Homo sapiens (human): 7094 Help Entry 7094              CDS       T01001                                  Symbol TLN1, ILWEQ, TLN, talin-1 Name (RefSeq) talin 1   KO K06271   talin Organism hsa  Homo sapiens (human) Pathway hsa04015   Rap1 signaling pathway hsa04510   Focal adhesion hsa04611   Platelet activation hsa04820   Cytoskeleton in muscle cells hsa05131   Shigellosis hsa05166   Human T-cell leukemia virus 1 infection Network nt06182  Shigella nt06539  Cytoskeleton in muscle cells   Element N01080   ITGA/B-TALIN/VINCULIN signaling pathway N01081   Shigella IpaB/C/D to ITGA/B-TALIN/VINCULIN signaling pathway N01815   Vinculin-talin-integrin macromolecular complex Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     7094 (TLN1)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     7094 (TLN1)   09142 Cell motility    04820 Cytoskeleton in muscle cells     7094 (TLN1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     7094 (TLN1)  09160 Human Diseases   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     7094 (TLN1)   09171 Infectious disease: bacterial    05131 Shigellosis     7094 (TLN1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     7094 (TLN1) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    7094 (TLN1)   Exosomal proteins of other cancer cells    7094 (TLN1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Talin_IBS2B TLN1-like_RS VBS Talin_middle Talin_R4 I_LWEQ FERM_f0 IRS FERM_M RA_2 FERM_N ACBP TrcR RA GIT1_C Motif Other DBs NCBI-GeneID:  7094 NCBI-ProteinID:  NP_006280 OMIM:  186745 HGNC:  11845 Ensembl:  ENSG00000137076 UniProt:  Q9Y490 Structure PDB LinkDB All DBs Position 9:complement(35696948..35732195) Genome browser AA seq 2541 aa AA seqDB search MVALSLKISIGNVVKTMQFEPSTMVYDACRIIRERIPEAPAGPPSDFGLFLSDDDPKKGI WLEAGKALDYYMLRNGDTMEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICARIG ITNHDEYSLVRELMEEKKEEITGTLRKDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTL REQGVEEHETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAG FQCQIQFGPHNEQKHKAGFLDLKDFLPKEYVKQKGERKIFQAHKNCGQMSEIEAKVRYVK LARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKECVMRVDEKTKEVIQEWNLTNIKRWA ASPKSFTLDFGDYQDGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTML EDSVSPKKSTVLQQQYNRVGKVEHGSVALPAIMRSGASGPENFQVGSMPPAQQQITSGQM HRGHMPPLTSAQQALTGTINSSMQAVQAAQATLDDFDTLPPLGQDAASKAWRKNKMDESK HEIHSQVDAITAGTASVVNLTAGDPAETDYTAVGCAVTTISSNLTEMSRGVKLLAALLED EGGSGRPLLQAAKGLAGAVSELLRSAQPASAEPRQNLLQAAGNVGQASGELLQQIGESDT DPHFQDALMQLAKAVASAAAALVLKAKSVAQRTEDSGLQTQVIAAATQCALSTSQLVACT KVVAPTISSPVCQEQLVEAGRLVAKAVEGCVSASQAATEDGQLLRGVGAAATAVTQALNE LLQHVKAHATGAGPAGRYDQATDTILTVTENIFSSMGDAGEMVRQARILAQATSDLVNAI KADAEGESDLENSRKLLSAAKILADATAKMVEAAKGAAAHPDSEEQQQRLREAAEGLRMA TNAAAQNAIKKKLVQRLEHAAKQAAASATQTIAAAQHAASTPKASAGPQPLLVQSCKAVA EQIPLLVQGVRGSQAQPDSPSAQLALIAASQSFLQPGGKMVAAAKASVPTIQDQASAMQL SQCAKNLGTALAELRTAAQKAQEACGPLEMDSALSVVQNLEKDLQEVKAAARDGKLKPLP GETMEKCTQDLGNSTKAVSSAIAQLLGEVAQGNENYAGIAARDVAGGLRSLAQAARGVAA LTSDPAVQAIVLDTASDVLDKASSLIEEAKKAAGHPGDPESQQRLAQVAKAVTQALNRCV SCLPGQRDVDNALRAVGDASKRLLSDSLPPSTGTFQEAQSRLNEAAAGLNQAATELVQAS