KEGG   PATHWAY: hsb00230
Entry
hsb00230                    Pathway                                
Name
Purine metabolism - Hymenobacter sublimis
Class
Metabolism; Nucleotide metabolism
Pathway map
hsb00230  Purine metabolism
hsb00230

Module
hsb_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:hsb00230]
hsb_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:hsb00230]
hsb_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:hsb00230]
hsb_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:hsb00230]
hsb_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:hsb00230]
hsb_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:hsb00230]
Other DBs
GO: 0006163 0042278
Organism
Hymenobacter sublimis [GN:hsb]
Gene
MWH26_11485  phospho-sugar mutase [KO:K01835] [EC:5.4.2.2]
MWH26_02330  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
MWH26_16125  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
MWH26_16135  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
MWH26_16130  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
MWH26_16160  phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
MWH26_16165  AIR synthase-related protein [KO:K23270] [EC:6.3.5.3]
MWH26_16120  AIR synthase-related protein [KO:K01933] [EC:6.3.3.1]
MWH26_04805  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
MWH26_03650  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
MWH26_04810  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
MWH26_16155  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
MWH26_12220  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
MWH26_01230  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
MWH26_13270  metallophosphatase [KO:K01081] [EC:3.1.3.5]
MWH26_07645  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
MWH26_03835  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
MWH26_02805  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
MWH26_14360  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
MWH26_01340  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
MWH26_02570  FAD binding domain-containing protein [KO:K13481] [EC:1.17.1.4]
MWH26_02565  molybdopterin-dependent oxidoreductase [KO:K13482] [EC:1.17.1.4]
MWH26_03105  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
MWH26_05680  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
MWH26_10180  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
MWH26_11075  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
MWH26_05675  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
MWH26_10185  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
MWH26_11070  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
MWH26_05670  (2Fe-2S)-binding protein [KO:K13483]
MWH26_10190  2Fe-2S iron-sulfur cluster-binding protein [KO:K13483]
MWH26_11065  2Fe-2S iron-sulfur cluster-binding protein [KO:K13483]
MWH26_06125  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
MWH26_06315  nucleoside deaminase [KO:K01487] [EC:3.5.4.3]
MWH26_15045  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
MWH26_17290  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
MWH26_17280  ribonucleoside-diphosphate reductase small subunit [KO:K00526] [EC:1.17.4.1]
MWH26_06105  dgt; dNTP triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
MWH26_12285  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
MWH26_06710  phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MWH26_14690  phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
MWH26_12270  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
MWH26_03430  deoxynucleoside kinase [KO:K15519] [EC:2.7.1.76 2.7.1.74]
MWH26_05720  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
MWH26_01985  ade; adenine deaminase [KO:K01486] [EC:3.5.4.2]
MWH26_02810  adenylate kinase [KO:K00939] [EC:2.7.4.3]
MWH26_06235  GTP-binding protein [KO:K00956] [EC:2.7.7.4]
MWH26_06240  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
hsb00030  Pentose phosphate pathway
hsb00220  Arginine biosynthesis
hsb00250  Alanine, aspartate and glutamate metabolism
hsb00260  Glycine, serine and threonine metabolism
hsb00340  Histidine metabolism
hsb00630  Glyoxylate and dicarboxylate metabolism
hsb00730  Thiamine metabolism
hsb00740  Riboflavin metabolism
hsb00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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