Homo sapiens (human): 239 Help Entry 239               CDS       T01001                                  Symbol ALOX12, 12-LOX, 12S-LOX, LOG12 Name (RefSeq) arachidonate 12-lipoxygenase, 12S type   KO K00458   arachidonate 12-lipoxygenase [EC:1.13.11.31] Organism hsa  Homo sapiens (human) Pathway hsa00590   Arachidonic acid metabolism hsa01100   Metabolic pathways hsa01523   Antifolate resistance hsa04726   Serotonergic synapse hsa04750   Inflammatory mediator regulation of TRP channels Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00590 Arachidonic acid metabolism     239 (ALOX12)  09150 Organismal Systems   09156 Nervous system    04726 Serotonergic synapse     239 (ALOX12)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     239 (ALOX12)  09160 Human Diseases   09176 Drug resistance: antineoplastic    01523 Antifolate resistance     239 (ALOX12) Enzymes [BR:hsa01000]  1. Oxidoreductases   1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)    1.13.11  With incorporation of two atoms of oxygen     1.13.11.31  arachidonate 12-lipoxygenase      239 (ALOX12) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Lipoxygenase PLAT Motif Other DBs NCBI-GeneID:  239 NCBI-ProteinID:  NP_000688 OMIM:  152391 HGNC:  429 Ensembl:  ENSG00000108839 UniProt:  P18054 Structure PDB LinkDB All DBs Position 17:6996049..7010754 Genome browser AA seq 663 aa AA seqDB search MGRYRIRVATGAWLFSGSYNRVQLWLVGTRGEAELELQLRPARGEEEEFDHDVAEDLGLL QFVRLRKHHWLVDDAWFCDRITVQGPGACAEVAFPCYRWVQGEDILSLPEGTARLPGDNA LDMFQKHREKELKDRQQIYCWATWKEGLPLTIAADRKDDLPPNMRFHEEKRLDFEWTLKA GALEMALKRVYTLLSSWNCLEDFDQIFWGQKSALAEKVRQCWQDDELFSYQFLNGANPML LRRSTSLPSRLVLPSGMEELQAQLEKELQNGSLFEADFILLDGIPANVIRGEKQYLAAPL VMLKMEPNGKLQPMVIQIQPPNPSSPTPTLFLPSDPPLAWLLAKSWVRNSDFQLHEIQYH LLNTHLVAEVIAVATMRCLPGLHPIFKFLIPHIRYTMEINTRARTQLISDGGIFDKAVST GGGGHVQLLRRAAAQLTYCSLCPPDDLADRGLLGLPGALYAHDALRLWEIIARYVEGIVH LFYQRDDIVKGDPELQAWCREITEVGLCQAQDRGFPVSFQSQSQLCHFLTMCVFTCTAQH AAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDVRQACLQMAISWHLSRR QPDMVPLGHHKEKYFSGPKPKAVLNQFRTDLEKLEKEITARNEQLDWPYEYLKPSCIENS VTI NT seq 1992 nt NT seq  +upstreamnt  +downstreamnt atgggccgctaccgcatccgcgtggccaccggggcctggctcttctccgggtcgtacaac cgcgtgcagctttggctggtcgggacgcgcggggaggcggagctggagctgcagctgcgg cccgcgcggggcgaggaggaggagtttgatcatgacgttgcagaggacttggggctcctg cagttcgtgaggctgcgcaagcaccactggctggtggacgacgcgtggttctgcgaccgc atcacggtgcagggccctggagcctgcgcggaggtggccttcccgtgctaccgctgggtg cagggcgaggacatcctgagcctgcccgagggcaccgcccgcctgccaggagacaatgct ttggacatgttccagaagcatcgagagaaggaactgaaagacagacagcagatctactgc tgggccacctggaaggaagggttacccctgaccatcgctgcagaccgtaaggatgatcta cctccaaatatgagattccatgaggagaagaggctggactttgaatggacactgaaggca ggggctctggagatggccctcaaacgtgtttacaccctcctgagctcctggaactgccta gaagactttgatcagatcttctggggccagaagagtgccctggctgagaaggttcgccag tgctggcaggatgatgagttgttcagctaccagttcctcaatggtgccaaccccatgctg ttgagacgctcgacctctctgccctccaggctagtgctgccctcggggatggaagagctt caggctcaactggagaaagaacttcagaatggttccctgtttgaagctgacttcatcctt ctggatggaattccagccaacgtgatccgaggagagaagcaatacctggctgcccccctc