KEGG   Homo sapiens (human): 1432
Entry
1432              CDS       T01001                                 
Symbol
MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA
Name
(RefSeq) mitogen-activated protein kinase 14
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
hsa  Homo sapiens (human)
Pathway
hsa01522  Endocrine resistance
hsa04010  MAPK signaling pathway
hsa04015  Rap1 signaling pathway
hsa04068  FoxO signaling pathway
hsa04071  Sphingolipid signaling pathway
hsa04114  Oocyte meiosis
hsa04148  Efferocytosis
hsa04218  Cellular senescence
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04370  VEGF signaling pathway
hsa04380  Osteoclast differentiation
hsa04550  Signaling pathways regulating pluripotency of stem cells
hsa04611  Platelet activation
hsa04613  Neutrophil extracellular trap formation
hsa04620  Toll-like receptor signaling pathway
hsa04621  NOD-like receptor signaling pathway
hsa04622  RIG-I-like receptor signaling pathway
hsa04625  C-type lectin receptor signaling pathway
hsa04657  IL-17 signaling pathway
hsa04658  Th1 and Th2 cell differentiation
hsa04659  Th17 cell differentiation
hsa04660  T cell receptor signaling pathway
hsa04664  Fc epsilon RI signaling pathway
hsa04668  TNF signaling pathway
hsa04670  Leukocyte transendothelial migration
hsa04714  Thermogenesis
hsa04722  Neurotrophin signaling pathway
hsa04723  Retrograde endocannabinoid signaling
hsa04728  Dopaminergic synapse
hsa04750  Inflammatory mediator regulation of TRP channels
hsa04912  GnRH signaling pathway
hsa04914  Progesterone-mediated oocyte maturation
hsa04917  Prolactin signaling pathway
hsa04926  Relaxin signaling pathway
hsa04932  Non-alcoholic fatty liver disease
hsa04933  AGE-RAGE signaling pathway in diabetic complications
hsa04935  Growth hormone synthesis, secretion and action
hsa04936  Alcoholic liver disease
hsa05014  Amyotrophic lateral sclerosis
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05120  Epithelial cell signaling in Helicobacter pylori infection
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05133  Pertussis
hsa05135  Yersinia infection
hsa05140  Leishmaniasis
hsa05142  Chagas disease
hsa05145  Toxoplasmosis
hsa05152  Tuberculosis
hsa05161  Hepatitis B
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05169  Epstein-Barr virus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05171  Coronavirus disease - COVID-19
hsa05205  Proteoglycans in cancer
hsa05208  Chemical carcinogenesis - reactive oxygen species
hsa05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
hsa05415  Diabetic cardiomyopathy
hsa05417  Lipid and atherosclerosis
hsa05418  Fluid shear stress and atherosclerosis
Network
nt06161  Human immunodeficiency virus 1 (HIV-1)
nt06162  Hepatitis B virus (HBV)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06180  Pathogenic Escherichia coli
nt06182  Shigella
nt06183  Yersinia
nt06211  Other MAPK signaling (cancer)
nt06263  Hepatocellular carcinoma
nt06516  TNF signaling
nt06517  TLR signaling
nt06526  MAPK signaling
nt06535  Efferocytosis
  Element
N00186  IL1-IL1R-p38 signaling pathway
N00187  KSHV Kaposin B to p38 signaling pathway
N00438  TLR2/4-MAPK signaling pathway
N00444  TNF-p38 signaling pathway
N00445  HIV Tat/Nef to TNF-p38 signaling pathway
N00931  Escherichia NleD to TNF-p38 signaling pathway
N01283  Shigella OspF to TLR2/4-MAPK signaling pathway
N01593  Regulation of GF-RTK-RAS-ERK signaling, PTP
N01776  CaMK2-p38-MK2-ALOX5 pathway
Drug target
Dilmapimod (DG01409): D09602 D09603
Doramapimod: D03736
Losmapimod: D09639
Neflamapimod: D10959
Pamapimod: D08963
Ralimetinib (DG01847): D10658 D10659
Talmapimod: D09386
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    1432 (MAPK14)
   04015 Rap1 signaling pathway
    1432 (MAPK14)
   04370 VEGF signaling pathway
    1432 (MAPK14)
   04668 TNF signaling pathway
    1432 (MAPK14)
   04068 FoxO signaling pathway
    1432 (MAPK14)
   04071 Sphingolipid signaling pathway
    1432 (MAPK14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    1432 (MAPK14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    1432 (MAPK14)
   04218 Cellular senescence
    1432 (MAPK14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    1432 (MAPK14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    1432 (MAPK14)
   04613 Neutrophil extracellular trap formation
    1432 (MAPK14)
   04620 Toll-like receptor signaling pathway
    1432 (MAPK14)
   04621 NOD-like receptor signaling pathway
    1432 (MAPK14)
   04622 RIG-I-like receptor signaling pathway