RGTPQDLARASGRFGQDFSTFLEAGVEMAGQAPSQEDRAQVVSNLKGISMSSSKLLLAAK ALSTDPAAPNLKSQLAAAARAVTDSINQLITMCTQQAPGQKECDNALRELETVRELLENP VQPINDMSYFGCLDSVMENSKVLGEAMTGISQNAKNGNLPEFGDAISTASKALCGFTEAA AQAAYLVGVSDPNSQAGQQGLVEPTQFARANQAIQMACQSLGEPGCTQAQVLSAATIVAK HTSALCNSCRLASARTTNPTAKRQFVQSAKEVANSTANLVKTIKALDGAFTEENRAQCRA ATAPLLEAVDNLSAFASNPEFSSIPAQISPEGRAAMEPIVISAKTMLESAGGLIQTARAL AVNPRDPPSWSVLAGHSRTVSDSIKKLITSMRDKAPGQLECETAIAALNSCLRDLDQASL AAVSQQLAPREGISQEALHTQMLTAVQEISHLIEPLANAARAEASQLGHKVSQMAQYFEP LTLAAVGAASKTLSHPQQMALLDQTKTLAESALQLLYTAKEAGGNPKQAAHTQEALEEAV QMMTEAVEDLTTTLNEAASAAGVVGGMVDSITQAINQLDEGPMGEPEGSFVDYQTTMVRT AKAIAVTVQEMVTKSNTSPEELGPLANQLTSDYGRLASEAKPAAVAAENEEIGSHIKHRV QELGHGCAALVTKAGALQCSPSDAYTKKELIECARRVSEKVSHVLAALQAGNRGTQACIT AASAVSGIIADLDTTIMFATAGTLNREGTETFADHREGILKTAKVLVEDTKVLVQNAAGS QEKLAQAAQSSVATITRLADVVKLGAASLGAEDPETQVVLINAVKDVAKALGDLISATKA AAGKVGDDPAVWQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALEATTEHIRQELAVF CSPEPPAKTSTPEDFIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRRAIADMLRACK EAAYHPEVAPDVRLRALHYGRECANGYLELLDHVLLTLQKPSPELKQQLTGHSKRVAGSV TELIQAAEAMKGTEWVDPEDPTVIAENELLGAAAAIEAAAKKLEQLKPRAKPKEADESLN FEEQILEAAKSIAAATSALVKAASAAQRELVAQGKVGAIPANALDDGQWSQGLISAARMV AAATNNLCEAANAAVQGHASQEKLISSAKQVAASTAQLLVACKVKADQDSEAMKRLQAAG NAVKRASDNLVKAAQKAAAFEEQENETVVVKEKMVGGIAQIIAAQEEMLRKERELEEARK KLAQIRQQQYKFLPSELRDEH NT seq 7626 nt NT seq  +upstreamnt  +downstreamnt atggttgcactttcactgaagatcagcattgggaatgtggtgaagacgatgcagtttgag ccgtctaccatggtgtacgacgcctgccgcatcattcgtgagcggatcccagaggcccca gctggtcctcccagcgactttgggctctttctgtcagatgatgaccccaaaaagggtata tggctggaggctgggaaagctttggactactacatgctccgaaatggggacactatggag tacaggaagaaacagagacccctgaagatccgtatgctggatggaactgtgaagacgatc atggtggatgactctaagactgtcactgacatgctcatgaccatctgtgcccgcattggc atcaccaatcatgatgaatattcattggttcgagagctgatggaagagaaaaaggaggaa ataacagggaccttaagaaaggacaagacattgctgcgagatgaaaagaagatggagaaa ctaaagcagaaattgcacacagatgatgagttgaactggctggaccatggtcggacactg agggagcagggtgtagaggagcacgagacgctgctgctgcggaggaagttcttttactca gaccagaatgtggattcccgggaccctgtacagctgaacctcctgtatgtgcaggcacga gatgacatcctgaatggctcccaccctgtctcctttgacaaggcctgtgagtttgctggc ttccaatgccagatccagtttgggccccacaatgagcagaagcacaaggctggcttcctt gacctgaaggacttcctgcccaaggagtatgtgaagcagaagggagagcgtaagatcttc caggcacacaagaattgtgggcagatgagtgagattgaggccaaggtccgctacgtgaag ctagcccgttctctcaagacttacggtgtctccttcttcctggtgaaggaaaaaatgaaa gggaagaacaagctagtgcccaggcttctgggcatcaccaaggagtgtgtgatgcgagtg gatgagaagaccaaggaagtgatccaggagtggaacctcaccaacatcaaacgctgggct gcgtctcccaaaagcttcaccctggattttggagattaccaagatggctattactcagta cagacaactgaaggggagcagattgcacagctcattgccggctacatcgatatcatcctg aagaagaaaaaaagcaaggatcactttgggctggaaggagatgaggagtctactatgctg gaggactcagtgtcccccaaaaagtcaacagtcctgcagcagcaatacaaccgggtgggg aaagtggagcatggctctgtggccctgcctgccatcatgcgctctggagcctctggtcct gagaatttccaggtgggcagcatgccccctgcccagcagcagattaccagcggccagatg caccgaggacacatgcctcctctgacttcagcccagcaggcactcactggaaccattaac tccagcatgcaggccgtgcaggctgcccaggccaccctggatgactttgacactctgccg cctcttggccaggatgctgcctctaaggcctggcgtaaaaacaagatggatgaatcaaag