gttatgctgaagatggagcccaatgggaagctgcagcccatggtcatccagattcagcct cccaaccccagctctccaaccccaacactgttcctgccctcagaccccccacttgcctgg ctcctggcaaagtcctgggtccgaaattcagatttccaactgcacgagatccagtatcac ttgctgaacactcacctggtggctgaggtcatcgctgtcgccaccatgcggtgcctccca ggactgcaccccatcttcaagttcctgatcccccatatccgctacaccatggaaatcaac acccgggcccggacccaactcatctcagatggaggaatttttgataaggcagtgagcaca ggtggagggggccatgtacagttgctccgtcgggcggcagctcagctgacctactgctcc ctctgtcctcctgacgacctggctgaccggggcctgctgggactcccaggtgctctctat gcccatgatgctttacggctctgggagatcattgccaggtatgtggaggggatcgtccac ctcttctaccaaagggatgacatagtgaagggggaccctgagctgcaggcctggtgtcgg gagatcacggaggtggggctgtgccaggcccaggaccgaggtttccctgtctccttccag tcccagagtcaactctgccatttcctcaccatgtgcgtcttcacgtgcactgcccagcat gccgccatcaaccagggccagctggactggtatgcctgggtccctaatgctccatgcaca atgcggatgcccccacccaccaccaaggaagatgtgacgatggccacagtgatggggtca ctacctgatgtccggcaggcctgtcttcaaatggccatctcatggcatctgagtcgccgc cagccagacatggtgcctctggggcaccacaaagaaaaatatttctcaggccccaagccc aaagctgtgctaaaccaattccgaacagatttggaaaagctggaaaaggagattacagcc cggaatgagcaacttgactggccctatgaatatctgaagcccagctgcatagagaacagt gtcaccatctga

Homo sapiens (human): 240 Help Entry 240               CDS       T01001                                  Symbol ALOX5, 5-LO, 5-LOX, 5LPG, LOG5 Name (RefSeq) arachidonate 5-lipoxygenase   KO K00461   arachidonate 5-lipoxygenase [EC:1.13.11.34] Organism hsa  Homo sapiens (human) Pathway hsa00590   Arachidonic acid metabolism hsa01100   Metabolic pathways hsa04148   Efferocytosis hsa04664   Fc epsilon RI signaling pathway hsa04726   Serotonergic synapse hsa04913   Ovarian steroidogenesis hsa05145   Toxoplasmosis Network nt06535  Efferocytosis   Element N01776   CaMK2-p38-MK2-ALOX5 pathway Disease H00079   Asthma Drug target Atreleuton:  D03010 Benoxaprofen:  D03080 Benzydamine (DG00014):  D01410 D07516 D07517 Darbufelone mesylate:  D03652 Docebenone:  D03882 Enazadrem phosphate:  D03990 Fenleuton:  D04151 Linazolast:  D09850 Lonapalene:  D04770 Oxatomide:  D01773<JP> Piriprost (DG02899):  D05498 D05499 Setileuton:  D09667 Tebufelone:  D06017 Tepoxalin:  D06075 Zileuton:  D00414<US> Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00590 Arachidonic acid metabolism     240 (ALOX5)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     240 (ALOX5)  09150 Organismal Systems   09151 Immune system    04664 Fc epsilon RI signaling pathway     240 (ALOX5)   09152 Endocrine system    04913 Ovarian steroidogenesis     240 (ALOX5)   09156 Nervous system    04726 Serotonergic synapse     240 (ALOX5)  09160 Human Diseases   09174 Infectious disease: parasitic    05145 Toxoplasmosis     240 (ALOX5) Enzymes [BR:hsa01000]  1. Oxidoreductases   1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)    1.13.11  With incorporation of two atoms of oxygen     1.13.11.34  arachidonate 5-lipoxygenase      240 (ALOX5) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Lipoxygenase PLAT Motif Other DBs NCBI-GeneID:  240 NCBI-ProteinID:  NP_000689 OMIM:  152390 HGNC:  435 Ensembl:  ENSG00000012779 UniProt:  P09917 