    1432 (MAPK14)
   04625 C-type lectin receptor signaling pathway
    1432 (MAPK14)
   04660 T cell receptor signaling pathway
    1432 (MAPK14)
   04658 Th1 and Th2 cell differentiation
    1432 (MAPK14)
   04659 Th17 cell differentiation
    1432 (MAPK14)
   04657 IL-17 signaling pathway
    1432 (MAPK14)
   04664 Fc epsilon RI signaling pathway
    1432 (MAPK14)
   04670 Leukocyte transendothelial migration
    1432 (MAPK14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    1432 (MAPK14)
   04914 Progesterone-mediated oocyte maturation
    1432 (MAPK14)
   04917 Prolactin signaling pathway
    1432 (MAPK14)
   04926 Relaxin signaling pathway
    1432 (MAPK14)
   04935 Growth hormone synthesis, secretion and action
    1432 (MAPK14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    1432 (MAPK14)
  09156 Nervous system
   04728 Dopaminergic synapse
    1432 (MAPK14)
   04723 Retrograde endocannabinoid signaling
    1432 (MAPK14)
   04722 Neurotrophin signaling pathway
    1432 (MAPK14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    1432 (MAPK14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    1432 (MAPK14)
  09159 Environmental adaptation
   04714 Thermogenesis
    1432 (MAPK14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    1432 (MAPK14)
   05208 Chemical carcinogenesis - reactive oxygen species
    1432 (MAPK14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    1432 (MAPK14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    1432 (MAPK14)
   05161 Hepatitis B
    1432 (MAPK14)
   05171 Coronavirus disease - COVID-19
    1432 (MAPK14)
   05163 Human cytomegalovirus infection
    1432 (MAPK14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    1432 (MAPK14)
   05169 Epstein-Barr virus infection
    1432 (MAPK14)
  09171 Infectious disease: bacterial
   05120 Epithelial cell signaling in Helicobacter pylori infection
    1432 (MAPK14)
   05130 Pathogenic Escherichia coli infection
    1432 (MAPK14)
   05132 Salmonella infection
    1432 (MAPK14)
   05131 Shigellosis
    1432 (MAPK14)
   05135 Yersinia infection
    1432 (MAPK14)
   05133 Pertussis
    1432 (MAPK14)
   05152 Tuberculosis
    1432 (MAPK14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    1432 (MAPK14)
   05140 Leishmaniasis
    1432 (MAPK14)
   05142 Chagas disease
    1432 (MAPK14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    1432 (MAPK14)
   05020 Prion disease
    1432 (MAPK14)
   05022 Pathways of neurodegeneration - multiple diseases
    1432 (MAPK14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    1432 (MAPK14)
   05418 Fluid shear stress and atherosclerosis
    1432 (MAPK14)
   05415 Diabetic cardiomyopathy
    1432 (MAPK14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    1432 (MAPK14)
   04932 Non-alcoholic fatty liver disease
    1432 (MAPK14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    1432 (MAPK14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    1432 (MAPK14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    1432 (MAPK14)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     1432 (MAPK14)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   1432 (MAPK14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH NAD_binding_8
Other DBs
NCBI-GeneID: 1432
NCBI-ProteinID: NP_001306
OMIM: 600289
HGNC: 6876
Ensembl: ENSG00000112062
UniProt: Q16539 L7RSM2
Structure
LinkDB
Position
6:36027808..36124214
AA seq 360 aa
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG
TPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
NT seq 1083 nt   +upstreamnt  +downstreamnt
atgtctcaggagaggcccacgttctaccggcaggagctgaacaagacaatctgggaggtg
cccgagcgttaccagaacctgtctccagtgggctctggcgcctatggctctgtgtgtgct
gcttttgacacaaaaacggggttacgtgtggcagtgaagaagctctccagaccatttcag
tccatcattcatgcgaaaagaacctacagagaactgcggttacttaaacatatgaaacat
gaaaatgtgattggtctgttggacgtttttacacctgcaaggtctctggaggaattcaat
gatgtgtatctggtgacccatctcatgggggcagatctgaacaacattgtgaaatgtcag
aagcttacagatgaccatgttcagttccttatctaccaaattctccgaggtctaaagtat
atacattcagctgacataattcacagggacctaaaacctagtaatctagctgtgaatgaa
gactgtgagctgaagattctggattttggactggctcggcacacagatgatgaaatgaca
ggctacgtggccactaggtggtacagggctcctgagatcatgctgaactggatgcattac
aaccagacagttgatatttggtcagtgggatgcataatggccgagctgttgactggaaga
acattgtttcctggtacagaccatattaaccagcttcagcagattatgcgtctgacagga
acaccccccgcttatctcattaacaggatgccaagccatgaggcaagaaactatattcag
tctttgactcagatgccgaagatgaactttgcgaatgtatttattggtgccaatcccctg
gctgtcgacttgctggagaagatgcttgtattggactcagataagagaattacagcggcc
