KEGG   PATHWAY: hgl00630
Entry
hgl00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Heterocephalus glaber (naked mole-rat)
Class
Metabolism; Carbohydrate metabolism
Pathway map
hgl00630  Glyoxylate and dicarboxylate metabolism
hgl00630

Module
hgl_M00621  Glycine cleavage system [PATH:hgl00630]
hgl_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:hgl00630]
Other DBs
GO: 0046487 0043648
Organism
Heterocephalus glaber (naked mole-rat) [GN:hgl]
Gene
101718141  Acss1; acyl-CoA synthetase short-chain family member 1 [KO:K01895] [EC:6.2.1.1]
101703127  Acss2; acyl-CoA synthetase short-chain family member 2 [KO:K01895] [EC:6.2.1.1]
101719728  Mdh1; malate dehydrogenase 1 [KO:K00025] [EC:1.1.1.37]
101713764  Mdh2; malate dehydrogenase 2 [KO:K00026] [EC:1.1.1.37]
101710152  Cs; citrate synthase [KO:K01647] [EC:2.3.3.1]
101716545  Aco1; aconitase 1 [KO:K01681] [EC:4.2.1.3]
101705755  Aco2; aconitase 2 [KO:K01681] [EC:4.2.1.3]
101709659  Acat1; acetyl-CoA acetyltransferase 1 [KO:K00626] [EC:2.3.1.9]
101712256  Acat2; acetyl-CoA acetyltransferase 2 [KO:K00626] [EC:2.3.1.9]
101724683  Mcee; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
101711474  Pcca; propionyl-CoA carboxylase alpha subunit [KO:K01965] [EC:6.4.1.3]
101699369  Pccb; propionyl-CoA carboxylase beta subunit [KO:K01966] [EC:6.4.1.3 2.1.3.15]
101726092  Mut; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
101724381  Hao1; hydroxyacid oxidase 1 [KO:K11517] [EC:1.1.3.15]
101705559  Hao2; hydroxyacid oxidase 2 [KO:K11517] [EC:1.1.3.15]
101707368  Cat; catalase [KO:K03781] [EC:1.11.1.6]
101701531  Grhpr; glyoxylate and hydroxypyruvate reductase [KO:K00049] [EC:1.1.1.79 1.1.1.81]
101711561  Pgp; phosphoglycolate phosphatase [KO:K19269] [EC:3.1.3.18 3.1.3.48]
101709143  Agxt; alanine-glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
101696542  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
101703275  Glul; glutamate-ammonia ligase [KO:K01915] [EC:6.3.1.2]
101721429  Shmt2; serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
101726020  Shmt1; serine hydroxymethyltransferase 1 [KO:K00600] [EC:2.1.2.1]
101725465  Gldc; glycine decarboxylase [KO:K00281] [EC:1.4.4.2]
101711434  Amt; aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
101699518  Dld; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
101724619  Gcsh; glycine cleavage system protein H [KO:K02437]
101720613  glycine cleavage system H protein, mitochondrial [KO:K02437]
106009802  glycine cleavage system H protein, mitochondrial-like [KO:K02437]
101707719  glycine cleavage system H protein, mitochondrial-like [KO:K02437]
101715931  glycine cleavage system H protein, mitochondrial-like [KO:K02437]
101711073  glycine cleavage system H protein, mitochondrial-like [KO:K02437]
101709630  Hyi; hydroxypyruvate isomerase (putative) [KO:K01816] [EC:5.3.1.22]
101705421  Glyctk; glycerate kinase [KO:K11529] [EC:2.7.1.165]
101700602  Hoga1; 4-hydroxy-2-oxoglutarate aldolase 1 [KO:K18123] [EC:4.1.3.16]
101701788  Afmid; arylformamidase [KO:K01432] [EC:3.5.1.9]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
hgl00010  Glycolysis / Gluconeogenesis
hgl00020  Citrate cycle (TCA cycle)
hgl00030  Pentose phosphate pathway
hgl00053  Ascorbate and aldarate metabolism
hgl00071  Fatty acid degradation
hgl00230  Purine metabolism
hgl00250  Alanine, aspartate and glutamate metabolism
hgl00260  Glycine, serine and threonine metabolism
hgl00620  Pyruvate metabolism
hgl00750  Vitamin B6 metabolism
hgl00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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