Structure PDB LinkDB All DBs Position 10:45374216..45446117 Genome browser AA seq 674 aa AA seqDB search MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDE ELGEIQLVRIEKRKYWLNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAKLA RDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVL NYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNG CNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDP CTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDF HVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECG LFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWE AIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYL TVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCW HLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNKKKQLPY YYLSPDRIPNSVAI NT seq 2025 nt NT seq  +upstreamnt  +downstreamnt atgccctcctacacggtcaccgtggccactggcagccagtggttcgccggcactgacgac tacatctacctcagcctcgtgggctcggcgggctgcagcgagaagcacctgctggacaag cccttctacaacgacttcgagcgtggcgcggtggattcatacgacgtgactgtggacgag gaactgggcgagatccagctggtcagaatcgagaagcgcaagtactggctgaatgacgac tggtacctgaagtacatcacgctgaagacgccccacggggactacatcgagttcccctgc taccgctggatcaccggcgatgtcgaggttgtcctgagggatggacgcgcaaagttggcc cgagatgaccaaattcacattctcaagcaacaccgacgtaaagaactggaaacacggcaa aaacaatatcgatggatggagtggaaccctggcttccccttgagcatcgatgccaaatgc cacaaggatttaccccgtgatatccagtttgatagtgaaaaaggagtggactttgttctg aattactccaaagcgatggagaacctgttcatcaaccgcttcatgcacatgttccagtct tcttggaatgacttcgccgactttgagaaaatctttgtcaagatcagcaacactatttct gagcgggtcatgaatcactggcaggaagacctgatgtttggctaccagttcctgaatggc tgcaaccctgtgttgatccggcgctgcacagagctgcccgagaagctcccggtgaccacg gagatggtagagtgcagcctggagcggcagctcagcttggagcaggaggtccagcaaggg aacattttcatcgtggactttgagctgctggatggcatcgatgccaacaaaacagacccc tgcacactccagttcctggccgctcccatctgcttgctgtataagaacctggccaacaag attgtccccattgccatccagctcaaccaaatcccgggagatgagaaccctattttcctc ccttcggatgcaaaatacgactggcttttggccaaaatctgggtgcgttccagtgacttc cacgtccaccagaccatcacccaccttctgcgaacacatctggtgtctgaggtttttggc attgcaatgtaccgccagctgcctgctgtgcaccccattttcaagctgctggtggcacac gtgagattcaccattgcaatcaacaccaaggcccgtgagcagctcatctgcgagtgtggc ctctttgacaaggccaacgccacagggggcggtgggcacgtgcagatggtgcagagggcc atgaaggacctgacctatgcctccctgtgctttcccgaggccatcaaggcccggggcatg gagagcaaagaagacatcccctactacttctaccgggacgacgggctcctggtgtgggaa gccatcaggacgttcacggccgaggtggtagacatctactacgagggcgaccaggtggtg gaggaggacccggagctgcaggacttcgtgaacgatgtctacgtgtacggcatgcggggc cgcaagtcctcaggcttccccaagtcggtcaagagccgggagcagctgtcggagtacctg accgtggtgatcttcaccgcctccgcccagcacgccgcggtcaacttcggccagtacgac tggtgctcctggatccccaatgcgcccccaaccatgcgagccccgccaccgactgccaag ggcgtggtgaccattgagcagatcgtggacacgctgcccgaccgcggccgctcctgctgg catctgggtgcagtgtgggcgctgagccagttccaggaaaacgagctgttcctgggcatg tacccagaagagcattttatcgagaagcctgtgaaggaagccatggcccgattccgcaag aacctcgaggccattgtcagcgtgattgctgagcgcaacaagaagaagcagctgccatat tactacttgtccccagaccggattccgaacagtgtggccatctga