caagcccttgcacatgcctactttgctcagtaccacgatcctgatgatgaaccagtggcc
gatccttatgatcagtcctttgaaagcagggacctccttatagatgagtggaaaagcctg
acctatgatgaagtcatcagctttgtgccaccaccccttgaccaagaagagatggagtcc
tga

KEGG   Homo sapiens (human): 5600
Entry
5600              CDS       T01001                                 
Symbol
MAPK11, P38B, P38BETA2, PRKM11, SAPK2, SAPK2B, p38-2, p38Beta
Name
(RefSeq) mitogen-activated protein kinase 11
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
hsa  Homo sapiens (human)
Pathway
hsa01522  Endocrine resistance
hsa04010  MAPK signaling pathway
hsa04015  Rap1 signaling pathway
hsa04068  FoxO signaling pathway
hsa04071  Sphingolipid signaling pathway
hsa04114  Oocyte meiosis
hsa04148  Efferocytosis
hsa04218  Cellular senescence
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04370  VEGF signaling pathway
hsa04380  Osteoclast differentiation
hsa04550  Signaling pathways regulating pluripotency of stem cells
hsa04611  Platelet activation
hsa04613  Neutrophil extracellular trap formation
hsa04620  Toll-like receptor signaling pathway
hsa04621  NOD-like receptor signaling pathway
hsa04622  RIG-I-like receptor signaling pathway
hsa04625  C-type lectin receptor signaling pathway
hsa04657  IL-17 signaling pathway
hsa04658  Th1 and Th2 cell differentiation
hsa04659  Th17 cell differentiation
hsa04660  T cell receptor signaling pathway
hsa04664  Fc epsilon RI signaling pathway
hsa04668  TNF signaling pathway
hsa04670  Leukocyte transendothelial migration
hsa04714  Thermogenesis
hsa04722  Neurotrophin signaling pathway
hsa04723  Retrograde endocannabinoid signaling
hsa04728  Dopaminergic synapse
hsa04750  Inflammatory mediator regulation of TRP channels
hsa04912  GnRH signaling pathway
hsa04914  Progesterone-mediated oocyte maturation
hsa04917  Prolactin signaling pathway
hsa04926  Relaxin signaling pathway
hsa04932  Non-alcoholic fatty liver disease
hsa04933  AGE-RAGE signaling pathway in diabetic complications
hsa04935  Growth hormone synthesis, secretion and action
hsa04936  Alcoholic liver disease
hsa05014  Amyotrophic lateral sclerosis
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05120  Epithelial cell signaling in Helicobacter pylori infection
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05133  Pertussis
hsa05135  Yersinia infection
hsa05140  Leishmaniasis
hsa05142  Chagas disease
hsa05145  Toxoplasmosis
hsa05152  Tuberculosis
hsa05161  Hepatitis B
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05169  Epstein-Barr virus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05171  Coronavirus disease - COVID-19
hsa05205  Proteoglycans in cancer
hsa05208  Chemical carcinogenesis - reactive oxygen species
hsa05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
hsa05415  Diabetic cardiomyopathy
hsa05417  Lipid and atherosclerosis
hsa05418  Fluid shear stress and atherosclerosis
Network
nt06161  Human immunodeficiency virus 1 (HIV-1)
nt06162  Hepatitis B virus (HBV)
nt06180  Pathogenic Escherichia coli
nt06182  Shigella
nt06183  Yersinia
nt06263  Hepatocellular carcinoma
nt06517  TLR signaling
nt06535  Efferocytosis
  Element
N00438  TLR2/4-MAPK signaling pathway
N01283  Shigella OspF to TLR2/4-MAPK signaling pathway
N01776  CaMK2-p38-MK2-ALOX5 pathway
Drug target
Dilmapimod (DG01409): D09602 D09603
Doramapimod: D03736
Losmapimod: D09639
Neflamapimod: D10959
Ralimetinib (DG01847): D10658 D10659
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    5600 (MAPK11)
   04015 Rap1 signaling pathway
    5600 (MAPK11)
   04370 VEGF signaling pathway
    5600 (MAPK11)
   04668 TNF signaling pathway
    5600 (MAPK11)
   04068 FoxO signaling pathway
    5600 (MAPK11)
   04071 Sphingolipid signaling pathway
    5600 (MAPK11)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    5600 (MAPK11)
  09143 Cell growth and death
   04114 Oocyte meiosis
    5600 (MAPK11)
   04218 Cellular senescence
    5600 (MAPK11)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    5600 (MAPK11)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    5600 (MAPK11)
   04613 Neutrophil extracellular trap formation
    5600 (MAPK11)
   04620 Toll-like receptor signaling pathway
    5600 (MAPK11)
   04621 NOD-like receptor signaling pathway
    5600 (MAPK11)
   04622 RIG-I-like receptor signaling pathway
    5600 (MAPK11)
   04625 C-type lectin receptor signaling pathway
    5600 (MAPK11)
   04660 T cell receptor signaling pathway
    5600 (MAPK11)
   04658 Th1 and Th2 cell differentiation
    5600 (MAPK11)
