Homo sapiens (human): 7417
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Entry
7417 CDS
T01001
Symbol
VDAC2, POR
Name
(RefSeq) voltage dependent anion channel 2
KO
K15040
voltage-dependent anion channel protein 2
Organism
hsa
Homo sapiens (human)
Pathway
hsa04020
Calcium signaling pathway
hsa04022
cGMP-PKG signaling pathway
hsa04216
Ferroptosis
hsa04217
Necroptosis
hsa04218
Cellular senescence
hsa04613
Neutrophil extracellular trap formation
hsa04621
NOD-like receptor signaling pathway
hsa04979
Cholesterol metabolism
hsa05010
Alzheimer disease
hsa05012
Parkinson disease
hsa05016
Huntington disease
hsa05017
Spinocerebellar ataxia
hsa05020
Prion disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05166
Human T-cell leukemia virus 1 infection
hsa05208
Chemical carcinogenesis - reactive oxygen species
hsa05415
Diabetic cardiomyopathy
Network
nt06410
Calcium signaling
nt06460
Alzheimer disease
nt06461
Huntington disease
nt06462
Spinocerebellar ataxia
nt06463
Parkinson disease
nt06464
Amyotrophic lateral sclerosis
nt06465
Prion disease
Element
N00957
Mutation-caused abberant ATXN2/3 to mGluR5-Ca2+ -apoptotic pathway
N00967
VGCC-Ca2+ -apoptotic pathway
N00984
mGluR5-Ca2+ -apoptotic pathway
N00985
Mutation-caused aberrant Htt to mGluR5-Ca2+ -apoptotic pathway
N00987
Mutation-caused aberrant Htt to transport of calcium
N01000
mAChR-Ca2+ -apoptotic pathway
N01001
Mutation-caused aberrant Abeta to mAchR-Ca2+ -apoptotic pathway
N01002
Mutation-caused aberrant Abeta to mGluR5-Ca2+ -apoptotic pathway
N01003
Mutation-caused aberrant Abeta to transport of calcium
N01004
Mutation-caused aberrant Abeta to VGCC-Ca2+ -apoptotic pathway
N01006
Mutation-caused aberrant Abeta to VGCC-Ca2+ -apoptotic pathway
N01007
Mutation-caused aberrant PSEN to mGluR5-Ca2+ -apoptotic pathway
N01008
Mutation-caused aberrant PSEN1 to mGluR5-Ca2+ -apoptotic pathway
N01031
Mutation-caused aberrant SNCA to VGCC-Ca2+ -apoptotic pathway
N01151
Mutation-inactivated SIGMAR1 to Ca2+ -apoptotic pathway
N01199
Scrapie conformation PrPSc to mGluR5-Ca2+ -apoptotic pathway
N01200
Scrapie conformation PrPSc to transport of calcium
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
7417 (VDAC2)
04022 cGMP-PKG signaling pathway
7417 (VDAC2)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
7417 (VDAC2)
04217 Necroptosis
7417 (VDAC2)
04218 Cellular senescence
7417 (VDAC2)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
7417 (VDAC2)
04621 NOD-like receptor signaling pathway
7417 (VDAC2)
09154 Digestive system
04979 Cholesterol metabolism
7417 (VDAC2)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
7417 (VDAC2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
7417 (VDAC2)
09164 Neurodegenerative disease
05010 Alzheimer disease
7417 (VDAC2)
05012 Parkinson disease
7417 (VDAC2)
05016 Huntington disease
7417 (VDAC2)
05017 Spinocerebellar ataxia
7417 (VDAC2)
05020 Prion disease
7417 (VDAC2)
05022 Pathways of neurodegeneration - multiple diseases
7417 (VDAC2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
7417 (VDAC2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03029 Mitochondrial biogenesis [BR:
hsa03029
]
7417 (VDAC2)
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hsa04040
]
7417 (VDAC2)
Mitochondrial biogenesis [BR:
hsa03029
]
Mitochondrial protein import machinery
Outer membrane
Porin
7417 (VDAC2)
Ion channels [BR:
hsa04040
]
Chloride channels
Maxi chloride channel (VDAC)
7417 (VDAC2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Porin_3
Motif
Other DBs
NCBI-GeneID:
7417
NCBI-ProteinID:
NP_001171752
OMIM:
193245
HGNC:
12672
Ensembl:
ENSG00000165637
Pharos:
P45880
(Tchem)
UniProt:
P45880
A0A024QZT0
LinkDB
All DBs
Position
10:75210170..75231448
Genome browser
AA seq
294 aa
AA seq
DB search
MATHGQTCARPMCIPPSYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNT
DTGKVTGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGK
KSGKIKSSYKRECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRNNF
AVGYRTGDFQLHTNVNDGTEFGGSIYQKVCEDLDTSVNLAWTSGTNCTRFGIAAKYQLDP
TASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSINAGGHKVGLALELEA
NT seq
885 nt
NT seq
+upstream
nt +downstream
nt
atggcgacccacggacagacttgcgcgcgtccaatgtgtattcctccatcatatgctgac
cttggcaaagctgccagagatattttcaacaaaggatttggttttgggttggtgaaactg
gatgtgaaaacaaagtcttgcagtggcgtggaattttcaacgtccggttcatctaataca
gacactggtaaagttactgggaccttggagaccaaatacaagtggtgtgagtatggtctg
actttcacagaaaagtggaacactgataacactctgggaacagaaatcgcaattgaagac
cagatttgtcaaggtttgaaactgacatttgatactaccttctcaccaaacacaggaaag
aaaagtggtaaaatcaagtcttcttacaagagggagtgtataaaccttggttgtgatgtt
gactttgattttgctggacctgcaatccatggttcagctgtctttggttatgagggctgg
cttgctggctaccagatgacctttgacagtgccaaatcaaagctgacaaggaataacttt
gcagtgggctacaggactggggacttccagctacacactaatgtcaatgatgggacagaa
tttggaggatcaatttatcagaaagtttgtgaagatcttgacacttcagtaaaccttgct
tggacatcaggtaccaactgcactcgttttggcattgcagctaaatatcagttggatccc
actgcttccatttctgcaaaagtcaacaactctagcttaattggagtaggctatactcag
actctgaggcctggtgtgaagcttacactctctgctctggtagatgggaagagcattaat
gctggaggccacaaggttgggctcgccctggagttggaggcttaa
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