catgagatccactctcaggtagatgccatcacagctggtactgcgtctgtggtgaacctg acagcaggggaccctgctgagacagactataccgcagtgggctgtgcagtcaccacaatc tcctccaacctgacggagatgtcccgtggggtgaagctgctggctgccttgctggaggac gaaggcggcagtggtcggcccctgttgcaggcagcaaagggccttgcgggagcagtgtca gaactgctgcgcagtgcccaaccagccagtgctgagccccgtcagaacctgctgcaagca gctgggaacgtgggccaggccagtggggagctgttgcaacaaattggggaaagtgatact gacccccacttccaggatgcgctaatgcagctcgccaaagctgtggcaagtgctgcagct gccctggtcctcaaggccaagagtgtggcccagcggacagaggactcgggacttcagacc caagttattgctgcagcaacacagtgtgccctatccacttcccaactagtggcctgtact aaggtggtggcacctacaatcagctcacctgtctgccaagagcaactggtggaggctgga cgactggtagccaaagccgtggagggctgtgtgtctgcctcccaggcagctacagaggat gggcaactgttgcgaggggtaggagcagcagccacagctgtcacccaggccctaaatgag ctgctgcagcatgtgaaagcccatgccacaggggctgggcctgctggccgttatgaccag gctactgacaccatcctaaccgtcactgagaacatctttagctccatgggtgatgctggg gagatggtgcgacaggcccgcatcctggcccaagccacatctgacctggtcaatgccatc aaggctgatgctgagggggaaagtgatctggagaactcccgcaagctcttaagtgctgcc aagatcctagctgatgccacagccaagatggtagaggctgccaagggagcagctgcccac cctgacagtgaggagcagcagcagcggctgcgggaggcagctgaggggctgcgcatggcc accaatgcagctgcgcagaatgccatcaagaaaaagctggtgcagcgcctggagcatgca gccaagcaggctgcagcctcagccacacagaccatcgctgcagctcagcacgcagcctct acccccaaggcctctgccggcccccagcccctgctggtgcagagctgcaaggcagtggca gagcagattccactgctggtgcagggcgtccgaggaagccaagcccagcctgacagcccc agcgctcagcttgccctcattgctgccagccagagcttcctgcagccaggtgggaagatg gtggcagctgcaaaggcctcagtgccaacgattcaggaccaggcttcagccatgcagctg agtcagtgtgccaagaacctgggcaccgcgctggctgaactccggacggctgcccagaag gctcaggaagcatgtggacctttggagatggattctgcactgagtgtggtacagaatcta gagaaagatctacaggaagtgaaggcagcagctcgagatggcaagcttaaacccttacct ggggagacaatggagaagtgtacccaggacctgggcaacagcaccaaagccgtgagctca gccatcgcccagctactgggagaggttgcccagggcaatgagaattatgcaggtattgca gctcgggatgtggcaggtgggctgcggtcactggcccaggccgctaggggagtcgctgca ctgacgtcagatcctgcagtgcaggccattgtacttgatacggccagtgatgtgctggac aaggccagcagcctcattgaggaggcgaaaaaggcagctggccatccaggggaccctgag agccagcagcggcttgcccaggtggctaaagcagtgacccaggctctgaaccgctgtgtc agctgcctacctggccagcgcgatgtggataatgccctgagggcagttggagatgccagc aagcgactcctgagtgactcgcttcctcctagcactgggacatttcaagaagctcagagc cggttgaatgaagctgctgctgggctgaatcaggcagccacagaactggtgcaggcctct cggggaacccctcaggacctggctcgagcctcaggccgatttggacaggacttcagcacc ttcctggaagctggtgtggagatggcaggccaggctccgagccaggaggaccgagcccaa gttgtgtccaacttgaagggcatctccatgtcttcaagcaaacttcttctggctgccaag gccctgtccacggaccctgctgcccctaacctcaagagtcagctggctgcagctgccagg gcagtaactgacagcatcaatcagctcatcactatgtgcacccagcaggcacccggccag aaggagtgtgataacgccctgcgggaattggagacggtccgggaactcctggagaaccca gtccagcccatcaatgacatgtcctactttggttgcctggacagtgtaatggagaactca aaggtgctgggcgaggccatgactggcatctcccaaaatgccaagaacggaaacctgcca gagtttggagatgccatttccacagcctcaaaggcactttgtggcttcaccgaggcagct gcacaggctgcatatctggttggtgtctctgaccccaatagccaagctggacagcaaggg ctagtggagcccacacagtttgcccgtgcaaaccaggcaattcagatggcctgccagagt ttgggagagcctggctgtacccaggcccaggtgctctctgcagccaccattgtggctaaa cacacctctgcactgtgtaacagctgtcgcctggcttctgcccgtaccaccaatcctact gccaagcgccagtttgtacagtcagccaaggaggtggccaacagcacagctaatcttgtc aagaccatcaaggcgctagatggggccttcacagaggagaaccgtgcccagtgccgagca