   04659 Th17 cell differentiation
    5600 (MAPK11)
   04657 IL-17 signaling pathway
    5600 (MAPK11)
   04664 Fc epsilon RI signaling pathway
    5600 (MAPK11)
   04670 Leukocyte transendothelial migration
    5600 (MAPK11)
  09152 Endocrine system
   04912 GnRH signaling pathway
    5600 (MAPK11)
   04914 Progesterone-mediated oocyte maturation
    5600 (MAPK11)
   04917 Prolactin signaling pathway
    5600 (MAPK11)
   04926 Relaxin signaling pathway
    5600 (MAPK11)
   04935 Growth hormone synthesis, secretion and action
    5600 (MAPK11)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    5600 (MAPK11)
  09156 Nervous system
   04728 Dopaminergic synapse
    5600 (MAPK11)
   04723 Retrograde endocannabinoid signaling
    5600 (MAPK11)
   04722 Neurotrophin signaling pathway
    5600 (MAPK11)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    5600 (MAPK11)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    5600 (MAPK11)
  09159 Environmental adaptation
   04714 Thermogenesis
    5600 (MAPK11)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    5600 (MAPK11)
   05208 Chemical carcinogenesis - reactive oxygen species
    5600 (MAPK11)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    5600 (MAPK11)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    5600 (MAPK11)
   05161 Hepatitis B
    5600 (MAPK11)
   05171 Coronavirus disease - COVID-19
    5600 (MAPK11)
   05163 Human cytomegalovirus infection
    5600 (MAPK11)
   05167 Kaposi sarcoma-associated herpesvirus infection
    5600 (MAPK11)
   05169 Epstein-Barr virus infection
    5600 (MAPK11)
  09171 Infectious disease: bacterial
   05120 Epithelial cell signaling in Helicobacter pylori infection
    5600 (MAPK11)
   05130 Pathogenic Escherichia coli infection
    5600 (MAPK11)
   05132 Salmonella infection
    5600 (MAPK11)
   05131 Shigellosis
    5600 (MAPK11)
   05135 Yersinia infection
    5600 (MAPK11)
   05133 Pertussis
    5600 (MAPK11)
   05152 Tuberculosis
    5600 (MAPK11)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    5600 (MAPK11)
   05140 Leishmaniasis
    5600 (MAPK11)
   05142 Chagas disease
    5600 (MAPK11)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    5600 (MAPK11)
   05020 Prion disease
    5600 (MAPK11)
   05022 Pathways of neurodegeneration - multiple diseases
    5600 (MAPK11)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    5600 (MAPK11)
   05418 Fluid shear stress and atherosclerosis
    5600 (MAPK11)
   05415 Diabetic cardiomyopathy
    5600 (MAPK11)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    5600 (MAPK11)
   04932 Non-alcoholic fatty liver disease
    5600 (MAPK11)
   04933 AGE-RAGE signaling pathway in diabetic complications
    5600 (MAPK11)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    5600 (MAPK11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    5600 (MAPK11)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     5600 (MAPK11)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   5600 (MAPK11)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH RIO1 Cas_CT1975
Other DBs
NCBI-GeneID: 5600
NCBI-ProteinID: NP_002742
OMIM: 602898
HGNC: 6873
Ensembl: ENSG00000185386
UniProt: Q15759
Structure
LinkDB
Position
22:complement(50263713..50270380)
AA seq 364 aa
MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAA
EALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSL
EIEQ
NT seq 1095 nt   +upstreamnt  +downstreamnt
atgtcgggccctcgcgccggcttctaccggcaggagctgaacaagaccgtgtgggaggtg
ccgcagcggctgcaggggctgcgcccggtgggctccggcgcctacggctccgtctgttcg
gcctacgacgcccggctgcgccagaaggtggcggtgaagaagctgtcgcgccccttccag
tcgctgatccacgcgcgcagaacgtaccgggagctgcggctgctcaagcacctgaagcac
gagaacgtcatcgggcttctggacgtcttcacgccggccacgtccatcgaggacttcagc
gaagtgtacttggtgaccaccctgatgggcgccgacctgaacaacatcgtcaagtgccag
gcgctgagcgacgagcacgttcaattcctggtttaccagctgctgcgcgggctgaagtac
atccactcggccgggatcatccaccgggacctgaagcccagcaacgtggctgtgaacgag
gactgtgagctcaggatcctggattttgggctggcgcgccaggcggacgaggagatgacc
ggctatgtggccacgcgctggtaccgggcacctgagatcatgctcaactggatgcattac
aaccaaacagtggatatctggtccgtgggctgcatcatggctgagctgctccagggcaag
gccctcttcccgggaagcgactacattgaccagctgaagcgcatcatggaagtggtgggc
acacccagccctgaggttctggcaaaaatctcctcagaacacgcccggacatatatccag
tccctgccccccatgccccagaaggacctgagcagcatcttccgtggagccaaccccctg
gccatagacctccttggaaggatgctggtgctggacagtgaccagagggtcagtgcagct
gaggcactggcccacgcctacttcagccagtaccacgaccccgaggatgagccagaggcc
gagccatatgatgagagcgttgaggccaaggagcgcacgctggaggagtggaaggagctc
acttaccaggaagtcctcagcttcaagcccccagagccaccgaagccacctggcagcctg