Homo sapiens (human): 242 Help Entry 242               CDS       T01001                                  Symbol ALOX12B, 12R-LOX, ARCI2 Name (RefSeq) arachidonate 12-lipoxygenase, 12R type   KO K08021   arachidonate 12-lipoxygenase (R-type) [EC:1.13.11.-] Organism hsa  Homo sapiens (human) Pathway hsa00590   Arachidonic acid metabolism hsa01100   Metabolic pathways hsa04726   Serotonergic synapse Disease H00734   Autosomal recessive congenital ichthyosis Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00590 Arachidonic acid metabolism     242 (ALOX12B)  09150 Organismal Systems   09156 Nervous system    04726 Serotonergic synapse     242 (ALOX12B) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Lipoxygenase PLAT Motif Other DBs NCBI-GeneID:  242 NCBI-ProteinID:  NP_001130 OMIM:  603741 HGNC:  430 Ensembl:  ENSG00000179477 UniProt:  O75342 LinkDB All DBs Position 17:complement(8072636..8087716) Genome browser AA seq 701 aa AA seqDB search MATYKVRVATGTDLLSGTRDSISLTIVGTQGESHKQLLNHFGRDFATGAVGQYTVQCPQD LGELIIIRLHKERYAFFPKDPWYCNYVQICAPNGRIYHFPAYQWMDGYETLALREATGKT TADDSLPVLLEHRKEEIRAKQDFYHWRVFLPGLPSYVHIPSYRPPVRRHRNPNRPEWNGY IPGFPILINFKATKFLNLNLRYSFLKTASFFVRLGPMALAFKVRGLLDCKHSWKRLKDIR KIFPGKKSVVSEYVAEHWAEDTFFGYQYLNGVNPGLIRRCTRIPDKFPVTDDMVAPFLGE GTCLQAELEKGNIYLADYRIMEGIPTVELSGRKQHHCAPLCLLHFGPEGKMMPIAIQLSQ TPGPDCPIFLPSDSEWDWLLAKTWVRYAEFYSHEAIAHLLETHLIAEAFCLALLRNLPMC HPLYKLLIPHTRYTVQINSIGRAVLLNEGGLSAKGMSLGVEGFAGVMVRALSELTYDSLY LPNDFVERGVQDLPGYYYRDDSLAVWNALEKYVTEIITYYYPSDAAVEGDPELQSWVQEI FKECLLGRESSGFPRCLRTVPELIRYVTIVIYTCSAKHAAVNTGQMEFTAWMPNFPASMR NPPIQTKGLTTLETFMDTLPDVKTTCITLLVLWTLSREPDDRRPLGHFPDIHFVEEAPRR SIEAFRQRLNQISHDIRQRNKCLPIPYYYLDPVLIENSISI NT seq 2106 nt NT seq  +upstreamnt  +downstreamnt atggccacctacaaagtcagggtggccacaggcaccgacctcttgtcgggaacacgggac tccatctcactgaccattgtggggacacaaggagagagccataagcagctgctgaaccac tttgggagagactttgcaactggggcggtgggccagtacaccgtgcagtgccctcaggac ctgggtgagctcatcatcatccgcctgcacaaagagcggtacgccttcttccccaaggac ccttggtactgcaactatgtgcagatctgtgcccccaacggccgtatctaccacttcccc gcctaccagtggatggatggctacgagaccctggcactccgggaggccacaggaaagaca acagcagatgactcgctccccgtcctcctggagcacagaaaagaggagatcagagccaag caggacttctaccactggcgagtctttcttcctggcctgcccagctatgtgcacattccc agttaccgccctccggtgcggaggcatcgcaaccccaaccggcctgagtggaatggctat attccgggattcccaattctcatcaactttaaggccaccaagttcctgaacttaaatctc cgctactccttcctcaagacggcctccttcttcgtccgcctggggcccatggcactggct ttcaaagtccgcggcctgttggactgcaaacattcgtggaagaggctgaaggacattagg aaaattttccctggcaagaaatctgtcgtctccgagtacgtggccgagcactgggcagag gacaccttctttgggtaccagtacctcaacggcgtcaaccccggcctgatccgccgctgc acgcggatcccagacaagttccccgtcacagacgacatggtggctccgttcctgggcgag ggaacgtgcttgcaagcggagctggagaaggggaacatttacctggccgactaccgcatc atggagggcatccccaccgtggagctcagcggccggaagcagcaccactgcgcccccctc tgcctgctgcactttggacccgagggcaagatgatgcccatcgccatccagctcagccag acccctgggccagattgccccatcttcctgcccagtgattctgagtgggactggctgcta gccaagacgtgggtacgctatgcggagttctacagccacgaggccatcgcccacctgctg gagacacacctcattgctgaggccttctgcctggccttgctgaggaacctgcccatgtgc caccccctctacaagctcctcatcccccatacccgatacaccgtccagatcaacagcatt ggccgggccgttctcctcaatgagggggggctctctgccaagggcatgtccctgggcgtg gaaggctttgctggggtgatggtacgggctctgtcggagctcacctatgacagcctctac