KEGG   PATHWAY: hsa00770
Entry
hsa00770                    Pathway                                
Name
Pantothenate and CoA biosynthesis - Homo sapiens (human)
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
hsa00770  Pantothenate and CoA biosynthesis
hsa00770

Module
hsa_M00046  Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:hsa00770]
hsa_M00120  Coenzyme A biosynthesis, pantothenate => CoA [PATH:hsa00770]
Other DBs
GO: 0015940 0015937
Organism
Homo sapiens (human) [GN:hsa]
Gene
1806  DPYD; dihydropyrimidine dehydrogenase [KO:K00207] [EC:1.3.1.2]
1807  DPYS; dihydropyrimidinase [KO:K01464] [EC:3.5.2.2]
217  ALDH2; aldehyde dehydrogenase 2 family member [KO:K00128] [EC:1.2.1.3]
219  ALDH1B1; aldehyde dehydrogenase 1 family member B1 [KO:K00128] [EC:1.2.1.3]
224  ALDH3A2; aldehyde dehydrogenase 3 family member A2 [KO:K00128] [EC:1.2.1.3]
339896  GADL1; glutamate decarboxylase like 1 [KO:K18966] [EC:4.1.1.29 4.1.1.11]
51380  CSAD; cysteine sulfinic acid decarboxylase [KO:K18966] [EC:4.1.1.29 4.1.1.11]
5167  ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase 1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
5169  ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase 3 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
51733  UPB1; beta-ureidopropionase 1 [KO:K01431] [EC:3.5.1.6]
53354  PANK1; pantothenate kinase 1 [KO:K09680] [EC:2.7.1.33]
586  BCAT1; branched chain amino acid transaminase 1 [KO:K00826] [EC:2.6.1.42]
587  BCAT2; branched chain amino acid transaminase 2 [KO:K00826] [EC:2.6.1.42]
60490  PPCDC; phosphopantothenoylcysteine decarboxylase [KO:K01598] [EC:4.1.1.36]
60496  AASDHPPT; aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase [KO:K06133] [EC:2.7.8.-]
79646  PANK3; pantothenate kinase 3 [KO:K09680] [EC:2.7.1.33]
79717  PPCS; phosphopantothenoylcysteine synthetase [KO:K01922] [EC:6.3.2.51]
80025  PANK2; pantothenate kinase 2 [KO:K09680] [EC:2.7.1.33]
80347  COASY; Coenzyme A synthase [KO:K02318] [EC:2.7.7.3 2.7.1.24]
8875  VNN2; vanin 2 [KO:K08069] [EC:3.5.1.92]
8876  VNN1; vanin 1 [KO:K08069] [EC:3.5.1.92]
Compound
C00010  CoA
C00022  Pyruvate
C00049  L-Aspartate
C00054  Adenosine 3',5'-bisphosphate
C00097  L-Cysteine
C00099  beta-Alanine
C00106  Uracil
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00229  Acyl-carrier protein
C00429  5,6-Dihydrouracil
C00522  (R)-Pantoate
C00750  Spermine
C00831  Pantetheine
C00864  Pantothenate
C00882  Dephospho-CoA
C00966  2-Dehydropantoate
C01053  (R)-4-Dehydropantoate
C01088  (R)-3,3-Dimethylmalate
C01134  Pantetheine 4'-phosphate
C02642  3-Ureidopropionate
C03492  D-4'-Phosphopantothenate
C03688  Apo-[acyl-carrier-protein]
C04079  N-((R)-Pantothenoyl)-L-cysteine
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04352  (R)-4'-Phosphopantothenoyl-L-cysteine
C05665  3-Aminopropanal
C05944  Pantothenol
C06010  (S)-2-Acetolactate
C18911  (R)-4-Phosphopantoate
Related
pathway
hsa00010  Glycolysis / Gluconeogenesis
hsa00240  Pyrimidine metabolism
hsa00250  Alanine, aspartate and glutamate metabolism
hsa00270  Cysteine and methionine metabolism
hsa00330  Arginine and proline metabolism
hsa00410  beta-Alanine metabolism
hsa00640  Propanoate metabolism
KO pathway
ko00770   

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