gagattgagcagtga

KEGG   Homo sapiens (human): 5603
Entry
5603              CDS       T01001                                 
Symbol
MAPK13, MAPK_13, MAPK-13, PRKM13, SAPK4, p38delta
Name
(RefSeq) mitogen-activated protein kinase 13
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
hsa  Homo sapiens (human)
Pathway
hsa01522  Endocrine resistance
hsa04010  MAPK signaling pathway
hsa04015  Rap1 signaling pathway
hsa04068  FoxO signaling pathway
hsa04071  Sphingolipid signaling pathway
hsa04114  Oocyte meiosis
hsa04148  Efferocytosis
hsa04218  Cellular senescence
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04370  VEGF signaling pathway
hsa04380  Osteoclast differentiation
hsa04550  Signaling pathways regulating pluripotency of stem cells
hsa04611  Platelet activation
hsa04613  Neutrophil extracellular trap formation
hsa04620  Toll-like receptor signaling pathway
hsa04621  NOD-like receptor signaling pathway
hsa04622  RIG-I-like receptor signaling pathway
hsa04625  C-type lectin receptor signaling pathway
hsa04657  IL-17 signaling pathway
hsa04658  Th1 and Th2 cell differentiation
hsa04659  Th17 cell differentiation
hsa04660  T cell receptor signaling pathway
hsa04664  Fc epsilon RI signaling pathway
hsa04668  TNF signaling pathway
hsa04670  Leukocyte transendothelial migration
hsa04714  Thermogenesis
hsa04722  Neurotrophin signaling pathway
hsa04723  Retrograde endocannabinoid signaling
hsa04728  Dopaminergic synapse
hsa04750  Inflammatory mediator regulation of TRP channels
hsa04912  GnRH signaling pathway
hsa04914  Progesterone-mediated oocyte maturation
hsa04917  Prolactin signaling pathway
hsa04926  Relaxin signaling pathway
hsa04932  Non-alcoholic fatty liver disease
hsa04933  AGE-RAGE signaling pathway in diabetic complications
hsa04935  Growth hormone synthesis, secretion and action
hsa04936  Alcoholic liver disease
hsa05014  Amyotrophic lateral sclerosis
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05120  Epithelial cell signaling in Helicobacter pylori infection
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05133  Pertussis
hsa05135  Yersinia infection
hsa05140  Leishmaniasis
hsa05142  Chagas disease
hsa05145  Toxoplasmosis
hsa05152  Tuberculosis
hsa05161  Hepatitis B
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05169  Epstein-Barr virus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05171  Coronavirus disease - COVID-19
hsa05205  Proteoglycans in cancer
hsa05208  Chemical carcinogenesis - reactive oxygen species
hsa05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
hsa05415  Diabetic cardiomyopathy
hsa05417  Lipid and atherosclerosis
hsa05418  Fluid shear stress and atherosclerosis
Network
nt06161  Human immunodeficiency virus 1 (HIV-1)
nt06162  Hepatitis B virus (HBV)
nt06180  Pathogenic Escherichia coli
nt06182  Shigella
nt06183  Yersinia
nt06263  Hepatocellular carcinoma
nt06517  TLR signaling
nt06535  Efferocytosis
  Element
N00438  TLR2/4-MAPK signaling pathway
N01283  Shigella OspF to TLR2/4-MAPK signaling pathway
N01776  CaMK2-p38-MK2-ALOX5 pathway
Drug target
Dilmapimod (DG01409): D09602 D09603
Doramapimod: D03736
Losmapimod: D09639
Neflamapimod: D10959
Ralimetinib (DG01847): D10658 D10659
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    5603 (MAPK13)
   04015 Rap1 signaling pathway
    5603 (MAPK13)
   04370 VEGF signaling pathway
    5603 (MAPK13)
   04668 TNF signaling pathway
    5603 (MAPK13)
   04068 FoxO signaling pathway
    5603 (MAPK13)
   04071 Sphingolipid signaling pathway
    5603 (MAPK13)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    5603 (MAPK13)
  09143 Cell growth and death
   04114 Oocyte meiosis
    5603 (MAPK13)
   04218 Cellular senescence
    5603 (MAPK13)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    5603 (MAPK13)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    5603 (MAPK13)
   04613 Neutrophil extracellular trap formation
    5603 (MAPK13)
   04620 Toll-like receptor signaling pathway
    5603 (MAPK13)
   04621 NOD-like receptor signaling pathway
    5603 (MAPK13)
   04622 RIG-I-like receptor signaling pathway
    5603 (MAPK13)
   04625 C-type lectin receptor signaling pathway
    5603 (MAPK13)
   04660 T cell receptor signaling pathway
    5603 (MAPK13)
   04658 Th1 and Th2 cell differentiation
    5603 (MAPK13)
   04659 Th17 cell differentiation
    5603 (MAPK13)
   04657 IL-17 signaling pathway
    5603 (MAPK13)
   04664 Fc epsilon RI signaling pathway
    5603 (MAPK13)
   04670 Leukocyte transendothelial migration