gcaacagcccctctgctggaggctgtggacaatctgagtgcctttgcgtccaaccctgag ttctccagcattcctgcccagatcagccctgagggtcgggctgccatggagcccattgtg atctctgccaagacaatgttagagagtgccgggggactcatccagacagcccgggccctc gcagtcaatccccgggaccccccgagctggtcggtgctggccggccactcccgtactgtc tcagactccatcaagaagctaattacaagcatgagggacaaggctccagggcagctggag tgtgaaacggccattgcagctctgaacagttgtctacgggacctagaccaggcttccctc gctgcagtcagccagcagcttgctccccgtgagggaatctctcaagaggccttgcacact cagatgctcactgcagtccaagagatctcccatctcattgagccgctggccaatgctgcc cgggctgaagcctcccagctgggacacaaggtgtcccagatggcgcagtactttgagccg ctcaccctggctgcagtgggtgctgcctccaagaccctgagccacccgcagcagatggca ctcctggaccagactaaaacattggcagagtctgccctgcagttgctatacactgccaag gaggctggtggtaacccaaagcaagcagctcacacccaggaagccctggaggaggctgtg cagatgatgaccgaggccgtagaggacctgacaacaaccctcaacgaggcagccagtgct gctggggtcgtgggtggcatggtggactccatcacccaggccatcaaccagctagatgaa ggaccaatgggtgaaccagaaggttccttcgtggattaccaaacaactatggtgcggaca gccaaggccattgcagtgaccgttcaggagatggttaccaagtcaaacaccagcccagag gagctgggccctcttgctaaccagctgaccagtgactatggccgtctggcctcggaggcc aagcctgcagcggtggctgctgaaaatgaagagataggttcccatatcaaacaccgggta caggagctgggccatggctgtgccgctctggtcaccaaggcaggcgccctgcagtgcagc cccagtgatgcctacaccaagaaggagctcatagagtgtgcccggagagtctctgagaag gtctcccacgtcctggctgcgctccaggctgggaatcgtggcacccaggcctgcatcaca gcagccagcgctgtgtctggtatcattgctgacctcgacaccaccatcatgttcgccact gctggcacgctcaatcgtgagggtactgaaactttcgctgaccaccgggagggcatcctg aagactgcgaaggtgctggtggaggacaccaaggtcctggtgcaaaacgcagctgggagc caggagaagttggcgcaggctgcccagtcctccgtggcgaccatcacccgcctcgctgat gtggtcaagctgggtgcagccagcctgggagctgaggaccctgagacccaggtggtacta atcaacgcagtgaaagatgtagccaaagccctgggagacctcatcagtgcaacgaaggct gcagctggcaaagttggagatgaccctgctgtgtggcagctaaagaactctgccaaggtg atggtgaccaatgtgacatcattgcttaagacagtaaaagccgtggaagatgaggccacc aaaggcactcgggccctggaggcaaccacagaacacatacggcaggagctggcggttttc tgttccccagagccacctgccaagacctctaccccagaagacttcatccgaatgaccaag ggtatcaccatggcaaccgccaaggccgttgctgctggcaattcctgtcgccaggaagat gtcattgccacagccaatctgagccgccgtgctattgcagatatgcttcgggcttgcaag gaagcagcttaccacccagaagtggcccctgatgtgcggcttcgagccctgcactatggc cgggagtgtgccaatggctacctggaactgctggaccatgtactgctgaccctgcagaag ccaagcccagaactgaagcagcagttgacaggacattcaaagcgtgtggctggttccgtc actgagctcatccaggctgctgaagccatgaagggaacagaatgggtagacccagaggac cccacagtcattgctgagaatgagctcctgggagctgcagccgccattgaggctgcagcc aaaaagctagagcagctgaagccccgggccaaacccaaggaggcagatgagtccttgaac tttgaggagcagatactagaagctgccaagtccattgcagcagccaccagtgcactggta aaggctgcgtcggctgcccagagagaactagtggcccaagggaaggtgggtgccattcca gccaatgcactggacgatgggcagtggtcccagggcctcatttctgctgcccggatggtg gctgcggccaccaacaatctgtgtgaggcagccaatgcagctgtacaaggccatgccagc caggagaagctcatctcatcagccaagcaggtagctgcctccacagcccagctccttgtg gcctgcaaggtcaaggctgaccaggactcggaggcaatgaaacgacttcaggctgctggc aacgcagtgaagcgagcctcagataatctggtgaaagcagcacagaaggctgcagccttt gaagagcaggagaatgagacagtggtggtgaaagagaagatggttggcggcattgcccag atcatcgcagcacaggaagaaatgcttcggaaggaacgagagctggaagaggcgcggaag aaactggcccagatccggcagcagcagtacaagtttctgccttcagagcttcgagatgag cactaa