ctccccaatgactttgtggagcgtggggtccaggacctgcctggatattactaccgcgat gacagcttggcggtgtggaatgcactggagaagtatgtgacggagatcatcacctattat tacccgagtgacgcagccgtggagggtgatccggaattgcagtcttgggtgcaggaaata tttaaagagtgcctcctggggcgggagagctcaggcttccctaggtgcttgcgaaccgtg cctgagctgatccgatatgtcactatagtcatctacacctgctctgccaagcacgctgct gtcaacacaggccagatggagttcaccgcctggatgcccaacttcccagcgtccatgcgg aatccaccgattcagactaaggggctgaccactctggagaccttcatggacacgttgccg gatgtgaagaccacgtgcatcacgctgctggtgctctggaccctcagccgagagcctgac gacaggcggcccctgggacacttcccggacattcacttcgtggaggaggccccgcggagg agcatagaggcgttccgccagcgcctgaaccagatctcacacgacatccgccagcgcaac aagtgccttcccatcccctactactacctggacccggtgctgattgagaacagcatttct atttag

Homo sapiens (human): 246 Help Entry 246               CDS       T01001                                  Symbol ALOX15, 12-LOX, 15-LOX, 15-LOX-1, LOG15 Name (RefSeq) arachidonate 15-lipoxygenase   KO K00460   arachidonate 15-lipoxygenase [EC:1.13.11.33] Organism hsa  Homo sapiens (human) Pathway hsa00590   Arachidonic acid metabolism hsa00591   Linoleic acid metabolism hsa01100   Metabolic pathways hsa04148   Efferocytosis hsa04216   Ferroptosis hsa04217   Necroptosis hsa04726   Serotonergic synapse Network nt06525  Ferroptosis nt06535  Efferocytosis   Element N01590   Arachidonate/Adrenic acid metabolism N01781   Activation of LXRs by oxysterols Drug target Utreloxastat:  D12510 Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00590 Arachidonic acid metabolism     246 (ALOX15)    00591 Linoleic acid metabolism     246 (ALOX15)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     246 (ALOX15)   09143 Cell growth and death    04216 Ferroptosis     246 (ALOX15)    04217 Necroptosis     246 (ALOX15)  09150 Organismal Systems   09156 Nervous system    04726 Serotonergic synapse     246 (ALOX15) Enzymes [BR:hsa01000]  1. Oxidoreductases   1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)    1.13.11  With incorporation of two atoms of oxygen     1.13.11.33  arachidonate 15-lipoxygenase      246 (ALOX15) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Lipoxygenase PLAT Motif Other DBs NCBI-GeneID:  246 NCBI-ProteinID:  NP_001131 OMIM:  152392 HGNC:  433 Ensembl:  ENSG00000161905 UniProt:  P16050 LinkDB All DBs Position 17:complement(4630919..4641678) Genome browser AA seq 662 aa AA seqDB search MGLYRIRVSTGASLYAGSNNQVQLWLVGQHGEAALGKRLWPARGKETELKVEVPEYLGPL LFVKLRKRHLLKDDAWFCNWISVQGPGAGDEVRFPCYRWVEGNGVLSLPEGTGRTVGEDP QGLFQKHREEELEERRKLYRWGNWKDGLILNMAGAKLYDLPVDERFLEDKRVDFEVSLAK GLADLAIKDSLNVLTCWKDLDDFNRIFWCGQSKLAERVRDSWKEDALFGYQFLNGANPVV LRRSAHLPARLVFPPGMEELQAQLEKELEGGTLFEADFSLLDGIKANVILCSQQHLAAPL VMLKLQPDGKLLPMVIQLQLPRTGSPPPPLFLPTDPPMAWLLAKCWVRSSDFQLHELQSH LLRGHLMAEVIVVATMRCLPSIHPIFKLIIPHLRYTLEINVRARTGLVSDMGIFDQIMST GGGGHVQLLKQAGAFLTYSSFCPPDDLADRGLLGVKSSFYAQDALRLWEIIYRYVEGIVS LHYKTDVAVKDDPELQTWCREITEIGLQGAQDRGFPVSLQARDQVCHFVTMCIFTCTGQH ASVHLGQLDWYSWVPNAPCTMRLPPPTTKDATLETVMATLPNFHQASLQMSITWQLGRRQ PVMVAVGQHEEEYFSGPEPKAVLKKFREELAALDKEIEIRNAKLDMPYEYLRPSVVENSV AI NT seq 1989 nt NT seq  +upstreamnt  +downstreamnt