    5603 (MAPK13)
  09152 Endocrine system
   04912 GnRH signaling pathway
    5603 (MAPK13)
   04914 Progesterone-mediated oocyte maturation
    5603 (MAPK13)
   04917 Prolactin signaling pathway
    5603 (MAPK13)
   04926 Relaxin signaling pathway
    5603 (MAPK13)
   04935 Growth hormone synthesis, secretion and action
    5603 (MAPK13)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    5603 (MAPK13)
  09156 Nervous system
   04728 Dopaminergic synapse
    5603 (MAPK13)
   04723 Retrograde endocannabinoid signaling
    5603 (MAPK13)
   04722 Neurotrophin signaling pathway
    5603 (MAPK13)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    5603 (MAPK13)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    5603 (MAPK13)
  09159 Environmental adaptation
   04714 Thermogenesis
    5603 (MAPK13)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    5603 (MAPK13)
   05208 Chemical carcinogenesis - reactive oxygen species
    5603 (MAPK13)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    5603 (MAPK13)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    5603 (MAPK13)
   05161 Hepatitis B
    5603 (MAPK13)
   05171 Coronavirus disease - COVID-19
    5603 (MAPK13)
   05163 Human cytomegalovirus infection
    5603 (MAPK13)
   05167 Kaposi sarcoma-associated herpesvirus infection
    5603 (MAPK13)
   05169 Epstein-Barr virus infection
    5603 (MAPK13)
  09171 Infectious disease: bacterial
   05120 Epithelial cell signaling in Helicobacter pylori infection
    5603 (MAPK13)
   05130 Pathogenic Escherichia coli infection
    5603 (MAPK13)
   05132 Salmonella infection
    5603 (MAPK13)
   05131 Shigellosis
    5603 (MAPK13)
   05135 Yersinia infection
    5603 (MAPK13)
   05133 Pertussis
    5603 (MAPK13)
   05152 Tuberculosis
    5603 (MAPK13)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    5603 (MAPK13)
   05140 Leishmaniasis
    5603 (MAPK13)
   05142 Chagas disease
    5603 (MAPK13)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    5603 (MAPK13)
   05020 Prion disease
    5603 (MAPK13)
   05022 Pathways of neurodegeneration - multiple diseases
    5603 (MAPK13)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    5603 (MAPK13)
   05418 Fluid shear stress and atherosclerosis
    5603 (MAPK13)
   05415 Diabetic cardiomyopathy
    5603 (MAPK13)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    5603 (MAPK13)
   04932 Non-alcoholic fatty liver disease
    5603 (MAPK13)
   04933 AGE-RAGE signaling pathway in diabetic complications
    5603 (MAPK13)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    5603 (MAPK13)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    5603 (MAPK13)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     5603 (MAPK13)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   5603 (MAPK13)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH RIO1 Kdo Kinase-like US2
Other DBs
NCBI-GeneID: 5603
NCBI-ProteinID: NP_002745
OMIM: 602899
HGNC: 6875
Ensembl: ENSG00000156711
UniProt: O15264 A0A024RD04
Structure
LinkDB
Position
6:36130513..36144521
AA seq 365 aa
MSLIRKKGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPF
QSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIMGM
EFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEMT
GYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTG
VPGTEFVQKLNDKAAKSYIQSLPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAA
QALTHPFFEPFRDPEEETEAQQPFDDSLEHEKLTVDEWKQHIYKEIVNFSPIARKDSRRR
SGMKL
NT seq 1098 nt   +upstreamnt  +downstreamnt
atgagcctcatccggaaaaagggcttctacaagcaggacgtcaacaagacagcctgggag
ctgcccaagacctacgtgtccccgacgcacgtcggcagcggggcctatggctccgtgtgc
tcggccatcgacaagcggtcaggggagaaggtggccatcaagaagctgagccgacccttt
cagtccgagatcttcgccaagcgcgcctaccgggagctgctgctgctgaagcacatgcag
catgagaacgtcattgggctcctggatgtcttcaccccagcctcctccctgcgcaacttc
tatgacttctacctggtgatgcccttcatgcagacggatctgcagaagatcatggggatg
gagttcagtgaggagaagatccagtacctggtgtatcagatgctcaaaggccttaagtac
atccactctgctggggtcgtgcacagggacctgaagccaggcaacctggctgtgaatgag
gactgtgaactgaagattctggattttgggctggcgcgacatgcagacgccgagatgact
ggctacgtggtgacccgctggtaccgagcccccgaggtgatcctcagctggatgcactac
aaccagacagtggacatctggtctgtgggctgtatcatggcagagatgctgacagggaaa
actctgttcaaggggaaagattacctggaccagctgacccagatcctgaaagtgaccggg
gtgcctggcacggagtttgtgcagaagctgaacgacaaagcggccaaatcctacatccag
tccctgccacagacccccaggaaggatttcactcagctgttcccacgggccagcccccag
gctgcggacctgctggagaagatgctggagctagacgtggacaagcgcctgacggccgcg
caggccctcacccatcccttctttgaacccttccgggaccctgaggaagagacggaggcc