Homo sapiens (human): 83660 Help Entry 83660             CDS       T01001                                  Symbol TLN2, ILWEQ Name (RefSeq) talin 2   KO K06271   talin Organism hsa  Homo sapiens (human) Pathway hsa04015   Rap1 signaling pathway hsa04510   Focal adhesion hsa04611   Platelet activation hsa04820   Cytoskeleton in muscle cells hsa05131   Shigellosis hsa05166   Human T-cell leukemia virus 1 infection Network nt06182  Shigella nt06539  Cytoskeleton in muscle cells   Element N01080   ITGA/B-TALIN/VINCULIN signaling pathway N01081   Shigella IpaB/C/D to ITGA/B-TALIN/VINCULIN signaling pathway N01815   Vinculin-talin-integrin macromolecular complex Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     83660 (TLN2)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     83660 (TLN2)   09142 Cell motility    04820 Cytoskeleton in muscle cells     83660 (TLN2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     83660 (TLN2)  09160 Human Diseases   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     83660 (TLN2)   09171 Infectious disease: bacterial    05131 Shigellosis     83660 (TLN2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     83660 (TLN2) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    83660 (TLN2)   Exosomal proteins of other cancer cells    83660 (TLN2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Talin_IBS2B TLN1-like_RS VBS Talin_middle I_LWEQ Talin_R4 FERM_f0 IRS FERM_M RA_2 FERM_N ACBP OTU1_UBXL Motif Other DBs NCBI-GeneID:  83660 NCBI-ProteinID:  NP_055874 OMIM:  607349 HGNC:  15447 Ensembl:  ENSG00000171914 UniProt:  Q9Y4G6 Structure PDB LinkDB All DBs Position 15:62390550..62844631 Genome browser AA seq 2542 aa AA seqDB search MVALSLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRK GIWLEAGRTLDYYMLRNGDILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSR IGITNYEEYSLIQETIEEKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSR TFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEF GGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNCGEMSEIEAKVK YVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVK RWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEES TMLEESVSPKKSTILQQQFNRTGKAEHGSVALPAVMRSGSSGPETFNVGSMPSPQQQVMV GQMHRGHMPPLTSAQQALMGTINTSMHAVQQAQDDLSELDSLPPLGQDMASRVWVQNKVD ESKHEIHSQVDAITAGTASVVNLTAGDPADTDYTAVGCAITTISSNLTEMSKGVKLLAAL MDDEVGSGEDLLRAARTLAGAVSDLLKAVQPTSGEPRQTVLTAAGSIGQASGDLLRQIGE NETDERFQDVLMSLAKAVANAAAMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLV ACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVRACQAATTDSELLKQVSAAASVVSQA LHDLLQHVRQFASRGEPIGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLV NAMRSDAEAEIDMENSKKLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGL RVATNAAAQNAIKKKIVNRLEVAAKQAAAAATQTIAASQNAAVSNKNPAAQQQLVQSCKA VADHIPQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAAM QLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALNTVQTLKNELQDAKMAAVESQLKP LPGETLEKCAQDLGSTSKAVGSSMAQLLTCAAQGNEHYTGVAARETAQALKTLAQAARGV AASTTDPAAAHAMLDSARDVMEGSAMLIQEAKQALIAPGDAERQQRLAQVAKAVSHSLNN CVNCLPGQKDVDVALKSIGESSKKLLVDSLPPSTKPFQEAQSELNQAAADLNQSAGEVVH ATRGQSGELAAASGKFSDDFDEFLDAGIEMAGQAQTKEDQIQVIGNLKNISMASSKLLLA