KEGG   PATHWAY: hie00230
Entry
hie00230                    Pathway                                
Name
Purine metabolism - Haemophilus influenzae R2846 (nontypeable)
Class
Metabolism; Nucleotide metabolism
Pathway map
hie00230  Purine metabolism
hie00230

Module
hie_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:hie00230]
hie_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:hie00230]
hie_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:hie00230]
hie_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:hie00230]
hie_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:hie00230]
Other DBs
GO: 0006163 0042278
Organism
Haemophilus influenzae R2846 (nontypeable) [GN:hie]
Gene
R2846_0180  nudF; ADP-Ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
R2846_1085  prsA; Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
R2846_1137  purF; Amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
R2846_1429  purD; Phosphoribosylamine-glycine ligase [KO:K01945] [EC:6.3.4.13]
R2846_0905  purN; Phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
R2846_1573  purL; Phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
R2846_0906  purM; Phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
R2846_1092  purK; Phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
R2846_1091  purE; Phosphoribosylaminoimidazole carboxylase, catalytic subunit putative [KO:K01588] [EC:5.4.99.18]
R2846_0668  purC; Phosphoribosylaminoimidazole-succinocarboxamidesynthase [KO:K01923] [EC:6.3.2.6]
R2846_1701  purB; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
R2846_1430  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
R2846_0757  apt; Adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
R2846_0432  nucA; 5-nucleotidase NucA [KO:K11751] [EC:3.1.3.5 3.6.1.45]
R2846_1628  surE; Stationary-phase survival protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
R2846_0067  deoD; Purine-nucleoside phosphorylase (PNPase) [KO:K03784] [EC:2.4.2.1]
R2846_0464  yfiH; Conserved hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
R2846_1189  hpt; Hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
R2846_0379  guaB; Inosine-5-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
R2846_1441  ndk; Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
R2846_0326  rdgB; dITP/XTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
R2846_1645  gptB; Xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
R2846_1660  gptA; Xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
R2846_0378  guaA; GMP synthetase (glutamine-hydrolyzing) [KO:K01951] [EC:6.3.5.2]
R2846_0647  gmk; Guanylate kinase [KO:K00942] [EC:2.7.4.8]
R2846_0734  nrdA; Ribonucleoside-diphosphate reductase 1, alpha subunit [KO:K00525] [EC:1.17.4.1]
R2846_0733  nrdB; Ribonucleoside diphosphate reductase 1, beta subunit [KO:K00526] [EC:1.17.4.1]
R2846_0571  nrdD; Anaerobic ribonucleoside-triphosphate reductase, alpha subunit [KO:K21636] [EC:1.1.98.6]
R2846_0819  dgt; Conserved hypothetical protein [KO:K01129] [EC:3.1.5.1]
R2846_0649  spoT; (p)ppGpp synthetase II/guanosine-3,5-bis pyrophosphate 3-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
R2846_1634  Hypothetical protein [KO:K01524] [EC:3.6.1.11 3.6.1.40]
R2846_0243  relA; GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
R2846_0390  cya; Adenylate cyclase [KO:K05851] [EC:4.6.1.1]
R2846_1111  purA; Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
R2846_1744  cpdB; 23-cyclic-nucleotide 2-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
R2846_0228  adk; Adenylate kinase [KO:K00939] [EC:2.7.4.3]
R2846_0119  mazG; NTP pyrophosphatase MazG [KO:K04765] [EC:3.6.1.9]
R2846_0179  cpdA; cyclic 3,5-adenosine monophosphate phosphodiesterase [KO:K03651] [EC:3.1.4.53]
R2846_0032  apaH; Diadenosine tetraphosphatase (Ap4A hydrolase) [KO:K01525] [EC:3.6.1.41]
R2846_0046  ureC; Urease alpha subunit [KO:K01428] [EC:3.5.1.5]
R2846_0045  ureB; Urease beta subunit [KO:K01429] [EC:3.5.1.5]
R2846_0044  ureA; Urease gamma subunit [KO:K01430] [EC:3.5.1.5]
R2846_1738  arcC; Carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
hie00030  Pentose phosphate pathway
hie00220  Arginine biosynthesis
hie00250  Alanine, aspartate and glutamate metabolism
hie00260  Glycine, serine and threonine metabolism
hie00340  Histidine metabolism
hie00630  Glyoxylate and dicarboxylate metabolism
hie00730  Thiamine metabolism
hie00740  Riboflavin metabolism
hie00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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