7.6.5 3.1.7.2]
CH68_1588  deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
CH68_1603  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
CH68_1628  dgt; dGTPase family protein [KO:K01129] [EC:3.1.5.1]
CH68_1726  apaH; Diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
CH68_1800  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
CH68_1935  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
CH68_2005  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
CH68_2015  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
CH68_2016  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
CH68_2086  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
CH68_2087  purA; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
CH68_2088  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
CH68_301  [KO:K00951] [EC:2.7.6.5]
CH68_419  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
CH68_420  purD; phosphoribosylamine--glycine ligase [KO:K13713] [EC:6.3.2.6 6.3.4.13]
CH68_421  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
CH68_422  purE; phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
CH68_424  purK; phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
CH68_519  [KO:K01835] [EC:5.4.2.2]
CH68_592  rdgB; non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
CH68_661  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CH68_858  [KO:K00939] [EC:2.7.4.3]
CH68_86  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
CH68_945  [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
ftz00030  Pentose phosphate pathway
ftz00220  Arginine biosynthesis
ftz00250  Alanine, aspartate and glutamate metabolism
ftz00260  Glycine, serine and threonine metabolism
ftz00630  Glyoxylate and dicarboxylate metabolism
ftz00730  Thiamine metabolism
ftz00740  Riboflavin metabolism
ftz00790  Folate biosynthesis
KO pathway
ko00230   

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