cagcagccgtttgatgattccttagaacacgagaaactcacagtggatgaatggaagcag
cacatctacaaggagattgtgaacttcagccccattgcccggaaggactcacggcgccgg
agtggcatgaagctgtag

KEGG   Homo sapiens (human): 6300
Entry
6300              CDS       T01001                                 
Symbol
MAPK12, ERK-6, ERK3, ERK6, MAPK_12, P38GAMMA, PRKM12, SAPK-3, SAPK3
Name
(RefSeq) mitogen-activated protein kinase 12
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
hsa  Homo sapiens (human)
Pathway
hsa01522  Endocrine resistance
hsa04010  MAPK signaling pathway
hsa04015  Rap1 signaling pathway
hsa04068  FoxO signaling pathway
hsa04071  Sphingolipid signaling pathway
hsa04114  Oocyte meiosis
hsa04148  Efferocytosis
hsa04218  Cellular senescence
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04370  VEGF signaling pathway
hsa04380  Osteoclast differentiation
hsa04550  Signaling pathways regulating pluripotency of stem cells
hsa04611  Platelet activation
hsa04613  Neutrophil extracellular trap formation
hsa04620  Toll-like receptor signaling pathway
hsa04621  NOD-like receptor signaling pathway
hsa04622  RIG-I-like receptor signaling pathway
hsa04625  C-type lectin receptor signaling pathway
hsa04657  IL-17 signaling pathway
hsa04658  Th1 and Th2 cell differentiation
hsa04659  Th17 cell differentiation
hsa04660  T cell receptor signaling pathway
hsa04664  Fc epsilon RI signaling pathway
hsa04668  TNF signaling pathway
hsa04670  Leukocyte transendothelial migration
hsa04714  Thermogenesis
hsa04722  Neurotrophin signaling pathway
hsa04723  Retrograde endocannabinoid signaling
hsa04728  Dopaminergic synapse
hsa04750  Inflammatory mediator regulation of TRP channels
hsa04912  GnRH signaling pathway
hsa04914  Progesterone-mediated oocyte maturation
hsa04917  Prolactin signaling pathway
hsa04926  Relaxin signaling pathway
hsa04932  Non-alcoholic fatty liver disease
hsa04933  AGE-RAGE signaling pathway in diabetic complications
hsa04935  Growth hormone synthesis, secretion and action
hsa04936  Alcoholic liver disease
hsa05014  Amyotrophic lateral sclerosis
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05120  Epithelial cell signaling in Helicobacter pylori infection
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05133  Pertussis
hsa05135  Yersinia infection
hsa05140  Leishmaniasis
hsa05142  Chagas disease
hsa05145  Toxoplasmosis
hsa05152  Tuberculosis
hsa05161  Hepatitis B
hsa05163  Human cytomegalovirus infection
hsa05167  Kaposi sarcoma-associated herpesvirus infection
hsa05169  Epstein-Barr virus infection
hsa05170  Human immunodeficiency virus 1 infection
hsa05171  Coronavirus disease - COVID-19
hsa05205  Proteoglycans in cancer
hsa05208  Chemical carcinogenesis - reactive oxygen species
hsa05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
hsa05415  Diabetic cardiomyopathy
hsa05417  Lipid and atherosclerosis
hsa05418  Fluid shear stress and atherosclerosis
Network
nt06161  Human immunodeficiency virus 1 (HIV-1)
nt06162  Hepatitis B virus (HBV)
nt06180  Pathogenic Escherichia coli
nt06182  Shigella
nt06183  Yersinia
nt06263  Hepatocellular carcinoma
nt06517  TLR signaling
nt06535  Efferocytosis
  Element
N00438  TLR2/4-MAPK signaling pathway
N01283  Shigella OspF to TLR2/4-MAPK signaling pathway
N01776  CaMK2-p38-MK2-ALOX5 pathway
Drug target
Dilmapimod (DG01409): D09602 D09603
Doramapimod: D03736
Losmapimod: D09639
Neflamapimod: D10959
Ralimetinib (DG01847): D10658 D10659
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    6300 (MAPK12)
   04015 Rap1 signaling pathway
    6300 (MAPK12)
   04370 VEGF signaling pathway
    6300 (MAPK12)
   04668 TNF signaling pathway
    6300 (MAPK12)
   04068 FoxO signaling pathway
    6300 (MAPK12)
   04071 Sphingolipid signaling pathway
    6300 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    6300 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    6300 (MAPK12)
   04218 Cellular senescence
    6300 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    6300 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    6300 (MAPK12)
   04613 Neutrophil extracellular trap formation
    6300 (MAPK12)
   04620 Toll-like receptor signaling pathway
    6300 (MAPK12)
   04621 NOD-like receptor signaling pathway
    6300 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    6300 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    6300 (MAPK12)
   04660 T cell receptor signaling pathway
    6300 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    6300 (MAPK12)
   04659 Th17 cell differentiation
    6300 (MAPK12)