AKSLSVDPGAPNAKNLLAAAARAVTESINQLITLCTQQAPGQKECDNALRELETVKGMLD NPNEPVSDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTE AAAQAAYLVGISDPNSQAGHQGLVDPIQFARANQAIQMACQNLVDPGSSPSQVLSAATIV AKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKC RIATAPLIEAVENLTAFASNPEFVSIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTAR SLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQA SLAAVSQSLATRDDISVEALQEQLTSVVQEIGHLIDPIATAARGEAAQLGHKVTQLASYF EPLILAAVGVASKILDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAQHTHDAITEA AQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEGTPPEPKGTFVDYQTTVVK YSKAIAVTAQEMMTKSVTNPEELGGLASQMTSDYGHLAFQGQMAAATAEPEEIGFQIRTR VQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARAVTEKVSLVLSALQAGNKGTQACI TAATAVSGIIADLDTTIMFATAGTLNAENSETFADHRENILKTAKALVEDTKLLVSGAAS TPDKLAQAAQSSAATITQLAEVVKLGAASLGSDDPETQVVLINAIKDVAKALSDLISATK GAASKPVDDPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIECIKQELTV FQSKDVPEKTSSPEESIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRKAVSDMLTAC KQASFHPDVSDEVRTRALRFGTECTLGYLDLLEHVLVILQKPTPEFKQQLAAFSKRVAGA VTELIQAAEAMKGTEWVDPEDPTVIAETELLGAAASIEAAAKKLEQLKPRAKPKQADETL DFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVGSIPANAADDGQWSQGLISAARM VAAATSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQAA GNAVKRASDNLVRAAQKAAFGKADDDDVVVKTKFVGGIAQIIAAQEEMLKKERELEEARK KLAQIRQQQYKFLPTELREDEG NT seq 7629 nt NT seq  +upstreamnt  +downstreamnt atggtggccctgtccttaaagatttgtgtgcgccactgcaacgtggtgaagaccatgcag tttgaaccatctacagctgtgtacgatgcgtgtcgagtcattcgggaacgggtgcctgag gcacaaactgggcaagcttctgactatggactctttctttcggatgaagacccgaggaaa gggatttggctggaagcgggcagaacactggattactacatgttgcggaatggggatatt ttggaatataaaaagaaacagagacctcagaaaatccggatgctggatggatctgtgaag acagtgatggtggatgattccaagactgtgggggagctcctggtcactatttgtagcaga ataggaataacaaattatgaagaatactccttaatccaagaaactattgaagaaaagaaa gaggaaggaacgggcacactcaaaaaagacaggacactgttacgagatgagaggaaaatg gagaagttgaaggccaagctgcacacagatgatgacctaaattggctggatcacagccga acattcagagaacaaggagtagatgaaaacgaaacgttgctgcttagacggaagttcttt tactctgatcagaatgtagattcgagagaccccgtgcagctgaacttgctttatgttcag gcacgggatgacatcctgaatggctctcaccctgtctccttcgagaaagcttgtgagttt ggtggatttcaagcccagatacaatttggacctcatgtggaacataaacacaaacctgga tttttagatctgaaggaattcctgcccaaagaatatatcaagcagagaggagctgaaaag aggatctttcaggagcataagaactgcggagagatgagtgagatagaagccaaggtcaag tacgtcaaactcgcacggtccctccgcacatatggcgtgtccttcttcctggtgaaggag aagatgaaaggcaagaacaagctggtgcctcgcctgctggggatcaccaaagactcggtg atgcgcgtggatgagaagaccaaggaagtgctgcaggagtggcccctcaccaccgtcaag cgctgggcagcctcacccaagagcttcacactggattttggggagtatcaggaaagctac tattcagtacaaaccaccgagggagagcagatatcccagctgattgcaggctacattgac atcatcctgaaaaagaaacaaagtaaagatcgatttggactagaaggtgatgaggagtca accatgttagaagagtccgtttccccaaaaaagtccaccatcttgcagcagcagttcaac cggaccgggaaggcagagcacggctcagtggcgctgccggccgtgatgcgctcgggctcc agcgggcctgagaccttcaacgttggcagcatgccctcgccacagcagcaggtcatggtt gggcagatgcaccgaggccacatgccgccactgacctcagcccagcaggccctgatgggg accatcaacacaagcatgcacgccgtccagcaggcccaggatgatctcagtgagctcgac tcgctgccacctctcggccaggatatggcatctagggtatgggttcagaacaaagtcgac