atgggtctctaccgcatccgcgtgtccactggggcctcgctctatgccggttccaacaac caggtgcagctgtggctggtcggccagcacggggaggcggcgctcgggaagcgactgtgg cccgcacggggcaaggagacagaactcaaggtggaagtaccggagtatctggggccgctg ctgtttgtgaaactgcgcaaacggcacctccttaaggacgacgcctggttctgcaactgg atctctgtgcagggccccggagccggggacgaggtcaggttcccttgttaccgctgggtg gagggcaacggcgtcctgagcctgcctgaaggcaccggccgcactgtgggcgaggaccct cagggcctgttccagaaacaccgggaagaagagctggaagagagaaggaagttgtaccgg tggggaaactggaaggacgggttaattctgaatatggctggggccaaactatatgacctc cctgtggatgagcgatttctggaagacaagagagttgactttgaggtttcgctggccaag gggctggccgacctcgctatcaaagactctctaaatgttctgacttgctggaaggatcta gatgacttcaaccggattttctggtgtggtcagagcaagctggctgagcgcgtgcgggac tcctggaaggaagatgccttatttgggtaccagtttcttaatggcgccaaccccgtggtg ctgaggcgctctgctcaccttcctgctcgcctagtgttccctccaggcatggaggaactg caggcccagctggagaaggagctggagggaggcacactgttcgaagctgacttctccctg ctggatgggatcaaggccaacgtcattctctgtagccagcagcacctggctgcccctcta gtcatgctgaaattgcagcctgatgggaaactcttgcccatggtcatccagctccagctg ccccgcacaggatccccaccacctccccttttcttgcctacggatcccccaatggcctgg cttctggccaaatgctgggtgcgcagctctgacttccagctccatgagctgcagtctcat cttctgaggggacacttgatggctgaggtcattgttgtggccaccatgaggtgcctgccg tcgatacatcctatcttcaagcttataattccccacctgcgatacaccctggaaattaac gtccgggccaggactgggctggtctctgacatgggaattttcgaccagataatgagcact ggtgggggaggccacgtgcagctgctcaagcaagctggagccttcctaacctacagctcc ttctgtccccctgatgacttggccgaccgggggctcctgggagtgaagtcttccttctat gcccaagatgcgctgcggctctgggaaatcatctatcggtatgtggaaggaatcgtgagt ctccactataagacagacgtggctgtgaaagacgacccagagctgcagacctggtgtcga gagatcactgaaatcgggctgcaaggggcccaggaccgagggtttcctgtctctttacag gctcgggaccaggtttgccactttgtcaccatgtgtatcttcacctgcaccggccaacac gcctctgtgcacctgggccagctggactggtactcttgggtgcctaatgcaccctgcacg atgcggctgcccccgccaaccaccaaggatgcaacgctggagacagtgatggcgacactg cccaacttccaccaggcttctctccagatgtccatcacttggcagctgggcagacgccag cccgttatggtggctgtgggccagcatgaggaggagtatttttcgggccctgagcctaag gctgtgctgaagaagttcagggaggagctggctgccctggataaggaaattgagatccgg aatgcaaagctggacatgccctacgagtacctgcggcccagcgtggtggaaaacagtgtg gccatctaa

Homo sapiens (human): 247 Help Entry 247               CDS       T01001                                  Symbol ALOX15B, 15-LOX-2 Name (RefSeq) arachidonate 15-lipoxygenase type B   KO K08022   arachidonate 15-lipoxygenase (second type) / 8-lipoxygenase (S-type) [EC:1.13.11.33 1.13.11.-] Organism hsa  Homo sapiens (human) Pathway hsa00590   Arachidonic acid metabolism hsa01100   Metabolic pathways hsa04726   Serotonergic synapse Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00590 Arachidonic acid metabolism     247 (ALOX15B)  09150 Organismal Systems   09156 Nervous system    04726 Serotonergic synapse     247 (ALOX15B) Enzymes [BR:hsa01000]  1. Oxidoreductases   1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)    1.13.11  With incorporation of two atoms of oxygen     1.13.11.33  arachidonate 15-lipoxygenase      247 (ALOX15B) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Lipoxygenase PLAT DNA_pol3_tau_4 Motif Other DBs NCBI-GeneID:  247 NCBI-ProteinID:  NP_001132 OMIM:  603697 HGNC:  434 Ensembl:  