   04657 IL-17 signaling pathway
    6300 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    6300 (MAPK12)
   04670 Leukocyte transendothelial migration
    6300 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    6300 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    6300 (MAPK12)
   04917 Prolactin signaling pathway
    6300 (MAPK12)
   04926 Relaxin signaling pathway
    6300 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    6300 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    6300 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    6300 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    6300 (MAPK12)
   04722 Neurotrophin signaling pathway
    6300 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    6300 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    6300 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    6300 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    6300 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    6300 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    6300 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    6300 (MAPK12)
   05161 Hepatitis B
    6300 (MAPK12)
   05171 Coronavirus disease - COVID-19
    6300 (MAPK12)
   05163 Human cytomegalovirus infection
    6300 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    6300 (MAPK12)
   05169 Epstein-Barr virus infection
    6300 (MAPK12)
  09171 Infectious disease: bacterial
   05120 Epithelial cell signaling in Helicobacter pylori infection
    6300 (MAPK12)
   05130 Pathogenic Escherichia coli infection
    6300 (MAPK12)
   05132 Salmonella infection
    6300 (MAPK12)
   05131 Shigellosis
    6300 (MAPK12)
   05135 Yersinia infection
    6300 (MAPK12)
   05133 Pertussis
    6300 (MAPK12)
   05152 Tuberculosis
    6300 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    6300 (MAPK12)
   05140 Leishmaniasis
    6300 (MAPK12)
   05142 Chagas disease
    6300 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    6300 (MAPK12)
   05020 Prion disease
    6300 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    6300 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    6300 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    6300 (MAPK12)
   05415 Diabetic cardiomyopathy
    6300 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    6300 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    6300 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    6300 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    6300 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    6300 (MAPK12)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     6300 (MAPK12)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   6300 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kdo DUF5828 Kinase-like Haspin_kinase Peripla_BP_5
Other DBs
NCBI-GeneID: 6300
NCBI-ProteinID: NP_002960
OMIM: 602399
HGNC: 6874
Ensembl: ENSG00000188130
UniProt: P53778
Structure
LinkDB
Position
22:complement(50252901..50261683)
AA seq 367 aa
MSSPPPARSGFYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KHEKLGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMK
VTGTPPAEFVQRLQSDEAKNYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRV
TAGEALAHPYFESLHDTEDEPQVQKYDDSFDDVDRTLDEWKRVTYKEVLSFKPPRQLGAR
VSKETPL
NT seq 1104 nt   +upstreamnt  +downstreamnt
atgagctctccgccgcccgcccgcagtggcttttaccgccaggaggtgaccaagacggcc
tgggaggtgcgcgccgtgtaccgggacctgcagcccgtgggctcgggcgcctacggcgcg
gtgtgctcggccgtggacggccgcaccggcgctaaggtggccatcaagaagctgtatcgg
cctttccagtccgagctgttcgccaagcgcgcctaccgcgagctgcgcctgctcaagcac
atgcgccacgagaacgtgatcgggctgctggacgtattcactcctgatgagaccctggat
gacttcacggacttttacctggtgatgccgttcatgggcaccgacctgggcaagctcatg
aaacatgagaagctaggcgaggaccggatccagttcctcgtgtaccagatgctgaagggg
ctgaggtatatccacgctgccggcatcatccacagagacctgaagcccggcaacctggct
gtgaacgaagactgtgagctgaagatcctggacttcggcctggccaggcaggcagacagt
gagatgactgggtacgtggtgacccggtggtaccgggctcccgaggtcatcttgaattgg
atgcgctacacgcagacggtggacatctggtctgtgggctgcatcatggcggagatgatc
acaggcaagacgctgttcaagggcagcgaccacctggaccagctgaaggagatcatgaag
gtgacggggacgcctccggctgagtttgtgcagcggctgcagagcgatgaggccaagaac
tacatgaagggcctccccgaattggagaagaaggattttgcctctatcctgaccaatgca
agccctctggctgtgaacctcctggagaagatgctggtgctggacgcggagcagcgggtg
acggcaggcgaggcgctggcccatccctacttcgagtccctgcacgacacggaagatgag
ccccaggtccagaagtatgatgactcctttgacgacgttgaccgcacactggatgaatgg
aagcgtgttacttacaaagaggtgctcagcttcaagcctccccggcagctgggggccagg
gtctccaaggagacgcctctgtga

DBGET integrated database retrieval system