gaatccaaacacgaaatccattctcaagttgatgctatcacggccggaacggcttcagtt gttaacctcacagctggtgaccctgcagacactgactacacagctgtgggatgtgcgatc accactatttcttccaacctgacggagatgtccaagggtgtgaagctattggccgccctc atggatgatgaggtgggcagcggggaggacttgctcagagctgccaggaccctcgctggg gcggtgtcagacttgctgaaagctgtgcagcctacttctggagagcctcgacagacagtt ttgactgctgctggcagcatcggacaagccagtggggatcttctgagacagattggagag aatgagactgatgagcgattccaggatgttttaatgagtttggccaaagctgttgccaat gcagctgccatgttggtactaaaggcaaagaatgttgcccaagtggccgaagacactgtc ctacagaacagggtaattgctgctgccacccagtgtgccctctccacctcccagcttgtg gcatgtgccaaggttgtgagccccactattagctcccctgtgtgccaggagcagctgatt gaagcagggaagctggtggaccgctcggtggagaactgtgtccgtgcctgccaggcggcc actaccgatagtgagctcctgaagcaggtcagcgcagcggccagcgtggtcagccaggcc ctccatgatctcctgcagcatgtgcggcagtttgccagccgaggcgagcccatcggccgc tacgaccaggctactgacaccatcatgtgtgtcaccgagagcatcttcagctccatgggt gacgctggtgaaatggtgcgccaggcgcgggttctggcccaagccacatcagacctcgtc aatgccatgaggtcagatgcagaagccgaaatcgacatggagaattcaaagaagctcctg gcagcagcaaaactcttagctgactccactgctcgcatggtggaagctgcaaagggggct gcagccaacccagagaatgaggaccagcagcaaaggctgagagaagctgcagaaggcctc cgggtagcaaccaacgcagctgcccagaatgctattaagaaaaaaattgtcaaccgactg gaggttgcagccaagcaggccgcagcggcagccacacagaccatcgccgcctcccagaat gcagctgtttccaacaagaaccctgcggcccagcagcagctggtccagagttgcaaggca gtggctgatcacatccctcagctggtccagggagtgagggggagccaagctcaagctgaa gacctgagtgcccagctggctctcatcatctccagccagaacttcctccagcctggaagc aagatggtgtcctctgccaaagccgcagtgcccaccgtgagtgaccaggccgcagccatg cagctgagccagtgtgccaagaacctggccaccagcttggcggagctgcgtaccgcctcg cagaaggcccatgaagcttgtggtccgatggaaatcgattcagctctgaatacggtgcag acgcttaagaatgaactgcaggatgccaagatggcagccgtggagagccagctgaagcca cttccaggggaaacgctggaaaaatgtgctcaggacctgggaagcacatccaaggcggtg ggctcctccatggcacagctgctgacctgtgctgctcaaggcaacgaacactacacaggg gtggctgctagagagacggcccaagctctgaaaacactggcccaggccgcccgtggagtg gctgcatcgacaaccgaccccgcggccgcccatgccatgttagattctgctcgagacgtg atggagggctccgccatgctcattcaagaggccaagcaggccctgattgcacctggagat gcagagcgtcaacaaagactggctcaggtggctaaagccgtctcacactccttgaataac tgcgtaaattgcctccctgggcagaaggatgtggacgtggccttgaagagcatcggggag tccagcaagaagctgcttgtggattcgctacctccaagcacgaagcctttccaggaagcc cagagtgaactgaaccaggcagcagctgatctgaaccagtctgctggggaagtggtccat gccacccggggccagagtggagagttggctgcagcctctggaaagttcagtgatgatttt gatgaattcctcgatgctggcattgagatggctggccaagctcagacaaaagaagaccag atccaagtgatagggaacctcaagaatatctcgatggcatccagcaagctgctgttagct gccaagtctctctctgtagatccaggagctcccaatgcgaaaaatctcctggctgcagct gcaagagctgtgacagagagcatcaatcaactcatcactctgtgtacccaacaagctccg ggccagaaagagtgcgataatgccctgcgggagctcgagactgtgaaggggatgttggac aatcctaatgaacctgttagtgacctctcttactttgactgcattgagagtgtgatggaa aactccaaggttctgggtgaatcgatggcagggatttcacagaatgccaagaccggagac ctccctgcctttggggaatgtgtggggattgcatccaaggctctctgtgggctgacagag gctgcagcccaggctgcatacttggttggcatctctgatccaaacagccaggcaggccac cagggcctggtggaccccatccagtttgccagggctaaccaggccatccagatggcatgc cagaacttggtggaccctggcagcagcccatcacaggtcctgtcagccgccacaattgtt gccaagcacacgtcagccttgtgcaatgcctgccgcatcgcctcatccaagacggccaac ccagtagccaagaggcacttcgtccagtcagccaaggaagtcgccaacagcactgccaac ctggtgaagaccatcaaggccctggatggggatttctctgaagacaaccgcaataagtgt