ENSG00000179593 UniProt:  O15296 Structure PDB LinkDB All DBs Position 17:8039059..8049134 Genome browser AA seq 676 aa AA seqDB search MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKEFTAGAEEDFQVTLPED VGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQE GTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAK NANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFAS QFLNGLNPVLIRRCHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQT NVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWV RNAEFSFHEALTHLLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELL IVPGQVVDRSTGIGIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQI WGAVERFVSEIIGIYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQ YVTMVIFTCSAKHAAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNAT CDVILALWLLSKEPGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVL PYTYLDPPLIENSVSI NT seq 2031 nt NT seq  +upstreamnt  +downstreamnt atggccgagttcagggtcagggtgtccaccggagaagccttcggggctggcacatgggac aaagtgtctgtcagcatcgtggggacccggggagagagccccccactgcccctggacaat ctcggcaaggagttcactgcgggcgctgaggaggacttccaggtgacgctcccggaggac gtaggccgagtgctgctgctgcgcgtgcacaaggcgcccccagtgctgcccctgctgggg cccctggccccggatgcctggttctgccgctggttccagctgacaccgccgcggggcggc cacctcctcttcccctgctaccagtggctggagggggcggggaccctggtgctgcaggag ggtacagccaaggtgtcctgggcagaccaccaccctgtgctccagcaacagcgccaggag gagcttcaggcccggcaggagatgtaccagtggaaggcttacaacccaggttggcctcac tgcctggatgaaaagacagtggaagacttggagctcaatatcaaatactccacagccaag aatgccaacttttatctacaggctggctctgcttttgcagagatgaaaatcaaggggttg ctggaccgcaaggggctctggaggagtctgaatgagatgaaaaggatcttcaacttccgg aggaccccagcagctgagcacgcatttgagcactggcaggaggacgccttcttcgcctcc cagttcctgaatggtctcaaccctgtcctgatccgccgctgtcactacctcccaaagaac ttccccgtcactgatgccatggtggcctcagtgttgggtcctgggaccagcttgcaggct gagctagagaagggctccctgttcttggtggatcacggcatcctctctggcatccagacc aatgtcattaatgggaagcctcagttctctgcggccccaatgaccctgctataccagagc ccaggctgcgggccgctgctgcctctcgccatccagctcagccagacccccggcccaaac agccccatcttcctgcccactgatgacaagtgggactggttgctggccaagacctgggtg cgcaatgccgagttctccttccatgaggccctcacgcacctgctgcactcacatctgctg cctgaggtcttcaccctggctaccctgcgtcagctgccccactgccaccctctcttcaag ctgctgatcccgcacacccgatacaccctgcacatcaacacactcgcccgggagctgctt atcgtgccagggcaggtggtggacaggtccacaggcatcggcattgaaggcttctctgag ttgatacagaggaacatgaagcagctgaactattctctcctgtgtctgcctgaggatatc cggacccgaggagttgaagacatcccaggctactactaccgtgatgatgggatgcagatc tggggtgcagtggaacgctttgtctctgaaatcatcggtatctactacccaagtgatgag tctgtccaagatgacagagagctccaggcctgggtcagagagatcttctccaagggcttc ctaaaccaggagagctcaggtataccctcctcactggagacccgggaagccctggtgcag tatgtcaccatggtgatattcacctgctccgccaagcatgcggctgtcagtgcagggcag tttgactcctgtgcttggatgcccaacctgccacccagcatgcagctgccaccacccacc tccaaaggcctggcaacatgcgagggcttcatagccaccctcccacctgtcaatgccaca tgtgatgtcatccttgctctctggttgctgagcaaggagcctggagaccaaaggcccctg ggcacctatccggatgagcacttcacagaggaggcccctcggcggagcatcgccaccttc cagagccgcctggcccagatctcgaggggcatccaggagcggaaccagggcctggtgctg ccctacacctacctagaccctcccctcatcgagaacagcgtctccatctaa

DBGET integrated database retrieval system