cgcatcgccaccgcacccttgattgaagctgtggagaacctgacagcgttcgcctcaaac cctgagtttgtcagcattcctgcccagatcagctccgagggttcccaggcacaggaacca atcctggtctcagccaagaccatgctggagagttcatcgtacctcattcgcactgcacgc tctctggccatcaaccccaaagacccacccacctggtctgtactggctggacattcccat acagtgtccgactccatcaagagtctcatcacttctatcagggacaaggcccctggacag agggagtgtgattactccatcgatggcatcaaccggtgcatccgggacatcgagcaggcc tcgctggccgccgtcagccagagcctggccacgagggacgacatctctgtggaggccctg caggagcagctgacttcggtggtccaggaaatcggacaccttatcgatcccatcgccaca gcggctcggggagaagcagctcagctgggacataaggtgacacaactggcaagctatttt gagcccttgatcttagccgcagttggtgtggcctccaagattcttgatcatcagcagcag atgacggtgctggaccagaccaagactctcgcagagtctgccttgcagatgttgtatgca gccaaagaaggtggcggaaaccccaaggcacaacacacccatgacgccatcacagaggcc gcccagttgatgaaggaagccgtggatgacatcatggtgacgctgaacgaagctgccagt gaagtggggctggttgggggcatggtggacgccattgcagaagccatgagcaagctggat gaaggcactcctccagaaccaaagggaacatttgtcgactatcagacgactgtggttaaa tactccaaagccattgcggtgacagctcaggaaatgatgactaagtcggttactaacccg gaggagttgggaggactggcttcacaaatgaccagtgactatgggcacctggctttccag ggccagatggcagcagccacggcggaaccagaggagatcggattccagattcgcactcgt gtgcaggacctgggccacggctgtatcttcctggtgcagaaggcaggggccctccaggtc tgccccacagacagctacaccaagagggagctgatcgaatgcgcccgtgccgtcacggaa aaggtctccttggtgctctcggctctccaggccgggaacaaaggaacccaggcatgcatt acagccgccaccgctgtgtctgggatcattgccgacctggacaccaccattatgtttgca acagcggggacgctgaatgcagagaacagtgagaccttcgcagaccacagggagaacatt ctcaagacggccaaggccttggtagaagacacgaaactacttgtgtcaggagctgcgtcc actcctgacaagctggcccaggcggcccagtcctcagcagccaccatcacccagctcgca gaagtggtcaagctgggggcagccagcctgggctccgacgaccccgagacccaggtggtt ttgatcaatgccatcaaagatgtggccaaggccctttctgatctcatcagtgctaccaag ggagctgccagcaagccagtggacgacccttccatgtaccagctcaagggggctgccaag gtgatggtgaccaatgtcacctcgctcctcaagactgtaaaggcagtggaggatgaggcc acccggggcaccagggcgcttgaggccacaattgaatgcataaagcaggagcttacggtg ttccagtcaaaagacgtacctgaaaagacatcatcacctgaagaatccataaggatgacg aaaggcatcaccatggcaacagccaaagccgtggcagctgggaactcatgtagacaggag gacgtgattgctactgccaacctgagccggaaagccgtgtcagatatgttgacggcttgc aagcaagcatccttccaccccgatgtcagtgacgaggtgagaaccagagccttgcgtttc gggacggagtgcacccttggctacttggacctcctggagcacgtcttggtgattcttcag aaaccaaccccagaattcaagcagcagctggccgctttctccaagcgagtcgccggcgct gtgacagagctcatccaggcggcggaagccatgaaaggaacagagtgggtggatccagaa gacccaactgtcattgcagaaacagagttactgggggctgcagcatccatcgaagctgct gctaagaagttagagcaactgaagccaagagcaaaaccaaaacaagcggatgagaccctg gactttgaggaacagatcttggaagctgctaaatccattgctgctgccacaagcgccctg gtcaaatcggcctcagcagcccagagggagctggtggcccaaggaaaggtgggctccatc cctgccaatgctgcagacgacggacagtggtcacaggggctgatttctgctgcccggatg gtggcggctgcgaccagcagtctctgtgaggcggccaatgcctccgttcagggacacgcc agcgaggagaagctcatctcatctgccaagcaggtcgccgcttccacggctcagctgctg gtggcctgcaaggtgaaggccgaccaggattcagaggccatgaggcggctacaggcggca ggaaatgctgtgaaaagagcctcagacaatcttgtccgtgcagcccagaaggcagctttt ggcaaagctgatgacgacgatgttgtagtgaaaaccaagtttgtggggggcattgctcag atcatcgccgcccaggaagaaatgctaaagaaagagcgagaactggaagaagcaaggaaa aaactggcccaaatccgccagcagcagtataagtttttacccaccgagctgagggaagat gagggctaa

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